A Guide to Forensic DNA Profiling

Forensic Botany: A Practical Guide is an accessible introduction to the way in which botanical evidence is identified, collected and analysed in criminal cases. Increasingly this form of evidence is becoming more important in forensic investigation and yet there are few trained botanists able to assist in such cases. This book is intended to show how useful simple collection methods and standard plant analysis can be in the course of such investigations and is written in a clear and accessible manner to enhance understanding of the subject for the non-specialist. Clearly structured throughout, this book combines well known collection techniques in a field oriented format that can be used for casework. Collection of evidence differs from formal plant collection in that most professional plant collectors are gathering entire plants or significant portions of a plant for permanent storage and reference. Evidence frequently consists of fragments, sometimes exceedingly tiny. Exemplars (examples of reference plants) are collections of plants made in the manner a botanist would collect them. These collections are necessary to link or exclude evidence to or from a scene. Various methods that allow easy collection, transportation, and preservation of evidence are detailed throughout the book. This book is written for those who have no formal background working with plants. It can be used as a practical guide for students taking forensic science courses, law enforcement training, legal courses, and as a template for plant collection at any scene where plants occur and where rules or laws are involved. Veterinarians, various environmental agencies, anthropologists, and archeologists are examples of disciplines that are more recently in need of plant evidence. Veterinarians are becoming more active in pursuing cases of animals that have been abused or are victims of illegal killing. Anthropologists and archeologists are often called to help with body recovery in outdoor environments. Environmental agencies are increasingly forced to adopt rules for resource protection, are in need of a guide for procedures for plant evidence collection and application. The format of the book is designed to present the reader with all the information needed to conduct a botanical analysis of a crime scene; to highlight the forensic significance of the botanical evidence that may be present; how to collect that evidence in the correct manner and preserve and store that evidence appropriately- also shows how to conduct a laboratory analysis of the plants.

Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on: * Image analysis * Experiment design * Automated analysis, integrated analysis, and systems biology * Interpretation of results Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.

DNA typing of non-human DNA is a fast developing area of research and professional practice. The application of DNA typing in wildlife forensic science is one of these prime uses of DNA typing and is gaining increasing profile. The use of DNA profiling in wildlife forensic science falls into two broad areas: species testing and genetic linkage. Species testing answers the question ‘what species is this?’ and genetic linkage answers the question ‘did these two samples come from the same organism or population?’ Wildlife DNA Analysis: Applications in Forensic Science provides an accessible introduction to both of these key areas. Clearly structured throughout, the introduction highlights the different types of crime where these techniques are regularly used. This chapter includes a discussion as to who performs forensic wildlife examinations, the standardisation and validation of methods, and the role of the expert witness in this type of alleged crime. This is followed by a detailed section on the science behind DNA typing including the problems in isolating DNA from trace material and subsequent genetic analysis are also covered. The book then undertakes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons. A comparison of the different markers used in species testing highlights the criteria for a genetic marker. A full set of case histories illustrates the use of the different markers used. The book details the use of genetic markers to link two or more hairs/feather/leaves/needles to the same individual organism and the software used in population assignment. The problems and possibilities in isolating markers, along with the construction of allele databases are discussed in this chapter. The book concludes with evaluation and reporting of genetic evidence in wildlife forensic science illustrated by examples of witness statements. •An accessible introduction to this fast developing area of research within forensic science •Case studies throughout to link theory and practice and to highlight the use of DNA testing in species testing. •Covers both crimes against wildlife and offences where wildlife can provide vital evidence •Assumes only a basic background knowledge of DNA •Includes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons

Assessing Weight-of-Evidence for DNA Profiles is an excellent introductory text to the use of statistical analysis for assessing DNA evidence. It offers practical guidance to forensic scientists with little dependence on mathematical ability as the book includes background information on statistics – including likelihood ratios – population genetics, and courtroom issues. The author, who is highly experienced in this field, has illustrated the book throughout with his own experiences as well as providing a theoretical underpinning to the subject. It is an ideal choice for forensic scientists and lawyers, as well as statisticians and population geneticists with an interest in forensic science and DNA.

DNA evidence is widely used in the modern justice system. Statistical methodology plays a key role in ensuring that this evidence is collected, interpreted, analysed and presented correctly. This book is a guide to assessing DNA evidence and presenting that evidence in a courtroom setting. It offers practical guidance to forensic scientists with little dependence on mathematical ability, and provides the scientist with the understanding they require to apply the methods in their work. Since the publication of the first edition of this book in 2005 there have been many incremental changes, and one dramatic change which is the emergence of low template DNA (LTDNA) profiles. This second edition is edited and expanded to cover the basics of LTDNA technology. The author's own open-source R code likeLTD is described and used for worked examples in the book. Commercial and free software are also covered.

An Introduction to Forensic Genetics is a comprehensive introduction to this fast moving area from the collection of evidence at the scene of a crime to the presentation of that evidence in a legal context. The last few years have seen significant advances in the subject and the development and application of genetics has revolutionised forensic science. This book begins with the key concepts needed to fully appreciate the subject and moves on to examine the latest developments in the field, illustrated throughout with references to relevant casework. In addition to the technology involved in generating a DNA profile, the underlying population biology and statistical interpretation are also covered. The evaluation and presentation of DNA evidence in court is discussed as well with guidance on the evaluation process and how court reports and statements should be presented. An accessible introduction to Forensic Genetics from the collection of evidence to the presentation of that evidence in a legal context Includes case studies to enhance student understanding Includes the latest developments in the field focusing on the technology used today and that which is likely to be used in the future Accessible treatment of population biology and statistics associated with forensic evidence This book offers undergraduate students of Forensic Science an accessible approach to the subject that will have direct relevance to their courses. An Introduction to Forensic Genetics is also an invaluable resource for postgraduates and practising forensic scientists looking for a good introduction to the field.

This book is a guide to the extraordinarily diverse literature of the Hellenistic period. A guide to the literature of the Hellenistic age, from the death of Alexander the Great in 323 BCE to the Battle of Actium in 31 BC Provides overviews of the social, political, intellectual and literary historical contexts in which Hellenistic literature was produced Introduces the major writers and genres of the period Provides information about style, meter and languages to aid readers with no prior knowledge of the language in understanding technical aspects of literary Greek Distinctive in its coverage of current issues in Hellenistic criticism, including audience reception, the political and social background, and Hellenistic theories of literature

The first book devoted exclusively to the principles and practice of genetic counseling—now in a new edition First published in 1998, A Guide to Genetic Counseling quickly became a bestselling and widely recognized text, used nationally and internationally in genetic counseling training programs. Now in its eagerly anticipated Second Edition, it provides a thoroughly revised and comprehensive overview of genetic counseling, focusing on the components, theoretical framework, and unique approach to patient care that are the basis of this profession. The book defines the core competencies and covers the genetic counseling process from case initiation to completion—in addition to addressing global professional issues—with an emphasis on describing fundamental principles and practices. Chapters are written by leaders in the field of genetic counseling and are organized to facilitate academic instruction and skill attainment. They provide the most up-to-date coverage of: The history and practice of genetic counseling Family history Interviewing Case preparation and management Psychosocial counseling Patient education Risk communication and decision-making Medical genetics evaluation Understanding genetic testing Medical documentation Multicultural counseling Ethical and legal issues Student supervision Genetic counseling research Professional development Genetics education and outreach Evolving roles and expanding opportunities Case examples A Guide to Genetic Counseling, Second Edition belongs on the syllabi of all medical and human genetics and genetic counseling training programs. It is an indispensable reference for both students and healthcare professionals working with patients who have or are at risk for genetic conditions.

The field of forensic archaeology has developed over recent years from being a branch of conventional archaeology into a well-established discipline in its own right. Forensic Approaches to Buried Remains takes an innovative approach to the subject by placing the role of the forensic archaeologist within the wider forensic environment; it identifies new areas of interdisciplinary research and practice, and evaluates practical difficulties. The authors see this book as a reflection of the subject’s development, and as a knowledge base for the next generation of forensic archaeologists. Areas covered include: Search logistics, integration and specialist search scenarios Levels of confidence in site search and elimination Urban and rural landscape reconstruction in both short and long term cases The integration of cadaver dogs and earth-moving machinery The recovery of multiple evidence types Sampling strategies, spatial relevance and dating Multiple burial scenarios As part of the Essential Forensic Science book series this book will provide students and practitioners alike with an invaluable resource outlining both the major developments in the discipline, as well as original approaches to the search for, and recovery of buried remains.

A Guide to Teaching Statistics: Innovations and Best Practices addresses the critical aspects of teaching statistics to undergraduate students, acting as an invaluable tool for both novice and seasoned teachers of statistics. Guidance on textbook selection, syllabus construction, and course outline Classroom exercises, computer applications, and Internet resources designed to promote active learning Tips for incorporating real data into course content Recommendations on integrating ethics and diversity topics into statistics education Strategies to assess student's statistical literacy, thinking, and reasoning skills Additional material online at www.teachstats.org