Advanced Techniques in Diagnostic Cellular Pathology

The first book devoted solely to the techniques used to investigate skin problems in animals A practical everyday reference for veterinary practitioners, Diagnostic Techniques in Veterinary Dermatology focuses on contemporary techniques for investigating skin problems in small animals, horses and exotic pets. Written by experienced specialists in veterinary dermatology, this book offers clear, step-by-step guidance on how to perform tests and interpret their results. The first book devoted exclusively to the subject, this hands-on guide demonstrates how to carry out and interpret a huge range of dermatology tests, as well as how to avoid common mistakes and pitfalls. Featuring full colour photographs and illustrations throughout, key topics include: looking for parasites, hair plucks and trichograms, dermoscopy, cytology, fungal and bacterial cultures, histopathology, allergy testing, immune-mediated skin diseases, endocrine and metabolic skin diseases, infectious diseases, diagnostic imaging, otoscopy and examination of the ear, genetic tests, and more. Diagnostic Techniques in Veterinary Dermatology is a valuable working resource for busy practitioners in first opinion practice, as well as veterinary nurses and technicians. It is also an ideal reference for veterinary students and specialists in-training.

The successful design and construction of iconic new buildings relies on a range of advanced technologies, in particular on advanced modelling techniques. In response to the increasingly complex buildings demanded by clients and architects, structural engineers have developed a range of sophisticated modelling software to carry out the necessary structural analysis and design work. Advanced Modelling Techniques in Structural Design introduces numerical analysis methods to both students and design practitioners. It illustrates the modelling techniques used to solve structural design problems, covering most of the issues that an engineer might face, including lateral stability design of tall buildings; earthquake; progressive collapse; fire, blast and vibration analysis; non-linear geometric analysis and buckling analysis . Resolution of these design problems are demonstrated using a range of prestigious projects around the world, including the Buji Khalifa; Willis Towers; Taipei 101; the Gherkin; Millennium Bridge; Millau viaduct and the Forth Bridge, illustrating the practical steps required to begin a modelling exercise and showing how to select appropriate software tools to address specific design problems.

Now in its third edition, Anatomy in Diagnostic Imaging is an unrivalled atlas of anatomy applied to diagnostic imaging. The book covers the entire human body and employs all the imaging modalities used in clinical practice; x-ray, CT, MR, PET, ultrasound and scintigraphy. An introductory chapter explains succinctly the essentials of the imaging and examination techniques drawing on the latest technical developments. In view of the great strides that have been made in this area recently, all chapters have been thoroughly revised in this third edition. The book’s original and didactically convincing presentation has been enhanced with over 250 new images. There are now more than 900 images, all carefully selected in order to be user-friendly and easy-to-read, due to their high quality and the comprehensive anatomical interpretation directly placed alongside every one. Both for medical students and practising doctors, Anatomy in Diagnostic Imaging will serve as the go-to all-round reference collection linking anatomy and modern diagnostic imaging. Winner of the Radiology category at the BMA Book Awards 2015

Clinical Pathology and Laboratory Techniques for Veterinary Technicians provides a comprehensive reference of laboratory procedures featuring ‘how-to’ information as it pertains to small animals, horses, and cattle. An inclusive reference on laboratory procedures pertaining to small animals, horses and cattle Provides information on hematology, hemostasis, clinical chemistry, urinalysis, parasitology, and fecal testing Features high-quality photographs labelled with magnification and stain information, which clearly depict cellular morphology, inclusions and infectious organisms Offers key objectives, technician tip boxes, case examples and a glossary of key terms A companion website provides images from the book for download, instructor questions and answer key to multiple choice questions in the book

Praise for the First Edition « . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students.»—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.

This handbook is designed to help jobbing histopathologists jog their memory and get through more workload in any working day. Rapid access is facilitated by a bullet-point, tabular and diagrammatic style, as well as by handy anatomical diagrams, guidance on the ‘Cut-Up’ with emphasis on core ‘datasets’ and by a special index for frozen section advice, grading systems and scoring systems. The book provides, where useful, differential diagnosis lists and presents diagnostically helpful molecular and immunohistochemical findings. Information is kept up-to-date on a dedicated website www.pathbook.com. The Diagnostic Criteria Handbook in Histopathology is not designed to be an “exam cram” and neither will it serve as a basic text for beginners. Trainees, however, will still benefit from the sheer breadth of topics covered in this one small volume: from lab management and lab methods, to autopsy practice, cytology and all sub-specialties in surgical pathology. A chapter on exam technique and mnemonics makes the book also an essential companion for those revising for professional exams. So why clutter your precious desk space with multiple sets of heavy two-volume reference works? Give this handy Vade Mecum a place next to your microscope and see how much time you could save!

This new version of Frances Barr’s classic introductory text, Diagnostic Ultrasound in the Dog and Cat, has now been revised and expanded to cover the considerable technological and knowledge based advances since the first book was published in 1990. With contributions from leading subject experts, this new book covers both the theoretical principles behind the use of ultrasound in small animal practice and the practical approach to image interpretation. In-keeping with the user-friendly style of Frances Barr’s book, the book is extensively illustrated with photographs and accompanying line drawings. Organised around body systems, each chapter covers imaging procedures, normal appearances, abnormal appearances/diseases and specific conditions. Exotic animals, such as rabbits and reptiles are also included, as are new Doppler techniques. This practical guide is essential reading for all those involved in small animal imaging.

Explore the foundations of modern finance with this intuitive mathematical guide In Mathematical Techniques in Finance: An Introduction , distinguished finance professional Amir Sadr delivers an essential and practical guide to the mathematical foundations of various areas of finance, including corporate finance, investments, risk management, and more. Readers will discover a wealth of accessible information that reveals the underpinnings of business and finance. You’ll learn about: Investment theory, including utility theory, mean-variance theory and asset allocation, and the Capital Asset Pricing Model Derivatives, including forwards, options, the random walk, and Brownian Motion Interest rate curves, including yield curves, interest rate swap curves, and interest rate derivativesComplete with math reviews, useful Excel functions, and a glossary of financial terms, Mathematical Techniques in Finance: An Introduction is required reading for students and professionals in finance.

Minimally invasive surgical techniques are moving into the mainstream of urological practice. Even less invasive techniques, some of which can involve no use of the knife whatsoever, are rapidly being developed and implemented for treating urological cancer. Interventional Techniques in Uro-oncology is the first text to cover these techniques in total and provides a comprehensive review of the state-of-the-art minimally invasive interventions. This well-illustrated reference provides the basic science behind each technique before explaining when and how best to perform them. It examines their use in different clinical settings, the advantages and disadvantages of each technique in the management of specific tumor types, and their suitability for different patients. Future techniques are discussed including the potential of nanotechnology in the delivery of urologic healthcare. Each chapter is easy to navigate with key points and references. Interventional Techniques in Uro-oncology is an essential reference for training and practicing oncologists, urologists and radiologists as well as the general physician with a keen interest in cancer care. Its approachable style will also inform non-experts on what is available and whether a particular intervention is suitable for their patient in the clinic.

Covers powerful new tools for drug development Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular Pathology in Drug Discovery and Development provides an unmatched guide to this cutting-edge discipline and its applications to pharmaceutical science. With contributions from leading lights in drug discovery, drug development, and molecular pathology balanced by a consistent editorial approach, this reference offers both an overview of molecular pathology and a close look at the methods as they are applied to the process of drug discovery and development. Presented as steps in the drug development process, the coverage includes the use of molecular pathology to: Identify and validate new drug candidates Enhance transcriptional profiling to better find and validate biomarkers Assess toxicology Employ toxicogenomics to identify genes relevant to the safety of compounds Identify correct doses for different drugs Identify patients for treatment Develop molecular therapies Further the new techniques of Immunohistochemistry and Immunofluorescence With many tests and treatments already working today, drug research and development using molecular pathology has shown itself an extremely fruitful area. Molecular Pathology in Drug Discovery and Development gives practitioners an up-to-date resource on this highly active discipline and its role in furthering pharmaceutical research.