An Introduction to Pain and its relation to Nervous System Disorders

Comprehensive look at mechanical molecular devices that mimic the behavior of man-made devices Molecular devices and molecular machines are individual molecules and molecular systems capable of providing valuable device-like functions. Many of them have distinct conventional prototypes and therefore can be identified as technomimetic molecules. The last decade has seen an increasing rate of practical applications of molecular devices and machines, primarily in biomedical and material science fields. Molecular devices: An Introduction to Technomimetics and its Biological Applications focuses on mechanical molecular devices, including the early set of technomimetic molecules. Topics covered include the many simple molecular devices such as container compounds, gearing systems, belts and tubes, and tweezers. It touches upon each molecular machine and discusses in great detail the importance of their applications as well as the latest progress in the fields of chemistry, physics, and biotechnology. Interdisciplinary: Must-have content for physicists, chemists, and biologists Comprehensive: Details an extensive set of mechanical technomimetic molecular devices Thorough: Starts with the fundamental material characterization and finishes with real-world device application Molecular devices: An Introduction to Technomimetics and its Biological Applications is an important book for graduate students, researchers, scientists, and engineers in the fields of chemistry, materials science, molecular physics, engineering, biotechnology, and molecular medicine.

A well-balanced introduction to probability theory and mathematical statistics Featuring updated material, An Introduction to Probability and Statistics, Third Edition remains a solid overview to probability theory and mathematical statistics. Divided intothree parts, the Third Edition begins by presenting the fundamentals and foundationsof probability. The second part addresses statistical inference, and the remainingchapters focus on special topics. An Introduction to Probability and Statistics, Third Edition includes: A new section on regression analysis to include multiple regression, logistic regression, and Poisson regression A reorganized chapter on large sample theory to emphasize the growing role of asymptotic statistics Additional topical coverage on bootstrapping, estimation procedures, and resampling Discussions on invariance, ancillary statistics, conjugate prior distributions, and invariant confidence intervals Over 550 problems and answers to most problems, as well as 350 worked out examples and 200 remarks Numerous figures to further illustrate examples and proofs throughout An Introduction to Probability and Statistics, Third Edition is an ideal reference and resource for scientists and engineers in the fields of statistics, mathematics, physics, industrial management, and engineering. The book is also an excellent text for upper-undergraduate and graduate-level students majoring in probability and statistics.

This book recalls the basics required for an understanding of the nanoworld (quantum physics, molecular biology, micro and nanoelectronics) and gives examples of applications in various fields: materials, energy, devices, data management and life sciences. It is clearly shown how the nanoworld is at the crossing point of knowledge and innovation. Written by an expert who spent a large part of his professional life in the field, the title also gives a general insight into the evolution of nanosciences and nanotechnologies. The reader is thus provided with an introduction to this complex area with different “tracks” for further personal comprehension and reflection. This guided and illustrated tour also reveals the importance of the nanoworld in everyday life.

An Introduction to Ministry is a comprehensive and ecumenical introduction to the craft of ministry for ministers, pastors, and priests that make up the mainline denominations in the United States. Ecumenically-focused, It offers a grounded account of ministry, covering areas such as vocation, congregational leadership, and cultivation of skills for an effective ministry. Covers the key components of the M.Div. curriculum, offering a map and guide to the central skills and issues in training Explores the areas of vocation, skills for ministry, and issues around congregational leadership Each topic ends with an annotated bibliography providing an indispensable gateway to further study Helps students understand both the distinctive approach of their denomination and the relationship of that approach to other mainline denominations Advocates and defends a generous understanding of the Christian tradition in its openness and commitment to broad conversation

Praise for the First Edition «. . . outstandingly appealing with regard to its style, contents, considerations of requirements of practice, choice of examples, and exercises.»—Zentralblatt MATH «. . . carefully structured with many detailed worked examples.»—The Mathematical Gazette The Second Edition of the highly regarded An Introduction to Numerical Methods and Analysis provides a fully revised guide to numerical approximation. The book continues to be accessible and expertly guides readers through the many available techniques of numerical methods and analysis. An Introduction to Numerical Methods and Analysis, Second Edition reflects the latest trends in the field, includes new material and revised exercises, and offers a unique emphasis on applications. The author clearly explains how to both construct and evaluate approximations for accuracy and performance, which are key skills in a variety of fields. A wide range of higher-level methods and solutions, including new topics such as the roots of polynomials, spectral collocation, finite element ideas, and Clenshaw-Curtis quadrature, are presented from an introductory perspective, and the Second Edition also features: Chapters and sections that begin with basic, elementary material followed by gradual coverage of more advanced material Exercises ranging from simple hand computations to challenging derivations and minor proofs to programming exercises Widespread exposure and utilization of MATLAB An appendix that contains proofs of various theorems and other material The book is an ideal textbook for students in advanced undergraduate mathematics and engineering courses who are interested in gaining an understanding of numerical methods and numerical analysis.

This new textbook is a lively and highly accessible introduction to philosophy. From the fundamental issues of philosophical thought to the latest theories in the philosophy of mind, An Introduction to Philosophy provides clear and incisive discussion of the key areas of philosophy for students new to the subject. Provides the tools new students need to tackle philosophical arguments themselves Clearly presents and explains contemporary issues and current debates Covers the key areas of philosophy, including perception, epistemology, metaphysics, the mind, philosophy of religion, ethics and political philosophy Contains numerous learning features such as introductions, summaries, questions and further reading An Introduction to Philosophy is an ideal text for AS level, A level and first-year undergraduate students or anyone studying the subject for the first time.

A modern, up-to-date introduction to optimization theory and methods This authoritative book serves as an introductory text to optimization at the senior undergraduate and beginning graduate levels. With consistently accessible and elementary treatment of all topics, An Introduction to Optimization, Second Edition helps students build a solid working knowledge of the field, including unconstrained optimization, linear programming, and constrained optimization. Supplemented with more than one hundred tables and illustrations, an extensive bibliography, and numerous worked examples to illustrate both theory and algorithms, this book also provides: * A review of the required mathematical background material * A mathematical discussion at a level accessible to MBA and business students * A treatment of both linear and nonlinear programming * An introduction to recent developments, including neural networks, genetic algorithms, and interior-point methods * A chapter on the use of descent algorithms for the training of feedforward neural networks * Exercise problems after every chapter, many new to this edition * MATLAB(r) exercises and examples * Accompanying Instructor's Solutions Manual available on request An Introduction to Optimization, Second Edition helps students prepare for the advanced topics and technological developments that lie ahead. It is also a useful book for researchers and professionals in mathematics, electrical engineering, economics, statistics, and business. An Instructor's Manual presenting detailed solutions to all the problems in the book is available from the Wiley editorial department.

The one-stop reference to the essentials of color science and technology—now fully updated and revised The fully updated Third Edition of Color: An Introduction to Practice and Principles continues to provide a truly comprehensive, non-mathematical introduction to color science, complete with historical, philosophical, and art-related topics. Geared to non-specialists and experts alike, Color clearly explains key technical concepts concerning light, human vision, and color perception phenomena. It covers color order systems in depth, examines color reproduction technologies, and reviews the history of color science as well as its relationship to art and color harmony. Revised throughout to reflect the latest developments in the field, the Third Edition: Features many new color illustrations, now fully incorporated into the text Offers new perspectives on what color is all about, diverging from conventional thinking Includes new information on perception phenomena, color order, and technological advances Updates material on such topics as the CIE colorimetric system and optimal object colors Extends coverage of color reproduction to display systems, photography, and color management Contains a unique timetable of color in science and art, plus a glossary of important terms Praise for the previous editions: «A nice bridge to areas usually not covered in academic visual science programs . . . outstanding.» —Joel Pokorny, visual scientist at The University of Chicago «A good addition to any library, this should be useful for the color interests of artists, designers, craftsmen, philosophers, psychologists, color technologies, and students in related fields.» —CHOICE

Praise from the Second Edition «…an excellent introduction to optimization theory…» (Journal of Mathematical Psychology, 2002) «A textbook for a one-semester course on optimization theory and methods at the senior undergraduate or beginning graduate level.» (SciTech Book News, Vol. 26, No. 2, June 2002) Explore the latest applications of optimization theory and methods Optimization is central to any problem involving decision making in many disciplines, such as engineering, mathematics, statistics, economics, and computer science. Now, more than ever, it is increasingly vital to have a firm grasp of the topic due to the rapid progress in computer technology, including the development and availability of user-friendly software, high-speed and parallel processors, and networks. Fully updated to reflect modern developments in the field, An Introduction to Optimization, Third Edition fills the need for an accessible, yet rigorous, introduction to optimization theory and methods. The book begins with a review of basic definitions and notations and also provides the related fundamental background of linear algebra, geometry, and calculus. With this foundation, the authors explore the essential topics of unconstrained optimization problems, linear programming problems, and nonlinear constrained optimization. An optimization perspective on global search methods is featured and includes discussions on genetic algorithms, particle swarm optimization, and the simulated annealing algorithm. In addition, the book includes an elementary introduction to artificial neural networks, convex optimization, and multi-objective optimization, all of which are of tremendous interest to students, researchers, and practitioners. Additional features of the Third Edition include: New discussions of semidefinite programming and Lagrangian algorithms A new chapter on global search methods A new chapter on multipleobjective optimization New and modified examples and exercises in each chapter as well as an updated bibliography containing new references An updated Instructor's Manual with fully worked-out solutions to the exercises Numerous diagrams and figures found throughout the text complement the written presentation of key concepts, and each chapter is followed by MATLAB exercises and drill problems that reinforce the discussed theory and algorithms. With innovative coverage and a straightforward approach, An Introduction to Optimization, Third Edition is an excellent book for courses in optimization theory and methods at the upper-undergraduate and graduate levels. It also serves as a useful, self-contained reference for researchers and professionals in a wide array of fields.

Introduces readers to the field of cyber modeling and simulation and examines current developments in the US and internationally This book provides an overview of cyber modeling and simulation (M&S) developments. Using scenarios, courses of action (COAs), and current M&S and simulation environments, the author presents the overall information assurance process, incorporating the people, policies, processes, and technologies currently available in the field. The author ties up the various threads that currently compose cyber M&S into a coherent view of what is measurable, simulative, and usable in order to evaluate systems for assured operation. An Introduction to Cyber Modeling and Simulation provides the reader with examples of tools and technologies currently available for performing cyber modeling and simulation. It examines how decision-making processes may benefit from M&S in cyber defense. It also examines example emulators, simulators and their potential combination. The book also takes a look at corresponding verification and validation (V&V) processes, which provide the operational community with confidence in knowing that cyber models represent the real world. This book: Explores the role of cyber M&S in decision making Provides a method for contextualizing and understanding cyber risk Shows how concepts such the Risk Management Framework (RMF) leverage multiple processes and policies into a coherent whole Evaluates standards for pure IT operations, «cyber for cyber,» and operational/mission cyber evaluations—"cyber for others" Develops a method for estimating both the vulnerability of the system (i.e., time to exploit) and provides an approach for mitigating risk via policy, training, and technology alternatives Uses a model-based approach An Introduction to Cyber Modeling and Simulation is a must read for all technical professionals and students wishing to expand their knowledge of cyber M&S for future professional work.