Atlas of Comparative Diagnostic and Experimental Hematology

This new edition of Handbook of Pediatric Hematology and Oncology: Children's Hospital & Research Center Oakland features practical guidance on how to handle common inpatient and outpatient challenges seen in pediatric hematology and oncology. Designed as a rapid reference to the latest diagnostic and therapeutic protocols, the text is short and didactic and supplemented with practical algorithms and case studies throughout. Completely revised and updated, there are brand-new chapters on subjects including bone marrow transplantation, pain management and palliative care. Comprehensive, yet concise, the handbook presents essential guidelines on the diagnosis and management of the most common pediatric blood disorders and malignancies, in addition to chemotherapeutic drug information and transfusion protocols. Designed for medical students, residents, and fellows, this user-friendly portable reference is also the perfect companion on the ward for pediatric hematology and oncology nurses.

Veterinary Hematology and Clinical Chemistry, Second Edition is a well-illustrated, user-friendly reference on veterinary laboratory diagnostic techniques and interpretation. Covering both hematology and chemistry for a wide range of species, including birds, reptiles, amphibians, and fish, the book provides an overview of these critical veterinary skills. This Second Edition includes many revisions and additions, including new chapters on molecular diagnostics of hematologic malignancies and lipid pathology, updates to reflect advances in diagnostic instrumentation and capabilities, significant revisions to the data interpretation chapter to provide introductory guidance, and current information on immunodiagnostics and laboratory diagnostics of renal, endocrine, and calcium metabolic pathologies. Beginning with the basic principles of laboratory testing and diagnosis, the book moves into in-depth information on hematology and chemistry of common domestic and non-domestic species. Clinical case presentations, supplying case data and offering narrative discussions to promote skills, have been expanded and incorporated into the body of the book. Packed with useful information for veterinary students, technicians, pathologists, and researchers, Veterinary Hematology and Clinical Chemistry is an essential addition to any veterinary library.

Exotic Animal Hematology and Cytology, Fourth Edition updates the most comprehensive reference available on exotic animal hematology and cytology of all major species. Acts as both an atlas and a text, offering high-quality photographs and step-by-step descriptions of techniques associated with preparing and interpreting hematology and cytology samples Presents complete information on hematology and cytology in a wide range of exotic species, including small mammals, birds, reptiles, amphibians, and fish Includes more than 700 high-quality color photographs, now with sizing bars Takes a new disease-based structure for improved ease of use Provides straightforward step-by-step descriptions of sample preparation and interpretation

Thoroughly and systematically presents the state-of-the-art in the diagnostic uses of radiologic imaging and nuclear medicine in the diagnosis and management of infectious and inflammatory diseases Although our understanding of microorganisms has advanced significantly and antimicrobial therapy has become increasingly available, infection remains a major cause of patient morbidity and mortality. Imaging of infection and inflammation provides a classic example of radiology and nuclear medicine’s strengths as well as weaknesses in the discovery and diagnosis of disease. Fortunately, the weaknesses are subsiding as new studies and techniques point to better planning and precision in the use of single and combined imaging modalities. Diagnostic Imaging of Infections and Inflammatory Diseases: A Multidisciplinary Approach deals with the very latest developments in the use of radiologic techniques and modalities in the management of patients with a host of infectious and inflammatory diseases. Tremendously timely and useful, this innovative, multidisciplinary book covers a wide range of topics in three parts: PART 1: Infections and Host Response Epidemiology of Infections in the New Century Bacterial Osteomyelitis: the Clinician Point of View PART 2: Radiological Imaging Radiological Imaging of Osteomyelitis Radiological Imaging of Spine Infection Radiological Imaging of Soft Tissue Infections Radiological Imaging of Abdominal Infections and Inflammatory Disease Radiological Imaging of Vascular Graft Infection Radiological Imaging of TB and HIV PART 3: Nuclear Medicine Imaging Nuclear Medicine Imaging of Infections: Techniques, Acquisition Protocols, and Interpretation Criteria Nuclear Medicine Imaging of Osteomyelitis: WBC, Monoclonal Antibody, or Bacterial Imaging? Nuclear Medicine Imaging of Spondylodiscitis: The Emerging Role of PET Nuclear Medicine Imaging of Soft Tissue Infections Nuclear Medicine Imaging of Infections and Inflammatory Diseases of the Abdomen Nuclear Medicine Imaging of Vascular Graft Infections: The Added Role of Hybrid Imaging Nuclear Medicine Imaging of TB and HIV Nuclear Medicine Imaging of Fever of Unknown Origin Nuclear Medicine Imaging of Inflammatory Diseases Along with carefully developed clinical cases describing the management of patients with inflammation and infection, Diagnostic Imaging of Infections and Inflammatory Diseases is an ideal guide for radiologists and nuclear medicine physicians as well as clinical specialists from many other fields.

From the characterization of materials to accelerated life testing, experimentation with solids and structures is present in all stages of the design of mechanical devices. Sometimes only an experimental model can bring the necessary elements for understanding, the physics under study just being too complex for an efficient numerical model. This book presents the classical tools in the experimental approach to mechanical engineering, as well as the methods that have revolutionized the field over the past 20 years: photomechanics, signal processing, statistical data analysis, design of experiments, uncertainty analysis, etc. Experimental Mechanics of Solids and Structures also replaces mechanical testing in a larger context: firstly, that of the experimental model, with its own hypotheses; then that of the knowledge acquisition process, which is structured and robust; finally, that of a reliable analysis of the results obtained, in a context where uncertainty could be important.

The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Cyclooxygenases (COXs) are enzymes responsible for the formation of an important class of biological mediators called prostanoids. Prostanoids such as prostaglandins mediate inflammatory and anaphylactic reactions. For those suffering from inflammation and pain, the pharmacological inhibition of COXs, with non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, can provide relief. Yet the use of NSAIDs can trigger toxicological effects as well, leading to potential health risks. Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited. The book provides an introduction to the discovery of cyclooxygenases, their use as therapeutic agents, as well as an historical perspective. Shedding light on the differences in expression, pathophysiology, and toxicology of COX inhibitors across species, the book offers a systematic examination of the effects and pathophysiology of COX inhibitors and their mechanisms of toxicity, beginning with the GI tract. Subsequent chapters cover: The pathophysiology of COX inhibition on bone, tendon, and ligament healing COX inhibitors and renal system pathophysiology and mechanisms of toxicity The pathophysiologic role of COX inhibition in the ocular system COX inhibition and the respiratory and cardiovascular systems The book also sheds light on the latest research devoted to developing COX inhibitors with no adverse side-effects. The first book to offer a thorough comparative look at the toxicological effects of COX inhibitors throughout the body, this invaluable resource will help advance the research and development of safer and more effective COX drugs.

Wish you could interpret cytological specimens in practice rather than paying a lab to do it for you? Want to provide your clients with a faster service? Manual of Diagnostic Cytology of the Dog and Cat is the ideal quick reference for the busy veterinarian in first opinion practice. It describes techniques for obtaining good quality cytological diagnostic specimens, and guides you through the interpretation of cytological findings. Created to be used alongside the microscope, hundreds of high quality colour photos will help you to identify normal cell types and abnormal cytology, including both non-neoplastic and neoplastic lesions. It describes in a clear and concise manner the most common lesions and related disorders encountered in a practice setting. The concise format means that you can quickly find exactly what you’re looking for. Covering indications for cytological investigation, collection techniques and the evaluation and interpretation of findings, this concise manual will be your go-to resource.

Professionals in all areas – business; government; the physical, life, and social sciences; engineering; medicine, etc. – benefit from using statistical experimental design to better understand their worlds and then use that understanding to improve the products, processes, and programs they are responsible for. This book aims to provide the practitioners of tomorrow with a memorable, easy to read, engaging guide to statistics and experimental design. This book uses examples, drawn from a variety of established texts, and embeds them in a business or scientific context, seasoned with a dash of humor, to emphasize the issues and ideas that led to the experiment and the what-do-we-do-next? steps after the experiment. Graphical data displays are emphasized as means of discovery and communication and formulas are minimized, with a focus on interpreting the results that software produce. The role of subject-matter knowledge, and passion, is also illustrated. The examples do not require specialized knowledge, and the lessons they contain are transferrable to other contexts. Fundamentals of Statistical Experimental Design and Analysis introduces the basic elements of an experimental design, and the basic concepts underlying statistical analyses. Subsequent chapters address the following families of experimental designs: Completely Randomized designs, with single or multiple treatment factors, quantitative or qualitative Randomized Block designs Latin Square designs Split-Unit designs Repeated Measures designs Robust designs Optimal designs Written in an accessible, student-friendly style, this book is suitable for a general audience and particularly for those professionals seeking to improve and apply their understanding of experimental design.

Now available in paperback. This revised and updated edition of the definitive resource for experimental psychology offers comprehensive coverage of the latest findings in the field, as well as the most recent contributions in methodology and the explosion of research in neuroscience. Volume One: Sensation and Perception focuses on sensory experience and complex learned perceptions through modalities such as vision, touch, smell, and hearing.