Discovering the Future of Molecular Sciences

Molecular imaging is primarily about the chemistry of novel biological probes, yet the vast majority of practitioners are not chemists or biochemists. This is the first book, written from a chemist's point of view, to address the nature of the chemical interaction between probe and environment to help elucidate biochemical detail instead of bulk anatomy. Covers all of the fundamentals of modern imaging methodologies, including their techniques and application within medicine and industry Focuses primarily on the chemistry of probes and imaging agents, and chemical methodology for labelling and bioconjugation First book to investigate the chemistry of molecular imaging Aimed at students as well as researchers involved in the area of molecular imaging

This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review Supported by a dedicated website at www.blackwellpublishing.com/pelengaris An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field

The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. “Bench to Bedside”: A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients – essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: An overview of the cancer cell and important new concepts. Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. Chapters highlighting the direct links between cancer research and clinical applications. New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. Quotations have been used in each chapter to introduce basic concepts in an entertaining way. Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: “A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology…..This book deserves great praise for the readable presentation of this complex field….the true synthesis of bench and bedside approaches is marvelously achieved.” Christian Schmidt, Molecular Cell “Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references….This book is applicable to both graduate and undergraduate students, and in the context of a

The Sciences of Animal Welfare analyses the diverse, interconnecting subjects which constitute this fascinating multidisciplinary field, whilst also considering the limitations and benefits of those subjects to the development and future of Animal Welfare Science. This book examines past, present and future practices and thinking, including the wide-ranging interests within society that influence attitudes towards animals and conversely how animal welfare scientists may influence those attitudes. Key themes of the book include: • Multi-disciplinary working and its benefits: how we can obtain fresh insights, enliven our thinking and improve animal welfare by operating widely within diverse disciplines • Questioning the fundamental assumptions we each make about animals and their functional capabilities. The authors acknowledge the field’s debt to past successes in animal-based science disciplines, successes that markedly improved animal welfare long before the concept of animal welfare entered common parlance. They also recognise the problems which unexpectedly arose, and anticipate future successes. Suggesting innovative approaches to Animal Welfare Science, and written by world renowned experts, The Sciences of Animal Welfare is essential reading for anyone interested, studying or currently working in Animal Welfare Science. This book is part of the UFAW/Wiley-Blackwell Animal Welfare Book Series. This major series of books produced in collaboration between UFAW (The Universities Federation for Animal Welfare), and Wiley-Blackwell provides an authoritative source of information on worldwide developments, current thinking and best practice in the field of animal welfare science and technology. For details of all of the titles in the series see www.wiley.com/go/ufaw.

The allocation of limited public and private resources depends on reliable data and empirical analysis, and The Future of Philanthropy is filled with hard-to-find data, graphs, and charts, as well as full citation and source lists at the end of each chapter. It raises unsettling questions about the very assumptions upon which nonprofits are built and financed and about the future of nonprofit and philanthropic decision-making. Written to provoke thoughtful debate, as well as illuminate elusive objective data, this resource also sheds new light on the challenges that face the nation’s «Third Sector» as public and governmental regulation has become more focused on the transparency and accountability of philanthropy and its recipients. Order your copy today!

In this book, Professor Christopher Coker presents an original and controversial thesis about the future of war. Argues that the biotechnology revolution has given war a new lease of life. Draws on thinkers from Hegel and Nietzsche to the postmodernists. Refers to modern fiction and films. Part of the prestigious Blackwell Manifestos series.

In this controversial manifesto, Jean-Michel Rabat? addresses current anxieties about the future of literary and cultural theory and proposes that it still has a crucial role to play.

The field of lymphokine research has grown in parallel to the exciting developments around the two sets of cells which defend the body. While lymphokines are the «property» of immunologists, the molecular regulators of hemopoiesis (CSFs) belong to the hematologists. This book offers the rare opportunity to examine these separate fields of expertise together.

This important Manifesto argues that we still need a concept of society in order to make sense of the forces which structure our lives. Written by leading social theorist William Outhwaite Asks if the notion of society is relevant in the twenty-first century Goes to the heart of contemporary social and political debate Examines critiques of the concept of society from neoliberals, postmodernists, and globalization theorists

This key work addresses one of the most central and controversial issues in contemporary feminist theory: the problem of difference.