Drug Utilization Research

Providing the latest information on preventive, diagnostic and therapeutic aspects of tuberculosis and AIDS, this is the only book to place a major emphasis on the increasing coexistence of these two life-threatening diseases in individuals. Edited by outstanding scientists in the field, this ready reference is divided into three main sections covering immunology and vaccination strategies, drugs, and clinical issues. Timely reading for microbiologists, virologists, bacteriologists, immunologists, and pathophysiologists, as well as for the pharmaceutical and biotechnological industries.

Rapid Infectious Diseases is the fourth book to appear in the Rapid series. Each book is designed for short revision covering key facts in a simple and memorable fashion, using well-thought out mnemonics to aid recall This new text provides students in the run-up to exams with a comprehensive review of possible causes for symptoms and conditions as well as the key facts of around 100 diseases, following the Rapid mnemonic. There will also be an appendix giving details of immunisations as well as a list of Further Reading and useful web sites. Clinical students working on Emergency Medicine and General Practice attachments will find this book extremely useful. It may also interest those planning electives abroad. Junior doctors and GPs will find this a handy resource for quick access to information on the symptoms and diseases they may encounter in the clinical setting.

Continuing accumulation of scientific evidence demonstrates that nutrition is one of the most important determinants of health for the individual, and that specific nutrition habits of various populations can significantly decrease the overall risk of several chronic diseases. This landmark publication, which contains papers presented at the 1st Nutrition and Health conference, covers the major topics relating to nutritional aspects of health. Chapters within this important book cover vital health issues, including details of the links between diet and cardiovascular disease, obesity, cancer, diabetes and osteoporosis. Further chapters within Nutrition and Health cover important nutritional issues, for example managing the human gut flora, vegetarianism and the role of phytoprotectants. Each chapter has been written by a well-known expert, and the whole has been drawn together and carefully edited, providing an important reference resource for the future. All health professionals interested or involved in nutrition and the impact of nutrition on health should have a copy of this book on their shelves, as should libraries in all medical schools, and universities and research establishments where nutrition, dietetics and food science are studied and taught. Also available from Blackwell Publishing A major series of textbooks from the Nutrition Society Introduction to Human Nutrition (0 632 05624 X) Nutrition and Metabolism (0 632 05625 8) Clinical Nutrition (0 632 05626 6) Public Health Nutrition (0 632 05627 4) Nutrition Bulletin (Journal) Published quarterly ISSN: 0141 9684 Adverse Reactions to Foods Edited by J. Buttriss (BNF) 0 632 055472 Principles of Human Nutrition Second edition M. Eastwood 0 632 05811 0

ExpDesign Studio facilitates more efficient clinical trial design This book introduces pharmaceutical statisticians, scientists, researchers, and others to ExpDesign Studio software for classical and adaptive designs of clinical trials. It includes the Professional Version 5.0 of ExpDesign Studio software that frees pharmaceutical professionals to focus on drug development and related challenges while the software handles the essential calculations and computations. After a hands-on introduction to the software and an overview of clinical trial designs encompassing numerous variations, Classical and Adaptive Clinical Trial Designs Using ExpDesign Studio: Covers both classical and adaptive clinical trial designs, monitoring, and analyses Explains various classical and adaptive designs including groupsequential, sample-size reestimation, dropping-loser, biomarker-adaptive, and response-adaptive randomization designs Includes instructions for over 100 design methods that have been implemented in ExpDesign Studio and step-by-step demos as well as real-world examples Emphasizes applications, yet covers key mathematical formulations Introduces readers to additional toolkits in ExpDesign Studio that help in designing, monitoring, and analyzing trials, such as the adaptive monitor, graphical calculator, the probability calculator, the confidence interval calculator, and more Presents comprehensive technique notes for sample-size calculation methods, grouped by the number of arms, the trial endpoint, and the analysis basis Written with practitioners in mind, this is an ideal self-study guide for not only statisticians, but also scientists, researchers, and professionals in the pharmaceutical industry, contract research organizations (CROs), and regulatory bodies. It's also a go-to reference for biostatisticians, pharmacokinetic specialists, and principal investigators involved in clinical trials. ERRATUM Classical and Adaptive Clinical Trial Designs Using ExpDesign Studio By Mark Chang The license for the ExpDesign Studio software on the CD included with this book is good for one-year after installation of the software. Prior to the expiration of this period, the software will generate a reminder about renewal for the license. The user should contact CTriSoft International (the owners of ExpDesign Studio) at www.CTriSoft.net or by email at license@ctrisoft.net, about renewal for the license. This should have been made clear in the first printing of this book. We apologize for this error.

This book provides a step-by-step guide to understanding and treating psychogenic voice disorder by combining speech and language therapy with skills drawn from the field of cognitive behaviour therapy (CBT). Beginning with a new classification of psychogenic voice disorder, the authors then provide a description of the CBT model and give helpful and systematic guidelines on using this approach in combination with speech and language therapy skills. They provide invaluable guidance on how to extend the standard voice case history to include a psychosocial assessment, and how to apply symptomatic voice therapy principles and techniques for this patient population. Later chapters show how to assess and work with patients suffering from symptoms of anxiety and lowered mood, and how to understand and respond to various forms of psychopathology that may present in association with voice disorder. Finally, detailed case studies illustrate how an experienced therapist might respond to individual assessment and treatment challenges.