Emotion-Oriented Systems

Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

A thorough knowledge of modern connection-oriented networks is essential to understanding the current and near-future state of networking. This book provides a complete overview of connection-oriented networks, discussing both packet-switched and circuit-switched networks, which, though seemingly different, share common networking principles. It details the history and development of such networks, and defines their terminology and architecture, before progressing to aspects such as signaling and standards. There is inclusive coverage of SONET/SDH, ATM networks, Multi-Protocol Label Switching (MPLS), optical networks, access networks and voice over ATM and MPLS. Connection-oriented Networks: * Provides in-depth, systematic coverage of several connection-oriented networks in a single volume * Explains topics such as the Generic Framing Procedure, Label Distribution Protocols, Wavelength Routing Optical Networks, Optical Burst Switching, and Access Networks in detail * Illustrates all concepts with problems and simulation projects to test and deepen your understanding * Includes an accompanying website with solutions manual and complete set of PowerPoint presentations for each chapter Senior undergraduate and graduate students in telecommunication and networking courses, as well as networking engineers, will find this comprehensive guide to connection-oriented packet-switched and circuit-switched networks useful for their training. The book presents tried and tested material based on an existing, successful course.

Component Oriented Programming offers a unique programming-centered approach to component-based software development that delivers the well-developed training and practices you need to successfully apply this cost-effective method. Following an overview of basic theories and methodologies, the authors provide a unified component infrastructure for building component software using JavaBeans, EJB, OSGi, CORBA, CCM, .NET, and Web services. You'll learn how to develop reusable software components; build a software system of pre-built software components; design and implement a component-based software system using various component-based approaches. Clear organization and self-testing features make Component Oriented Programming an ideal textbook for graduate and undergraduate courses in computer science, software engineering, or information technology as well as a valuable reference for industry professionals.

This comprehensive text explains the principles and practice of Web services and relates all concepts to practical examples and emerging standards. Its discussions include: Ontologies Semantic web technologies Peer-to-peer service discovery Service selection Web structure and link analysis Distributed transactions Process modelling Consistency management. The application of these technologies is clearly explained within the context of planning, negotiation, contracts, compliance, privacy, and network policies. The presentation of the intellectual underpinnings of Web services draws from several key disciplines such as databases, distributed computing, artificial intelligence, and multi-agent systems for techniques and formalisms. Ideas from these disciplines are united in the context of Web services and service-based applications. Featuring an accompanying website and teacher’s manual that includes a complete set of transparencies for lectures, copies of open-source software for exercises and working implementations, and resources to conduct course projects, this book makes an excellent graduate textbook. It will also prove an invaluable reference and training tool for practitioners.

Meets the need for a program of short courses involving the essentials of a number of mathematical topics taken by physics and engineering students. Basically applications-oriented, the courses do include selected topics of abstract mathematics. While several courses can be used as practical appendices to conventional mathematics, others serve as introductions, providing motivation for self-study in areas of conceptual math.

The first single-source reference covering the state of the art in grid and utility computing economy research This book presents the first integrated, single-source reference on market-oriented grid and utility computing. Divided into four main parts—and with contributions from a panel of experts in the field—it systematically and carefully explores: Foundations—presents the fundamental concepts of market-oriented computing and the issues and challenges in allocating resources in a decentralized computing environment. Business models—covers business models for service providers and brokers supporting different types of distributed applications, as well as business rules-based models for managing virtual organizations and accounting operations and services in grid computing environments. Policies and agreements—introduces policies, agreements, and specifications for the negotiation and establishment of contracts between providers and consumers. It also covers different approaches for resource allocation based on service-level agreements (SLAs) and management of risks associated with SLA violations. Resource allocation and scheduling mechanisms—covers economic models, such as commodity models, reciprocation, auctions, and game theory, and middleware technologies, such as Nimrod/G and Gridbus, for market-oriented grid computing and utility-oriented resource allocation. This book expertly captures the state of the art in the field while also identifying potential research directions and technologies that will facilitate the creation of global commercial grid and utility computing systems. It is an indispensable reference for systems architects, practitioners, developers, new researchers, and graduate students.

In recent years, the systems designed to support activity in the fields of banking, health, transportation, space, aeronautics, defense, etc. have become increasingly larger and more complex. With the growing maturity of information and communication technologies, systems have been interconnected within growing networks, yielding new capabilities and services through the combination of system functionalities. This has led to a further increasing complexity that has to be managed in order to take advantage of these system integrations. The book is divided into two parts. The first part addresses the concept and practical illustrations of a “system of systems” and is a multidisciplinary introduction to the notion of a “systems of systems” that is discussed extensively in the current scientific and technical literature. After a critical comparison of the different definitions and a range of various practical illustrations, this part provides answers to key questions such as what a system of systems is and how its complexity can be mastered. The second part, described as “systems-of-systems engineering: methods and tools”, focuses on both engineering and modeling, and standardization issues that are critical to deal with the key steps in systems of systems engineering: namely eliciting stakeholder needs, architecture optimization, integration of constituent systems, qualification, and utilization.

Trustworthiness technologies and systems for service-oriented environments are re-shaping the world of e-business. By building trust relationships and establishing trustworthiness and reputation ratings, service providers and organizations will improve customer service, business value and consumer confidence, and provide quality assessment and assurance for the customer in the networked economy. Trust and Reputation for Service-Oriented Environments is a complete tutorial on how to provide business intelligence for sellers, service providers, and manufacturers. In an accessible style, the authors show how the capture of consumer requirements and end-user opinions gives modern businesses the competitive advantage. Trust and Reputation for Service-Oriented Environments: Clarifies trust and security concepts, and defines trust, trust relationships, trustworthiness, reputation, reputation relationships, and trust and reputation models. Details trust and reputation ontologies and databases. Explores the dynamic nature of trust and reputation and how to manage them efficiently. Provides methodologies for trustworthiness measurement, reputation assessment and trustworthiness prediction. Evaluates current trust and reputation systems as employed by companies such as Yahoo, eBay, BizRate, Epinion and Amazon, etc. Gives ample illustrations and real world examples to help validate trust and reputation concepts and methodologies. Offers an accompanying website with lecture notes and PowerPoint slides. This text will give senior undergraduate and masters level students of IT, IS, computer science, computer engineering and business disciplines a full understanding of the concepts and issues involved in trust and reputation. Business providers, consumer watch-dogs and government organizations will find it an invaluable reference to establishing and maintaining trust in open, distributed, anonymous service-oriented network environments.