Enzyme-Based Computing Systems

Discover the science of biocomputing with this comprehensive and forward-looking new resource DNA- and RNA-Based Computing Systems delivers an authoritative overview of DNA- and RNA-based biocomputing systems that touches on cutting-edge advancements in computer science, biotechnology, nanotechnology, and materials science. Accomplished researcher, academic, and author Evgeny Katz offers readers an examination of the intersection of computational, chemical, materials, and engineering aspects of biomolecular information processing. A perfect companion to the recently published Enzyme-Based Computing by the same editor, the book is an authoritative reference for those who hope to better understand DNA- and RNA-based logic gates, multi-component logic networks, combinatorial calculators, and related computational systems that have recently been developed for use in biocomputing devices. DNA- and RNA-Based Computing Systems summarizes the latest research efforts in this rapidly evolving field and points to possible future research foci. Along with an examination of potential applications in biosensing and bioactuation, particularly in the field of biomedicine, the book also includes topics like: A thorough introduction to the fields of DNA and RNA computing, including DNA/enzyme circuits A description of DNA logic gates, switches and circuits, and how to program them An introduction to photonic logic using DNA and RNA The development and applications of DNA computing for use in databases and robotics Perfect for biochemists, biotechnologists, materials scientists, and bioengineers, DNA- and RNA-Based Computing Systems also belongs on the bookshelves of computer technologists and electrical engineers who seek to improve their understanding of biomolecular information processing. Senior undergraduate students and graduate students in biochemistry, materials science, and computer science will also benefit from this book.

Enzyme-Based Organic Synthesis An insightful exploration of an increasingly popular technique in organic chemistry In Enzyme-Based Organic Synthesis , expert chemist Dr. Cheanyeh Cheng delivers a comprehensive discussion of the principles, methods, and applications of enzymatic and microbial processes for organic synthesis. The book thoroughly explores this growing area of green synthetic organic chemistry, both in the context of academic research and industrial practice. The distinguished author provides a single point of access for enzymatic methods applicable to organic synthesis and focuses on enzyme catalyzed organic synthesis with six different classes of enzyme. This book serves as a link between enzymology and biocatalysis and serves as an invaluable reference for the growing number of organic chemists using biocatalysis. Enzyme-Based Organic Synthesis provides readers with multiple examples of practical applications of the main enzyme classes relevant to the pharmaceutical, medical, food, cosmetics, fragrance, and health care industries. Readers will also find: A thorough introduction to foundational topics, including the discovery and nature of enzymes, enzyme structure, catalytic function, molecular recognition, enzyme specificity, and enzyme classes Practical discussions of organic synthesis with oxidoreductases, including oxidation reactions and reduction reactions Comprehensive explorations of organic synthesis with transferases, including transamination with aminotransferases and phosphorylation with kinases In-depth examinations of organic synthesis with hydrolases, including the hydrolysis of the ester bond Perfect for organic synthetic chemists, chemical and biochemical engineers, biotechnologists, process chemists, and enzymologists, Enzyme-Based Organic Synthesis is also an indispensable resource for practitioners in the pharmaceutical, food, cosmetics, and fragrance industries that regularly apply this type of synthesis.

The energy consumption issue in distributed computing systems raises various monetary, environmental and system performance concerns. Electricity consumption in the US doubled from 2000 to 2005. From a financial and environmental standpoint, reducing the consumption of electricity is important, yet these reforms must not lead to performance degradation of the computing systems. These contradicting constraints create a suite of complex problems that need to be resolved in order to lead to 'greener' distributed computing systems. This book brings together a group of outstanding researchers that investigate the different facets of green and energy efficient distributed computing. Key features: One of the first books of its kind Features latest research findings on emerging topics by well-known scientists Valuable research for grad students, postdocs, and researchers Research will greatly feed into other technologies and application domains

This is the first practical treatment of the design and application of feedback control of computing systems. MATLAB files for the solution of problems and case studies accompany the text throughout. The book discusses information technology examples, such as maximizing the efficiency of Lotus Notes. This book results from the authors' research into the use of control theory to model and control computing systems. This has important implications to the way engineers and researchers approach different resource management problems. This guide is well suited for professionals and researchers in information technology and computer science.

This book is a contribution to the definition of a model based system engineering (MBSE) approach, designed to meet the objectives laid out by the INCOSE. After pointing out the complexity that jeopardizes a lot of system developments, the book examines fundamental aspects of systems under consideration. It goes on to address methodological issues and proposes a methodic approach of MBSE that provides, unlike current practices, systematic and integrated model-based engineering processes. An annex describes relevant features of the VHDL-AMS language supporting the methodological issues described in the book.

Neuromorphic electronic engineering takes its inspiration from the functioning of nervous systems to build more power efficient electronic sensors and processors. Event-based neuromorphic systems are inspired by the brain's efficient data-driven communication design, which is key to its quick responses and remarkable capabilities. This cross-disciplinary text establishes how circuit building blocks are combined in architectures to construct complete systems. These include vision and auditory sensors as well as neuronal processing and learning circuits that implement models of nervous systems. Techniques for building multi-chip scalable systems are considered throughout the book, including methods for dealing with transistor mismatch, extensive discussions of communication and interfacing, and making systems that operate in the real world. The book also provides historical context that helps relate the architectures and circuits to each other and that guides readers to the extensive literature. Chapters are written by founding experts and have been extensively edited for overall coherence. This pioneering text is an indispensable resource for practicing neuromorphic electronic engineers, advanced electrical engineering and computer science students and researchers interested in neuromorphic systems. Key features: Summarises the latest design approaches, applications, and future challenges in the field of neuromorphic engineering. Presents examples of practical applications of neuromorphic design principles. Covers address-event communication, retinas, cochleas, locomotion, learning theory, neurons, synapses, floating gate circuits, hardware and software infrastructure, algorithms, and future challenges.

Programming multi-core and many-core computing systems Sabri Pllana, Linnaeus University, Sweden Fatos Xhafa, Technical University of Catalonia, Spain Provides state-of-the-art methods for programming multi-core and many-core systems The book comprises a selection of twenty two chapters covering: fundamental techniques and algorithms; programming approaches; methodologies and frameworks; scheduling and management; testing and evaluation methodologies; and case studies for programming multi-core and many-core systems. Program development for multi-core processors, especially for heterogeneous multi-core processors, is significantly more complex than for single-core processors. However, programmers have been traditionally trained for the development of sequential programs, and only a small percentage of them have experience with parallel programming. In the past, only a relatively small group of programmers interested in High Performance Computing (HPC) was concerned with the parallel programming issues, but the situation has changed dramatically with the appearance of multi-core processors on commonly used computing systems. It is expected that with the pervasiveness of multi-core processors, parallel programming will become mainstream. The pervasiveness of multi-core processors affects a large spectrum of systems, from embedded and general-purpose, to high-end computing systems. This book assists programmers in mastering the efficient programming of multi-core systems, which is of paramount importance for the software-intensive industry towards a more effective product-development cycle. Key features: Lessons, challenges, and roadmaps ahead. Contains real world examples and case studies. Helps programmers in mastering the efficient programming of multi-core and many-core systems. The book serves as a reference for a larger audience of practitioners, young researchers and graduate level students. A basic level of programming knowledge is required to use this book.

Enables readers to master and apply the operator-theoretic approach Control of nonlinear systems is a multidisciplinary field involving electrical engineering, computer science, and control engineering. Specifically, this book addresses uncertain nonlinearity. Beginning with how real plants are modeled as operator-based plants, the author develops a systematic methodology that enables readers to understand a quantitative stability result, a critical factor in any nonlinear control system's stability and performance. Operator-Based Nonlinear Control Systems: Design and Applications focuses on the operator-theoretic approach, offering detailed examples on how to apply it to network controlled systems. In addition to current research results, the author explores future research directions and applications of the operator-theoretic approach. The book begins with an introduction that defines nonlinear systems. Next, it covers: Robust right coprime factorization for nonlinear plants with uncertainties Robust stability of operator-based nonlinear control systems Tracking issues and fault detection issues in nonlinear control systems Operator-based nonlinear control systems with smart actuators Nonlinear feedback control for large-scale systems using a distributed control system device Throughout the book, discussions of actual applications help readers understand how the operator-theoretic approach works in practice. Operator-Based Nonlinear Control Systems is recommended for students and professionals in control theory engineering and applied mathematics. Working with this expertly written and organized book, they will learn how to obtain robust right coprime factorization for modeled plants. Moreover, they will discover state-of-the-technology research results on robust stability conditions as well as the latest system output tracking and fault detection issues that are challenging today's researchers.