Expert Report Writing in Toxicology. Forensic, Scientific and Legal Aspects

Practices associated with the culture of “scholarly” reading have been developed over many centuries and annotations themselves have become the subject of study, either as additional elements in connection with the original texts or as documents in their own right. The first “scholarly” reading techniques, seen historically from the 12th Century onwards, combine reading and writing in a process known as lettrure, involving both attentive reading and commentary. The Internet has transformed this activity, adding technical layers that relate both to the reading and writing process as well as to the circulation of texts; their potential and effective augmentation, diffusion, and reception. This book examines digitized reading and writing by focusing primarily on the conditions for the co-construction of scientific knowledge and its augmentation. The authors present numerous examples of studies and personal feedback concerning the intellectual process, open critical spaces, collaborative scholarly publishing, methods for the circulation and mediatization of knowledge, as well as the techniques and tools employed.

Practical and jargon-free, this book is aimed at the non-lawyer and includes an extensive glossary of terms. It emphasises the legal issues encountered by those working in diagnostic radiography, radiotherapy and radiology and includes examples of legal dilemmas taken from these disciplines as well as exploring current issues.

During the past decade it has become evident that microRNAs regulate gene expressions and control many developmental and cellular processes in eukaryotic organisms. Recent studies suggest that microRNAs play an important role in toxicogenomics and are likely to play an important role in a range of human diseases including cancer. microRNAs in Toxicology and Medicine is a comprehensive and authoritative compilation of up-to-date developments in this emerging research area, presented by internationally recognized investigators. It focuses on the role of microRNA in biology and medicine with a special emphasis on toxicology. Divided into six parts, topics covered include: microRNA and toxicology – including environmental toxicants and perturbation of miRNA signaling; microRNA, and Disease States featuring microRNAs in drug-induced liver toxicity, microRNAs and Inflammation the regulatory role of microRNA in mutagenesis, microRNAs and cancer, and the role of microRNAs in tumor progression and therapy, as well as current understanding of microRNAs as therapeutic targets in cancer microRNAs and disease states microRNAs and stem cells microRNAs and genomics microRNAs and epigenomics microRNAs and biomarkers – including body fluid microRNAs as toxicological biomarkers, cell-free microRNAs as biomarkers in human diseases, and circulating microRNAs as biomarkers of drug-induced pancreatitis microRNAs in Toxicology and Medicine is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors, and regulators in academia, medical settings, industry, and government.

A comprehensive and authoritative compilation of up-to-date developments in stem cell research and its use in toxicology and medicine Presented by internationally recognized investigators in this exciting field of scientific research Provides an insight into the current trends and future directions of research in this rapidly developing new field A valuable and excellent source of authoritative and up-to-date information for researchers, toxicologists, drug industry, risk assessors and regulators in academia, industry and government

This book shows scientists how to apply their analysis and synthesis skills to overcoming the challenge of how to write, as well as what to write, to maximise their chances of publishing in international scientific journals. The book uses analysis of the scientific article genre to provide clear processes for writing each section of a manuscript, starting with clear ‘story’ construction and packaging of results. Each learning step uses practical exercises to develop writing and data presentation skills based on reader analysis of well-written example papers. Strategies are presented for responding to referee comments, and for developing discipline-specific English language skills for manuscript writing and polishing. The book is designed for scientists who use English as a first or an additional language, and for individual scientists or mentors or a class setting. In response to reader requests, the new edition includes review articles and the full range of research article formats, as well as applying the book’s principles to writing funding applications. Web support for this book is available at www.writeresearch.com.au

The Mental Capacity Act (2005) governs decision-making processes on behalf of adults who are unable to give informed consent, whether they lose mental capacity at some point in their lives due to illness or injury or where the incapacitating condition has been present since birth. Legal Aspects of Mental Capacity will assist practitioners in understanding the basic provisions of the Act and how it applies to their professional responsibilities. It is also intended to be of assistance to the many carers who find themselves in the position of needing to make decisions on behalf of mentally incapacitated relatives and friends. Each chapter sets out the basis provisions, followed by a series of scenarios dealing with practical concerns which are discussed in the light of the new legislation. • A practical guide to the provisions of the Mental Capacity Act 2005 • Easily accessible for those with no legal background • Includes scenarios illustrating different legal points • Explores the background to the legislation, including determination of capacity and the definition of best interests Legal Aspects of Mental Capacity is an essential resource for all healthcare and social services professionals, patient services managers and carers working with those who lack the capacity to make their own decisions.

In keeping with the outstanding importance of lipophilicity in biosciences, this volume examines all its facets in more than twenty contributions from leading experts. It offers a thorough and highly topical survey of this rapidly developing field of research. Color plates demonstrating structural aspects, a vast number of references, and the straightforward presentation of the material make this volume a invaluable tool for all researchers involved in drug design or in the investigation of drug action.

Highly Commended in Health and social care in the 2017 BMA Medical Book Awards The Mental Capacity Act (2005) regulates decision making processes on behalf of adults who are unable to give informed consent, due to a loss in mental capacity (be that from birth, or due to an illness or injury at some point in their lives). Since the Act’s original conception the new Court of Protection is now firmly established, and there have been significant Supreme Court cases, as well as further guidance on the 2005 Act and major developments in the use and assessment for Deprivation of Liberty Safeguards. Thoroughly updated to take account of the many updates, developments and changes in legislation and guidance, the new edition of Dimond’s authoritative guide will be warmly welcome by practitioners and students who need to understand and work within the Mental Capacity Act, and how it applies to their professional responsibilities. A highly practical guide to the Mental Capacity Act and its provisions since its conception in 2005 Relevant for a wide range of practitioners and students within health and social care Highly readable and easily accessible, even for those with no legal background Includes a range of learning features, including scenarios, questions and answers, key summary points, and applications for practice. Legal Aspects of Mental Capacity is an essential resource for all healthcare and social services professionals, students patient services managers and carers working with those who lack the capacity to make their own decisions.

Margaret Cargill's background as a linguist and research communications educator and Patrick O'Connor's experience as both research scientist and educator synergize to improve both the science and art of scientific writing. If the authors' goal is to give scientists the tools to write and publish compelling, well documented, clear narratives that convey their work honestly and in proper context, they have succeeded admirably. Veterinary Pathology, July 2009 «[The book is] clearly written, has a logical step-by-step structure, is easy to read and contains a lot of sensible advice about how to get scientific work published in international journals. The book is a most useful addition to the literature covering scientific writing.» Aquaculture International, April 2009 Writing Scientific Research Articles: Strategy and Steps guides authors in how to write, as well as what to write, to improve their chances of having their articles accepted for publication in international, peer reviewed journals. The book is designed for scientists who use English as a first or an additional language; for research students and those who teach them paper writing skills; and for early-career researchers wanting to hone their skills as authors and mentors. It provides clear processes for selecting target journals and writing each section of a manuscript, starting with the results. The stepwise learning process uses practical exercises to develop writing and data presentation skills through analysis of well-written example papers. Strategies are presented for responding to referee comments, as well as ideas for developing discipline-specific English language skills for manuscript writing. The book is designed for use by individuals or in a class setting. Visit the companion site at www.writeresearch.com.au for more information.

This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.