Geostatistics. Modeling Spatial Uncertainty

A valuable guide to understanding the problem of quantifying uncertainty in dose response relations for toxic substances In today's scientific research, there exists the need to address the topic of uncertainty as it pertains to dose response modeling. Uncertainty Modeling in Dose Response is the first book of its kind to implement and compare different methods for quantifying the uncertainty in the probability of response, as a function of dose. This volume gathers leading researchers in the field to properly address the issue while communicating concepts from diverse viewpoints and incorporating valuable insights. The result is a collection that reveals the properties, strengths, and weaknesses that exist in the various approaches to bench test problems. This book works with four bench test problems that were taken from real bioassay data for hazardous substances currently under study by the United States Environmental Protection Agency (EPA). The use of actual data provides readers with information that is relevant and representative of the current work being done in the field. Leading contributors from the toxicology and risk assessment communities have applied their methods to quantify model uncertainty in dose response for each case by employing various approaches, including Benchmark Dose Software methods, probabilistic inversion with isotonic regression, nonparametric Bayesian modeling, and Bayesian model averaging. Each chapter is reviewed and critiqued from three professional points of view: risk analyst/regulator, statistician/mathematician, and toxicologist/epidemiologist. In addition, all methodologies are worked out in detail, allowing readers to replicate these analyses and gain a thorough understanding of the methods. Uncertainty Modeling in Dose Response is an excellent book for courses on risk analysis and biostatistics at the upper-undergraduate and graduate levels. It also serves as a valuable reference for risk assessment, toxicology, biostatistics, and environmental chemistry professionals who wish to expand their knowledge and expertise in statistical dose response modeling problems and approaches.

Modeling Uncertainty in the Earth Sciences highlights the various issues, techniques and practical modeling tools available for modeling the uncertainty of complex Earth systems and the impact that it has on practical situations. The aim of the book is to provide an introductory overview which covers a broad range of tried-and-tested tools. Descriptions of concepts, philosophies, challenges, methodologies and workflows give the reader an understanding of the best way to make decisions under uncertainty for Earth Science problems. The book covers key issues such as: Spatial and time aspect; large complexity and dimensionality; computation power; costs of 'engineering' the Earth; uncertainty in the modeling and decision process. Focusing on reliable and practical methods this book provides an invaluable primer for the complex area of decision making with uncertainty in the Earth Sciences.

Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysis Bridging the gap between agent-based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent-based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation-based, and geo-spatial domains in order to identify and analyze relationships between various transmission variables of the disease. Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location-specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigation Discussions on the best modeling practices in an effort to achieve improved efficacy, cost-effectiveness, ecological soundness, and sustainability of vector control for malaria An overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria study A companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and houses Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease-related projects. The book is also ideal for graduate-level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology.

Statistical Methods for Spatial and Spatio-Temporal Data Analysis provides a complete range of spatio-temporal covariance functions and discusses ways of constructing them. This book is a unified approach to modeling spatial and spatio-temporal data together with significant developments in statistical methodology with applications in R. This book includes: Methods for selecting valid covariance functions from the empirical counterparts that overcome the existing limitations of the traditional methods. The most innovative developments in the different steps of the kriging process. An up-to-date account of strategies for dealing with data evolving in space and time. An accompanying website featuring R code and examples

This book provides a comprehensive introduction to multiple-point geostatistics, where spatial continuity is described using training images. Multiple-point geostatistics aims at bridging the gap between physical modelling/realism and spatio-temporal stochastic modelling. The book provides an overview of this new field in three parts. Part I presents a conceptual comparison between traditional random function theory and stochastic modelling based on training images, where random function theory is not always used. Part II covers in detail various algorithms and methodologies starting from basic building blocks in statistical science and computer science. Concepts such as non-stationary and multi-variate modeling, consistency between data and model, the construction of training images and inverse modelling are treated. Part III covers three example application areas, namely, reservoir modelling, mineral resources modelling and climate model downscaling. This book will be an invaluable reference for students, researchers and practitioners of all areas of the Earth Sciences where forecasting based on spatio-temporal data is performed.

Geostatistics is essential for environmental scientists. Weather and climate vary from place to place, soil varies at every scale at which it is examined, and even man-made attributes – such as the distribution of pollution – vary. The techniques used in geostatistics are ideally suited to the needs of environmental scientists, who use them to make the best of sparse data for prediction, and top plan future surveys when resources are limited. Geostatistical technology has advanced much in the last few years and many of these developments are being incorporated into the practitioner’s repertoire. This second edition describes these techniques for environmental scientists. Topics such as stochastic simulation, sampling, data screening, spatial covariances, the variogram and its modeling, and spatial prediction by kriging are described in rich detail. At each stage the underlying theory is fully explained, and the rationale behind the choices given, allowing the reader to appreciate the assumptions and constraints involved.

Features modern research and methodology on the spread of infectious diseases and showcases a broad range of multi-disciplinary and state-of-the-art techniques on geo-simulation, geo-visualization, remote sensing, metapopulation modeling, cloud computing, and pattern analysis Given the ongoing risk of infectious diseases worldwide, it is crucial to develop appropriate analysis methods, models, and tools to assess and predict the spread of disease and evaluate the risk. Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features mathematical and spatial modeling approaches that integrate applications from various fields such as geo-computation and simulation, spatial analytics, mathematics, statistics, epidemiology, and health policy. In addition, the book captures the latest advances in the use of geographic information system (GIS), global positioning system (GPS), and other location-based technologies in the spatial and temporal study of infectious diseases. Highlighting the current practices and methodology via various infectious disease studies, Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features: Approaches to better use infectious disease data collected from various sources for analysis and modeling purposes Examples of disease spreading dynamics, including West Nile virus, bird flu, Lyme disease, pandemic influenza (H1N1), and schistosomiasis Modern techniques such as Smartphone use in spatio-temporal usage data, cloud computing-enabled cluster detection, and communicable disease geo-simulation based on human mobility An overview of different mathematical, statistical, spatial modeling, and geo-simulation techniques Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases is an excellent resource for researchers and scientists who use, manage, or analyze infectious disease data, need to learn various traditional and advanced analytical methods and modeling techniques, and become aware of different issues and challenges related to infectious disease modeling and simulation. The book is also a useful textbook and/or supplement for upper-undergraduate and graduate-level courses in bioinformatics, biostatistics, public health and policy, and epidemiology.

Praise for the First Edition «…a reference for everyone who is interested in knowing and handling uncertainty.» —Journal of Applied Statistics The critically acclaimed First Edition of Understanding Uncertainty provided a study of uncertainty addressed to scholars in all fields, showing that uncertainty could be measured by probability, and that probability obeyed three basic rules that enabled uncertainty to be handled sensibly in everyday life. These ideas were extended to embrace the scientific method and to show how decisions, containing an uncertain element, could be rationally made. Featuring new material, the Revised Edition remains the go-to guide for uncertainty and decision making, providing further applications at an accessible level including: A critical study of transitivity, a basic concept in probability A discussion of how the failure of the financial sector to use the proper approach to uncertainty may have contributed to the recent recession A consideration of betting, showing that a bookmaker's odds are not expressions of probability Applications of the book’s thesis to statistics A demonstration that some techniques currently popular in statistics, like significance tests, may be unsound, even seriously misleading, because they violate the rules of probability Understanding Uncertainty, Revised Edition is ideal for students studying probability or statistics and for anyone interested in one of the most fascinating and vibrant fields of study in contemporary science and mathematics.

Deal with information and uncertainty properly and efficiently using tools emerging from generalized information theory Uncertainty and Information: Foundations of Generalized Information Theory contains comprehensive and up-to-date coverage of results that have emerged from a research program begun by the author in the early 1990s under the name «generalized information theory» (GIT). This ongoing research program aims to develop a formal mathematical treatment of the interrelated concepts of uncertainty and information in all their varieties. In GIT, as in classical information theory, uncertainty (predictive, retrodictive, diagnostic, prescriptive, and the like) is viewed as a manifestation of information deficiency, while information is viewed as anything capable of reducing the uncertainty. A broad conceptual framework for GIT is obtained by expanding the formalized language of classical set theory to include more expressive formalized languages based on fuzzy sets of various types, and by expanding classical theory of additive measures to include more expressive non-additive measures of various types. This landmark book examines each of several theories for dealing with particular types of uncertainty at the following four levels: * Mathematical formalization of the conceived type of uncertainty * Calculus for manipulating this particular type of uncertainty * Justifiable ways of measuring the amount of uncertainty in any situation formalizable in the theory * Methodological aspects of the theory With extensive use of examples and illustrations to clarify complex material and demonstrate practical applications, generous historical and bibliographical notes, end-of-chapter exercises to test readers' newfound knowledge, glossaries, and an Instructor's Manual, this is an excellent graduate-level textbook, as well as an outstanding reference for researchers and practitioners who deal with the various problems involving uncertainty and information. An Instructor's Manual presenting detailed solutions to all the problems in the book is available from the Wiley editorial department.

SPATIAL ANALYSIS Explore the foundations and latest developments in spatial statistical analysis In Spatial Analysis, two distinguished authors deliver a practical and insightful exploration of the statistical investigation of the interdependence of random variables as a function of their spatial proximity. The book expertly blends theory and application, offering numerous worked examples and exercises at the end of each chapter. Increasingly relevant to fields as diverse as epidemiology, geography, geology, image analysis, and machine learning, spatial statistics is becoming more important to a wide range of specialists and professionals. The book includes: Thorough introduction to stationary random fields, intrinsic and generalized random fields, and stochastic models Comprehensive exploration of the estimation of spatial structure Practical discussion of kriging and the spatial linear model Spatial Analysis is an invaluable resource for advanced undergraduate and postgraduate students in statistics, data science, digital imaging, geostatistics, and agriculture. It’s also an accessible reference for professionals who are required to use spatial models in their work.