Immune Dysfunction and Immunotherapy in Heart Disease

There has been very little written on the interaction of the liver and kidney. This book addresses the increasing incidence and significance of diseases, such as ascites, renal dysfunction, cirrhosis and hypertension where both organs are involved. This textbook is essential, even for confirmed practitioners and contains current information regarding treatment and therapy for patients with cirrhosis and ascites, clearly and effectively presented by the top international experts within this field. The second edition is entirely revised and updated and places greater emphasis on therapy.

Echocardiography is essential in the practice of pediatric cardiology. A clinical pediatric cardiologist is expected to be adept at the non-invasive diagnosis of congenital heart disease and those who plan to specialize in echocardiography will need to have knowledge of advanced techniques. Echocardiography in Pediatric and Congenital Heart Disease addresses the needs of trainees and practitioners in this field, filling a void caused by the lack of material in this fast-growing area. This new title comprehensively covers the echocardiographic assessment of congenital heart disease, from the fetus to the adult, plus acquired heart disease in children. Topics covered include: ultrasound physics laboratory set-up a protocol for a standard pediatric echocardiogram quantitative methods of echocardiographic evaluation, including assessment of diastolic function in depth coverage of congenital cardiovascular malformations acquired pediatric heart disease topics of special interest, such as 3D echocardiography, transesophageal echocardiography, and fetal echocardiography The approach of this book is a major advancement for educational materials in the field of pediatric cardiology, and greatly enhances the experience for the reader. An accompanying DVD with moving images of the subjects covered in the textbook will further enhance the learning experience.

The new edition of this practical guide draws on the clinical skills of a wide range of international experts to help you recognize and manage heart disease in pregnancy. Designed for on-the-spot use, this convenient and concise text helps you identify a cardiac problem, understand its pathophysiology, and respond appropriately. Under the careful editorial direction of Drs. Oakley and Warnes, the Second Edition introduces new contributors from North America and Europe as well as new chapters on: pulmonary hypertension rheumatic heart disease artificial heart valves Marfan syndrome auto-immune diseases hypertrophic cardiomyopathy rhythm disorders hypertension cardiac intervention The entire book is scrupulously updated to reflect the most current standards of care. The contributors – all recognized leaders in their respective fields – outline the pathway to diagnosis and appropriate management by a multi-disciplinary team. Although heart disease is the leading medical cause of maternal death, clinical trials in this population are few and the evidence base is small. The expert recommendations in Heart Disease in Pregnancy, Second Edition, are a welcome source of information for cardiologists, obstetricians, general practitioners, and all members of the patient care team.

This comprehensive textbook on the echocardiographic assessment of pediatric and congenital heart disease has been updated for a second edition with an emphasis on new technologies. This highly-illustrated full-color reference contains over 1200 figures, and offers over 600 video clips on a companion website. Fully updated, with new chapters on the assessment of the post-Fontan procedure patient and on pregnancy and heart disease Each lesion chapter includes new section highlighting the key elements of the echocardiogram(s) Written by experts from the leading centers around the world, with numerous new authors Revision emphasizes new technologies and quality of images Comprehensive content contains overview of ultrasound physics, discussion of laboratory set-up, protocol for a standard pediatric echocardiogram and quantitative methods of echocardiographic evaluation, including assessment of diastolic function Also includes special techniques and topics including 3D echocardiography, intraoperative echocardiography, and fetal echocardiography

Biomarkers in Heart Disease is the first title in the AHA Clinical Series and is aimed at meeting the needs of clinicians, providing cardiologists, internists, emergency physicians, laboratorians, and other healthcare providers with a clear understanding of the role of biomarkers in contemporary cardiovascular medicine. The book covers both the strengths and pitfalls of currently available markers, and provides information on the most promising biomarkers that are likely to impact practice in the next few years. It is divided into four parts, organized around clinical scenarios rather than individual biomarkers. This book will help the practicing physician decide which biomarkers to measure, when to measure them, how to interpret the results and how to make decisions based on the test result.

With a growing population of young patients with congenital heart disease reaching adulthood, this unique new book offers an in-depth guide to managing the challenges and issues related to device therapy in this patient group. The only book resource dedicated to pacing, cardiac resynchronization therapy and ICD therapy for the pediatric and congenital heart disease patient Contains practical advice for pacemaker and ICD implantation, programming, trouble-shooting, managing complications and follow up Up-to-date with the latest in device technology Contains multiple graphics, device electrogram tracings, and radiographic images for clarity Includes video clips and over 150 multiple choice questions with extended answers on companion website, ideal for self test An invaluable resource for both the specialist pediatric cardiologist and the general cardiologist responsible for children with heart disease and pacing devices

The ECG is a fundamental diagnostic tool in cardiology, allowing accurate diagnosis and monitoring of acute and chronic ischemic heart disease. In this most comprehensive book of its kind, internationally renowned authors correlate electrocardiographic recordings with anatomical patterns of myocardial ischemia to improve the diagnosis and management of patients with ischemic heart disease. The book is structured in two sections. Part One covers electrocardiographic patterns of ischemia, injury and infarction. • Each chapter discusses a different ECG abnormality in turn, clearly explaining the ischemic insults and electrophysiological mechanisms underlying each pattern to promote rapid and accurate interpretation of the ECG in the clinical setting. • ECG abnormalities are correlated with myocardial anatomy and coronary angiography to produce a series of practical diagnostic algorithms that allow the clinician to identify not only the occluded artery but the precise location of the occlusion within the artery, facilitating appropriate therapeutic decisions. • The authors also propose a new classification of Q-wave myocardial infarctions based on imaging correlations with advanced techniques such as contrast-enhanced cardiac magnetic resonance. Part Two of the book covers the ECG in clinical practice. Each chapter focuses on a different clinical syndrome, describing the role of the ECG in a global approach to the diagnosis, prognosis and risk stratification of patients with acute and chronic ischemic heart disease and guiding clinical decision-making. Extensively referenced and illustrated throughout, this book is highly recommended for any clinician involved in the diagnosis and management of ischemic heart disease.

Infants, children and adolescents with congenital heart disease (CHD) are a challenge to manage and an ever-increasing number are reaching adulthood. CHD is one of the most important topics in cardiology today, yet this book is the only clinically-orientated monograph devoted exclusively to ventricular function and blood flow as it relates to CHD. Written by a distinguished panel of cardiologists, bioengineers, physiologists, and clinical investigators, Ventricular Function and Blood Flow in Congenital Heart Disease is an extensive and comprehensive presentation of the key aspects of this branch of CHD.

This comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system. Compiled by a team of world-renowned editors and contributors covering the fields of transplantation, nephrology, pharmacology, and immunology, the book covers all anti-rejection drugs according to a set template and includes the efficacy of each for specific diseases.