LTE and the Evolution to 4G Wireless. Design and Measurement Challenges

Clinical trials tasks and activities are widely diverse and require certain skill sets to both plan and execute. This book provides professionals in the field of clinical research with valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It discusses key obstacles such as challenges to patient recruitment, investigator and study site selection, and dealing with compliance issues. Through practical examples, professionals working with medical device clinical trials will discover the appropriate steps to take.

Natural ventilation is considered a prerequisite for sustainable buildings and is therefore in line with current trends in the construction industry. The design of naturally ventilated buildings is more difficult and carries greater risk than those that are mechanically ventilated. A successful result relies increasingly on a good understanding of the abilities and limitations of the theoretical and experimental procedures that are used for design. There are two ways to naturally ventilate a building: wind driven ventilation and stack ventilation. The majority of buildings employing natural ventilation rely primarily on wind driven ventilation, but the most efficient design should implement both types. Natural Ventilation of Buildings: Theory, Measurement and Design comprehensively explains the fundamentals of the theory and measurement of natural ventilation, as well as the current state of knowledge and how this can be applied to design. The book also describes the theoretical and experimental techniques to the practical problems faced by designers. Particular attention is given to the limitations of the various techniques and the associated uncertainties. Key features: Comprehensive coverage of the theory and measurement of natural ventilation Detailed coverage of the relevance and application of theoretical and experimental techniques to design Highlighting of the strengths and weaknesses of techniques and their errors and uncertainties Comprehensive coverage of mathematical models, including CFD Two chapters dedicated to design procedures and another devoted to the basic principles of fluid mechanics that are relevant to ventilation This comprehensive account of the fundamentals for natural ventilation design will be invaluable to undergraduates and postgraduates who wish to gain an understanding of the topic for the purpose of research or design. The book should also provide a useful source of reference for more experienced industry practitioners.

Natural ventilation is considered a prerequisite for sustainable buildings and is therefore in line with current trends in the construction industry. The design of naturally ventilated buildings is more difficult and carries greater risk than those that are mechanically ventilated. A successful result relies increasingly on a good understanding of the abilities and limitations of the theoretical and experimental procedures that are used for design. There are two ways to naturally ventilate a building: wind driven ventilation and stack ventilation. The majority of buildings employing natural ventilation rely primarily on wind driven ventilation, but the most efficient design should implement both types. Natural Ventilation of Buildings: Theory, Measurement and Design comprehensively explains the fundamentals of the theory and measurement of natural ventilation, as well as the current state of knowledge and how this can be applied to design. The book also describes the theoretical and experimental techniques to the practical problems faced by designers. Particular attention is given to the limitations of the various techniques and the associated uncertainties. Key features: Comprehensive coverage of the theory and measurement of natural ventilation Detailed coverage of the relevance and application of theoretical and experimental techniques to design Highlighting of the strengths and weaknesses of techniques and their errors and uncertainties Comprehensive coverage of mathematical models, including CFD Two chapters dedicated to design procedures and another devoted to the basic principles of fluid mechanics that are relevant to ventilation This comprehensive account of the fundamentals for natural ventilation design will be invaluable to undergraduates and postgraduates who wish to gain an understanding of the topic for the purpose of research or design. The book should also provide a useful source of reference for more experienced industry practitioners.

A comprehensive guide to the structure, synergy, and challenges in U.S. health care delivery Introduction to Health Care Services: Foundations and Challenges offers new insights into the most important sectors of the United States' health care industry and the many challenges the future holds. Designed to provide a comprehensive and up-to-date understanding of the system, this textbook covers the many facets of health care delivery and details the interaction of health, environments, organizations, populations, and the health professions. Written by authors with decades of experience teaching and working in health care administration and management, the book examines the current state and changing face of health care delivery in the United States. Each chapter includes learning objectives and discussion questions that help guide and engage deeper consideration of the issues at hand, providing a comprehensive approach for students. Cases studies demonstrating innovations in the delivery of health care services are also presented. Health care administration requires a thorough understanding of the multiple systems that define and shape the delivery of health care in the United States. At the same time, it is important for students to gain an appreciation of the dilemma confronting policy makers, providers, and patients in the struggle to balance cost, quality, and access. Introduction to Health Care Services: Foundations and Challenges is an in-depth examination of the major health care issues and policy changes that have had an impact on the U.S. health care delivery system. Includes information on U.S. health care delivery, from care to cost, and the forces of change Focuses on major industry players, including providers, insurers, and facilities Highlights challenges facing health care delivery in the future, including physician shortages, quality care, and the chronic disease epidemic The U.S. health care system is undergoing major reform, and the effects will ripple across every sector of the industry. Introduction to Health Care Services: Foundations and Challenges gives students a complete introduction to understanding the issues and ramifications.

Now in its fifth edition, the bestselling book on UMTS has been updated to cover 3GPP WCDMA and High Speed Packet Access (HSPA) from Release 99 to Release 9. Written by leading experts in the field, the book explains HSPA performance based on simulations and field experience, and illustrates the benefits of HSPA evolution (HSPA+) both from the operators and from the end user?s perspective. It continues to provide updated descriptions of the 3GPP standard including the physical layer, radio protocols on layers 1-3 and a system architecture description. The challenges and solutions regarding terminal RF design are also discussed, including the benefits of HSPA+ power saving features. There is also the addition of a new chapter on femto cells as part of the updates to this fifth edition. Key updates include: HSPA evolution (HSPA+); Multicarrier HSPA solutions; HSPA femto cells (home base stations); TD-SCDMA system description; Terminal power consumption optimization. Updated description of LTE

An effective, quantitative approach for estimating and managing software projects How many people do I need? When will the quality be good enough for commercial sale? Can this really be done in two weeks? Rather than relying on instinct, the authors of Software Measurement and Estimation offer a new, tested approach that includes the quantitative tools, data, and knowledge needed to make sound estimations. The text begins with the foundations of measurement, identifies the appropriate metrics, and then focuses on techniques and tools for estimating the effort needed to reach a given level of quality and performance for a software project. All the factors that impact estimations are thoroughly examined, giving you the tools needed to regularly adjust and improve your estimations to complete a project on time, within budget, and at an expected level of quality. This text includes several features that have proven to be successful in making the material accessible and easy to master: * Simple, straightforward style and logical presentation and organization enables you to build a solid foundation of theory and techniques to tackle complex estimations * Examples, provided throughout the text, illustrate how to use theory to solve real-world problems * Projects, included in each chapter, enable you to apply your newfound knowledge and skills * Techniques for effective communication of quantitative data help you convey your findings and recommendations to peers and management Software Measurement and Estimation: A Practical Approach allows practicing software engineers and managers to better estimate, manage, and effectively communicate the plans and progress of their software projects. With its classroom-tested features, this is an excellent textbook for advanced undergraduate-level and graduate students in computer science and software engineering. An Instructor Support FTP site is available from the Wiley editorial department.

LTE- A and Next Generation Wireless Networks: Channel Modeling and Performance describes recent advances in propagation and channel modeling necessary for simulating next generation wireless systems. Due to the radio spectrum scarcity, two fundamental changes are anticipated compared to the current status. Firstly, the strict reservation of a specific band for a unique standard could evolve toward a priority policy allowing the co-existence of secondary users in a band allocated to a primary system. Secondly, a huge increase of the number of cells is expected by combining outdoor base stations with smaller cells such as pico/femto cells and relays. This evolution is accompanied with the emergence of cognitive radio that becomes a reality in terminals together with the development of self-organization capabilities and distributed cooperative behaviors. The book is divided into three parts: Part I addresses the fundamentals (e.g. technologies, channel modeling principles etc.) Part II addresses propagation and modeling discussing topics such as indoor propagation, outdoor propagation, etc. Part III explores system performance and applications (e.g. MIMO Over-the-air testing, electromagnetic safety, etc).

A technological overview of LTE and WiMAX LTE, WiMAX and WLAN Network Design, Optimization and Performance Analysis provides a practical guide to LTE and WiMAX technologies introducing various tools and concepts used within. In addition, topics such as traffic modelling of IP-centric networks, RF propagation, fading, mobility, and indoor coverage are explored; new techniques which increase throughput such as MIMO and AAS technology are highlighted; and simulation, network design and performance analysis are also examined. Finally, in the latter part of the book Korowajczuk gives a step-by-step guide to network design, providing readers with the capability to build reliable and robust data networks. By focusing on LTE and WiMAX this book extends current network planning approaches to next generation wireless systems based on OFDMA, providing an essential resource for engineers and operators of fixed and wireless broadband data access networks. With information presented in a sequential format, LTE, WiMAX and WLAN Network Design, Optimization and Performance Analysis aids a progressive development of knowledge, complementing latter graduate and postgraduate courses while also providing a valuable resource to network designers, equipment vendors, reference material, operators, consultants, and regulators. Key Features: One of the first books to comprehensively explain and evaluate LTE Provides an unique explanation of the basic concepts involved in wireless broadband technologies and their applications in LTE, WiMAX, and WLAN before progressing to the network design Demonstrates the application of network planning for LTE and WiMAX with theoretical and practical approaches Includes all aspects of system design and optimization, such as dynamic traffic simulations, multi-layered traffic analysis, statistical interference analysis, and performance estimations

Facilitates both the understanding and adoption of 802.1aq as a networking solution 802.1aq Shortest Path Bridging (SPB) is a technology that greatly simplifies the creation and configuration of carrier, enterprise, and cloud computing networks—by using modern computing power to deprecate signaling, and to integrate multicast, multipath routing, and large-scale virtualization. It is arguably one of the most significant enhancements in Ethernet's history. 802.1aq Shortest Path Bridging Design and Evolution explains both the «what» and the «why» of the technology standard being set today. It covers which decisions were elective and which were dictated by the design goals by using a multipart approach that first explains what SPB is, before transitioning into narrative form to describe the design processes and decisions behind it. To make SPB accessible to the data networking professional from multiple perspectives, the book: Provides a «Reader's Companion» to the standard Dissects the different elements of SPB Offers applications and potential futures for the technology 802.1aq Shortest Path Bridging Design and Evolution will appeal to system implementers, system and network architects, academics, IT professionals, and general networking professionals.

RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects.