Microarray Quality Control

STATISTICAL QUALITY CONTROL Provides a basic understanding of statistical quality control (SQC) and demonstrates how to apply the techniques of SQC to improve the quality of products in various sectors This book introduces Statistical Quality Control and the elements of Six Sigma Methodology, illustrating the widespread applications that both have for a multitude of areas, including manufacturing, finance, transportation, and more. It places emphasis on both the theory and application of various SQC techniques and offers a large number of examples using data encountered in real life situations to support each theoretical concept. Statistical Quality Control: Using MINITAB, R, JMP and Python begins with a brief discussion of the different types of data encountered in various fields of statistical applications and introduces graphical and numerical tools needed to conduct preliminary analysis of the data. It then discusses the basic concept of statistical quality control (SQC) and Six Sigma Methodology and examines the different types of sampling methods encountered when sampling schemes are used to study certain populations. The book also covers Phase 1 Control Charts for variables and attributes; Phase II Control Charts to detect small shifts; the various types of Process Capability Indices (CPI); certain aspects of Measurement System Analysis (MSA); various aspects of PRE-control; and more. This helpful guide alsoFocuses on the learning and understanding of statistical quality control for second and third year undergraduates and practitioners in the fieldDiscusses aspects of Six Sigma MethodologyTeaches readers to use MINITAB, R, JMP and Python to create and analyze chartsRequires no previous knowledge of statistical theoryIs supplemented by an instructor-only book companion site featuring data sets and a solutions manual to all problems, as well as a student book companion site that includes data sets and a solutions manual to all odd-numbered problems Statistical Quality Control: Using MINITAB, R, JMP and Python is an excellent book for students studying engineering, statistics, management studies, and other related fields and who are interested in learning various techniques of statistical quality control. It also serves as a desk reference for practitioners who work to improve quality in various sectors, such as manufacturing, service, transportation, medical, oil, and financial institutions. It‘s also useful for those who use Six Sigma techniques to improve the quality of products in such areas.

This book is the first of its kind in the field of protein microarrays and addresses novel strategies for constructing highly functional and biocompatible microarrays for screening proteins. The list of authors consisting of world leading experts provide a roadmap for solving the complex challenges that are currently faced while monitoring protein-protein interactions over a wide range of microarray platforms. In doing so, they also offer a comprehensive overview of microarray surface chemistry, detection technologies, fabrication options for array development, and data analysis of numerous types of protein interactions. Topics covered include: -Types of biomolecular interactions -Surface chemistry -Detection technologies -Spotting technologies -Bioinformatics/data analysis. While primarily intended to serve as a reference for researchers and students embarking on the exciting fields of proteomics, drug discovery and clinical diagnostics, this technology is also expected to potentially impact the areas of food diagnostics, environmental monitoring and national security.

A statistical approach to the principles of quality control and management Incorporating modern ideas, methods, and philosophies of quality management, Fundamentals of Quality Control and Improvement, Fourth Edition presents a quantitative approach to management-oriented techniques and enforces the integration of statistical concepts into quality assurance methods. Utilizing a sound theoretical foundation and illustrating procedural techniques through real-world examples, the timely new edition bridges the gap between statistical quality control and quality management. Promoting a unique approach, the book focuses on the use of experimental design concepts as well as the Taguchi method for creating product/process designs that successfully incorporate customer needs, improve lead time, and reduce costs. The Fourth Edition of Fundamentals of Quality Control and Improvement also includes: New topical coverage on risk-adjustment, capability indices, model building using regression, and survival analysis Updated examples and exercises that enhance the readers’ understanding of the concepts Discussions on the integration of statistical concepts to decision making in the realm of quality assurance Additional concepts, tools, techniques, and issues in the field of health care and health care quality A unique display and analysis of customer satisfaction data through surveys with strategic implications on decision making, based on the degree of satisfaction and the degree of importance of survey items Fundamentals of Quality Control and Improvement, Fourth Edition is an ideal book for undergraduate and graduate-level courses in management, technology, and engineering. The book also serves as a valuable reference for practitioners and professionals interested in expanding their knowledge of statistical quality control, quality assurance, product/process design, total quality management, and/or Six Sigma training in quality improvement.

A multi-discipline, hands-on guide to microarray analysis of biological processes Analyzing Microarray Gene Expression Data provides a comprehensive review of available methodologies for the analysis of data derived from the latest DNA microarray technologies. Designed for biostatisticians entering the field of microarray analysis as well as biologists seeking to more effectively analyze their own experimental data, the text features a unique interdisciplinary approach and a combined academic and practical perspective that offers readers the most complete and applied coverage of the subject matter to date. Following a basic overview of the biological and technical principles behind microarray experimentation, the text provides a look at some of the most effective tools and procedures for achieving optimum reliability and reproducibility of research results, including: An in-depth account of the detection of genes that are differentially expressed across a number of classes of tissues Extensive coverage of both cluster analysis and discriminant analysis of microarray data and the growing applications of both methodologies A model-based approach to cluster analysis, with emphasis on the use of the EMMIX-GENE procedure for the clustering of tissue samples The latest data cleaning and normalization procedures The uses of microarray expression data for providing important prognostic information on the outcome of disease

Professor Woodall’s essay shows that this book represents a remarkable contribution, even by today’s standards, because of its contemporary thinking about the relationship between the specific topic of SQC and the broader company context of Quality Management. It also demonstrates the remarkable awareness of at least some young US engineers in the post-war period about the vital role of Statistical Quality Control in establishing and maintaining a competitive position. The book reveals that there was unsuspected knowledge extant immediately post-war, about the importance of Statistical Quality Control when appropriately applied in an industrial setting. It also helps to correct wide-spread historical misconceptions about who specifically was responsible for helping Japanese industry get back on its feet post-war, a task assigned to General Douglas Macarthur by President Truman and how Macarthur was indebted to Sarasohn.

This third book of a 3-volume set on Fracture Mechanics adds a pragmatic and supportive character to the previous volumes by focusing on case studies using corrected exercises that teachers, students or engineers will find extremely useful. Due to the wide themes approached in this series, it can also be used to organize work in this field in a new way, as well as in the maintenance of industrial plants. Several cases of sampling plans and their applications in industry are presented, as well as several solved case studies on the main indicators of capability according to ISO/TS 16949, ISO 8258 and FORD. This book distinguishes itself from other works in the field through its originality in presenting an educational approach which aims at helping practitioners both in academia and industry. It is intended for technicians, engineers, designers, students, and teachers working in the fields of engineering and vocational education. The main objective of the author is to provide an assessment of indicators of quality and reliability to aid in decision-making. To this end, an intuitive and practical approach, based on mathematical rigor, is recommended.

Relying on practical examples from the authors’ experience, this book provides a thorough and modern approach to controlling and monitoring microbial contaminations during the manufacturing of non-sterile pharmaceuticals. Offers a comprehensive guidance for non-sterile pharmaceuticals microbiological QA/QC Presents the latest developments in both regulatory expectations and technical advancements Provides guidance on statistical tools for risk assessment and trending of microbiological data Describes strategy and practical examples from the authors’ experience in globalized pharmaceutical companies and expert networks Offers a comprehensive guidance for non-sterile pharmaceuticals microbiological QA/QC Presents the latest developments in both regulatory expectations and technical advancements Provides guidance on statistical tools for risk assessment and trending of microbiological data Describes strategy and practical examples from the authors’ experience in globalized pharmaceutical companies and expert networks

Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on: * Image analysis * Experiment design * Automated analysis, integrated analysis, and systems biology * Interpretation of results Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.

Interface characterization and control are critical in the design and manufacture of high quality advanced materials, particularly, for nanomaterials. This proceedings features papers on interface science and technology that provide a unique and state-of-the art perspective on interface characterization and control. Articles from scientists and engineers from 11 different countries address interface control, high temperature interfaces, nanoparticle design, nanotechnology, suspension control, novel processing, particulate materials, microstructure, and hot gas cleaning. This unique volume will serve as a valuable reference for scientists and engineers interested in interfaces, particulate materials, and nanotechnology. Proceedings of the International Conference on ICCCI 2003, Kurashiki, Japan, 2003; Ceramic Transactions, Volume 146.