Neuroimaging in Addiction

DENTAL NEUROIMAGING Provides the latest neuroimaging-based evidence on the brain mechanisms of oral functions Dental Neuroimaging: The Role of the Brain in Oral Functions provides an up-to-date overview of neuroimaging research on the neural mechanisms underlying mastication, swallowing, sensory processing, and other oral topics. Divided into three parts, the book first introduces the theoretical framework of the brain-stomatognathic axis, clinical assessments for oral function, and neuroimaging methods. The second part presents recent neuroimaging findings of oral sensory and motor functions such as somatosensation, gustation, and orofacial pain and anxiety. The book concludes with a review of recent translational research and discussion of the application of neuroimaging in clinical management. Throughout the text, boxed sections highlight key information about cognitive neuroscience, imaging techniques, interpreting neuroimaging results, and relating research findings to clinical practice. Covers specific clinical applications of dental neuroimaging in geriatric dentistry and in brain plasticity and adaptation Summarizes classic research works in neuroscience and oral science Discusses potential clinical applications of neuroimaging in dental practice Features chapter summaries, further reading links, guided clinical scenarios, and numerous figures and tables Offering a systematic introduction to brain science and how it relates to dental medicine, Dental Neuroimaging: The Role of the Brain in Oral Functions is essential reading for students and researchers in disciplines such as neuroscience, neuroanatomy, oral physiology, dentistry and oral healthcare, speech therapy, and oral rehabilitation.

As neuroimaging becomes more widespread, it is increasingly being used in the courts, even though understanding and interpreting neuroimaging methods and results can be very challenging – even without attempting to evaluate their potential applications to forensic questions. The sheer volume of available information, research results, and opinions can seem intimidating to forensic practitioners and to mental health professionals in general. This will be the first book dedicated to this important topic. Designed as a reference for forensic psychiatrists, it starts with a brief overview of the psychiatric applications of the primary neuroimaging techniques currently in most widespread use, positron emission tomography (PET), single-photon emission computed tomography (SPECT), and magnetic resonance imaging (MRI). Subsequent chapters explore the current and potential uses of neuroimaging in civil and criminal forensic contexts. Diagnostic categories addressed include traumatic brain injury, dementia, psychopathy, paraphilias, psychoses and mood disorders. Legal concepts such as admissibility, relevance, and standards of proof are reviewed as they relate to the possible uses of neuroimaging findings in legal proceedings; prior precedents and court decisions are also reviewed. Novel potential applications of neuroimaging, including detection of deception and identification of memory or recognition, are addressed in dedicated chapters. There is a growing body of writing on the ethical implications of neuroimaging in the legal context, but this has largely been in bioethics journals that have limited readership among members of the mental health profession. Ethical questions generated by the rapidly evolving field of forensic neuroimaging are explored in detail in a dedicated chapter. This book will be of great use to practicing forensic psychiatrists, forensic psychologists and forensic neurologists as they are increasingly likely to find themselves being asked to give professional opinions regarding the impact of neuroimaging findings on medicolegal questions such as competence, criminal responsibility, personal injury and disability. The book will be an invaluable resource for forensic practitioners seeking to understand and navigate this new area.

Over recent years the study of addiction has moved from being a fragmented and under-developed area of science to become a forefront subject with its own identity. This book describes that fascinating process of evolution through a series of probing face-to-face interviews with the international scientists and other actors in the field who helped make the process happen. Unique in-depth interviews with 30 influential figures who have shaped modern addiction science. Ten commentaries from leading contemporary experts interpret this material by section. Recent history as base for future research planning and policy development

Свеча из чистейшего минерального воска, заключенная в позолоченный стакан, во время горения наполняет комнату густым древесно-ориентальным ароматом. Его пронизывают дымные бальзамные ноты ладана, припудренные ирисами и подчеркнутые пряными семенами моркови. В состав лимитированного новогоднего набора включили также фигурный фарфоровый клош авторства Маттео Чибика.

Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail to stop. The prevailing model for tobacco addiction is that nicotine from cigarettes rewards smoking and punishes abstinence, tapping into a motivational system of operant conditioning that requires no conscious awareness. However, there are also accounts which involve cognitive biases and the effect of nicotine on impulse control. The brain pathways involved have been studied extensively, but the role of different nicotine receptor subtypes and other neurotransmitter systems is still subject to debate. In western countries, cigarette smoking as an adult has a heritability of 30-50% and candidate genes have been identified that may contribute in part to addiction susceptibility. Many socio-cultural correlates of cigarette smoking have been established, but a comprehensive model that accounts for these and links them with the psychobiological aspects of nicotine addiction has not been forthcoming. Structured behavioural support programmes aid cessation attempts, as do a number of pharmacotherapies, most notably nicotine replacement treatments and bupropion, but the underlying mechanisms are unclear. This book deals with the problems involved in understanding and treating nicotine and tobacco addiction. Topics covered include the nature of the worldwide health problem posed by cigarette smoking, the psychodynamics of cigarette addiction, and the basic pharmacology and biochemistry of nicotine and its effect on the brain. Further chapters analyse the genetic basis of susceptibility to nicotine addiction. Finally, the contributors address approaches to therapy. A continuing theme in the discussions throughout the book is how best to treat nicotine addiction, given that many smokers would like to stop smoking but are unable to do so because of their addiction. This book will be of great value to all psychologists and psychiatrists working on addiction, specifically to nicotine but also to other compounds and behaviours. It will also be of interest to neuroscientists and pharmacologists working on nicotine receptors and the brain pathways involved in dependence, as well as to biochemists, molecular biologist and to public health officials.

Since 1960, the burden of adolescent illness has shifted from the traditional causes of disease to the more behavior-related problems, such as drinking, smoking and drug abuse (nearly half of American adolescents have used an illicit drug sometime during their life). Instilling in adolescents the knowledge, skills, and values that foster physical and mental health will require substantial changes in the way health professionals work and the way they connect with families, schools, and community organizations. At the same time, the major textbooks on addiction medicine and addiction psychiatry devote relatively little attention to the special problems of diagnosing and treating adolescent addicts. Similarly, the major textbooks on general and child and adolescent psychiatry direct relatively little attention to the issues surrounding adolescent addiction. The Clinical Handbook of Adolescent Addiction is one response to the challenge of meeting the mental health needs and behavior-related problems of addicted teenagers. The work has been edited as an independent project by members of the American Society for Adolescent Psychiatry, the oldest professional organization of psychiatrists devoted solely to the mental health care and treatment of teenagers in the USA. The forensic psychiatry perspective permeates the entire book. It will help to produce health providers with a deep and sensitive understanding of the developmental needs and behavior-related problems of adolescents. The Clinical Handbook of Adolescent Addiction is a practical tool for all those who help adolescents: practitioners of family medicine, general psychiatrists, child/adolescent psychiatrists, adolescent psychiatrists, addiction psychiatrists, non-psychiatric physicians specializing in addiction medicine, forensic psychiatrists, psychologists, clinical social workers, mental health administrators, Court/Probation/ Parole/Correctional health workers. The book is organized in a user-friendly format so that readers can easily locate the chapters that provide the information that is required. In some instances, topics of special importance deliberately have been addressed in more than one chapter, to illuminate the topics from a variety of vantage points. One aim of the editors is to move the topic from being a specialist area to a generalist one by providing tools for generalist to use.

Providing essential theoretical and practical guidelines for clinicians, educators, policymakers, and public health professionals, The Handbook of Addiction Treatment for Women is a comprehensive resource of the most current research and knowledge from recognized experts in the field of addiction and treatment. This much needed guide offers an historical context on the issue of women and addiction, examines the myriad challenges of the female addict, and includes recommendations for choosing a course of treatment that will meet the specific needs of an individual woman addict.

With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand complex neuroscience issues. The author illustrates medicinal chemistry's prominent role in treating addiction and covers specific drugs of abuse including narcotics, stimulants, depressants, nicotine, and marijuana. • Interprets complex neuro- biological and pharmacological information, like the drug-reward system, for medicinal chemists • Emphasizes neurotransmitters and neurochemical mechanisms of addictive drugs • Pulls together information on the many potential drug targets for treating addiction • Stresses unique medicinal chemistry problems when describing pharmacology testing methods and drug development

This volume provides a thorough and up-to-date synthesis of the expansive and highly influential literature from the last 30 years by bringing together contributions from leading authorities in the field, with emphasis placed on the most commonly investigated drugs of abuse. Emphasises the most commonly investigated drugs of abuse, including alcohol, cocaine, nicotine, and opiates Brings together the work of the leading authorities in all major areas of the field Provides novel coverage of cutting-edge methods for using cognitive neuroscience to advance the treatment of addiction, including real-time neurofeedback and brain stimulation methods Includes new material on emerging themes and future directions in the use of cognitive neuroscience to advance addiction science