New Mechanisms in Glucose Control

The book explores both the clinical presentation of serious diabetic emergencies (like ketoacidosis, hyperosmolar coma, and severe hyper and hypoglycemia) that consultants and hospital staff encounter in practice and the best methods of both managing the emergencies and also administering follow-up guidance/care. All chapters are clearly structured to highlight: definition of emergency; epidemiology; potential causes, diagnosis, clinical management (including problem areas), follow-up management/care; and patient advice. There are case studies to aid clinical understanding, as well as 5-7 multiple choice questions and several key points/take-home message boxes in every chapter.

Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.

How the Endocrine System Works is not another standard introduction to endocrinology, but an innovative and fun way to learn about the importance of the key glands in the human body and the hormones they control. It is explained in 9 easy-to-understand lectures, with additional material on the treatment and management of endocrine disorders. How the Endocrine System Works: • Is designed for those in need of a concise introduction to this fascinating area of medicine • Has been rigorously updated to reflect today’s endocrinology teaching • Includes more focus on the treatment and management of endocrine disorders • Features more on evidence-based medicine, obesity, epidemiology, and biostatistics • Includes summaries of key research which affects diagnostic criteria • Includes brand new case-based review questions at the end of each chapter • Features full-color diagrams throughout How the Endocrine System Works is the perfect introduction for all medical students, as well as for students of bioscience, and other healthcare disciplines.

Imaging in Endocrinology will provide endocrinologists and radiologists of all levels with an outstanding diagnostic imaging atlas to aid them in the diagnosis and management of all the major endocrine diseases they are likely to encounter. In full colour throughout, the 300 high-quality images consist of CT scans, MRI, NMR and histopathology slides, and are arranged by each specific endocrine condition, resulting in a visually outstanding and easily accessible tool that guides the user through exactly what to look out for and provides a practical and extremely useful aid in helping them formulate a diagnosis. Every major endocrine condition is covered in a specific section, including diseases of the thyroid, pituitary, reproductive and adrenal glands, the pancreas, bone metabolism problems, and the various forms of endocrine cancers. Each disease covered will offer a comparison of the normal findings so as to further assist in diagnosis. An accompanying website contains an online slide-atlas of all the figures in the book, to allow users to download all figures for use in presentations. Led by Paolo Pozzilli, an internationally-recognised expert in this field, the authors have assembled a wonderful collection of images that will be greatly valued by endocrinologists and radiologists alike, ensuring this is the perfect tool to consult when assessing patients with endocrine disease.

This new edition of the successful Staged Diabetes Management will again address the prominent issues of primary care diabetes management based on the International Diabetes Center’s “Staged Diabetes Management” program, which it advocates as part of its mission statement. This systematic treatment program consists of practical solutions to the detection and treatment of diabetes, its complications, and such areas as metabolic syndrome, pre-diabete,s and diabetes in children using evidence-based medicine. The text reviews the fundamental basis of diabetes management and then addresses treatment of each type of diabetes and the major micro- and macrovascular complications.