Primary and Stem Cells. Gene Transfer Technologies and Applications

Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology – two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.

A cutting-edge look at the application of micro and nanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stem cells/tissue engineering has seen an explosion of activity in recent years. This book provides a much-needed overview of these exciting developments, covering all aspects of micro and nanotechnologies, from the fundamental principles to the latest research to applications in regenerative medicine. Written and edited by the top researchers in the field, Micro and Nanotechnologies in Engineering Stem Cells and Tissues describes advances in material systems along with current techniques available for cell, tissue, and organ studies. Readers will gain tremendous insight into the state of the art of stem cells and tissue engineering, and learn how to use the technology in their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissue growth Various engineering approaches for stem cell, vascular tissue, and bone regeneration The design and processing of biocompatible polymers and other biomaterials Characterization of the interactions between cells and biomaterials Unrivaled among books of this kind, Micro and Nanotechnologies in Engineering Stem Cells and Tissues is the ultimate forward-looking reference for researchers in numerous disciplines, from engineering and materials science to biomedicine, and for anyone wishing to understand the trends in this transformative field.

Cell and Molecular Biology and Imaging of Stem Cells features original and review articles written by experts who have made significant contributions to stem cell biology and imaging. Chapters cover a broad spectrum of aspects of the field, including Stem cells from the Amniotic Fluid and Placenta, Biomaterials as Artificial Niches for Pluripotent Stem Cell Engineering, Low-Intensity Ultrasound in Stem Cells and Tissue Engineering, Mammalian Neo-Oogenesis from Ovarian Stem Cells, Oct4-EGFP Transgenic Pigs as a New Tool for Visualization of Pluripotent and Reprogrammed Cells, Regulation of Adult Intestinal Stem Cells, Stem Cell Therapy for Veterinary Orthopedic Lesions, Sex Steroid Combinations in Regenerative Medicine for Brain and Heart Diseases, Hair Follicle Stem Cells, The Potential of Using Induced Pluripotent Stem Cells in Skin Diseases, Mitochondrial Differentiation in Early Embryo Cells and Pluripotent Stem Cells, and The Role of Centrosomes in Cancer Stem Cell Functions. Cell and Molecular Biology and Imaging of Stem Cells addresses a wide variety of cell and molecular topics in unprecedented detail, and is a must-read for graduate students and academic and industry professionals in the expanding field of stem cell biology. Reviews new imaging tools and markers for cell and molecular imaging in stem cell biology. Covers novel aspects of stem cell imaging in reproductive biology and stem cell niches Includes chapters on the developing area of centrosome biology as it applies to embryonic and adult stem differentiation

Stem Cells, Craniofacial Development and Regeneration is an introduction to stem cells with an emphasis on their role in craniofacial development. Divided into five sections, chapters build from basic introductory information on the definition and characteristics of stem cells to more indepth explorations of their role in craniofacial development. Section I covers embryonic and adult stem cells with a focus on the craniofacial region, while sections II-IV cover the development and regeneration of craniofacial bone, tooth, temporomandibular joint, salivary glands and muscle. Concluding chapters describe the current, cutting-edge research utilizing stem cells for craniofacial tissue bioengineering to treat lost or damaged tissue. The authoritative resource for dentistry students as well as craniofacial researchers at the graduate and post-graduate level, Stem Cells, Craniofacial Development and Regeneration explores the rapidly expanding field of stem cells and regeneration from the perspective of the dentistry and craniofacial community, and points the way forward in areas of tissue bioengineering and craniofacial stem cell therapies.

A comprehensive and authoritative compilation of up-to-date developments in stem cell research and its use in toxicology and medicine Presented by internationally recognized investigators in this exciting field of scientific research Provides an insight into the current trends and future directions of research in this rapidly developing new field A valuable and excellent source of authoritative and up-to-date information for researchers, toxicologists, drug industry, risk assessors and regulators in academia, industry and government

The improvement of electrical energy efficiency is fast becoming one of the most essential areas of sustainability development, backed by political initiatives to control and reduce energy demand. Now a major topic in industry and the electrical engineering research community, engineers have started to focus on analysis, diagnosis and possible solutions. Owing to the complexity and cross-disciplinary nature of electrical energy efficiency issues, the optimal solution is often multi-faceted with a critical solutions evaluation component to ensure cost effectiveness. This single-source reference brings a practical focus to the subject of electrical energy efficiency, providing detailed theory and practical applications to enable engineers to find solutions for electroefficiency problems. It presents power supplier as well as electricity user perspectives and promotes routine implementation of good engineering practice. Key features include: a comprehensive overview of the different technologies involved in electroefficiency, outlining monitoring and control concepts and practical design techniques used in industrial applications; description of the current standards of electrical motors, with illustrative case studies showing how to achieve better design; up-to-date information on standarization, technologies, economic realities and energy efficiency indicators (the main types and international results); coverage on the quality and efficiency of distribution systems (the impact on distribution systems and loads, and the calculation of power losses in distribution lines and in power transformers). With invaluable practical advice, this book is suited to practicing electrical engineers, design engineers, installation designers, M&E designers, and economic engineers. It equips maintenance and energy managers, planners, and infrastructure managers with the necessary knowledge to properly evaluate the wealth of electrical energy efficiency solutions for large investments. This reference also provides interesting reading material for energy researchers, policy makers, consultants, postgraduate engineering students and final year undergraduate engineering students.

This book provides an invaluable introduction to inter-vehicular communications, demonstrating the networking and communication technologies for reducing fatalities, improving transportation efficiency, and minimising environmental impact. This book addresses the applications and technical aspects of radio-based vehicle-to-vehicle and vehicle-to-infrastructure communication that can be established by short- and medium range communication based on wireless local area network technology (primarily IEEE 802.11). It contains a coherent treatment of the important topics and technologies contributed by leading experts in the field, covering the potential applications for and their requirements on the communications system. The authors cover physical and medium access control layer issues with focus on IEEE 802.11-based systems, and show how many of the applications benefit when information is efficiently disseminated, and the techniques that provide attractive data aggregation (also includes design of the corresponding middleware). The book also considers issues such as IT-security (means and fundamental trade-off between security and privacy), current standardization activities such as IEEE 802.11p, and the IEEE 1609 standard series. Key Features: Covers the state-of-the-art in the field of vehicular inter-networks such as safety and efficiency applications, physical and medium access control layer issues, middleware, and security Shows how vehicular networks differ from other mobile networks and illustrates the idea of vehicle-to-vehicle communications with application scenarios and with current proofs of concept worldwide Addresses current standardization activities such as IEEE 802.11p and the IEEE 1609 standard series Offers a chapter on mobility models and their use for simulation of vehicular inter-networks Provides a coherent treatment of the important topics and technologies contributed by leading academic and industry experts in the field This book provides a reference for professional automotive technologists (OEMS and suppliers), professionals in the area of Intelligent Transportation Systems, and researchers attracted to the field of wireless vehicular communications. Third and fourth year undergraduate and graduate students will also find this book of interest. For additional information please visit http://www.vanetbook.com

Stem Cells: A Short Course is a comprehensive text for students delving into the rapidly evolving discipline of stem cell research. Comprised of eight chapters, the text addresses all of the major facets and disciplines related to stem cell biology and research. A brief history of stem cell research serves as an introduction, followed by coverage of stem cell fundamentals; chapters then explore embryonic and fetal amniotic stem cells, adult stem cells, nuclear reprogramming, and cancer stem cells. The book concludes with chapters on stem cell applications, including the role of stem cells in drug discovery and therapeutic applications in spinal cord injury, brain damage, neurological and autoimmune disorders, among others. Written by a leader in the field, Stem Cells: A Short Course appeals to both students and instructors alike, appealing to academic enthusiasm for stem cell research and applications.

This book contains material contributed by forward-looking scientists who work at the interface of stem cell research and applied science with the aim to improve human fetal safety and the understanding of human developmental and degenerative disorders. Provides important platforms and contemporary accounts of the state of stem cell research in the fields of toxicology and teratology Considers both in vitro uses of stem cells as platforms for teratology and also stem cellopathies, which are in vivo developmental and degenerative disorders Helps the pharmaceutical industry and safety and environmental authorities validate the status quo of in vitro toxicity test systems based on human pluripotent stem cells and their derivatives

A staple in any chemical engineering curriculum New edition has a stronger emphasis on membrane separations, chromatography and other adsorptive processes, ion exchange Discusses many developing topics in more depth in mass transfer operations, especially in the biological engineering area Covers in more detail phase equilibrium since distillation calculations are completely dependent on this principle Integrates computational software and problems using Mathcad Features 25-30 problems per chapter