Principles and Practice of Mixtures Toxicology

Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.

A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms

The renowned Principles and Practice of Geriatric Psychiatry, now in its third edition, addresses the social and biological concepts of geriatric mental health from an international perspective. Featuring contributions by distinguished authors from around the world, the book offers a distinctive angle on issues in this continually developing discipline. Principles and Practice of Geriatric Psychiatry provides a comprehensive review of: geriatric psychiatry spanning both psychiatric and non-psychiatric disorders scientific advances in service development specific clinical dilemmas New chapters on: genetics of aging somatoform disorders epidemiology of substance abuse somatoform disorders care of the dying patient Continuing the practice of earlier editions, the major sections of the book address aging, diagnosis and assessment and clinical conditions, incorporating an engaging discussion on substance abuse and schizophrenic disorders. Shorter sections include the presentation of mental illness in elderly people from different cultures—one of the most popular sections in previous editions. Learning and behavioural studies, as well as models of geriatric psychiatry practice, are covered extensively. This book provides a detailed overview of the entire range of mental illness in old age, presented within an accessible format. Principles and Practice of Geriatric Psychiatry is an essential read for psychiatrists, geriatricians, neurologists and psychologists. It is of particular use for instructors of general psychiatry programs and their residents.

This second edition of Principles and Practice of Travel Medicine has been extensively updated to provide a comprehensive description of travel medicine and is an invaluable reference resource to support the clinical practice of travel medicine. This new edition covers the many recent advances in the field, including the development of new and combined vaccines; malaria prophylaxis; emerging new infections; new hazards resulting from travel to long haul destinations; health tourism; and population movements. The chapter on vaccine-preventable diseases includes new developments in licensed vaccines, as well as continent-based recommendations for their administration. There are chapters on the travel health management of high risk travellers, including the diabetic traveller, the immuno-compromised, those with cardiovascular, renal, neurological, gastrointestinal, malignant and other disorders, psychological and psychiatric illnesses, pregnant women, children and the elderly. With increasing numbers of ever more adventurous travellers, there is discussion of travel medicine within extreme environments, whilst the chapter on space tourism may well be considered the future in travel medicine. Principles and Practice of Travel Medicine is an invaluable resource for health care professionals providing advice and clinical care to the traveller.

Gain a stronger foundation with optimal ground improvement Before you break ground on a new structure, you need to analyze the structure of the ground. Expert analysis and optimization of the geo-materials on your site can mean the difference between a lasting structure and a school in a sinkhole. Sometimes problematic geology is expected because of the location, but other times it's only unearthed once construction has begun. You need to be able to quickly adapt your project plan to include an improvement to unfavorable ground before the project can safely continue. Principles and Practice of Ground Improvement is the only comprehensive, up-to-date compendium of solutions to this critical aspect of civil engineering. Dr. Jie Han, registered Professional Engineer and preeminent voice in geotechnical engineering, is the ultimate guide to the methods and best practices of ground improvement. Han walks you through various ground improvement solutions and provides theoretical and practical advice for determining which technique fits each situation. Follow examples to find solutions to complex problems Complete homework problems to tackle issues that present themselves in the field Study design procedures for each technique to simplify field implementation Brush up on modern ground improvement technologies to keep abreast of all available options Principles and Practice of Ground Improvement can be used as a textbook, and includes Powerpoint slides for instructors. It's also a handy field reference for contractors and installers who actually implement plans. There are many ground improvement solutions out there, but there is no single right answer to every situation. Principles and Practice of Ground Improvement will give you the information you need to analyze the problem, then design and implement the best possible solution.

The long awaited second edition of Principles and Practice of Pharmaceutical Medicine provides an invaluable guide to all areas of drug development and medical aspects of marketing. The title has been extensively revised and expanded to include the latest regulatory and scientific developments. New chapters include: European Regulations Ethics of Pharmaceutical Medicine Licensing and Due Diligence Pharmacogenomics Encompassing the entire spectrum of pharmaceutical medicine, it is the most up-to-date international guide currently available. Review of the first edition: “This book was a joy to read and a joy to review. All pharmaceutical physicians should have a copy on their bookshelves, all pharmaceutical companies should have copies in their libraries.” —BRITISH ASSOCIATION OF PHARMACEUTICAL PHYSICIANS

This long-awaited second edition of the successful introduction to the fundamentals of heterogeneous catalysis is now completely revised and updated. Written by internationally acclaimed experts, this textbook includes fundamentals of adsorption, characterizing catalysts and their surfaces, the significance of pore structure and surface area, solid-state and surface chemistry, poisoning, promotion, deactivation and selectivity of catalysts, as well as catalytic process engineering. A final section provides a number of examples and case histories. With its color and numerous graphics plus references to help readers to easily find further reading, this is a pivotal work for an understanding of the principles involved.

This fifth edition of Principles and Practice of Pharmacology for Anaesthetists continues to provide a comprehensive scientific basis and a readable account of the principles of pharmacology, as well as practical guidance in the use of drugs that is relevant to clinical anaesthesia. With these concepts in mind: Every chapter in this new edition has been thoroughly revised and updated An additional chapter on Adverse Drug Reactions is included For ease of reference, the structures of many commonly used agents are featured, with their sites of isomerism, when appropriate Recommended International Non-proprietary Names (rINNs) are generally used for generic agents, although preference has been given to the current nomenclature for adrenaline and noradrenaline As in previous editions, a comprehensive glossary covering abbreviations and acronyms is included to aid the reader. Principles and Practice of Pharmacology for Anaesthetists is an invaluable resource, both for candidates of professional examinations in anaesthesia and the practising anaesthetist wishing to refresh their pharmacological knowledge.

Hydrogeology: Principles and Practice provides a comprehensive introduction to the study of hydrogeology to enable the reader to appreciate the significance of groundwater in meeting current and future water resource challenges. This new edition has been thoroughly updated to reflect advances in the field since 2004. The book presents a systematic approach to understanding groundwater. Earlier chapters explain the fundamental physical and chemical principles of hydrogeology, and later chapters feature groundwater investigation techniques in the context of catchment processes, as well as chapters on groundwater quality and contaminant hydrogeology. Unique features of the book are chapters on the applications of environmental isotopes and noble gases in the interpretation of aquifer evolution, and on regional characteristics such as topography, compaction and variable fluid density in the explanation of geological processes affecting past, present and future groundwater flow regimes. The last chapter discusses groundwater resources and environmental management, and examines the role of groundwater in integrated river basin management, including an assessment of possible adaptation responses to the impacts of climate change. Throughout the text, boxes and a set of colour plates drawn from the authors’ teaching and research experience are used to explain special topics and to illustrate international case studies ranging from transboundary aquifers and submarine groundwater discharge to the over-pressuring of groundwater in sedimentary basins. The appendices provide conversion tables and useful reference material, and include review questions and exercises, with answers, to help develop the reader’s knowledge and problem-solving skills in hydrogeology. This accessible textbook is essential reading for undergraduate and graduate students primarily in earth sciences, environmental sciences and physical geography with an interest in hydrogeology or groundwater science. The book will also find use among practitioners in hydrogeology, soil science, civil engineering and planning who are involved in environmental and resource protection issues requiring an understanding of groundwater. Additional resources can be found at: www.wiley.com/go/hiscock/hydrogeology