Quantitative MRI of the Brain

The progress of magnetic resonance imaging (MRI) as a clinical tool has been extraordinary, out-stripping the rate of development of any other imaging technique. There has been a huge increase in the practical applications of MRI techniques and its uses look likely to extend even further with the development of high speed gradients and pulse sequences. The Handbook of MRI Technique has proved highly successful in guiding the uninitiated through scanning techniques and helping more experienced technologists to improve image quality. The third edition of this highly successful book has been fully revised and updated to consider new technologies and developments essential to good practice. The book is split into two parts. Part 1 considers the main aspects of theory that relate to scanning and also includes practical tips on gating, equipment use, patient care and safety, and information on contrast media. Part 2 provides step by step instruction for examining each anatomical area, beginning with a basic anatomy section, followed by sections on indications, patient positioning, equipment, artefacts and tips on optimizing image quality. A section of problem-solving exercises completes the book. Now in full color throughout with over 200 illustrations this book will continue to appeal to radiographers new to MRI and regular users who are looking for information on alternative techniques and suggestions on protocol modifications. Completely revised and updated Over 100 brand new photographs and line drawings Written by technologists for technologists With contributions from MRI technologists in the USA and Australia Suitable for users of all types of MRI systems

Principles of Quantitative Development is a practical guide to designing, building and deploying a trading platform. It is also a lucid and succinct expos? on the trade life cycle and the business groups involved in managing it, bringing together the big picture of how a trade flows through the systems, and the role of a quantitative professional in the organization. The book begins by looking at the need and demand for in-house trading platforms, addressing the current trends in the industry. It then looks at the trade life cycle and its participants, from beginning to end, and then the functions within the front, middle and back office, giving the reader a full understanding and appreciation of the perspectives and needs of each function. The book then moves on to platform design, addressing all the fundamentals of platform design, system architecture, programming languages and choices. Finally, the book focuses on some of the more technical aspects of platform design and looks at traditional and new languages and approaches used in modern quantitative development. The book is accompanied by a CD-ROM, featuring a fully working option pricing tool with source code and project building instructions, illustrating the design principles discussed, and enabling the reader to develop a mini-trading platform. The book is also accompanied by a website http://pqd.thulasidas.com that contains updates and companion materials.

Principles of Quantitative Development is a practical guide to designing, building and deploying a trading platform. It is also a lucid and succinct expos? on the trade life cycle and the business groups involved in managing it, bringing together the big picture of how a trade flows through the systems, and the role of a quantitative professional in the organization. The book begins by looking at the need and demand for in-house trading platforms, addressing the current trends in the industry. It then looks at the trade life cycle and its participants, from beginning to end, and then the functions within the front, middle and back office, giving the reader a full understanding and appreciation of the perspectives and needs of each function. The book then moves on to platform design, addressing all the fundamentals of platform design, system architecture, programming languages and choices. Finally, the book focuses on some of the more technical aspects of platform design and looks at traditional and new languages and approaches used in modern quantitative development. The book is accompanied by a CD-ROM, featuring a fully working option pricing tool with source code and project building instructions, illustrating the design principles discussed, and enabling the reader to develop a mini-trading platform. The book is also accompanied by a website http://pqd.thulasidas.com that contains updates and companion materials.

This book provides a hands-on introduction to the construction and application of models to studies of vertebrate distribution, abundance, and habitat. The book is aimed at field biologists, conservation planners, and advanced undergraduate and postgraduate students who are involved with planning and analyzing conservation studies, and applying the results to conservation decisions. The book also acts as a bridge to more advanced and mathematically challenging coverage in the wider literature. Part I provides a basic background in population and community modeling. It introduces statistical models, and familiarizes the reader with important concepts in the design of monitoring and research programs. These programs provide the essential data that guide conservation decision making. Part II covers the principal methods used to estimate abundance, occupancy, demographic parameters, and community parameters, including occupancy sampling, sample counts, distance sampling, and capture-mark-recapture (for both closed and open populations). Emphasis is placed on practical aspects of designing and implementing field studies, and the proper analysis of data. Part III introduces structured decision making and adaptive management, in which predictive models are used to inform conservation decision makers on appropriate decisions in the face of uncertainty—with the goal of reducing uncertainty through monitoring and research. A detailed case study is used to illustrate each of these themes. Numerous worked examples and accompanying electronic material (on a website – http://www.blackwellpublishing.com/conroy – and accompanying CD) provide the details of model construction and application, and data analysis.

The rapid developments in magnetic resonance imaging (MRI) over the past 20 years have affirmed its supremacy over most other means of non-invasive exploration of the human body. This progress has had other consequences for imaging physicists: having knowledge about only one of the sides of MRI is nowadays no longer enough to develop new sequences or even to learn more about those that already exist. It is necessary to have a clear and precise view of all the fields explored today by this imaging technique, such as rapid imaging, flows, diffusion, perfusion or even functional MRI. This book aims to allow readers with the basics of physics and mathematics within the field MRI to easily immerse themselves in techniques that are not familiar to them. Pragmatic in approach, moving between the physics underlying the techniques being studied and the clinical examination of images, it will also be of interest to radiologists looking to define protocols or make better use of the images obtained. Contents 1. Flow. 2. Diffusion. 3. Perfusion. 4. Functional MRI. About the Authors Vincent Perrin is a specialist teacher in the fields of physics and chemistry.

Distributed systems employed in critical infrastructures must fulfill dependability, timeliness, and performance specifications. Since these systems most often operate in an unpredictable environment, their design and maintenance require quantitative evaluation of deterministic and probabilistic timed models. This need gave birth to an abundant literature devoted to formal modeling languages combined with analytical and simulative solution techniques The aim of the book is to provide an overview of techniques and methodologies dealing with such specific issues in the context of distributed systems and covering aspects such as performance evaluation, reliability/availability, energy efficiency, scalability, and sustainability. Specifically, techniques for checking and verifying if and how a distributed system satisfies the requirements, as well as how to properly evaluate non-functional aspects, or how to optimize the overall behavior of the system, are all discussed in the book. The scope has been selected to provide a thorough coverage on issues, models. and techniques relating to validation, evaluation and optimization of distributed systems. The key objective of this book is to help to bridge the gaps between modeling theory and the practice in distributed systems through specific examples.

Atlas of Small Animal CT & MRI is a highly illustrated diagnostic imaging guide to common clinical disorders of dogs and cats. Contains over 3,000 high quality CT, MRI and related diagnostic images Offers a unique approach emphasizing comparative imaging and pathologic correlation Focuses on important imaging features relevant to imaging diagnosis of disease in dogs and cats Written by internationally renowned experts in the field

Quantitative methods specifically tailored for the marine biologist While there are countless texts published on quantitative methods and many texts that cover quantitative terrestrial ecology, this text fills the need for the special quantitative problems confronting marine biologists and biological oceanographers. The author combines common quantitative techniques with recent advances in quantitative methodology and then demonstrates how these techniques can be used to study marine organisms, their behaviors, and their interactions with the environment. Readers learn how to better design experiments and sampling, employ sophisticated mathematical techniques, and accurately interpret and communicate the results. Most of this text is written at an introductory level, with a few topics that advance to more complex themes. Among the topics covered are plot/plotless sampling, biometrics, experimental design, game theory, optimization, time trends, modeling, and environmental impact assessments. Even readers new to quantitative methods will find the material accessible, with plenty of features to engage their interest, promote learning, and put their knowledge into practice: * One or more examples are provided to illustrate each individual quantitative technique presented in the text * The accompanying CD-ROM features two multimedia programs, several statistical programs, help to run complex statistical programs, and additional information amplifying topics covered in the text * References lead readers to additional information to pursue individual topics in greater depth Quantitative Analysis of Marine Biological Communities, with its extensive use of examples, is ideal for undergraduate and graduate students in marine biology. Marine biologists, regardless of their level of experience, will also discover new approaches to quantitative analysis tailored to the particular needs of their field.

Environmental Experience and Plasticity of the Developing Brain goes beyond the genetic basis of neurodevelopment. Chapters illuminate the external factors that can dramatically impact the brain early in life and, consequently, the eventual accomplishment of developmental milestones and the construction of adult behavior and personality. Authored and edited by leaders in this rapidly growing field, Environmental Experience and Plasticity of the Developing Brain not only surveys preexisting literature on the effects of environment versus genetics, but also discusses more recent studies on the impacts of neurodevelopment in terms of maternal stimulation, environmental enrichment and sensory deprivation. The book also includes key examples of environmental impacts on preexisting genetic syndromes leading to developmental disabilities. Focus is also given to the consequences of early adverse experience in primates, as well as neurobiological and behavioral consequences in institutionalized human children and the reversibility of such consequences. Environmental Experience and Plasticity of the Developing Brain encompasses a broad area of research in the field of developmental neurobiology and offers a unique combination of different examples of environmental factors affecting brain development and behavior.

Practical Small Animal MRI is the seminal reference for clinicians using Magnetic Resonance Imaging in the diagnosis and treatment of veterinary patients. Although MRI is used most frequently in the diagnosis of neurologic disorders, it also has significant application to other body systems. This book covers normal anatomy and specific clinical conditions of the nervous system, musculoskeletal system, abdomen, thorax, and head and neck. It also contains several chapters on disease of the brain and spine, including inflammatory, infectious, neoplastic, and vascular diseases, alongside congenital and degenerative disorders.