Signaling in Telecommunication Networks

This is a self-contained book on the foundations and applications of optical and microwave technologies to telecommunication networks application, with an emphasis on access, local, road, cars, trains, vessels and airplanes, indoor and in-car data transmission as well as for long-distance fiber-systems and application in outer space and automation technology. The book provides a systematic discussion of physics/optics, electromagnetic wave theory, optical fibre technology, and the potential and limitations of optical and microwave transmission.

Effective project management tailored to the needs of the telecommunications industry «In our rapidly changing world, the information and communication technologies and services have an immense impact on virtually all aspects of our lives. . . . With his deep understanding of the telecommunication services, and his rich experiences in both standardization activities and teaching practice, [Dr. Sherif's] book provides a very clear analysis of development projects in telecommunication services. I believe the readers will find this book very useful and interesting.» —Houlin Zhao, Director, Telecommunication Standardization Bureau,International Telecommunication Union «Dr. Sherif's book is an important contribution to the project management literature. With the domination of the service economy in recent years, the book addresses the unique features of telecommunication services, a critical pillar of the service sector. Development projects in telecommunications require combining good knowledge of the fundamentals of project management with clear understanding of the complexities arising from fast-changing technology, deregulations, standards, accountability, and supply chain management difficulties. This book addresses the much-needed integrative approach very well.» —Tarek Khalil, President, International Association for Management of Technology (IAMOT) While there has been much written about project management, the vast majority of the literature focuses on industrial design and production. In Managing Projects in Telecommunication Services, Mostafa Hashem Sherif effectively demonstrates the unique requirements of projects in telecommunication services and, consequently, the benefits of an integrated approach to project management that is specifically tailored to the telecommunications industry. Managing Projects in Telecommunication Services draws from a wide range of disciplines, including organizational management, motivation, quality control, and software engineering. All the theory and practical guidance that an effective telecommunications project manager needs is provided. The text is divided into three main parts: Chapters 1 through 3 set forth the special characteristics of telecommunications projects, including technology life cycle, type of innovation, and project organization Chapters 4 through 10 cover the areas that the Project Management Institute has standardized in its publication A Guide to the Project Management Body of Knowledge (PMBOK® Guide), focusing on the issues specific to telecommunications. Chapters address scope, schedule and cost, information and communication, human resources, quality, vendor management, and risk Chapters 11 and 12 integrate and summarize all of the concepts for the planning and delivery of a project Chapters are loaded with examples and case studies, many from the author's personal experience, that demonstrate the benefits of good project management and the consequences of poor project management. Each chapter includes a summary of key points. References are also provided to facilitate further research and study. For project managers as well as students in telecommunications, this text is unsurpassed. It not only covers the theory and practice of effective project management, it also tailors its discussion specifically to the unique needs of the telecommunications industry. (PMBOK is a registered mark of the Project Management Institute, Inc.)

Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as: Autophagy Notch Pathway P13K/PTEN Signaling in Liver Diseases Sirtuins Hepcidin and Iron Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis Oxidative Stress and Signaling in the Liver. Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

Wnt signaling in Development and Disease: Molecular Mechanisms and Biological Functions reviews the core topics in Wnt signaling, from molecular pathway mechanisms to its role in embryogenesis, adult tissue homeostasis, and chronic disease. Written by a team of expert reviewers, the book provides clear and concise coverage of the core foundations of Wnt signaling before advancing to discussion of cutting-edge scientific research. Focused on the biological insights and current scientific questions of Wnt signaling, this book will be a comprehensive and definitive resource for a wide range of researchers and students in cell signaling, cell physiology, developmental biology, and biomedical engineering, as well as anyone interested in learning more about this important and complex protein network. • A definitive source of information on Wnt signaling and its role in development and disease, written by leaders in the field. • Explores the role of Wnt signaling in chronic disease such as melanoma, colorectal cancer, dementia, and psychiatric diseases • Reviews the complex processes of signal integration and regulation • Features broad discussion of Wnt signaling biology as well as detailed discussion of the pathway’s role in diseases and potential clinical applications.

Providing a comprehensive insight into cellular signaling processes in bacteria with a special focus on biotechnological implications, this is the first book to cover intercellular as well as intracellular signaling and its relevance for biofilm formation, host pathogen interactions, symbiotic relationships, and photo- and chemotaxis. In addition, it deals in detail with principal bacterial signaling mechanisms – making this a valuable resource for all advanced students in microbiology. Dr. Kramer is a world-renowned expert in intracellular signaling and its implications for biotechnology processes, while Dr. Jung is an expert on intercellular signaling and its relevance for biomedicine and agriculture.

A comprehensive summary of theoretical and practical developments in LTE Heterogeneous Networks The last decade has witnessed the proliferation of mobile broadband data and the trend is likely to increase in the coming years. Current cellular networks are ill equipped to deal with this surge in demand. To satisfy user demand and maximize profits, a new paradigm to operate networks is needed. Heterogeneous networks, that deploy an overlay of small cells with limited coverage and transmit power, over a macro coverage area is the solution by providing capacity and coverage where it is needed. This book presents a comprehensive overview of small cell based heterogeneous networks within the framework of 3GPP LTE-Advanced which is the major enabler of current and future heterogeneous networks. The book first establishes the basics of LTE standards 8 -10. Wherever relevant, the underlying theory of wireless communications is explained and the signaling and protocol aspects of LTE Releases 8-10 are presented. Next the book presents a systematic study of the inter cell interference (eICIC and FeICIC) mechanisms that have been standardized in LTE releases 10 and 11 to mitigate the interference arising in heterogeneous networks. From simple blank subframe design and implementation, the book discusses more advanced transceiver signal processing and carrier aggregation (CA) based mechanisms to improve performance. Besides data, control channel enhancements such as enhanced PDCCH (ePDCCH) are also discussed. Subsequently the book discusses the possibility of base stations being allowed to coordinate to manage interference. This technique, called CoMP, has the potential of vastly improving network performance. However several practical challenges first have to be overcome before this potential can be realized. The book presents the different CoMP categories introduced in LTE release 11, the required signal processing and the changes that were introduced in Release-11 for supporting CoMP. The book then presents the state of the art developments in heterogeneous networks that are currently taking place in 3GPP with the initiation of Release 12. A whole array of new technologies have been introduced such as dynamic switching of small cells, new carrier types with reduced control signaling, dynamic reconfiguration of TDD-LTE, joint configuration of TDD and FDD via carrier aggregation and lastly advanced MIMO signal processing with three dimensional beamforming. All these technologies will work in unison leading to efficient operations of small cells. The authors thus comprehensively summarize the advances in heterogeneous networks over the last couple of years as reflected in various LTE releases and then look ahead at what to expect in the future. Fully illustrated throughout and with an accompanying website including Matlab code for simulating heterogeneous networks, LTE channel models, and References to 3GPP specifications, contributions, and updates on recent standardization activities. The authors, being involved in LTE standardization, are well placed to give an excellent view on this topic, including valuable background and design rationale. A comprehensive summary of wireless communications theory and practical developments in LTE heterogeneous networks. Authors are experts in this field and are active members in standardization proceedings, enabling up-to-date coverage of current developments Multiple case studies explain network design optimization of various heterogeneous network deployments. Accompanying website includes Matlab code for simulating heterogeneous networks, LTE channel models, and References to 3GPP specifications, contributions, and updates on recent standardization activities Essential reading for Engineers and practitioners in wireless industry.

This extensively updated second edition of LTE Signaling, Troubleshooting and Performance Measurement describes the LTE signaling protocols and procedures for the third generation of mobile communications and beyond. It is one of the few books available that explain the LTE signaling messages, procedures and measurements down to the bit & byte level, and all trace examples are taken for a real lab and field trial traces. This book covers the crucial key performance indicators (KPI) to be measured during field trials and deployment phase of new LTE networks. It describes how statistic values can be aggregated and evaluated, and how the network can be optimized during the first stages of deployment, using dedicated examples to enhance understanding. Written by experts in the field of mobile communications, this book systematically describes the most recent LTE signaling procedures, explaining how to identify and troubleshoot abnormal network behavior and common failure causes, as well as describing the normal signaling procedures. This is a unique feature of the book, allowing readers to understand the root cause analysis of problems related to signaling procedures. This book will be especially useful for network operators and equipment manufacturers; engineers; technicians; network planners; developers; researchers; designers; testing personnel and project managers; consulting and training companies; standardization bodies.

International experts present innovative therapeutic strategies to treat cancer patients and prevent disease progression Extracellular Targeting of Cell Signaling in Cancer highlights innovative therapeutic strategies to treat cancer metastasis and prevent tumor progression. Currently, there are no drugs available to treat or prevent metastatic cancer other than non-selective, toxic chemotherapy. With contributions from an international panel of experts in the field, the book integrates diverse aspects of biochemistry, molecular biology, protein engineering, proteomics, cell biology, pharmacology, biophysics, structural biology, medicinal chemistry and drug development. A large class of proteins called kinases are enzymes required by cancer cells to grow, proliferate, and survive apoptosis (death) by the immune system. Two important kinases are MET and RON which are receptor tyrosine kinases (RTKs) that initiate cell signaling pathways outside the cell surface in response to extracellular ligands (growth factors.) Both kinases are oncogenes which are required by cancer cells to migrate away from the primary tumor, invade surrounding tissue and metastasize. MET and RON reside on both cancer cells and the support cells surrounding the tumor, called the microenvironment. MET and RON are activated by their particular ligands, the growth factors HGF and MSP, respectively. Blocking MET and RON kinase activation and downstream signaling is a promising therapeutic strategy for preventing tumor progression and metastasis. Written for cancer physicians and biologists as well as drug discovery and development teams in both industry and academia, this is the first book of its kind which explores novel approaches to inhibit MET and RON kinases other than traditional small molecule kinase inhibitors. These new strategies target key tumorigenic processes on the outside of the cell, such as growth factor activation by proteases. These unique strategies have promising potential as an improved alternative to kinase inhibitors, chemotherapy, or radiation treatment.

Wireless telecommunication systems generate a huge amount of interest. In the last two decades, these systems have experienced at least three major technological leaps, and it has become impossible to imagine how society was organized without them. In this book, we propose a macroscopic approach on wireless systems, and aim at answering key questions about power, data rates, multiple access, cellular engineering and access networks architectures. We present a series of solved problems, whose objective is to establish the main elements of a global link budget in several radiocommunications systems. Contents 1. Radio Propagation. 2. F/TDMA and GSM. 3. CDMA and UMTS. 4. OFDM and LTE. 5. MIMO and Beamforming. 6. UWB. 7. Synchronization. 8. Digital Communications Fundamentals. 9. Erlang B Tables. About the Authors Michel Terr? received his engineering degree from T?l?com SudParis, his phD in electronics and telecommunications from Conservatoire National des Arts et M?tiers (CNAM), and his habilitation to conduct researches from Paris XIII University. He is a full professor at Conservatoire National des Arts et M?tiers. He his responsabile of CNAM’s Master of Science in radiocommunicationssystems. Myl?ne Pischella received her engineering degree and her phD in electronics and telecommunications from T?l?com ParisTech. She is an associate professor at Conservatoire National des Arts et M?tiers (CNAM). Emmanuelle Vivier received her engineering degree from Institut Sup?rieur d’Electronique de Paris (ISEP) and her PhD in radiocommunications from Conservatoire National des Arts et M?tiers (CNAM). She is an associate professor at ISEP, where she is responsible of networks and telecommunications teaching majors.

Describes Information Hiding in communication networks, and highlights their important issues, challenges, trends, and applications. Highlights development trends and potential future directions of Information Hiding Introduces a new classification and taxonomy for modern data hiding techniques Presents different types of network steganography mechanisms Introduces several example applications of information hiding in communication networks including some recent covert communication techniques in popular Internet services