Simulation of Transport in Nanodevices

Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no longer possible for a human theorist to integrate all of the available information. Instead, computer technologies must now be used to perform this integration. This book brings together contributions from many different fields to summarize the current status of computer-assisted modelling of biological processes. The initial chapters deal with fundamental developments in hardware, software and mathematics that underlie current approaches to biological modelling. Next, different approaches to collating data on gene structure and function are presented. These databases form a vital resource for any investigator trying to construct an integrated picture of particular biological systems. Cell signalling systems form a particularly complicated aspect of all cellular function and are important both in the understanding of basic cellular processes and in selecting targets for drugs. Recent approaches to integrating data on cell signalling into computer models are covered. Further chapters build on these approaches to show how computerized models of intact cells can be developed. Finally, approaches to the computer modelling of whole organs such as the heart are presented. The role of computer modelling in drug design is the subject of the final chapter and is also touched on throughout the discussions.

This book provides a comprehensive view of geographical modeling. It first establishes the foundations of geographical modeling, covering such concepts as structure, organization, system, topologies, as well as the concept of time. Next, it tackles the use of computer tools for dynamic model building and presents several models applied to various themes, such as urban growth, natural risks, as well as political themes. Finally, a general model of the geographic agents system (GAS), which can be used as a basis for the construction of a model-building platform for dynamic spatial models is presented.

Principles of Flight Simulation is a comprehensive guide to flight simulator design, covering the modelling, algorithms and software which underpin flight simulation. The book covers the mathematical modelling and software which underpin flight simulation. The detailed equations of motion used to model aircraft dynamics are developed and then applied to the simulation of flight control systems and navigation systems. Real-time computer graphics algorithms are developed to implement aircraft displays and visual systems, covering OpenGL and OpenSceneGraph. The book also covers techniques used in motion platform development, the design of instructor stations and validation and qualification of simulator systems. An exceptional feature of Principles of Flight Simulation is access to a complete suite of software (www.wiley.com/go/allerton) to enable experienced engineers to develop their own flight simulator – something that should be well within the capability of many university engineering departments and research organisations. Based on C code modules from an actual flight simulator developed by the author, along with lecture material from lecture series given by the author at Cranfield University and the University of Sheffield Brings together mathematical modeling, computer graphics, real-time software, flight control systems, avionics and simulator validation into one of the faster growing application areas in engineering Features full colour plates of images and photographs. Principles of Flight Simulation will appeal to senior and postgraduate students of system dynamics, flight control systems, avionics and computer graphics, as well as engineers in related disciplines covering mechanical, electrical and computer systems engineering needing to develop simulation facilities.

Filling a gap in the literature and all set to become the standard in this field, this monograph begins with a look at computational viscoelastic fluid mechanics and studies of turbulent flows of dilute polymer solutions. It then goes on discuss simulations of nanocomposites, polymerization kinetics, computational approaches for polymers and modeling polyelectrolytes. Further sections deal with tire optimization, irreversible phenomena in polymers, the hydrodynamics of artificial and bacterial flagella as well as modeling and simulation in liquid crystals. The result is invaluable reading for polymer and theoretical chemists, chemists in industry, materials scientists and plastics technologists.

Explores wide-ranging applications of modeling and simulation techniques that allow readers to conduct research and ask «What if??» Principles of Modeling and Simulation: A Multidisciplinary Approach is the first book to provide an introduction to modeling and simulation techniques across diverse areas of study. Numerous researchers from the fields of social science, engineering, computer science, and business have collaborated on this work to explore the multifaceted uses of computational modeling while illustrating their applications in common spreadsheets. The book is organized into three succinct parts: Principles of Modeling and Simulation provides a brief history of modeling and simulation, outlines its many functions, and explores the advantages and disadvantages of using models in problem solving. Two major reasons to employ modeling and simulation are illustrated through the study of a specific problem in conjunction with the use of related applications, thus gaining insight into complex concepts. Theoretical Underpinnings examines various modeling techniques and introduces readers to two significant simulation concepts: discrete event simulation and simulation of continuous systems. This section details the two primary methods in which humans interface with simulations, and it also distinguishes the meaning, importance, and significance of verification and validation. Practical Domains delves into specific topics related to transportation, business, medicine, social science, and enterprise decision support. The challenges of modeling and simulation are discussed, along with advanced applied principles of modeling and simulation such as representation techniques, integration into the application infrastructure, and emerging technologies. With its accessible style and wealth of real-world examples, Principles of Modeling and Simulation: A Multidisciplinary Approach is a valuable book for modeling and simulation courses at the upper-undergraduate and graduate levels. It is also an indispensable reference for researchers and practitioners working in statistics, mathematics, engineering, computer science, economics, and the social sciences who would like to further develop their understanding and knowledge of the field.

This book offers a comprehensive review of the state-of-the-art in innovative Beyond-CMOS nanodevices for developing novel functionalities, logic and memories dedicated to researchers, engineers and students. It particularly focuses on the interest of nanostructures and nanodevices (nanowires, small slope switches, 2D layers, nanostructured materials, etc.) for advanced More than Moore (RF-nanosensors-energy harvesters, on-chip electronic cooling, etc.) and Beyond-CMOS logic and memories applications.

This book offers a comprehensive review of the state-of-the-art in innovative Beyond-CMOS nanodevices for developing novel functionalities, logic and memories dedicated to researchers, engineers and students. The book will particularly focus on the interest of nanostructures and nanodevices (nanowires, small slope switches, 2D layers, nanostructured materials, etc.) for advanced More than Moore (RF-nanosensors-energy harvesters, on-chip electronic cooling, etc.) and Beyond-CMOS logic and memories applications.

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

The definite guide to the theory, knowledge, technical expertise, and ethical considerations that define the M&S profession From traffic control to disaster management, supply chain analysis to military logistics, healthcare management to new drug discovery, modeling and simulation (M&S) has become an essential tool for solving countless real-world problems. M&S professionals are now indispensable to how things get done across virtually every aspect of modern life. This makes it all the more surprising that, until now, no effort has been made to systematically codify the core theory, knowledge, and technical expertise needed to succeed as an M&S professional. This book brings together contributions from experts at the leading edge of the modeling and simulation profession, worldwide, who share their priceless insights into issues which are fundamental to professional success and career development in this critically important field. Running as a common thread throughout the book is an emphasis on several key aspects of the profession, including the essential body of knowledge underlying the M&S profession; the technical discipline of M&S; the ethical standards that should guide professional conduct; and the economic and commercial challenges today’s M&S professionals face. • Demonstrates applications of M&S tools and techniques in a variety of fields—such as engineering, operations research, and cyber environments—with over 500 types of simulations • Highlights professional and academic aspects of the field, including preferred programming languages, professional academic and certification programs, and key international societies • Shows why M&S professionals must be fully versed in the theory, concepts, and tools needed to address the challenges of cyber environments The Profession of Modeling and Simulation is a valuable resource for M&S practitioners, developers, and researchers working in industry and government. Simulation professionals, including administrators, managers, technologists, faculty members, and scholars within the physical sciences, life sciences, and engineering fields will find it highly useful, as will students planning to pursue a career in the M&S profession. “ …nearly three dozen experts in Modeling and Simulation (M&S) come together to make a compelling case for the recognition of M&S as a profession… Important reading for anyone seeking to elevate the standing of this vital field.” Alfred (Al) Grasso, President & CEO, The MITRE Corporation Andreas Tolk, PhD, is Technology Integrator for the Modeling, Simulation, Experimentation, and Analytics Division of The MITRE Corporation, an adjunct professor in the Department of Engineering Management and Systems Engineering and the Department for Modeling, Simulation, and Visualization Engineering at Old Dominion University, and an SCS fellow. Tuncer ?ren, PhD, is Professor Emeritus of Computer Science at the University of Ottawa. He is an SCS fellow and an inductee to SCS Modeling and Simulation Hall of Fame. His research interests include advancing methodologies, ethics, body of knowledge, and terminology of modeling and simulation.

Systems engineering is the design of a complex interconnection of many elements (a system) to maximize a specific measure of system performance. It consists of two parts: modeling, in which each element of the system and its performance criteria are described; and optimization in which adjustable elements are tailored to allow peak performance. Systems engineering is applied to vast numbers of problems in industry and the military. An example of systems engineering at work is the control of the timing of thousands of city traffic lights to maximize traffic flow. The complex and intricate field of electronics and computers is perfectly suited for systems engineering analysis and in turn, advances in communications and computer technology have made more advanced systems engineering problems solvable. Thus, the two areas fed off of one another. This book is a basic introduction to the use of models and methods in the engineering design of systems. It is aimed at students as well as practicing engineers. The concept of the «systems of systems» is discussed extensively, after a critical comparison of the different definitions and a range of various practical illustrations. It also provides key answers as to what a system of systems is and how its complexity can be mastered.