Statistics for Microarrays

Praise for the Second Edition «Statistics for Research has other fine qualities besides superior organization. The examples and the statistical methods are laid out with unusual clarity by the simple device of using special formats for each. The book was written with great care and is extremely user-friendly.»—The UMAP Journal Although the goals and procedures of statistical research have changed little since the Second Edition of Statistics for Research was published, the almost universal availability of personal computers and statistical computing application packages have made it possible for today's statisticians to do more in less time than ever before. The Third Edition of this bestselling text reflects how the changes in the computing environment have transformed the way statistical analyses are performed today. Based on extensive input from university statistics departments throughout the country, the authors have made several important and timely revisions, including: Additional material on probability appears early in the text New sections on odds ratios, ratio and difference estimations, repeated measure analysis, and logistic regression New examples and exercises, many from the field of the health sciences Printouts of computer analyses on all complex procedures An accompanying Web site illustrating how to use SAS® and JMP® for all procedures The text features the most commonly used statistical techniques for the analysis of research data. As in the earlier editions, emphasis is placed on how to select the proper statistical procedure and how to interpret results. Whenever possible, to avoid using the computer as a «black box» that performs a mysterious process on the data, actual computational procedures are also given. A must for scientists who analyze data, professionals and researchers who need a self-teaching text, and graduate students in statistical methods, Statistics for Research, Third Edition brings the methodology up to date in a very practical and accessible way.

This practical text is an essential source of information for those wanting to know how to deal with the variability that exists in every engineering situation. Using typical engineering data, it presents the basic statistical methods that are relevant, in simple numerical terms. In addition, statistical terminology is translated into basic English. In the past, a lack of communication between engineers and statisticians, coupled with poor practical skills in quality management and statistical engineering, was damaging to products and to the economy. The disastrous consequence of setting tight tolerances without regard to the statistical aspect of process data is demonstrated. This book offers a solution, bridging the gap between statistical science and engineering technology to ensure that the engineers of today are better equipped to serve the manufacturing industry. Inside, you will find coverage on: the nature of variability, describing the use of formulae to pin down sources of variation; engineering design, research and development, demonstrating the methods that help prevent costly mistakes in the early stages of a new product; production, discussing the use of control charts, and; management and training, including directing and controlling the quality function. The Engineering section of the index identifies the role of engineering technology in the service of industrial quality management. The Statistics section identifies points in the text where statistical terminology is used in an explanatory context. Engineers working on the design and manufacturing of new products find this book invaluable as it develops a statistical method by which they can anticipate and resolve quality problems before launching into production. This book appeals to students in all areas of engineering and also managers concerned with the quality of manufactured products. Academic engineers can use this text to teach their students basic practical skills in quality management and statistical engineering, without getting involved in the complex mathematical theory of probability on which statistical science is dependent.

An up-to-date version of the complete, self-contained introduction to matrix analysis theory and practice Providing accessible and in-depth coverage of the most common matrix methods now used in statistical applications, Matrix Analysis for Statistics, Third Edition features an easy-to-follow theorem/proof format. Featuring smooth transitions between topical coverage, the author carefully justifies the step-by-step process of the most common matrix methods now used in statistical applications, including eigenvalues and eigenvectors; the Moore-Penrose inverse; matrix differentiation; and the distribution of quadratic forms. An ideal introduction to matrix analysis theory and practice, Matrix Analysis for Statistics, Third Edition features: • New chapter or section coverage on inequalities, oblique projections, and antieigenvalues and antieigenvectors • Additional problems and chapter-end practice exercises at the end of each chapter • Extensive examples that are familiar and easy to understand • Self-contained chapters for flexibility in topic choice • Applications of matrix methods in least squares regression and the analyses of mean vectors and covariance matrices Matrix Analysis for Statistics, Third Edition is an ideal textbook for upper-undergraduate and graduate-level courses on matrix methods, multivariate analysis, and linear models. The book is also an excellent reference for research professionals in applied statistics. James R. Schott, PhD, is Professor in the Department of Statistics at the University of Central Florida. He has published numerous journal articles in the area of multivariate analysis. Dr. Schott’s research interests include multivariate analysis, analysis of covariance and correlation matrices, and dimensionality reduction techniques.

Winner of the 2013 DeGroot Prize. A state-of-the-art presentation of spatio-temporal processes, bridging classic ideas with modern hierarchical statistical modeling concepts and the latest computational methods Noel Cressie and Christopher K. Wikle, are also winners of the 2011 PROSE Award in the Mathematics category, for the book “Statistics for Spatio-Temporal Data” (2011), published by John Wiley and Sons. (The PROSE awards, for Professional and Scholarly Excellence, are given by the Association of American Publishers, the national trade association of the US book publishing industry.) Statistics for Spatio-Temporal Data has now been reprinted with small corrections to the text and the bibliography. The overall content and pagination of the new printing remains the same; the difference comes in the form of corrections to typographical errors, editing of incomplete and missing references, and some updated spatio-temporal interpretations. From understanding environmental processes and climate trends to developing new technologies for mapping public-health data and the spread of invasive-species, there is a high demand for statistical analyses of data that take spatial, temporal, and spatio-temporal information into account. Statistics for Spatio-Temporal Data presents a systematic approach to key quantitative techniques that incorporate the latest advances in statistical computing as well as hierarchical, particularly Bayesian, statistical modeling, with an emphasis on dynamical spatio-temporal models. Cressie and Wikle supply a unique presentation that incorporates ideas from the areas of time series and spatial statistics as well as stochastic processes. Beginning with separate treatments of temporal data and spatial data, the book combines these concepts to discuss spatio-temporal statistical methods for understanding complex processes. Topics of coverage include: Exploratory methods for spatio-temporal data, including visualization, spectral analysis, empirical orthogonal function analysis, and LISAs Spatio-temporal covariance functions, spatio-temporal kriging, and time series of spatial processes Development of hierarchical dynamical spatio-temporal models (DSTMs), with discussion of linear and nonlinear DSTMs and computational algorithms for their implementation Quantifying and exploring spatio-temporal variability in scientific applications, including case studies based on real-world environmental data Throughout the book, interesting applications demonstrate the relevance of the presented concepts. Vivid, full-color graphics emphasize the visual nature of the topic, and a related FTP site contains supplementary material. Statistics for Spatio-Temporal Data is an excellent book for a graduate-level course on spatio-temporal statistics. It is also a valuable reference for researchers and practitioners in the fields of applied mathematics, engineering, and the environmental and health sciences.

A thoroughly updated guide to matrix algebra and it uses in statistical analysis and features SAS®, MATLAB®, and R throughout This Second Edition addresses matrix algebra that is useful in the statistical analysis of data as well as within statistics as a whole. The material is presented in an explanatory style rather than a formal theorem-proof format and is self-contained. Featuring numerous applied illustrations, numerical examples, and exercises, the book has been updated to include the use of SAS, MATLAB, and R for the execution of matrix computations. In addition, Andr? I. Khuri, who has extensive research and teaching experience in the field, joins this new edition as co-author. The Second Edition also: Contains new coverage on vector spaces and linear transformations and discusses computational aspects of matrices Covers the analysis of balanced linear models using direct products of matrices Analyzes multiresponse linear models where several responses can be of interest Includes extensive use of SAS, MATLAB, and R throughout Contains over 400 examples and exercises to reinforce understanding along with select solutions Includes plentiful new illustrations depicting the importance of geometry as well as historical interludes Matrix Algebra Useful for Statistics, Second Edition is an ideal textbook for advanced undergraduate and first-year graduate level courses in statistics and other related disciplines. The book is also appropriate as a reference for independent readers who use statistics and wish to improve their knowledge of matrix algebra. THE LATE SHAYLE R. SEARLE, PHD, was professor emeritus of biometry at Cornell University. He was the author of Linear Models for Unbalanced Data and Linear Models and co-author of Generalized, Linear, and Mixed Models, Second Edition, Matrix Algebra for Applied Economics, and Variance Components, all published by Wiley. Dr. Searle received the Alexander von Humboldt Senior Scientist Award, and he was an honorary fellow of the Royal Society of New Zealand. ANDR? I. KHURI, PHD, is Professor Emeritus of Statistics at the University of Florida. He is the author of Advanced Calculus with Applications in Statistics, Second Edition and co-author of Statistical Tests for Mixed Linear Models, all published by Wiley. Dr. Khuri is a member of numerous academic associations, among them the American Statistical Association and the Institute of Mathematical Statistics.

A comprehensive look at how probability and statistics is applied to the investment process Finance has become increasingly more quantitative, drawing on techniques in probability and statistics that many finance practitioners have not had exposure to before. In order to keep up, you need a firm understanding of this discipline. Probability and Statistics for Finance addresses this issue by showing you how to apply quantitative methods to portfolios, and in all matter of your practices, in a clear, concise manner. Informative and accessible, this guide starts off with the basics and builds to an intermediate level of mastery. • Outlines an array of topics in probability and statistics and how to apply them in the world of finance • Includes detailed discussions of descriptive statistics, basic probability theory, inductive statistics, and multivariate analysis • Offers real-world illustrations of the issues addressed throughout the text The authors cover a wide range of topics in this book, which can be used by all finance professionals as well as students aspiring to enter the field of finance.

A core statistics text that emphasizes logical inquiry, not math Basic Statistics for Social Research teaches core general statistical concepts and methods that all social science majors must master to understand (and do) social research. Its use of mathematics and theory are deliberately limited, as the authors focus on the use of concepts and tools of statistics in the analysis of social science data, rather than on the mathematical and computational aspects. Research questions and applications are taken from a wide variety of subfields in sociology, and each chapter is organized around one or more general ideas that are explained at its beginning and then applied in increasing detail in the body of the text. Each chapter contains instructive features to aid students in understanding and mastering the various statistical approaches presented in the book, including: Learning objectives Check quizzes after many sections and an answer key at the end of the chapter Summary Key terms End-of-chapter exercises SPSS exercises (in select chapters) Ancillary materials for both the student and the instructor are available and include a test bank for instructors and downloadable video tutorials for students.

The first statistics guide focussing on practical application to process control design and maintenance Statistics for Process Control Engineers is the only guide to statistics written by and for process control professionals. It takes a wholly practical approach to the subject. Statistics are applied throughout the life of a process control scheme – from assessing its economic benefit, designing inferential properties, identifying dynamic models, monitoring performance and diagnosing faults. This book addresses all of these areas and more. The book begins with an overview of various statistical applications in the field of process control, followed by discussions of data characteristics, probability functions, data presentation, sample size, significance testing and commonly used mathematical functions. It then shows how to select and fit a distribution to data, before moving on to the application of regression analysis and data reconciliation. The book is extensively illustrated throughout with line drawings, tables and equations, and features numerous worked examples. In addition, two appendices include the data used in the examples and an exhaustive catalogue of statistical distributions. The data and a simple-to-use software tool are available for download. The reader can thus reproduce all of the examples and then extend the same statistical techniques to real problems. Takes a back-to-basics approach with a focus on techniques that have immediate, practical, problem-solving applications for practicing engineers, as well as engineering students Shows how to avoid the many common errors made by the industry in applying statistics to process control Describes not only the well-known statistical distributions but also demonstrates the advantages of applying the large number that are less well-known Inspires engineers to identify new applications of statistical techniques to the design and support of control schemes Provides a deeper understanding of services and products which control engineers are often tasked with assessing This book is a valuable professional resource for engineers working in the global process industry and engineering companies, as well as students of engineering. It will be of great interest to those in the oil and gas, chemical, pulp and paper, water purification, pharmaceuticals and power generation industries, as well as for design engineers, instrument engineers and process technical support.

Categorical Statistics for CommunicationResearch presents scholars with a discipline-specific guide to categorical data analysis. The text blends necessary background information and formulas for statistical procedures with data analyses illustrating techniques such as log- linear modeling and logistic regression analysis. Provides techniques for analyzing categorical data from a communication studies perspective Provides an accessible presentation of techniques for analyzing categorical data for communication scholars and other social scientists working at the advanced undergraduate and graduate teaching levels Illustrated with examples from different types of communication research such as health, political and sports communication and entertainment Includes exercises at the end of each chapter and a companion website containing exercise answers and chapter-by-chapter PowerPoint slides

The book introduces to the reader a number of cutting edge statistical methods which can e used for the analysis of genomic, proteomic and metabolomic data sets. In particular in the field of systems biology, researchers are trying to analyze as many data as possible in a given biological system (such as a cell or an organ). The appropriate statistical evaluation of these large scale data is critical for the correct interpretation and different experimental approaches require different approaches for the statistical analysis of these data. This book is written by biostatisticians and mathematicians but aimed as a valuable guide for the experimental researcher as well computational biologists who often lack an appropriate background in statistical analysis.