The Structure of the Nucleon

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function.  Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.

Structure from Motion with Multi View Stereo provides hyperscale landform models using images acquired from standard compact cameras and a network of ground control points. The technique is not limited in temporal frequency and can provide point cloud data comparable in density and accuracy to those generated by terrestrial and airborne laser scanning at a fraction of the cost. It therefore offers exciting opportunities to characterise surface topography in unprecedented detail and, with multi-temporal data, to detect elevation, position and volumetric changes that are symptomatic of earth surface processes. This book firstly places Structure from Motion in the context of other digital surveying methods and details the Structure from Motion workflow including available software packages and assessments of uncertainty and accuracy. It then critically reviews current usage of Structure from Motion in the geosciences, provides a synthesis of recent validation studies and looks to the future by highlighting opportunities arising from developments in allied disciplines. This book will appeal to academics, students and industry professionals because it balances technical knowledge of the Structure from Motion workflow with practical guidelines for image acquisition, image processing and data quality assessment and includes case studies that have been contributed by experts from around the world.

Intended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to choose the correct analytical method for each problem, saving both time and resources. Special emphasis is placed on NMR and its application to absolute configuration determination and the analysis of molecular interactions. Adopting a practical point of view, the author team from academia and industry guarantees both solid methodology and applications essential for structure determination, equipping experts as well as newcomers with the tools to solve any structural problem.

Although synthetic fullerenes have only been around for a few years, there are thousands of scientific articles dealing with them. This is the first monograph in the field and thus represents a vital source of information summarizing the most important and fundamental aspects of the organic and organometallic chemistry of the fullerenes. The book is logically arranged so that information is easy to retrieve, and the style lends itself to effortless reading and to learning more about the chemical properties of a family of molecules that constitute new building blocks for novel architectures in the ever-expanding universe of synthetic chemistry. Belongs on the shelves of university libraries as well as those of chemists interested in the art and science of structure and property manipulation by synthesis.

The Handbook of the History of English is a collection of articles written by leading specialists in the field that focus on the theoretical issues behind the facts of the changing English language. organizes the theoretical issues behind the facts of the changing English language innovatively and applies recent insights to old problems surveys the history of English from the perspective of structural developments in areas such as phonology, prosody, morphology, syntax, semantics, language variation, and dialectology offers readers a comprehensive overview of the various theoretical perspectives available to the study of the history of English and sets new objectives for further research

An in-depth look at the nature of market making and exchanges From theory to practicalities, this is a comprehensive, up-to-date handbook and reference on how markets work and the nuances of trading. It includes a CD with an interactive trading simulation. Robert A. Schwartz, PhD (New York, NY), is Marvin M. Speiser Professor of Finance and University Distinguished Professor in the Zicklin School of Business, Baruch College, CUNY. Reto Francioni, PhD (Zurich, Switzerland), is President and Chairman of the Board of SWX, the Swiss Stock Exchange, and former co-CEO of Consors Discount Broker AG, Nuremberg.

This book traces the evolution of theory of structures and strength of materials – the development of the geometrical thinking of the Renaissance to become the fundamental engineering science discipline rooted in classical mechanics. Starting with the strength experiments of Leonardo da Vinci and Galileo, the author examines the emergence of individual structural analysis methods and their formation into theory of structures in the 19th century. For the first time, a book of this kind outlines the development from classical theory of structures to the structural mechanics and computational mechanics of the 20th century. In doing so, the author has managed to bring alive the differences between the players with respect to their engineering and scientific profiles and personalities, and to create an understanding for the social context. Brief insights into common methods of analysis, backed up by historical details, help the reader gain an understanding of the history of structural mechanics from the standpoint of modern engineering practice. A total of 175 brief biographies of important personalities in civil and structural engineering as well as structural mechanics plus an extensive bibliography round off this work.