Analysis of Survey Data

This book is the first to focus on the application of mathematical networks for analyzing microarray data. This method goes well beyond the standard clustering methods traditionally used. From the contents: * Understanding and Preprocessing Microarray Data * Clustering of Microarray Data * Reconstruction of the Yeast Cell Cycle by Partial Correlations of Higher Order * Bilayer Verification Algorithm * Probabilistic Boolean Networks as Models for Gene Regulation * Estimating Transcriptional Regulatory Networks by a Bayesian Network * Analysis of Therapeutic Compound Effects * Statistical Methods for Inference of Genetic Networks and Regulatory Modules * Identification of Genetic Networks by Structural Equations * Predicting Functional Modules Using Microarray and Protein Interaction Data * Integrating Results from Literature Mining and Microarray Experiments to Infer Gene Networks The book is for both, scientists using the technique as well as those developing new analysis techniques.

Statistical science’s first coordinated manual of methods for analyzing ordered categorical data, now fully revised and updated, continues to present applications and case studies in fields as diverse as sociology, public health, ecology, marketing, and pharmacy. Analysis of Ordinal Categorical Data, Second Edition provides an introduction to basic descriptive and inferential methods for categorical data, giving thorough coverage of new developments and recent methods. Special emphasis is placed on interpretation and application of methods including an integrated comparison of the available strategies for analyzing ordinal data. Practitioners of statistics in government, industry (particularly pharmaceutical), and academia will want this new edition.

The first part of this book is devoted to methods seeking relevant dimensions of data. The variables thus obtained provide a synthetic description which often results in a graphical representation of the data. After a general presentation of the discriminating analysis, the second part is devoted to clustering methods which constitute another method, often complementary to the methods described in the first part, to synthesize and to analyze the data. The book concludes by examining the links existing between data mining and data analysis.

The statistical analysis of cost-effectiveness data is becoming increasingly important within health and medical research. Statistical Analysis of Cost-Effectiveness Data provides a practical book that synthesises the huge amount of research that has taken place in the area over the last two decades. Comprising an up-to-date overview of the statistical analysis of cost-effectiveness data, the book is supported by numerous worked examples from the author’s own experience. It has been written in a style suitable for medical statisticians and health care professionals alike. Key features include: an overview of statistical methods used in the analysis of cost-effectiveness data. coverage of Bayesian methodology. illustrated throughout by worked examples using real data. suitability for health care professionals with limited statistical knowledge. discussion of software used for data analysis. An essential reference for biostatisticians and health economists engaged in cost-effectiveness analysis of health-care interventions, both in academia and industry. Also of interest to graduate students of biostatistics, public health and economics.

The field of high-throughput genetic experimentation is evolving rapidly, with the advent of new technologies and new venues for data mining. Bayesian methods play a role central to the future of data and knowledge integration in the field of Bioinformatics. This book is devoted exclusively to Bayesian methods of analysis for applications to high-throughput gene expression data, exploring the relevant methods that are changing Bioinformatics. Case studies, illustrating Bayesian analyses of public gene expression data, provide the backdrop for students to develop analytical skills, while the more experienced readers will find the review of advanced methods challenging and attainable. This book: Introduces the fundamentals in Bayesian methods of analysis for applications to high-throughput gene expression data. Provides an extensive review of Bayesian analysis and advanced topics for Bioinformatics, including examples that extensively detail the necessary applications. Accompanied by website featuring datasets, exercises and solutions. Bayesian Analysis of Gene Expression Data offers a unique introduction to both Bayesian analysis and gene expression, aimed at graduate students in Statistics, Biomedical Engineers, Computer Scientists, Biostatisticians, Statistical Geneticists, Computational Biologists, applied Mathematicians and Medical consultants working in genomics. Bioinformatics researchers from many fields will find much value in this book.

Modeling and Analysis of Compositional Data presents a practical and comprehensive introduction to the analysis of compositional data along with numerous examples to illustrate both theory and application of each method. Based upon short courses delivered by the authors, it provides a complete and current compendium of fundamental to advanced methodologies along with exercises at the end of each chapter to improve understanding, as well as data and a solutions manual which is available on an accompanying website. Complementing Pawlowsky-Glahn’s earlier collective text that provides an overview of the state-of-the-art in this field, Modeling and Analysis of Compositional Data fills a gap in the literature for a much-needed manual for teaching, self learning or consulting.

Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on: * Image analysis * Experiment design * Automated analysis, integrated analysis, and systems biology * Interpretation of results Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.

With the advent of the Web along with the unprecedented amount of information available in electronic format, conceptual data analysis is more useful and practical than ever, because this technology addresses important limitations of the systems that currently support users in their quest for information. Concept Data Analysis: Theory & Applications is the first book that provides a comprehensive treatment of the full range of algorithms available for conceptual data analysis, spanning creation, maintenance, display and manipulation of concept lattices. The accompanying website allows you to gain a greater understanding of the principles covered in the book through actively working on the topics discussed. The three main areas explored are interactive mining of documents or collections of documents (including Web documents), automatic text ranking, and rule mining from structured data. The potentials of conceptual data analysis in the application areas being considered are further illustrated by two detailed case studies. Concept Data Analysis: Theory & Applications is essential for researchers active in information processing and management and industry practitioners who are interested in creating a commercial product for conceptual data analysis or developing content management applications.

With the advent of computers, very large datasets have become routine. Standard statistical methods don’t have the power or flexibility to analyse these efficiently, and extract the required knowledge. An alternative approach is to summarize a large dataset in such a way that the resulting summary dataset is of a manageable size and yet retains as much of the knowledge in the original dataset as possible. One consequence of this is that the data may no longer be formatted as single values, but be represented by lists, intervals, distributions, etc. The summarized data have their own internal structure, which must be taken into account in any analysis. This text presents a unified account of symbolic data, how they arise, and how they are structured. The reader is introduced to symbolic analytic methods described in the consistent statistical framework required to carry out such a summary and subsequent analysis. Presents a detailed overview of the methods and applications of symbolic data analysis. Includes numerous real examples, taken from a variety of application areas, ranging from health and social sciences, to economics and computing. Features exercises at the end of each chapter, enabling the reader to develop their understanding of the theory. Provides a supplementary website featuring links to download the SODAS software developed exclusively for symbolic data analysis, data sets, and further material. Primarily aimed at statisticians and data analysts, Symbolic Data Analysis is also ideal for scientists working on problems involving large volumes of data from a range of disciplines, including computer science, health and the social sciences. There is also much of use to graduate students of statistical data analysis courses.

Amstat News asked three review editors to rate their top five favorite books in the September 2003 issue. Categorical Data Analysis was among those chosen. A valuable new edition of a standard reference «A 'must-have' book for anyone expecting to do research and/or applications in categorical data analysis.» –Statistics in Medicine on Categorical Data Analysis, First Edition The use of statistical methods for categorical data has increased dramatically, particularly for applications in the biomedical and social sciences. Responding to new developments in the field as well as to the needs of a new generation of professionals and students, this new edition of the classic Categorical Data Analysis offers a comprehensive introduction to the most important methods for categorical data analysis. Designed for statisticians and biostatisticians as well as scientists and graduate students practicing statistics, Categorical Data Analysis, Second Edition summarizes the latest methods for univariate and correlated multivariate categorical responses. Readers will find a unified generalized linear models approach that connects logistic regression and Poisson and negative binomial regression for discrete data with normal regression for continuous data. Adding to the value in the new edition is coverage of: Three new chapters on methods for repeated measurement and other forms of clustered categorical data, including marginal models and associated generalized estimating equations (GEE) methods, and mixed models with random effects Stronger emphasis on logistic regression modeling of binary and multicategory data An appendix showing the use of SAS for conducting nearly all analyses in the book Prescriptions for how ordinal variables should be treated differently than nominal variables Discussion of exact small-sample procedures More than 100 analyses of real data sets to illustrate application of the methods, and more than 600 exercises An Instructor's Manual presenting detailed solutions to all the problems in the book is available from the Wiley editorial department.