Applied Biostatistics for the Health Sciences

Accessible to medicine- and/or public policy-related audiences, as well as most statisticians. Emphasis on outliers is discussed by way of detection and treatment. Resampling statistics software is incorporated throughout. Motivating applications are presented in light of honest theory. Plentiful exercises are sprinkled throughout.

A modern and practical guide to the essential concepts and ideas for analyzing data with missing observations in the field of biostatistics With an emphasis on hands-on applications, Applied Missing Data Analysis in the Health Sciences outlines the various modern statistical methods for the analysis of missing data. The authors acknowledge the limitations of established techniques and provide newly-developed methods with concrete applications in areas such as causal inference methods and the field of diagnostic medicine. Organized by types of data, chapter coverage begins with an overall introduction to the existence and limitations of missing data and continues into traditional techniques for missing data inference, including likelihood-based, weighted GEE, multiple imputation, and Bayesian methods. The book’s subsequently covers cross-sectional, longitudinal, hierarchical, survival data. In addition, Applied Missing Data Analysis in the Health Sciences features: Multiple data sets that can be replicated using the SAS®, Stata®, R, and WinBUGS software packages Numerous examples of case studies in the field of biostatistics to illustrate real-world scenarios and demonstrate applications of discussed methodologies Detailed appendices to guide readers through the use of the presented data in various software environments Applied Missing Data Analysis in the Health Sciences is an excellent textbook for upper-undergraduate and graduate-level biostatistics courses as well as an ideal resource for health science researchers and applied statisticians.

An application-based introduction to the statistical analysis of spatially referenced health data Sparked by the growing interest in statistical methods for the analysis of spatially referenced data in the field of public health, Applied Spatial Statistics for Public Health Data fills the need for an introductory, application-oriented text on this timely subject. Written for practicing public health researchers as well as graduate students in related fields, the text provides a thorough introduction to basic concepts and methods in applied spatial statistics as well as a detailed treatment of some of the more recent methods in spatial statistics useful for public health studies that have not been previously covered elsewhere. Assuming minimal knowledge of spatial statistics, the authors provide important statistical approaches for assessing such questions as: Are newly occurring cases of a disease «clustered» in space? Do the cases cluster around suspected sources of increased risk, such as toxic waste sites or other environmental hazards? How do we take monitored pollution concentrations measured at specific locations and interpolate them to locations where no measurements were taken? How do we quantify associations between local disease rates and local exposures? After reviewing traditional statistical methods used in public health research, the text provides an overview of the basic features of spatial data, illustrates various geographic mapping and visualization tools, and describes the sources of publicly available spatial data that might be useful in public health applications.

Biostatistics for Oral Healthcare offers students, practitioners and instructors alike a comprehensive guide to mastering biostatistics and their application to oral healthcare. Drawing on situations and methods from dentistry and oral healthcare, this book provides a thorough treatment of statistical concepts in order to promote in-depth and correct comprehension, supported throughout by technical discussion and a multitude of practical examples.

A comprehensive introduction to behavioral and social science research methods in the health sciences Understanding and Conducting Research in the Health Sciences is designed to develop and facilitate the ability to conduct research and understand the practical value of designing, conducting, interpreting, and reporting behavioral and social science research findings in the health science and medical fields. The book provides complete coverage of the process behind these research methods, including information-gathering, decision formation, and results presentation. Examining the application of behavioral and social science research methodologies within the health sciences, the book focuses on implementing and developing relevant research questions, collecting and managing data, and communicating various research perspectives. An essential book for readers looking to possess an understanding of all aspects of conducting research in the health science field, Understanding and Conducting Research in the Health Sciences features: Various research designs that are appropriate for use in the health sciences, including single-participant, multi-group, longitudinal, correlational, and experimental designs Step-by-step coverage of single-factor and multifactor studies as well as single-subject and nonexperimental methods Accessible chapter explanations, real-world examples, and numerous illustrations throughout Guidance regarding how to write about research within the formatting styles of the American Medical Association and the American Psychological Association The book is an excellent educational resource for healthcare and health service practitioners and researchers who are interested in conducting and understanding behavioral and social science research done within the health sciences arena. The book is also a useful resource for students taking courses in the fields of medicine, public health, epidemiology, biostatistics, and the health sciences.

A fundamental and straightforward guide to using and understanding statistical concepts in medical research Designed specifically for healthcare practitioners who need to understand basic biostatistics but do not have much time to spare, The Essentials of Biostatistics for Physicians, Nurses and Clinicians presents important statistical methods used in today's biomedical research and provides insight on their appropriate application. Rather than provide detailed mathematics for each of these methods, the book emphasizes what healthcare practitioners need to know to interpret and incorporate the latest biomedical research into their practices. The author draws from his own experience developing and teaching biostatistics courses for physicians and nurses, offering a presentation that is non-technical and accessible. The book begins with a basic introduction to the relationship between biostatistics and medical research, asking the question «why study statistics?,» while also exploring the significance of statisitcal methods in medical literature and clinical trials research. Subsequent chapters explore key topics, including: Correlation, regression, and logistic regression Diagnostics Estimating means and proportions Normal distribution and the central limit theorem Sampling from populations Contingency tables Meta-analysis Nonparametric methods Survival analysis Throughout the book, statistical methods that are often utilized in biomedical research are outlined, including repeated measures analysis of variance, hazard ratios, contingency tables, log rank tests, bioequivalence, cross-over designs, selection bias, and group sequential methods. Exercise sets at the end of each chapter allow readers to test their comprehension of the presented concepts and techniques. The Essentials of Biostatistics for Physicians, Nurses, and Clinicians is an excellent reference for doctors, nurses, and other practicing clinicians in the fields of medicine, public health, pharmacy, and the life sciences who need to understand and apply statistical methods in their everyday work. It also serves as a suitable supplement for courses on biostatistics at the upper-undergraduate and graduate levels.

Chemistry: An Introduction for Medical and Health Sciences provides students and practitioners with a clear, readable introduction to the chemical terms and concepts that are relevant to their study and practice. Assuming little prior knowledge of the subject the book describes and explains the chemistry underlying many of the most commonly prescribed drugs and medicines. It also includes information on chemical aspects of digestion and nutrition, oxidation, radioactivity and an overview of how chemicals fight disease. Excellent pedagogy including learning objectives, diagnostic tests and questions in each chapter and a comprehensive glossary Experienced author team with many years experience of teaching chemistry to non-chemists

An introduction to the physical principles of spectroscopy and their applications to the biological sciences Advances in such fields as proteomics and genomics place new demands on students and professionals to be able to apply quantitative concepts to the biological phenomena that they are studying. Spectroscopy for the Biological Sciences provides students and professionals with a working knowledge of the physical chemical aspects of spectroscopy, along with their applications to important biological problems. Designed as a companion to Professor Hammes's Thermodynamics and Kinetics for the Biological Sciences, this approachable yet thorough text covers the basic principles of spectroscopy, including: * Fundamentals of spectroscopy * Electronic spectra * Circular dichroism and optical rotary dispersion * Vibration in macromolecules (IR, Raman, etc.) * Magnetic resonance * X-ray crystallography * Mass spectrometry With a minimum of mathematics and a strong focus on applications to biology, this book will prepare current and future professionals to better understand the quantitative interpretation of biological phenomena and to utilize these tools in their work.

A collection of highly valuable statistical and computational approaches designed for developing powerful methods to analyze large-scale high-throughput data derived from studies of complex diseases. Such diseases include cancer and cardiovascular disease, and constitute the major health challenges in industrialized countries. They are characterized by the systems properties of gene networks and their interrelations, instead of individual genes, whose malfunctioning manifests in pathological phenotypes, thus making the analysis of the resulting large data sets particularly challenging. This is why novel approaches are needed to tackle this problem efficiently on a systems level. Written by computational biologists and biostatisticians, this book is an invaluable resource for a large number of researchers working on basic but also applied aspects of biomedical data analysis emphasizing the pathway level.