Blue Biotechnology. Production and Use of Marine Molecules

Biotechnology can deliver complex flavors both as fermentation products and single constituents. Recent developments in transgenic research have spawned numerous studies in the use of metabolic engineering of biosynthetic pathways to produce high-value secondary metabolites that can enhance the flavors of food products. Biotechnology is also playing an increasingly important role in the breeding of food crops for enhanced flavor. This book provides a unique overview of the current state of the art of flavor production through biotechnology, examining the principles and current methods of producing flavors from plants and other organisms. Chapters are included on plant tissue culture, genetic engineering of plants for flavor improvement and genetic engineering of bacteria and fungi for flavor improvement of fermented beverages and dairy products. The book is directed at food scientists and technologists in the food and flavour industries as well as academics and ingredients suppliers.

Anaerobic biotechnology is a cost-effective and sustainable means of treating waste and wastewaters that couples treatment processes with the reclamation of useful by-products and renewable biofuels. This means of treating municipal, agricultural, and industrial wastes allows waste products to be converted to value-added products such as biofuels, biofertilizers, and other chemicals. Anaerobic Biotechnology for Bioenergy Production: Principles and Applications provides the reader with basic principles of anaerobic processes alongside practical uses of anaerobic biotechnology options. This book will be a valuable reference to any professional currently considering or working with anaerobic biotechnology options.

A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas, this reference: Provides an overview of biotechnology used in the drug development process Covers extensive applications, plus regulations and validation methods Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers, toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality assurance/assessment/control managers, biotechnology technicians, and others in the biotech industry.

Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Oil and gas still power the bulk of our world, from automobiles and the power plants that supply electricity to our homes and businesses, to jet fuel, plastics, and many other products that enrich our lives. With the relatively recent development of hydraulic fracturing («fracking»), multilateral, directional, and underbalanced drilling, and enhanced oil recovery, oil and gas production is more important and efficient than ever before. Along with these advancements, as with any new engineering process or technology, come challenges, many of them environmental. More than just a text that outlines the environmental challenges of oil and gas production that have always been there, such as gas migration and corrosion, this groundbreaking new volume takes on the most up-to-date processes and technologies involved in this field. Filled with dozens of case studies and examples, the authors, two of the most well-known and respected petroleum engineers in the world, have outlined all of the major environmental aspects of oil and gas production and how to navigate them, achieving a more efficient, effective, and profitable operation. This groundbreaking volume is a must-have for any petroleum engineer working in the field, and for students and faculty in petroleum engineering departments worldwide.

The science and practice of pig production has changed rapidly over recent decades; new husbandry practices, new understandings of growth, reproduction and health, new appreciations of welfare and environmental impact, new nutritional approaches, and modern reproductive and genetic techniques have all come into being, together with the emergence of new health challenges. Now in its third edition, this long established reference book on the management, breeding, feeding, nutrition, health and welfare of pigs has been fully revised to provide clear and current information on both the practical and scientific aspects of the pig industry. With the help of a new panel of international experts and a senior editor, the overall structure now contains input from international centres across Europe and North America. This edition includes: Updated versions of existing chapters; Completely revised and new sections on: Pig meat and carcass quality, Reproduction, The maintenance of health, Nutritional value of protein and amino acids in feed stuffs, Value of fats and oils in pig diets, Product marketing, Environmental management, Simulation modelling; Input from international authorities; Many tables, diagrams, photographs and figures.

This brand new Annual Plant Reviews volume is the second edition of the highly successful and well-received Functions of Plant Secondary Metabolites and their Exploitation in Biotechnology (Annual Plant Reviews, Volume 3). This exciting new volume provides an up-to-date survey of the functions of plant secondary metabolites, their modes of action and their use in pharmacology as molecular probes, in medicine as therapeutic agents, and in agriculture as biorational pesticides. The possibilities to produce valuable natural products in plant cell and tissue culture and even in recombinant microorganisms are also reviewed. This carefully compiled new edition brings together chapters from some of the world’s leading experts in plant secondary metabolites. Completely revised and brought right up to date with much new information, this volume is an essential purchase for advanced students, researchers and professionals in biochemistry, physiology, molecular biology, genetics, plant sciences, agriculture, medicine, pharmacology and pharmacy, working in the academic and industrial sectors, including those working in the pesticide and pharmaceutical industries. Libraries in all universities and research establishments where these subjects are studied and taught will need copies of this excellent volume on their shelves. A companion volume Annual Plant Reviews Volume 40, Biochemistryof Plant Secondary Metabolism, Second Edition, Edited by M. Wink, is also available.

While the choices of microbial and eukaryotic expression systems for production of recombinant proteins are many, most researchers in academic and industrial settings do not have ready access to pertinent biological and technical information since it is normally scattered throughout the scientific literature. This book closes the gap by providing information on the general biology of the host organism, a description of the expression platform, a methodological section – with strains, genetic elements, vectors and special methods, where applicable – as well as examples of proteins produced with the respective platform. The systems thus described are well balanced by the inclusion of three prokaryotes (two Gram-negatives and one Gram-positive), four yeasts, two filamentous fungi and two higher eukaryotic cell systems – mammalian and plant cells. Throughout, the book provides valuable practical and theoretical information on the criteria and schemes for selecting the appropriate expression platform, the possibility and practicality of a universal expression vector, and on comparative industrial-scale fermentation, with the production of a recombinant Hepatitis B vaccine chosen as an industrial example. With a foreword by Herbert P. Schweizer, Colorado State University, USA: «As a whole, this book is a valuable and overdue resource for a varied audience. It is a practical guide for academic and industrial researchers who are confronted with the design of the most suitable expression platform for their favorite protein for technical or pharmaceutical purposes. In addition, the book is also a valuable study resource for professors and students in the fields of applied biology and biotechnology.»

This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.

Organic Meat Production and Processing describes the challenges of production, processing and food safety of organic meat. The editors and international collection of authors explore the trends in organic meats and how the meat industry is impacted. Commencing with chapters on the economics, market and regulatory aspects of organic meats, coverage then extends to management issues for organically raised and processed meat animals. Processing, sensory and human health aspects are covered in detail, as are the incidences of foodborne pathogens in organic beef, swine, poultry and other organic meat species. The book concludes by describing pre-harvest control measures for assuring the safety of organic meats. Organic Meat Production and Processing serves as a unique resource for fully understanding the current and potential issues associated with organic meats.