Computational Intelligence and Pattern Analysis in Biology Informatics

A comprehensive overview of high-performance pattern recognition techniques and approaches to Computational Molecular Biology This book surveys the developments of techniques and approaches on pattern recognition related to Computational Molecular Biology. Providing a broad coverage of the field, the authors cover fundamental and technical information on these techniques and approaches, as well as discussing their related problems. The text consists of twenty nine chapters, organized into seven parts: Pattern Recognition in Sequences, Pattern Recognition in Secondary Structures, Pattern Recognition in Tertiary Structures, Pattern Recognition in Quaternary Structures, Pattern Recognition in Microarrays, Pattern Recognition in Phylogenetic Trees, and Pattern Recognition in Biological Networks. Surveys the development of techniques and approaches on pattern recognition in biomolecular data Discusses pattern recognition in primary, secondary, tertiary and quaternary structures, as well as microarrays, phylogenetic trees and biological networks Includes case studies and examples to further illustrate the concepts discussed in the book Pattern Recognition in Computational Molecular Biology: Techniques and Approaches is a reference for practitioners and professional researches in Computer Science, Life Science, and Mathematics. This book also serves as a supplementary reading for graduate students and young researches interested in Computational Molecular Biology.

Combining biology, computer science, mathematics, and statistics, the field of bioinformatics has become a hot new discipline with profound impacts on all aspects of biology and industrial application. Now, Computational Intelligence in Bioinformatics offers an introduction to the topic, covering the most relevant and popular CI methods, while also encouraging the implementation of these methods to readers' research.

Computational Intelligence: An Introduction, Second Edition offers an in-depth exploration into the adaptive mechanisms that enable intelligent behaviour in complex and changing environments. The main focus of this text is centred on the computational modelling of biological and natural intelligent systems, encompassing swarm intelligence, fuzzy systems, artificial neutral networks, artificial immune systems and evolutionary computation. Engelbrecht provides readers with a wide knowledge of Computational Intelligence (CI) paradigms and algorithms; inviting readers to implement and problem solve real-world, complex problems within the CI development framework. This implementation framework will enable readers to tackle new problems without any difficulty through a single Java class as part of the CI library. Key features of this second edition include: A tutorial, hands-on based presentation of the material. State-of-the-art coverage of the most recent developments in computational intelligence with more elaborate discussions on intelligence and artificial intelligence (AI). New discussion of Darwinian evolution versus Lamarckian evolution, also including swarm robotics, hybrid systems and artificial immune systems. A section on how to perform empirical studies; topics including statistical analysis of stochastic algorithms, and an open source library of CI algorithms. Tables, illustrations, graphs, examples, assignments, Java code implementing the algorithms, and a complete CI implementation and experimental framework. Computational Intelligence: An Introduction, Second Edition is essential reading for third and fourth year undergraduate and postgraduate students studying CI. The first edition has been prescribed by a number of overseas universities and is thus a valuable teaching tool. In addition, it will also be a useful resource for researchers in Computational Intelligence and Artificial Intelligence, as well as engineers, statisticians, operational researchers, and bioinformaticians with an interest in applying AI or CI to solve problems in their domains. Check out http://www.ci.cs.up.ac.za for examples, assignments and Java code implementing the algorithms.

Computational Intelligence: Synergies of Fuzzy Logic, Neural Networks and Evolutionary Computing presents an introduction to some of the cutting edge technological paradigms under the umbrella of computational intelligence. Computational intelligence schemes are investigated with the development of a suitable framework for fuzzy logic, neural networks and evolutionary computing, neuro-fuzzy systems, evolutionary-fuzzy systems and evolutionary neural systems. Applications to linear and non-linear systems are discussed with examples. Key features: Covers all the aspects of fuzzy, neural and evolutionary approaches with worked out examples, MATLAB® exercises and applications in each chapter Presents the synergies of technologies of computational intelligence such as evolutionary fuzzy neural fuzzy and evolutionary neural systems Considers real world problems in the domain of systems modelling, control and optimization Contains a foreword written by Lotfi Zadeh Computational Intelligence: Synergies of Fuzzy Logic, Neural Networks and Evolutionary Computing is an ideal text for final year undergraduate, postgraduate and research students in electrical, control, computer, industrial and manufacturing engineering.

The rough and fuzzy set approaches presented here open up many new frontiers for continued research and development Computational Intelligence and Feature Selection provides readers with the background and fundamental ideas behind Feature Selection (FS), with an emphasis on techniques based on rough and fuzzy sets. For readers who are less familiar with the subject, the book begins with an introduction to fuzzy set theory and fuzzy-rough set theory. Building on this foundation, the book provides: A critical review of FS methods, with particular emphasis on their current limitations Program files implementing major algorithms, together with the necessary instructions and datasets, available on a related Web site Coverage of the background and fundamental ideas behind FS A systematic presentation of the leading methods reviewed in a consistent algorithmic framework Real-world applications with worked examples that illustrate the power and efficacy of the FS approaches covered An investigation of the associated areas of FS, including rule induction and clustering methods using hybridizations of fuzzy and rough set theories Computational Intelligence and Feature Selection is an ideal resource for advanced undergraduates, postgraduates, researchers, and professional engineers. However, its straightforward presentation of the underlying concepts makes the book meaningful to specialists and nonspecialists alike.

This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles have failed, in offering a wide range of information from the introductory fundamentals right up to the latest, most advanced levels of study.

Revealing suspension geometry design methods in unique detail, John Dixon shows how suspension properties such as bump steer, roll steer, bump camber, compliance steer and roll centres are analysed and controlled by the professional engineer. He emphasizes the physical understanding of suspension parameters in three dimensions and methods of their calculation, using examples, programs and discussion of computational problems. The analytical and design approach taken is a combination of qualitative explanation, for physical understanding, with algebraic analysis of linear and non-linear coefficients, and detailed discussion of computer simulations and related programming methods. Includes a detailed and comprehensive history of suspension and steering system design, fully illustrated with a wealth of diagrams Explains suspension characteristics and suspension geometry coefficients, providing a unique and in-depth understanding of suspension design not found elsewhere. Describes how to obtain desired coefficients and the limitations of particular suspension types, with essential information for suspension designers, chassis technicians and anyone else with an interest in suspension characteristics and vehicle dynamics. Discusses the use of computers in suspension geometry analysis, with programming techniques and examples of suspension solution, including advanced discussion of three-dimensional computational geometry applied to suspension design. Explains in detail the direct and iterative solutions of suspension geometry.

The only single, up-to-date source for Grid issues in bioinformatics and biology Bioinformatics is fast emerging as an important discipline for academic research and industrial applications, creating a need for the use of Grid computing techniques for large-scale distributed applications. This book successfully presents Grid algorithms and their real-world applications, provides details on modern and ongoing research, and explores software frameworks that integrate bioinformatics and computational biology. Additional coverage includes: * Bio-ontology and data mining * Data visualization * DNA assembly, clustering, and mapping * Molecular evolution and phylogeny * Gene expression and micro-arrays * Molecular modeling and simulation * Sequence search and alignment * Protein structure prediction * Grid infrastructure, middleware, and tools for bio data Grid Computing for Bioinformatics and Computational Biology is an indispensable resource for professionals in several research and development communities including bioinformatics, computational biology, Grid computing, data mining, and more. It also serves as an ideal textbook for undergraduate- and graduate-level courses in bioinformatics and Grid computing.

Concise Encyclopaedia of Bioinformatics and Computational Biology, 2nd Edition is a fully revised and updated version of this acclaimed resource. The book provides definitions and often explanations of over 1000 words, phrases and concepts relating to this fast-moving and exciting field, offering a convenient, one-stop summary of the core knowledge in the area. This second edition is an invaluable resource for students, researchers and academics.

Provides an in-depth and even treatment of the three pillars of computational intelligence and how they relate to one another This book covers the three fundamental topics that form the basis of computational intelligence: neural networks, fuzzy systems, and evolutionary computation. The text focuses on inspiration, design, theory, and practical aspects of implementing procedures to solve real-world problems. While other books in the three fields that comprise computational intelligence are written by specialists in one discipline, this book is co-written by current former Editor-in-Chief of IEEE Transactions on Neural Networks and Learning Systems, a former Editor-in-Chief of IEEE Transactions on Fuzzy Systems, and the founding Editor-in-Chief of IEEE Transactions on Evolutionary Computation. The coverage across the three topics is both uniform and consistent in style and notation. Discusses single-layer and multilayer neural networks, radial-basis function networks, and recurrent neural networks Covers fuzzy set theory, fuzzy relations, fuzzy logic interference, fuzzy clustering and classification, fuzzy measures and fuzzy integrals Examines evolutionary optimization, evolutionary learning and problem solving, and collective intelligence Includes end-of-chapter practice problems that will help readers apply methods and techniques to real-world problems Fundamentals of Computational intelligence is written for advanced undergraduates, graduate students, and practitioners in electrical and computer engineering, computer science, and other engineering disciplines.