Engineering Principles in Biotechnology

Principles in Microbiome Engineering Provides an overview of the techniques and applications insight into the complex composition and interactions of microbiomes Microbiomes, the communities of microorganisms that inhabit specific ecosystems or organisms, can be engineered to modify the structure of microbiota and reestablish ecological balance. In recent years, a better understanding of microbial composition and host-microbe interactions has led to the development of new applications for improving human health and increasing agricultural productivity and quality. Principles in Microbiome Engineering introduces readers to the tools and applications involved in manipulating the composition of a microbial community to improve the function of an eco-system. Covering a range of key topics, this up-to-date volume discusses current research in areas such as microbiome-based therapeutics for human diseases, crop plant breeding, animal husbandry, soil engineering, food and beverage applications, and more. Divided into three sections, the text first describes the critical roles of systems biology, synthetic biology, computer modelling, and machine learning in microbiome engineering. Next, the volume explores various state-of-the-art applications, including cancer immunotherapy and prevention of diseases associated with the human microbiome, followed by a concluding section offering perspectives on the future of microbiome engineering and potential applications. Introduces a variety of applications of microbiome engineering in the fields of medicine, agriculture, and food and beverage products Presents current research into the complex interactions and relationships between microbiomes and biotic and abiotic elements of their environments Examines the use of technologies such as Artificial Intelligence (AI), Machine Learning (ML), and Big Data analytics to advance understanding of microbiomes Discusses the engineering of microbiomes to address human health conditions such as neuro psychiatric disorders and autoimmune and inflammatory diseases Edited and authored by leading researchers in the rapidly evolving field, Principles in Microbiome Engineering is an essential resource for biotechnologists, biochemists, microbiologists, pharmacologists, and practitioners working in the biotechnology and pharmaceutical industries.

As rapid advances in biotechnology occur, there is a need for a pedagogical tool to aid current students and laboratory professionals in biotechnological methods; Methods in Biotechnology is an invaluable resource for those students and professionals. Methods in Biotechnology engages the reader by implementing an active learning approach, provided advanced study questions, as well as pre- and post-lab questions for each lab protocol. These self-directed study sections encourage the reader to not just perform experiments but to engage with the material on a higher level, utilizing critical thinking and troubleshooting skills. This text is broken into three sections based on level – Methods in Biotechnology, Advanced Methods in Biotechnology I, and Advanced Methods in Biotechnology II. Each section contains 14-22 lab exercises, with instructor notes in appendices as well as an answer guide as a part of the book companion site. This text will be an excellent resource for both students and laboratory professionals in the biotechnology field.

A very broad range of professionals are using immunoassay technology daily to analyze genetically engineered (GE) crops and related areas, and many of these professionals are completely new to this technology. There is a great need for users to have a book containing technical and practical guidance, and describing limitations and pitfalls of applying immunoassay in agricultural biotechnology. This book focuses on the application of immunoassays to GE plants and related areas. A group of international experts from government agencies, academics and industries, who have many years of related experience, contribute high quality chapters in their areas of expertise. This book covers topics including principles of immunoassay, antibody engineering in AgBiotech, current technologies (formats, kit development, manufacturing and quality control), method validation, applications in trait discovery and product development, applications in grain products and food processing, applications in environmental monitoring, automation and high throughput, reference materials, data interpretation and source of error, and future perspectives and challenges. In addition, to meet the practical needs for a variety of readers from different backgrounds, methods and protocols are included as well.

Throughout history, human beings have sought ways to enhance the flavor of the foods they eat. In the 21st century, biotechnology plays an important role in the flavor improvement of many types of foods. This book covers many of the biotechnological approaches currently being applied to flavor enhancement. The contribution of microbial metabolism to flavor development in fermented beverages and dairy products has been exploited for thousands of years, but the recent availability of whole genome sequences of the yeasts and bacteria involved in these processes is stimulating targeted approaches to flavor enhancement. Chapters discuss recent developments in the flavor modification of wine, beer, and dairy products through the manipulation of the microbial species involved. Biotechnological approaches to the production of specific flavor molecules in microbes and plant tissue cultures, and the challenges that have been encountered, are also covered, along with the metabolic engineering of food crops for flavor enhancement – also a current area of research. Biotechnology is also being applied to crop breeding through marker-assisted selection for important traits, including flavor, and the book looks at the application of the biotechnological approach to breeding for enhanced flavor in rice, apple, and basil. These techniques are subject to governmental regulation, and this is addressed in a dedicated chapter. This updated second edition features five brand new chapters, and the topics covered in the book will be of interest to those in the flavor and food industries as well as to academic researchers interested in flavors.

Enables chemical engineering students to bridge theory and practice Integrating scientific principles with practical engineering experience, this text enables readers to master the fundamentals of chemical processing and apply their knowledge of such topics as material and energy balances, transport phenomena, reactor design, and separations across a broad range of chemical industries. The author skillfully guides readers step by step through the execution of both chemical process analysis and equipment design. Principles of Chemical Engineering Practice is divided into two sections: the Macroscopic View and the Microscopic View. The Macroscopic View examines equipment design and behavior from the vantage point of inlet and outlet conditions. The Microscopic View is focused on the equipment interior resulting from conditions prevailing at the equipment boundaries. As readers progress through the text, they'll learn to master such chemical engineering operations and equipment as: Separators to divide a mixture into parts with desirable concentrations Reactors to produce chemicals with needed properties Pressure changers to create favorable equilibrium and rate conditions Temperature changers and heat exchangers to regulate and change the temperature of process streams Throughout the book, the author sets forth examples that refer to a detailed simulation of a process for the manufacture of acrylic acid that provides a unifying thread for equipment sizing in context. The manufacture of hexyl glucoside provides a thread for process design and synthesis. Presenting basic thermodynamics, Principles of Chemical Engineering Practice enables students in chemical engineering and related disciplines to master and apply the fundamentals and to proceed to more advanced studies in chemical engineering.

Environmental Engineering: Principles and Practice is written for advanced undergraduate and first-semester graduate courses in the subject. The text provides a clear and concise understanding of the major topic areas facing environmental professionals. For each topic, the theoretical principles are introduced, followed by numerous examples illustrating the process design approach. Practical, methodical and functional, this exciting new text provides knowledge and background, as well as opportunities for application, through problems and examples that facilitate understanding. Students pursuing the civil and environmental engineering curriculum will fi nd this book accessible and will benefit from the emphasis on practical application. The text will also be of interest to students of chemical and mechanical engineering, where several environmental concepts are of interest, especially those on water and wastewater treatment, air pollution, and sustainability. Practicing engineers will find this book a valuable resource, since it covers the major environmental topics and provides numerous step-by-step examples to facilitate learning and problem-solving. Environmental Engineering: Principles and Practice offers all the major topics, with a focus upon: • a robust problem-solving scheme introducing statistical analysis; • example problems with both US and SI units; • water and wastewater design; • sustainability; • public health. There is also a companion website with illustrations, problems and solutions.

Environmental Engineering: Principles and Practice is written for advanced undergraduate and first-semester graduate courses in the subject. The text provides a clear and concise understanding of the major topic areas facing environmental professionals. For each topic, the theoretical principles are introduced, followed by numerous examples illustrating the process design approach. Practical, methodical and functional, this exciting new text provides knowledge and background, as well as opportunities for application, through problems and examples that facilitate understanding. Students pursuing the civil and environmental engineering curriculum will fi nd this book accessible and will benefit from the emphasis on practical application. The text will also be of interest to students of chemical and mechanical engineering, where several environmental concepts are of interest, especially those on water and wastewater treatment, air pollution, and sustainability. Practicing engineers will find this book a valuable resource, since it covers the major environmental topics and provides numerous step-by-step examples to facilitate learning and problem-solving. Environmental Engineering: Principles and Practice offers all the major topics, with a focus upon: • a robust problem-solving scheme introducing statistical analysis; • example problems with both US and SI units; • water and wastewater design; • sustainability; • public health. There is also a companion website with illustrations, problems and solutions.

Here, the world's top experts impart their knowledge and experience, many in print for the first time. By considering developing country markets, this book is the first truly global guide to technology transfer, helping companies all around the world to avoid costly mistakes in product development and to recover investments quickly. Individual sections treat trade-related aspects of intellectual property rights, technology transfer in health and healthcare as well as in agriculture and the environment.

Dr. Abdelhamid Elaissari, internationally respected author and researcher, reports on and analyzes a broad range of important findings from new studies on the use of colloidal nanoparticles in biomedical, food, and environmental diagnostics and analyses. Throughout the presentation, the book uses a blend of classical tools, including optical microscopy, atomic force microscopy, microsystems, and microfluidics, to help you take full advantage of colloidal nanoparticles for your own research and applications.