Freeze-Drying

This completely updated and enlarged third edition of the classic text adopts a practical approach to describe the fundamentals of freeze-drying, backed by many explanatory examples. Following an introduction to the fundamentals, the book goes on to discuss process and plant automation as well as methods to transfer pilot plant qualifications and process data to production. An entire section is devoted to a large range of different pharmaceutical, biological, and medical products. New to this edition are chapters on antibodies, freeze-dry microscopy, TEMPRIS, microwave freeze-drying, spray freeze-drying, and PAT. Their many years of experience in freeze-drying enable the authors to supply valuable criteria for the selection of laboratory, pilot and production plants, discussing the advantages, drawbacks and limitations of different plant designs. Alongside guidelines for the evaluation and qualification of plants and processes, the author also includes a troubleshooting section.

Filling a gap in the literature, this is the first book to focus on the fabrication of functional porous materials by using ice templating and freeze drying. Comprehensive in its scope, the volume covers such techniques as the fabrication of porous polymers, porous ceramics, biomimic strong composites, carbon nanostructured materials, nanomedicine, porous nanostructures by freeze drying of colloidal or nanoparticle suspensions, and porous materials by combining ice templating and other techniques. In addition, applications for each type of material are also discussed. Of great benefit to those working in the freeze-drying field and researchers in porous materials, materials chemistry, engineering, and the use of such materials for various applications, both in academia and industry.

Comprehensively covers conventional and novel drying systems and applications, while keeping a focus on the fundamentals of drying phenomena. Presents detailed thermodynamic and heat/mass transfer analyses in a reader-friendly and easy-to-follow approach Includes case studies, illustrative examples and problems Presents experimental and computational approaches Includes comprehensive information identifying the roles of flow and heat transfer mechanisms on the drying phenomena Considers industrial applications, corresponding criterion, complications, prospects, etc. Discusses novel drying technologies, the corresponding research platforms and potential solutions

Handbook of Drying for Dairy Products is a complete guide to the field’s principles and applications, with an emphasis on best practices for the creation and preservation of dairy-based food ingredients. Details the techniques and results of drum drying, spray drying, freeze drying, spray-freeze drying, and hybrid drying Contains the most up-to-date research for optimizing the drying of dairy, as well as computer modelling options Addresses the effect of different drying techniques on the nutritional profile of dairy products Provides essential information for dairy science academics as well as technologists active in the dairy industry

A practical guide for ensuring a defect-free coating and drying process For professionals in the coating and drying industry, the world is a demanding place. New, technically complex products such as fuel cell membranes, thin film batteries, solar cells, and RFID chips require coatings of extreme precision. With the bar raised so high, understanding how to troubleshoot and eliminate defects on a coating line is an essential skill for all personnel. Coating and Drying Defects, Second Edition provides manufacturing and quality control personnel, equipment operators and supervisors, and plant engineers and scientists with the full complement of proven tools and techniques for detecting, defining, and eliminating coating defects and operating problems, and for ensuring that they do not recur. Updating the valuable contents of the first edition, this practical Second Edition: Describes all major processes for coating and drying of continuous film on sheets or webs Covers technologies that have been recently developed to prevent defect formation and improve operating procedures Provides a rational framework within which to assess and analyze virtually any defect that may arise Offers step-by-step guidelines for conducting every phase of the troubleshooting process, including defect prevention Going beyond simply describing a disparate set of troubleshooting techniques, this unique guide arms readers with a systematic, nonmathematical methodology encompassing the entire coating operation, becoming an indispensable resource for manufacturing and quality-control personnel as well as plant engineers, polymer scientists, surface scientists, organic chemists, and coating scientists.

A comprehensive approach to selecting and understanding drying equipment for chemical and mechanical engineers A detailed reference of interest for engineers and energy specialists working in the process industry field, Drying in the Process Industry investigates the current state of the art of today's industrial drying practices, examines the factors influencing drying's high costs in both equipment and energy consumption, and summarizes key elements for keeping drying operations under budget and performing at peak capacity safely while respecting the environment. Extensive coverage of dryer basics as well as essential procedures concerning the selection of industrial dryers—such as how to gather results of relevant laboratory measurements, carry out small-scale tests, and correctly size equipment—help to inform readers on criteria for generating scalable specifications that greatly assist buying decisions. Drying in the Process Industry: Takes a practical approach to drying equipment, from an author with four decades in the industry Describes a diverse array of drying equipment (convective, like flash, spray, fluid-bed, and rotary; contact, like paddle and steam; radiation) from an engineer's perspective Provides quick and ready access to drying technologies with references to more detailed literature Treats drying in the context of the entire production process True of all process facilities where drying plays an important role, such as those in the chemical, pharmaceutical, plastics, and food industries, the purchase of improper industrial drying equipment can significantly affect a manufacturer's economic bottom line. With the guidance offered in this book, engineers will be able to confidently choose industrial drying equipment that increases profits, runs efficiently, and optimally suits their needs.

The five-volume series provides a comprehensive overview of all important aspects of drying technology like computational tools at different scales (Volume 1), modern experimental and analytical techniques (Volume 2), product quality and formulation (Volume 3), energy savings (Volume 4) and process intensification (Volume 5). Based on high-level cutting-edge results contributed by internationally recognized experts in the various treated fields, this book series is the ultimate reference in the area of industrial drying. Located at the intersection of the two main approaches in modern chemical engineering, product engineering and process systems engineering, the series aims at bringing theory into practice in order to improve the quality of high-value dried products, save energy, and cut the costs of drying processes. Volume 5 is dedicated to process intensification by more efficient distribution and flow of the drying medium, foaming, controlled freezing, and the application of superheated steam, infrared radiation, microwaves, power ultrasound and pulsed electric fields. Process efficiency is treated in conjunction with the quality of sensitive products, such as foods, for a variety of hybrid and combined drying processes. Other Volumes and Sets: Volume 1 – Modern Drying Technology, Computational Tools at Different Scales Volume 1: Diverse model types for the drying of products and the design of drying processes (short-cut methods, homogenized, pore network, and continuous thermo-mechanical approaches) are treated, along with computational fluid dynamics, population balances, and process systems simulation tools. Emphasis is put on scale transitions. Volume 2 – Modern Drying Technology: Experimental Techniques Volume 2: Comprises experimental methods used in various industries and in research in order to design and control drying processes, measure moisture and moisture distributions, characterize particulate material and the internal micro-structure of dried products, and investigate the behavior of particle systems in drying equipment. Key topics include acoustic levitation, near-infrared spectral imaging, magnetic resonance imaging, X-ray tomography, and positron emission tracking. Volume 3 – Modern Drying Technology: Product Quality and Formulation Volume 3: Discusses how desired properties of foods, biomaterials, active pharmaceutical ingredients, and fragile aerogels can be preserved during drying, and how spray drying and spray fluidized bed processes can be used for particle formation and formulation. Methods for monitoring product quality, such as process analytical technology, and modeling tools, such as Monte Carlo simulations, discrete particle modeling and neural networks, are presented with real examples from industry and academia. Volume 4 – Modern Drying Technology: Energy Savings Volume 4: Deals with the reduction of energy demand in various drying processes and areas, highlighting the following topics: Energy analysis of dryers, efficient solid-liquid separation techniques, osmotic dehydration, heat pump assisted drying, zeolite usage, solar drying, drying and heat treatment for solid wood and other biomass sources, and sludge thermal processing. Available in print as 5 Volume Set or as indi

The five-volume series provides a comprehensive overview of all important aspects of drying technology like computational tools at different scales (Volume 1), modern experimental and analytical techniques (Volume 2), product quality and formulation (Volume 3), energy savings (Volume 4) and process intensification (Volume 5). Based on high-level cutting-edge results contributed by internationally recognized experts in the various treated fields, this book series is the ultimate reference in the area of industrial drying. Located at the intersection of the two main approaches in modern chemical engineering, product engineering and process systems engineering, the series aims at bringing theory into practice in order to improve the quality of high-value dried products, save energy, and cut the costs of drying processes. Volume 4 deals with the reduction of energy demand in various drying processes and areas, highlighting the following topics: Energy analysis of dryers, efficient solid-liquid separation techniques, osmotic dehydration, heat pump assisted drying, zeolite usage, solar drying, drying and heat treatment for solid wood and other biomass sources, and sludge thermal processing. Other Volumes and Sets: Volume 1 – Modern Drying Technology, Computational Tools at Different Scales Volume 1: Diverse model types for the drying of products and the design of drying processes (short-cut methods, homogenized, pore network, and continuous thermo-mechanical approaches) are treated, along with computational fluid dynamics, population balances, and process systems simulation tools. Emphasis is put on scale transitions. Volume 2 – Modern Drying Technology: Experimental Techniques Volume 2: Comprises experimental methods used in various industries and in research in order to design and control drying processes, measure moisture and moisture distributions, characterize particulate material and the internal micro-structure of dried products, and investigate the behavior of particle systems in drying equipment. Key topics include acoustic levitation, near-infrared spectral imaging, magnetic resonance imaging, X-ray tomography, and positron emission tracking. Volume 3 – Modern Drying Technology: Product Quality and Formulation Volume 3: Discusses how desired properties of foods, biomaterials, active pharmaceutical ingredients, and fragile aerogels can be preserved during drying, and how spray drying and spray fluidized bed processes can be used for particle formation and formulation. Methods for monitoring product quality, such as process analytical technology, and modeling tools, such as Monte Carlo simulations, discrete particle modeling and neural networks, are presented with real examples from industry and academia. Volume 5 – Process Intensification Volume 5: Dedicated to process intensification by more efficient distribution and flow of the drying medium, foaming, controlled freezing, and the application of superheated steam, infrared radiation, microwaves, power ultrasound and pulsed electric fields. Process efficiency is treated in conjunction with the quality of sensitive products, such as foods, for a variety of hybrid and combined drying processes. Available in print as 5 Volume Set or as individual volumes. Buy the Set a

Drying is by far the most useful large scale operation method of keeping solid foods safe for long periods of time, and is of fundamental importance in most sectors of food processing. Drying operations need to be precisely controlled and optimized in order to produce a good quality product that has the highest level of nutrient retention and flavor whilst maintaining microbial safety. This volume provides an up to date account of all the major drying technologies employed in the food industry and their underlying scientific principles and effects. Various equipment designs are classified and described. The impact of drying on food properties is covered, and the micro-structural changes caused by the process are examined, highlighting their usefulness in process analysis and food design. Key methods for assessing food properties of dried products are described, and pre-concentration and drying control strategies are reviewed. Thermal hazards and fire/explosion detection and prevention for dryers are discussed in a dedicated chapter. Where appropriate, sample calculations are included for engineers and technologists to follow. The book is directed at food scientists and technologists in industry and research, food engineers and drying equipment manufacturers.

Finite Element Analysis and Computational Fluid Dynamics have been introduced in modelling and simulation of drying and storage systems, these techniques are expected to dominate the future research and development of drying and storages, and should reduce losses and improve the quality of agricultural products, enhancing food security globally. Drying and Storage of Cereal Grains, Second Edition, covers the wide spectrum of drying and storage methods applied to economically important cereal produce, providingnumerical examples for better understanding the complexity in drying and storage systems through modelling and simulation, aiding design and management of drying and storage systems. Chapters 1 to 8 look at air and grain moisture equilibria, psychrometry, physical and thermal properties of cereal grains, principles of air flow, and provide detailed analyses of grain drying.Chapters 9 to 13 focus on temperature and moisture in grain storages, and provide comprehensive treatment of modern grain storage systems. The book also includes a number of unsolved problems at the end of each chapter for further practice. This revised second edition includes new sections on – heat of sorption finite element modeling of single kernel CFD modeling of fluidized bed drying exergy analysis and neural network modeling numerical solution of two dimensional temperature and moisture changes in stored grain This book will provide students in agricultural engineering and food engineering with a wide spectrum of drying and storage studies previously unavailable in a single monograph. It will also serve as an excellent reference for practicing agricultural engineers, food engineers and food technologists.