Medical Statistics from Scratch

The 5th edition of this popular introduction to statistics for the medical and health sciences has undergone a significant revision, with several new chapters added and examples refreshed throughout the book. Yet it retains its central philosophy to explain medical statistics with as little technical detail as possible, making it accessible to a wide audience.  Helpful multi-choice exercises are included at the end of each chapter, with answers provided at the end of the book. Each analysis technique is carefully explained and the mathematics kept to minimum. Written in a style suitable for statisticians and clinicians alike, this edition features many real and original examples, taken from the authors' combined many years' experience of designing and analysing clinical trials and teaching statistics. Students of the health sciences, such as medicine, nursing, dentistry, physiotherapy, occupational therapy, and radiography should find the book useful, with examples relevant to their disciplines. The aim of training courses in medical statistics pertinent to these areas is not to turn the students into medical statisticians but rather to help them interpret the published scientific literature and appreciate how to design studies and analyse data arising from their own projects. However, the reader who is about to design their own study and collect, analyse and report on their own data will benefit from a clearly written book on the subject which provides practical guidance to such issues. The practical guidance provided by this book will be of use to professionals working in and/or managing clinical trials, in academic, public health, government and industry settings, particularly medical statisticians, clinicians, trial co-ordinators. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations.

Medical Statistics provides the necessary statistical tools to enable researchers to undertake and understand evidence-based clinical research. It is a practical guide to conducting statistical research and interpreting statistics in the context of how the participants were recruited, how the study was designed, what types of variables were used, what effect size was found, and what the P values mean. It guides researchers through the process of selecting the correct statistics and show how to best report results for presentation and publication. Clear and concise explanations, combined with plenty of examples and tabulated explanations are based on the authors’ popular medical statistics courses. The table of contents is divided into sections according to whether data are continuous or categorical in nature as this distinction is fundamental to selecting the correct statistics. Each chapter provides a clear step-by-step guide to each statistical test with practical instructions on how to generate and interpret the numbers, and present the results as scientific tables or graphs. The chapters conclude with critical appraisal guidelines to help researchers review the reporting of results from each type of statistical test. This new edition includes a new chapter on repeated measures and mixed models and a helpful glossary of terms provides an easy reference that applies to all chapters.

Holistic approach to understanding medical statistics This hands-on guide is much more than a basic medical statistics introduction. It equips you with the statistical tools required for evidence-based clinical research. Each chapter provides a clear step-by-step guide to each statistical test with practical instructions on how to generate and interpret the numbers, and present the results as scientific tables or graphs. Showing you how to: analyse data with the help of data set examples (Click here to download datasets) select the correct statistics and report results for publication or presentation understand and critically appraise results reported in the literature Each statistical test is linked to the research question and the type of study design used. There are also checklists for critically appraising the literature and web links to useful internet sites. Clear and concise explanations, combined with plenty of examples and tabulated explanations are based on the authors’ popular medical statistics courses. Critical appraisal guidelines at the end of each chapter help the reader evaluate the statistical data in their particular contexts.

Blackwell Publishing is delighted to announce that this book has been Highly Commended in the 2004 BMA Medical Book Competition. Here is the judges' summary of this book: «This is a technical book on a technical subject but presented in a delightful way. There are many books on statistics for doctors but there are few that are excellent and this is certainly one of them. Statistics is not an easy subject to teach or write about. The authors have succeeded in producing a book that is as good as it can get. For the keen student who does not want a book for mathematicians, this is an excellent first book on medical statistics.» Essential Medical Statistics is a classic amongst medical statisticians. An introductory textbook, it presents statistics with a clarity and logic that demystifies the subject, while providing a comprehensive coverage of advanced as well as basic methods. The second edition of Essential Medical Statistics has been comprehensively revised and updated to include modern statistical methods and modern approaches to statistical analysis, while retaining the approachable and non-mathematical style of the first edition. The book now includes full coverage of the most commonly used regression models, multiple linear regression, logistic regression, Poisson regression and Cox regression, as well as a chapter on general issues in regression modelling. In addition, new chapters introduce more advanced topics such as meta-analysis, likelihood, bootstrapping and robust standard errors, and analysis of clustered data. Aimed at students of medical statistics, medical researchers, public health practitioners and practising clinicians using statistics in their daily work, the book is designed as both a teaching and a reference text. The format of the book is clear with highlighted formulae and worked examples, so that all concepts are presented in a simple, practical and easy-to-understand way. The second edition enhances the emphasis on choice of appropriate methods with new chapters on strategies for analysis and measures of association and impact. Essential Medical Statistics is supported by a web site at www.blackwellpublishing.com/essentialmedstats. This useful online resource provides statistical datasets to download, as well as sample chapters and future updates.

Statistical methodology is of great importance to medical research and clinical practice. The Encyclopaedic Companion to Medical Statistics contains readable accounts of the key topics central to current research and practice. Each entry has been written by an individual chosen for both their expertise in the field and their ability to communicate statistical concepts successfully to medical researchers. Real examples from the biomedical literature and relevant illustrations feature in many entries and extensive cross–referencing signposts the reader to related entries. Key Features: Contains accounts of over 400 statistical topics central to current medical research. 80% of first edition entries updated and revised. Presents the latest techniques used at the cutting edge of medical research. Covers common errors in statistical analyses in medicine. Real examples from the biomedical literature and relevant illustrations feature throughout. Contains contributions from over 70 experts in the field. Medical researchers, researchers and practitioners in medical research and statistics will benefit greatly from this book.

Medical Statistics at a Glance is a concise and accessible introduction and revision aid for this complex subject. The self-contained chapters explain the underlying concepts of medical statistics and provide a guide to the most commonly used statistical procedures. This new edition of Medical Statistics at a Glance: Presents key facts accompanied by clear and informative tables and diagrams Focuses on illustrative examples which show statistics in action, with an emphasis on the interpretation of computer data analysis rather than complex hand calculations Includes extensive cross-referencing, a comprehensive glossary of terms and flow-charts to make it easier to choose appropriate tests Now provides the learning objectives for each chapter Includes a new chapter on Developing Prognostic Scores Includes new or expanded material on study management, multi-centre studies, sequential trials, bias and different methods to remove confounding in observational studies, multiple comparisons, ROC curves and checking assumptions in a logistic regression analysis The companion website at www.medstatsaag.com contains supplementary material including an extensive reference list and multiple choice questions (MCQs) with interactive answers for self-assessment. Medical Statistics at a Glance will appeal to all medical students, junior doctors and researchers in biomedical and pharmaceutical disciplines. Reviews of the previous editions «The more familiar I have become with this book, the more I appreciate the clear presentation and unthreatening prose. It is now a valuable companion to my formal statistics course.» –International Journal of Epidemiology «I heartily recommend it, especially to first years, but it's equally appropriate for an intercalated BSc or Postgraduate research. If statistics give you headaches – buy it. If statistics are all you think about – buy it.» –GKT Gazette «…I unreservedly recommend this book to all medical students, especially those that dislike reading reams of text. This is one book that will not sit on your shelf collecting dust once you have graduated and will also function as a reference book.» –4th Year Medical Student, Barts and the London Chronicle, Spring 2003

Statistics is confusing, even for smart, technically competent people. And many students and professionals find that existing books and web resources don’t give them an intuitive understanding of confusing statistical concepts. That is why this book is needed. Some of the unique qualities of this book are: • Easy to Understand: Uses unique “graphics that teach” such as concept flow diagrams, compare-and-contrast tables, and even cartoons to enhance “rememberability.” • Easy to Use: Alphabetically arranged, like a mini-encyclopedia, for easy lookup on the job, while studying, or during an open-book exam. • Wider Scope: Covers Statistics I and Statistics II and Six Sigma Black Belt, adding such topics as control charts and statistical process control, process capability analysis, and design of experiments. As a result, this book will be useful for business professionals and industrial engineers in addition to students and professionals in the social and physical sciences. In addition, each of the 60+ concepts is covered in one or more articles. The 75 articles in the book are usually 5–7 pages long, ensuring that things are presented in “bite-sized chunks.” The first page of each article typically lists five “Keys to Understanding” which tell the reader everything they need to know on one page. This book also contains an article on “Which Statistical Tool to Use to Solve Some Common Problems”, additional “Which to Use When” articles on Control Charts, Distributions, and Charts/Graphs/Plots, as well as articles explaining how different concepts work together (e.g., how Alpha, p, Critical Value, and Test Statistic interrelate). ANDREW A. JAWLIK received his B.S. in Mathematics and his M.S. in Mathematics and Computer Science from the University of Michigan. He held jobs with IBM in marketing, sales, finance, and information technology, as well as a position as Process Executive. In these jobs, he learned how to communicate difficult technical concepts in easy – to – understand terms. He completed Lean Six Sigma Black Belt coursework at the IASSC – accredited Pyzdek Institute. In order to understand the confusing statistics involved, he wrote explanations in his own words and graphics. Using this material, he passed the certification exam with a perfect score. Those statistical explanations then became the starting point for this book.

Statistic: A Concise Mathematical Introduction for Students and Scientists offers a one academic term text that prepares the student to broaden their skills in statistics, probability and inference, prior to selecting their follow-on courses in their chosen fields, whether it be engineering, computer science, programming, data sciences, business or economics.  The book places focus early on continuous measurements, as well as discrete random variables. By invoking simple and intuitive models and geometric probability, discrete and continuous experiments and probabilities are discussed throughout the book in a natural way. Classical probability, random variables, and inference are discussed, as well as material on understanding data and topics of special interest. Topics discussed include: • Classical equally likely outcomes • Variety of models of discrete and continuous probability laws • Likelihood function and ratio • Inference • Bayesian statistics With the growth in the volume of data generated in many disciplines that is enabling the growth in data science, companies now demand statistically literate scientists and this textbook is the answer, suited for undergraduates studying science or engineering, be it computer science, economics, life sciences, environmental, business, amongst many others. Basic knowledge of bivariate calculus, R language, Matematica and JMP is useful, however there is an accompanying website including sample R and Mathematica code to help instructors and students.

Explores mathematical statistics in its entirety—from the fundamentals to modern methods This book introduces readers to point estimation, confidence intervals, and statistical tests. Based on the general theory of linear models, it provides an in-depth overview of the following: analysis of variance (ANOVA) for models with fixed, random, and mixed effects; regression analysis is also first presented for linear models with fixed, random, and mixed effects before being expanded to nonlinear models; statistical multi-decision problems like statistical selection procedures (Bechhofer and Gupta) and sequential tests; and design of experiments from a mathematical-statistical point of view. Most analysis methods have been supplemented by formulae for minimal sample sizes. The chapters also contain exercises with hints for solutions. Translated from the successful German text, Mathematical Statistics requires knowledge of probability theory (combinatorics, probability distributions, functions and sequences of random variables), which is typically taught in the earlier semesters of scientific and mathematical study courses. It teaches readers all about statistical analysis and covers the design of experiments. The book also describes optimal allocation in the chapters on regression analysis. Additionally, it features a chapter devoted solely to experimental designs. Classroom-tested with exercises included Practice-oriented (taken from day-to-day statistical work of the authors) Includes further studies including design of experiments and sample sizing Presents and uses IBM SPSS Statistics 24 for practical calculations of data Mathematical Statistics is a recommended text for advanced students and practitioners of math, probability, and statistics.