Micro, Nanosystems and Systems on Chips

Emphasizing their emerging capabilities, this volume provides a strong foundation for an understanding of how micro- and nanotechnologies used in biomedical research have evolved from concepts to working platforms. Volume editor Christopher Love has assembled here a highly interdisciplinary group of authors with backgrounds ranging from chemical engineering right up to materials science to reflect how the intersection of ideas from biology with engineering disciplines has spurred on innovations. In fact, a number of the basic technologies described are reaching the market to advance the discovery and development of biopharmaceuticals. The first part of the book focuses on microsystems for single-cell analysis, examining tools and techniques used to isolate cells from a range of biological samples, while the second part is dedicated to tiny technologies for modulating biological systems at the scale of individual cells, tissues or whole organisms. New tools are described which have a great potential for (pre)clinical development of interventions in a range of illnesses, such as cancer and neurological diseases. Besides describing the promising applications, the authors also highlight the ongoing challenges and opportunities in the field.

Providing a detailed overview of the fundamentals and latest developments in the field of energy autonomous microsystems, this book delivers an in-depth study of the applications in the fields of health and usage monitoring in aeronautics, medical implants, and home automation, drawing out the main specifications on such systems. Introductory information on photovoltaic, thermal and mechanical energy harvesting, and conversion, is given, along with the latest results in these fields. This book also provides a state of the art of ultra-low power sensor interfaces, digital signal processing and wireless communications. In addition, energy optimizations at the sensor node and sensors network levels are discussed, thus completing this overview. This book details the challenges and latest techniques available to readers who are interested in this field. A major strength of this book is that the first three chapters are application orientated and thus, by setting the landscape, introduce the technical chapters. There is also a good balance between the technical application, covering all the system-related aspects and, within each chapter, details on the physics, materials and technologies associated with electronics. Contents Introduction. Introduction to Energy Autonomous Micro
and Nano Systems and Presentation of Contributions, Marc Belleville and Cyril Condemine. 1. Sensors at the Core of Building Control, Gilles Chabanis, Laurent Chiesi, Hynek Raisigel,
Isabelle Ressejac and V?ronique Boutin. 2. Toward Energy Autonomous MedicalImplants, Raymond Campagnolo and Daniel Kroiss. 3. Energy Autonomous Systems in Aeronautic Applications, Thomas Becker, Jirka Klaue and Martin Kluge. 4. Energy Harvesting by Photovoltaic Effect, Emmanuelle Rouvi?re, Simon Perraud, Cyril Condemine and
Guy Waltisperger. 5. Mechanical Energy Harvesting, Ghislain Despesse, Jean Jacques Chaillout,
S?bastien Boisseau and Claire Jean-Mistral. 6. Thermal Energy Harvesting, Tristan Caroff, Emmanuelle Rouvi?re and J?r?me Willemin. 7. Lithium Micro-Batteries, Rapha?l Salot. 8. Ultra-Low-Power Sensors, Pascal Nouet, Norbert Dumas, Laurent Latorre and
Fr?d?rick Mailly. 9. Ultra-Low-Power Signal Processing in Autonomous Systems, Christian Piguet. 10. Ultra-Low-Power Radio Frequency Communications and Protocols, Eric Mercier. 11. Energy Management in an Autonomous Microsystem, Jean-Fr?d?ric Christmann, Edith Beigne, Cyril Condemine, J?r?me Willemin and Christian Piguet. 12. Optimizing Energy Efficiency of Sensor Networks, Olivier Sentieys and Olivier Berder.

A discussion of the fundamental changes that occur when dynamical systems from the fields of nonlinear optics, solids, hydrodynamics and biophysics are scaled down to nanosize. The authors are leading scientists in the field and each of their contributions provides a broader introduction to the specific area of research. In so doing, they include both the experimental and theoretical point of view, focusing especially on the effects on the nonlinear dynamical behavior of scaling, stochasticity and quantum mechanics. For everybody working on the synthesis and integration of nanoscopic devices who sooner or later will have to learn how to deal with nonlinear effects.

New micro and nanopatterning technologies have been developed in the last years as less costly and more flexible alternatives to phtolithograpic processing. These technologies have not only impacted on recent developments in microelectronics, but also in emerging fields such as disposable biosensors, scaffolds for tissue engineering, non-biofouling coatings, high adherence devices, or photonic structures for the visible spectrum. This handbook presents the current processing methods suitable for the fabrication of micro- and nanostructured surfaces made out of polymeric materials. It covers the steps and materials involved, the resulting structures, and is rounded off by a part on applications. As a result, chemists, material scientists, and physicists gain a critical understanding of this topic at an early stage of its development.

Change and motion define and constantly reshape the world around us, on scales from the molecular to the global. In particular, the subtle interplay between chemical reactions and molecular transport gives rise to an astounding richness of natural phenomena, and often manifests itself in the emergence of intricate spatial or temporal patterns. The underlying theme of this book is that by “setting chemistry in motion” in a proper way, it is not only possible to discover a variety of new phenomena, in which chemical reactions are coupled with diffusion, but also to build micro-/nanoarchitectures and systems of practical importance. Although reaction and diffusion (RD) processes are essential for the functioning of biological systems, there have been only a few examples of their application in modern micro- and nanotechnology. Part of the problem has been that RD phenomena are hard to bring under experimental control, especially when the system’s dimensions are small. Ultimately this book will guide the reader through all the aspects of these systems – from understanding the basics to practical hints and then to applications and interpretation of results. Topics covered include: An overview and outlook of both biological and man-made reaction-diffusion systems. The fundamentals and mathematics of diffusion and chemical reactions. Reaction-diffusion equations and the methods of solving them. Spatial control of reaction-diffusion at small scales. Micro- and nanofabrication by reaction-diffusion. Chemical clocks and periodic precipitation structures. Reaction-diffusion in soft materials and at solid interfaces. Microstructuring of solids using RD. Reaction-diffusion for chemical amplification and sensing. RD in three dimensions and at the nanoscale, including nanosynthesis. This book is aimed at all those who are interested in chemical processes at small scales, especially physical chemists, chemical engineers, and material scientists. The book can also be used for one-semester, graduate elective courses in chemical engineering, materials science, or chemistry classes.

Colloidal processing has always been a major processing method. It facilitates control of particle interactions through a wide variety of schemes, which include surface coating, dispersion additives, and solvent control, among others. Controlling particle interactions also permits better resultant rheology and controlled green microstructures via a wide range of forming methods. In recent years, the particle size involved has been broadened into both the nanometer and the larger than micrometer ranges. This book covers fundamental issues encountered in colloidal processing nano-(less than 0.1 micron), micro-(from 0.1 to 5 micron) and macro-(larger than 5 micron) particulate systems and at the same time explore applications for these developments. Proceedings of the symposium held at the 105th Annual Meeting of The American Ceramic Society, April 27-30, in Nashville, Tennessee; Ceramic Transactions, Volume 152.

Bringing together experts from the various disciplines involved, this first comprehensive overview of the current level of stress engineering on the nanoscale is unique in combining the theoretical fundamentals with simulation methods, model systems and characterization techniques. Essential reading for researchers in microelectronics, optoelectronics, sensing, and photonics.

Systems engineering is the design of a complex interconnection of many elements (a system) to maximize a specific measure of system performance. It consists of two parts: modeling, in which each element of the system and its performance criteria are described; and optimization in which adjustable elements are tailored to allow peak performance. Systems engineering is applied to vast numbers of problems in industry and the military. An example of systems engineering at work is the control of the timing of thousands of city traffic lights to maximize traffic flow. The complex and intricate field of electronics and computers is perfectly suited for systems engineering analysis and in turn, advances in communications and computer technology have made more advanced systems engineering problems solvable. Thus, the two areas fed off of one another. This book is a basic introduction to the use of models and methods in the engineering design of systems. It is aimed at students as well as practicing engineers. The concept of the «systems of systems» is discussed extensively, after a critical comparison of the different definitions and a range of various practical illustrations. It also provides key answers as to what a system of systems is and how its complexity can be mastered.

The book gathers the major issues involved in the practical design of Power Management solutions in wireless products as Internet-of-things. Presentation is not about state-of-the-art but about appropriation of validated recent technologies by practicing engineers. The book delivers insights on major trade-offs and a presentation of examples as a cookbook. The content is segmented in chapters to make access easier for the lay-person.

A comprehensive guide to the theory, methodology, and development for modeling systems of systems Modeling and Managing Interdependent Complex Systems of Systems examines the complexity of, and the risk to, emergent interconnected and interdependent complex systems of systems in the natural and the constructed environment, and in its critical infrastructures. For systems modelers, this book focuses on what constitutes complexity and how to understand, model and manage it.Previous modeling methods for complex systems of systems were aimed at developing theory and methodologies for uncoupling the interdependencies and interconnections that characterize them. In this book, the author extends the above by utilizing public- and private- sector case studies; identifies, explores, and exploits the core of interdependencies; and seeks to understand their essence via the states of the system, and their dominant contributions to the complexity of systems of systems. The book proposes a reevaluation of fundamental and practical systems engineering and risk analysis concepts on complex systems of systems developed over the past 40 years. This important resource: Updates and streamlines systems engineering theory, methodology, and practice as applied to complex systems of systems Introduces modeling methodology inspired by philosophical and conceptual thinking from the arts and sciences Models the complexity of emergent interdependent and interconnected complex systems of systems by analyzing their shared states, decisions, resources, and decisionmakers Written for systems engineers, industrial engineers, managers, planners, academics and other professionals in engineering systems and the environment,this text is the resource for understanding the fundamental principles of modeling and managing complex systems of systems, and the risk thereto.