Numerical Solution of Partial Differential Equations in Science and Engineering

This book offers a predominantly theoretical coverage of statistical prediction, with some potential applications discussed, when data and/ or parameters belong to a large or infinite dimensional space. It develops the theory of statistical prediction, non-parametric estimation by adaptive projection – with applications to tests of fit and prediction, and theory of linear processes in function spaces with applications to prediction of continuous time processes. This work is in the Wiley-Dunod Series co-published between Dunod (www.dunod.com) and John Wiley and Sons, Ltd.

Fundamental concepts of mathematical modeling Modeling is one of the most effective, commonly used tools in engineering and the applied sciences. In this book, the authors deal with mathematical programming models both linear and nonlinear and across a wide range of practical applications. Whereas other books concentrate on standard methods of analysis, the authors focus on the power of modeling methods for solving practical problems-clearly showing the connection between physical and mathematical realities-while also describing and exploring the main concepts and tools at work. This highly computational coverage includes: * Discussion and implementation of the GAMS programming system * Unique coverage of compatibility * Illustrative examples that showcase the connection between model and reality * Practical problems covering a wide range of scientific disciplines, as well as hundreds of examples and end-of-chapter exercises * Real-world applications to probability and statistics, electrical engineering, transportation systems, and more Building and Solving Mathematical Programming Models in Engineering and Science is practically suited for use as a professional reference for mathematicians, engineers, and applied or industrial scientists, while also tutorial and illustrative enough for advanced students in mathematics or engineering.

Over the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials. * The various approaches are presented within a general unified framework. * Meta-analysis techniques are described in detail, from their theoretical development through to practical implementation. * Each topic discussed is supported by detailed worked examples. * A comparison of fixed and random effects approaches is included, as well as a discussion of Bayesian methods and cumulative meta-analysis. * Fully documented programs using standard statistical procedures in SAS are available on the Web. Ideally suited for practising statisticians and statistically-minded medical professionals, the book will also be of use to graduate students of medical statistics. The book is a self-contained and comprehensive account of the subject and an essential purchase for anyone involved in clinical trials.

The field of high-throughput genetic experimentation is evolving rapidly, with the advent of new technologies and new venues for data mining. Bayesian methods play a role central to the future of data and knowledge integration in the field of Bioinformatics. This book is devoted exclusively to Bayesian methods of analysis for applications to high-throughput gene expression data, exploring the relevant methods that are changing Bioinformatics. Case studies, illustrating Bayesian analyses of public gene expression data, provide the backdrop for students to develop analytical skills, while the more experienced readers will find the review of advanced methods challenging and attainable. This book: Introduces the fundamentals in Bayesian methods of analysis for applications to high-throughput gene expression data. Provides an extensive review of Bayesian analysis and advanced topics for Bioinformatics, including examples that extensively detail the necessary applications. Accompanied by website featuring datasets, exercises and solutions. Bayesian Analysis of Gene Expression Data offers a unique introduction to both Bayesian analysis and gene expression, aimed at graduate students in Statistics, Biomedical Engineers, Computer Scientists, Biostatisticians, Statistical Geneticists, Computational Biologists, applied Mathematicians and Medical consultants working in genomics. Bioinformatics researchers from many fields will find much value in this book.

An innovative treatment of mathematical methods for a multidisciplinary audience Clearly and elegantly presented, Mathematical Methods in Science and Engineering provides a coherent treatment of mathematical methods, bringing advanced mathematical tools to a multidisciplinary audience. The growing interest in interdisciplinary studies has brought scientists from many disciplines such as physics, mathematics, chemistry, biology, economics, and finance together, which has increased the demand for courses in upper-level mathematical techniques. This book succeeds in not only being tuned in to the existing practical needs of this multidisciplinary audience, but also plays a role in the development of new interdisciplinary science by introducing new techniques to students and researchers. Mathematical Methods in Science and Engineering's modular structure affords instructors enough flexibility to use this book for several different advanced undergraduate and graduate level courses. Each chapter serves as a review of its subject and can be read independently, thus it also serves as a valuable reference and refresher for scientists and beginning researchers. There are a growing number of research areas in applied sciences, such as earthquakes, rupture, financial markets, and crashes, that employ the techniques of fractional calculus and path integrals. The book's two unique chapters on these subjects, written in a style that makes these advanced techniques accessible to a multidisciplinary audience, are an indispensable tool for researchers and instructors who want to add something new to their compulsory courses. Mathematical Methods in Science and Engineering includes: * Comprehensive chapters on coordinates and tensors and on continuous groups and their representations * An emphasis on physical motivation and the multidisciplinary nature of the methods discussed * A coherent treatment of carefully selected topics in a style that makes advanced mathematical tools accessible to a multidisciplinary audience * Exercises at the end of every chapter and plentiful examples throughout the book Mathematical Methods in Science and Engineering is not only appropriate as a text for advanced undergraduate and graduate physics programs, but is also appropriate for engineering science and mechanical engineering departments due to its unique chapter coverage and easily accessible style. Readers are expected to be familiar with topics typically covered in the first three years of science and engineering undergraduate programs. Thoroughly class-tested, this book has been used in classes by more than 1,000 students over the past eighteen years.