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Optics in Instruments. Applications in Biology and Medicine

Optics is a science which covers a very large domain and is experiencing indisputable growth. It has enabled the development of a considerable number of instruments, the optical component or methodology of which is often the essential part of portent systems. This book sets out show how optical physical phenomena such as lasers – the basis of instruments of measurement – are involved in the fields of biology and medicine. Optics in Instruments: Applications in Biology and Medicine details instruments and measurement systems using optical methods in the visible and near-infrared, as well as their applications in biology and medicine, through looking at confocal laser scanning microscopy, the basis of instruments performing in biological and medical analysis today, and flow cytometry, an instrument which measures at high speed the parameters of a cell passing in front of one or more laser beams. The authors also discuss optical coherence tomography (OCT), which is an optical imaging technique using non-contact infrared light, the therapeutic applications of lasers, where they are used for analysis and care, and the major contributions of plasmon propagation in the field of life sciences through instrumental developments, focusing on propagating surface plasmons (PSP) and localized plasmons (LP). Contents: 1. Confocal Laser Scanning Microscopy, Thomas Olivier and Baptiste Moine. 2. Flow Cytometry (FCM) Measurement of Cells in Suspension, Odile Sabido. 3. Optical Coherence Tomography, Claude Boccara and Arnaud Dubois. 4. Therapeutic Applications of Lasers, Genevi?ve Bourg-Heckly and Serge Mordon. 5. Plasmonics, Emmanuel Fort. About the Authors Jean-Pierre Goure is Emeritus Professor of optics at Jean Monnet University in Saint-Etienne, France, and was previously director of the UMR 5516 laboratory linked with CNRS. He is the author of more than 100 publications in various fields, such as spectroscopy, instrumentation, sensors, optical fiber and optical communications. He was also previously deputy director in engineering science at CNRS and a member of several scientific associations such as the French Optical Society and the European Optical Society.

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Aluminium in Biology and Medicine

Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain. Examines the chemistry and biology of aluminum compounds focusing on the evidence for and against aluminum's role in Alzheimer's disease.

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Protein Moonlighting in Biology and Medicine

The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.

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Gas Chromatography in Biology and Medicine

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

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Growth Factors in Biology and Medicine

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Genomics and Proteomics Engineering in Medicine and Biology

Current applications and recent advances in genomics and proteomics Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding. Topics discussed include: Qualitative knowledge models Interpreting micro-array data Gene regulation bioinformatics Methods to analyze micro-array Cancer behavior and radiation therapy Error-control codes and the genome Complex life science multi-database queries Computational protein analysis Tumor and tumor suppressor proteins interactions

Цена 15040 руб.

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Redox Signaling and Regulation in Biology and Medicine

This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.

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Chemical Biology in Regenerative Medicine

Chemical Biology in Regenerative Medicine: Bridging Stem Cells and Future Therapies The field of regenerative medicine has advanced at a rapid pace and this comprehensive summary of new developments is a timely contribution to the field as clinical trials have begun to assess the safety and efficacy of cell-based therapies. In Chemical Biology in Regenerative Medicine, an international team of experts provides an overview of progress towards clinical application in the areas of transplantation (allogenic and autologous), manipulation of niche environment and homing, and cell reprogramming (trans-differentiation and de-differentiation). The book highlights the interdisciplinary approaches undertaken to resolve current technical problems in regenerative medicine, with special attention paid to small molecules and biomaterials engineering. This volume provides an essential overview of this emerging technology for researchers in academic, industrial and clinical environments working in regenerative medicine, chemical biology, biochemistry, cell biology, biomaterials and bioengineering. It is appropriate for training students and newcomers to the field, benefitting readers in broadening their knowledge and giving them insights to regenerative chemical biology, as well as encouraging readers to implement the key points in their own fields of study to develop new technologies.

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Algorithms in Computational Molecular Biology. Techniques, Approaches and Applications

This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles have failed, in offering a wide range of information from the introductory fundamentals right up to the latest, most advanced levels of study.

Цена 17660 руб.

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Multiscale Modeling of Particle Interactions. Applications in Biology and Nanotechnology

Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.

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Encyclopedia of Glass Science, Technology, History, and Culture

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Survey Measurement and Process Quality

An in-depth look at current issues, new research findings, and interdisciplinary exchange in survey methodology and processing Survey Measurement and Process Quality extends the marriage of traditional survey issues and continuous quality improvement further than any other contemporary volume. It documents the current state of the field, reports new research findings, and promotes interdisciplinary exchange in questionnaire design, data collection, data processing, quality assessment, and effects of errors on estimation and analysis. The book's five sections discuss a broad range of issues and topics in each of five major areas, including * Questionnaire design–conceptualization, design of rating scales for effective measurement, self-administered questionnaires, and more * Data collection–new technology, interviewer effects, interview mode, children as respondents * Post-survey processing and operations–modeling of classification operations, coding based on such systems, editing, integrating processes * Quality assessment and control–total quality management, developing current best methods, service quality, quality efforts across organizations * Effects of misclassification on estimation, analysis, and interpretation–misclassification and other measurement errors, new variance estimators that account for measurement error, estimators of nonsampling error components in interview surveys Survey Measurement and Process Quality is an indispensable resource for survey practitioners and managers as well as an excellent supplemental text for undergraduate and graduate courses and special seminars.

Цена 19984 руб.

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Sense and Sensitivity

Sense and Sensitivity advances a novel research proposal in the nascent field of formal pragmatics, exploring in detail the semantics and pragmatics of focus in natural language discourse. The authors develop a new account of focus sensitivity, and show that what has hitherto been regarded as a uniform phenomenon in fact results from three different mechanisms. The book Makes a major contribution to ongoing research in the area of focus sensitivity – a field exploring interactions between sound and meaning, specifically the dependency some words have on the effects of focus, such as «she only LIKES me» (i.e. nothing deeper) compared to «she only likes ME» (i.e. nobody else) Discusses the features of the QFC theory (Quasi association, Free association, and Conventional association), a new account of focus implying a tripartite typology of focus-sensitive expressions Presents novel cross-linguistic data on focus and focus sensitivity that will be relevant across a range of linguistic sub-fields: semantics and pragmatics, syntax, and intonational phonology Concludes with a case study of exclusives (like “only”), arguing that the entire existing literature has missed crucial generalizations, and for the first time explaining the focus sensitivity of these expressions in terms of their meaning and discourse function

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The Law of Fundraising

Untangle the web of fundraising regulations, with the latest updates for 2018 The Law of Fundraising is the definitive reference by the field's most respected authority, and the only book to tackle the increasingly complex maze of federal and state fundraising regulations. Updated to cover the latest changes to fundraising law for 2018, this book includes new coverage of donor-advised funds, international fundraising, and the IRS's charitable spending initiative alongside updates on Form 990, political fundraising, and more. Both state and federal regulations are covered with an emphasis on administrative, tax, and constitutional law, alongside expert discussion on compliance issues, trends, and upcoming legislation. Accessible language aids in conceptual understanding, while extensive tables of cases, IRS rulings and pronouncements, checklists, and sample forms facilitate correct application. The companion website features additional tables, appendices, IRS guidelines, and other useful documents, providing attorneys, accountants, and nonprofit professionals with a rich toolkit for ensuring compliance. With all topics pertaining to finance under increasing federal scrutiny, laws surrounding fundraising are becoming increasingly difficult to parse. Mistakes can impact the nonprofit's bottom line, so keeping up-to-date is crucial; this book provides a comprehensive reference to the latest developments, along with expert forecasting of what is to come. Understand the latest state and federal laws surrounding fundraising activities Learn how the law governs Internet fundraising and other emerging issues Get up to date on the new rules surrounding donor-advised funds and international fundraising Examine prospective laws, regulatory trends, and how new rules impact fundraising professionals Fundraising is critical to the nonprofit's ability to carry out their mission, yet the regulatory tangle at both the state and federal level can be a nightmare to navigate. The Law of Fundraising streamlines compliance with the latest legal developments and invaluable tools for application.

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Scientific Integrity and Ethics in the Geosciences

Science is built on trust. The assumption is that scientists will conduct their work with integrity, honesty, and a strict adherence to scientific protocols. Written by geoscientists for geoscientists, Scientific Integrity and Ethics in the Geosciences acquaints readers with the fundamental principles of scientific ethics and shows how they apply to everyday work in the classroom, laboratory, and field. Resources are provided throughout to help discuss and implement principles of scientific integrity and ethics. Volume highlights include: Examples of international and national codes and policies Exploration of the role of professional societies in scientific integrity and ethics References to scientific integrity and ethics in publications and research data Discussion of science integrity, ethics, and geoethics in education Extensive coverage of data applications Scientific Integrity and Ethics in the Geosciences is a valuable resource for students, faculty, instructors, and scientists in the geosciences and beyond. It is also useful for geoscientists working in industry, government, and policymaking. Read an interview with the editors to find out more: https://eos.org/editors-vox/ethics-crucial-for-the-future-of-the-geosciences

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Optics in Instruments. Applications in Biology and Medicine

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