Platelet Proteomics. Principles, Analysis, and Applications

Proteomics provides an introductory insight on proteomics, discussing the basic principles of the field, how to apply specific technologies and instrumentation, and example applications in human health and diseases. With helpful study questions, this textbook presents an easy to grasp and solid overview and understanding of the principles, guidelines, and especially the complex instrumentation operations in proteomics for new students and research scientists. Written by a leader in proteomics studies, Proteomics offers an expert perspective on the field and the future of proteomics.

Basin Analysis is an up-to-date overview of the essential processes of the formation and evolution of sedimentary basins, and their implications for the development of hydrocarbon resources. The new edition features: A consideration of the fundamental physical state of the lithosphere. A discussion on the major types of lithospheric deformation relevant to basin development – stretching and flexure. A new chapter on the effects of mantle dynamics. Radically revised chapters on the basin-fill. A new chapter on the erosional engine for sediment delivery to basins, reflecting the massive and exciting advances in this area in the last decade. Expansion of the techniques used in approaching problems in basin analysis. Updated chapters on subsidence analysis and measurements of thermal maturity of organic and non-organic components of the basin-fill. New material on thermochronological and exposure dating tools. Inclusion of the important petroleum system concept in the updated section on the application to the petroleum play. Visit: www.blackwellpublishing.com/allen for practical exercises related to problems in Basin Analysis 2e. To run the programs you will need a copy of Matlab 6 or 7. An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at HigherEducation@wiley.com for more information.

This book focuses heavily on the principles, analysis and applications of code-division multiple-access (CDMA) techniques in optical communication systems and networks. In this book, the authors intimately discuss modern optical networks and their applications in current and emerging communication technologies, evaluating the quality, speed and number of supported services. In particular, principles and fundamentals of optical CDMA techniques from beginner to advanced levels are heavily covered. Furthermore, the authors concentrate on methods and techniques of various encoding and decoding schemes and their structures, as well as analysis of optical CDMA systems with various transceiver models including advanced multi-level incoherent and coherent modulations with the architecture of access/aggregation networks in mind. Moreover, authors examine intriguing topics of optical CDMA networking, compatibility with IP networks, and implementation of optical multi-rate multi-service CDMA networks. Key features: Expanded coverage of optical CDMA networks, starts from principles and fundamentals Comprehensive mathematical modelling and analysis from signal to system levels Addresses the applications of modern optical networking in the current and emerging communication technologies Greater focus on advanced optical multi-level incoherent and coherent modulations, spreading codes, and transceiver designs Detailed hardware specifications, system-level block diagrams, and network nodes’ functionalities This book appeals to researchers, practicing engineers, and advanced students. It is a practical resource for readers with an interest in optical communications and networks.

An authoritative text that presents the current problems, theories, and applications of mathematical analysis research Mathematical Analysis and Applications: Selected Topics offers the theories, methods, and applications of a variety of targeted topics including: operator theory, approximation theory, fixed point theory, stability theory, minimization problems, many-body wave scattering problems, Basel problem, Corona problem, inequalities, generalized normed spaces, variations of functions and sequences, analytic generalizations of the Catalan, Fuss, and Fuss–Catalan Numbers, asymptotically developable functions, convex functions, Gaussian processes, image analysis, and spectral analysis and spectral synthesis. The authors—a noted team of international researchers in the field— highlight the basic developments for each topic presented and explore the most recent advances made in their area of study. The text is presented in such a way that enables the reader to follow subsequent studies in a burgeoning field of research. This important text: Presents a wide-range of important topics having current research importance and interdisciplinary applications such as game theory, image processing, creation of materials with a desired refraction coefficient, etc. Contains chapters written by a group of esteemed researchers in mathematical analysis Includes problems and research questions in order to enhance understanding of the information provided Offers references that help readers advance to further study Written for researchers, graduate students, educators, and practitioners with an interest in mathematical analysis, Mathematical Analysis and Applications: Selected Topics includes the most recent research from a range of mathematical fields. Michael Ruzhansky, Ph.D., is Professor in the Department of Mathematics at Imperial College London, UK. Dr. Ruzhansky was awarded the Ferran Sunyer I Balaguer Prize in 2014. Hemen Dutta, Ph.D., is Senior Assistant Professor of Mathematics at Gauhati University, India. Ravi P. Agarwal, Ph.D., is Professor and Chair of the Department of Mathematics at Texas A&M University-Kingsville, Kingsville, USA.

Survival analysis concerns sequential occurrences of events governed by probabilistic laws. Recent decades have witnessed many applications of survival analysis in various disciplines. This book introduces both classic survival models and theories along with newly developed techniques. Readers will learn how to perform analysis of survival data by following numerous empirical illustrations in SAS. Survival Analysis: Models and Applications: Presents basic techniques before leading onto some of the most advanced topics in survival analysis. Assumes only a minimal knowledge of SAS whilst enabling more experienced users to learn new techniques of data input and manipulation. Provides numerous examples of SAS code to illustrate each of the methods, along with step-by-step instructions to perform each technique. Highlights the strengths and limitations of each technique covered. Covering a wide scope of survival techniques and methods, from the introductory to the advanced, this book can be used as a useful reference book for planners, researchers, and professors who are working in settings involving various lifetime events. Scientists interested in survival analysis should find it a useful guidebook for the incorporation of survival data and methods into their projects.

Survival analysis concerns sequential occurrences of events governed by probabilistic laws. Recent decades have witnessed many applications of survival analysis in various disciplines. This book introduces both classic survival models and theories along with newly developed techniques. Readers will learn how to perform analysis of survival data by following numerous empirical illustrations in SAS. Survival Analysis: Models and Applications: Presents basic techniques before leading onto some of the most advanced topics in survival analysis. Assumes only a minimal knowledge of SAS whilst enabling more experienced users to learn new techniques of data input and manipulation. Provides numerous examples of SAS code to illustrate each of the methods, along with step-by-step instructions to perform each technique. Highlights the strengths and limitations of each technique covered. Covering a wide scope of survival techniques and methods, from the introductory to the advanced, this book can be used as a useful reference book for planners, researchers, and professors who are working in settings involving various lifetime events. Scientists interested in survival analysis should find it a useful guidebook for the incorporation of survival data and methods into their projects.

A thorough, accessible, and general overview of chemosensors Providing a comprehensive overview of chemosensors—organic molecules designed to bind and sense small molecules or metal ions—and their applications, Chemosensors: Principles, Strategies, and Applications is an accessible one-stop resource for analysts, clinicians, and graduate students studying advanced chemistry and chemosensing. Chemosensors function on a molecular level, generating a signal upon binding. The book reviews their synthesis, design, and applications for detecting biological and organic molecules as well as metal ions. The text highlights applications in drug discovery and catalyses that have not been well covered elsewhere. Covering such topics as molecular recognition, detection methods, design strategies, and important biological issues, the book is broken into four sections that examine intermolecular interactions, strategies in sensor design, detection methods, and case studies in metal, saccharide, and amino acid sensing. An indispensable source of information for chemical and biomedical experts using sensors, Chemosensors includes case studies to make the material both accessible and understandable to chemists of all backgrounds.

This book presents and describes imaging technologies that can be used to study chemical processes and structural interactions in dynamic systems, principally in biomedical systems. The imaging technologies, largely biomedical imaging technologies such as MRT, Fluorescence mapping, raman mapping, nanoESCA, and CARS microscopy, have been selected according to their application range and to the chemical information content of their data. These technologies allow for the analysis and evaluation of delicate biological samples, which must not be disturbed during the profess. Ultimately, this may mean fewer animal lab tests and clinical trials.

An essential guide on high dimensional multivariate time series including all the latest topics from one of the leading experts in the field Following the highly successful and much lauded book, Time Series Analysis—Univariate and Multivariate Methods, this new work by William W.S. Wei focuses on high dimensional multivariate time series, and is illustrated with numerous high dimensional empirical time series. Beginning with the fundamentalconcepts and issues of multivariate time series analysis,this book covers many topics that are not found in general multivariate time series books. Some of these are repeated measurements, space-time series modelling, and dimension reduction. The book also looks at vector time series models, multivariate time series regression models, and principle component analysis of multivariate time series. Additionally, it provides readers with information on factor analysis of multivariate time series, multivariate GARCH models, and multivariate spectral analysis of time series. With the development of computers and the internet, we have increased potential for data exploration. In the next few years, dimension will become a more serious problem. Multivariate Time Series Analysis and its Applications provides some initial solutions, which may encourage the development of related software needed for the high dimensional multivariate time series analysis. Written by bestselling author and leading expert in the field Covers topics not yet explored in current multivariate books Features classroom tested material Written specifically for time series courses Multivariate Time Series Analysis and its Applications is designed for an advanced time series analysis course. It is a must-have for anyone studying time series analysis and is also relevant for students in economics, biostatistics, and engineering.

It is difficult to imagine that the statistical analysis of compositional data has been a major issue of concern for more than 100 years. It is even more difficult to realize that so many statisticians and users of statistics are unaware of the particular problems affecting compositional data, as well as their solutions. The issue of ``spurious correlation'', as the situation was phrased by Karl Pearson back in 1897, affects all data that measures parts of some whole, such as percentages, proportions, ppm and ppb. Such measurements are present in all fields of science, ranging from geology, biology, environmental sciences, forensic sciences, medicine and hydrology. This book presents the history and development of compositional data analysis along with Aitchison's log-ratio approach. Compositional Data Analysis describes the state of the art both in theoretical fields as well as applications in the different fields of science. Key Features: Reflects the state-of-the-art in compositional data analysis. Gives an overview of the historical development of compositional data analysis, as well as basic concepts and procedures. Looks at advances in algebra and calculus on the simplex. Presents applications in different fields of science, including, genomics, ecology, biology, geochemistry, planetology, chemistry and economics. Explores connections to correspondence analysis and the Dirichlet distribution. Presents a summary of three available software packages for compositional data analysis. Supported by an accompanying website featuring R code. Applied scientists working on compositional data analysis in any field of science, both in academia and professionals will benefit from this book, along with graduate students in any field of science working with compositional data.