Population Genetics and Microevolutionary Theory

Now updated for its second edition,  Population Genetics  is the classic, accessible introduction to the concepts of population genetics. Combining traditional conceptual approaches with classical hypotheses and debates, the book equips students to understand a wide array of empirical studies that are based on the first principles of population genetics.  Featuring a highly accessible introduction to coalescent theory, as well as covering the major conceptual advances in population genetics of the last two decades, the second edition now also includes end of chapter problem sets and revised coverage of recombination in the coalescent model, metapopulation extinction and recolonization, and the fixation index.

This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators. The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics. Forward-Time Population Genetics Simulations includes: An overview of currently available forward-time simulation methods, their advantages, and shortcomings An overview and evaluation of currently available software A simuPOP tutorial Applications in population genetics Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.

The goldfish, Carassius auratus, a member of the Carp family, Cyprinidae, has been domesticated for many hundreds of years, as a food fish, a laboratory animal and now most important commercially, for ornamental and aesthetic purposes. There are now many scores of recognised varieties, which have been produced over time by selection processes and other methods described in detail in this stimulating book. Goldfish Varieties and Genetics covers all major aspects relating to goldfish breeding and genetics in a readable and user-friendly style. An account is presented of the domestication and evolution of the goldfish, including comprehensive details of the relevant genetic and biological principles involved in the development strategies and production of new varieties. The book also covers the subject of goldfish appreciation and the international significance of goldfish shows and show standards. The book concludes with an exciting forward look at the potential evolutionary future for the goldfish. This important and timely book brings together, for the first time, a wealth of scientific information, presented in a clear and understandable manner by Dr Joseph Smartt, who has many years' experience working in fish genetics and breeding. The book is a must-have purchase for all serious goldfish breeders, hobbyists and dealers, fish biologists and geneticists, aquarium keepers and aquaculture personnel. The author, Joseph Smartt is a Senior Visiting Research Fellow at the Department of Biological Sciences, University of Southampton, UK.

Animal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits. Molecular and Quantitative Animal Genetics is a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. Molecular and Quantitative Animal Genetics will be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals. Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.

Following the extremely well-received structure of the first edition, this carefully revised and updated new edition now includes much new information of vital importance to those working and researching in the fisheries and aquaculture industries. Commencing with chapters covering genetic variation and how it can be measured, the authors then look at genetic structure in natural populations, followed by a new chapter covering genetics in relation to population size and conservation issues. Genetic variation of traits and triploids and the manipulation of ploidy are fully covered, and another new chapter is included, entitled 'From Genetics to Genomics'. The book concludes with a chapter covering the impact of genetic engineering in aquaculture. With the inclusion of a wealth of up-to-date information, new text and figures and the inclusion of a third author, Pierre Boudry, the second edition of Biotechnology and Genetics in Fisheries and Aquaculture provides an excellent text and reference of great value and use to upper level students and professionals working across fish biology, aquatic sciences, fisheries, aquaculture, genetics and biotechnology. Libraries in all universities and research establishments where biological sciences, fisheries and aquaculture are studied and taught should have several copies of this excellent new edition on their shelves. Completely updated, revised and expanded new edition Subject area of ever increasing importance Expanded authorship Commercially useful information for fish breeders

The recent development of molecular biology and genetic techniques, in particular those that are increasingly being used in practical situations in fish biology, fisheries and aquaculture, has led to a gap in the understanding by many of the science behind these techniques and their correct implementation for maximum results. The authors of this important book, Andy Beaumont and Kate Hoare, have written a text of great clarity, which carefully explains the science and application of molecular and genetic techniques to fisheries and aquaculture situations and what these new technologies have to offer. Contents include a full explanation of genetic variation and its measurement, genetic structure in natural populations, genetics and artificial selection in the hatchery, ploidy manipulation and the use of genetic engineering in aquaculture. Biotechnology and Genetics in Fisheries and Aquaculture is of great use to biological sciences students, particularly those studying marine, freshwater and aquatic biology, fish biology, fisheries, aquaculture, population biology and genetics. The book is also extremely useful as a reference to personnel such as fish farmers and fisheries scientists and all those working in fisheries and aquaculture management and research. Libraries in all universities and research establishments where biological sciences, fisheries and aquaculture are studied and taught should have copies of this book on their shelves.

Focused on basics and processes, this textbook teaches plant biology and agriculture applications with summary and discussion questions in each chapter. Updates each chapter to reflect advances / changes since the first edition, for example: new biotechnology tools and advances, genomics and systems biology, intellectual property issues on DNA and patents, discussion of synthetic biology tools Features autobiographical essays from eminent scientists, providing insight into plant biotechnology and careers Has a companion website with color images from the book and PowerPoint slides Links with author's own website that contains teaching slides and graphics for professors and students: plantsciences.utk.edu/pbg/

This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.