Principles and Practice of Clinical Virology

Principles and Practice of Clinical Virology is the bible for all working in the field of clinical virology – from the trainee to the expert because there’s always something new to learn! As before, the book provides a detailed account of the diagnosis and treatment of virus infections, with a stronger emphasis on clinical expertise and management. Each chapter deals with a single virus or group or viruses and is written by leading international experts in the field. What’s new in this edition … Showcases the wealth of new knowledge acquired on virus infections and reflects the discovery of newly recognized emerging infections, the improvement or development of new vaccines, and an increasing repertoire of antiviral agents for treatment All chapters have been thoroughly revised and there are a number of new contributors, joining the cadre of internationally-recognized experts Includes a new chapter on vaccinology covering the principles relating to the development and use of vaccines generally, which complements the specific vaccines described in the other chapters The two chapters on nosocomial infections have been enlarged and will be particularly useful for those having to advise on the management of hospital-acquired infections Emphasizes the rapid accumulation of new information in such fields as retroviruses, particularly HIV, SARS, hepatitis C and influenza, including avian influenza

Since the publication of the last edition of Principles and Practice of Clinical Bacteriology, our understanding of bacterial genetics and pathogenicity has been transformed due to the availability of whole genome sequences and new technologies such as proteomics and transcriptomics. The present, completely revised second edition of this greatly valued work has been developed to integrate this new knowledge in a clinically relevant manner. Principles and Practice of Clinical Bacteriology, Second Edition, provides the reader with invaluable information on the parasitology, pathogenesis, epidemiology and treatment strategies for each pathogen while offering a succinct outline of the best current methods for diagnosis of human bacterial diseases. With contributions from an international team of experts in the field, this book is an invaluable reference work for all clinical microbiologists, infectious disease physicians, public health physicians and trainees within these disciplines.

Pathy’s PRINCIPLES AND PRACTICE OF GERIATRIC MEDICINE The latest edition of the gold standard in geriatric medicine references Pathy’s Principles and Practice of Geriatric Medicine, Sixth Edition delivers a comprehensive overview of the subject, offering up-to-date, evidence-based, information about the many, and varied, problems suffered by ageing patients. In this latest edition, the authors take a refreshed approach to the material by rigorously applying the latest scientific research to clinical practice and increasing the use of visual examples, algorithms, and clinical practice points. Thoroughly updated throughout, the chapters give readers a truly global perspective on geriatric medicine that reflect the most recent changes in treatment options and medical conditions. In addition to new chapters on a range of recent and emerging topics, clinical practice points, and visual evidence—including MRI scans—the book also offers a: Thorough introduction to relevant biological, social, and community perspectives on caring for mature and ageing patients, as well as medicine prescribing for older patients Comprehensive exploration of eating disorders that commonly occur in the aged and how to maximize the nutritional health of ageing patients Practical discussions of haematological and cardiovascular disorders and diseases in ageing patients In-depth examination of special issues in elder care, including elder abuse, alcoholism and substance abuse, transportation issues, and end-of-life care Perfect for all clinicians working with mature patients, Pathy’s Principles and Practice of Geriatric Medicine will also continue to earn a place in the libraries of allied healthcare workers with ageing patients and clients.

The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not only is it necessary to detect new adverse drug reactions, but the principles and practice of pharmacovigilance apply to the surveillance of a wide range of medicinal products. Stephens' Detection and Evaluation of Adverse Drug Reactions provides a comprehensive review of all aspects of adverse drug reactions throughout the life cycle of a medicine, from toxicology and clinical trials through to pharmacovigilance, risk management, and legal and regulatory requirements. It also covers the safety of biotherapeutics and vaccines and includes new chapters on pharmacogenetics, proactive risk management, societal considerations, and the safety of drugs used in oncology and herbal medicines. This sixth edition of the classic text on drug safety is an authoritative reference text for all those who work in pharmacovigilance or have an interest in adverse drug reactions, whether in regulatory authorities, pharmaceutical companies, or academia. Praise for previous editions "This book presents a comprehensive and wide-ranging overview of the science of pharmacovigilance. For those entering or already experienced in the pharmaceutical sciences, this is an essential work.” – from a review in E-STREAMS «…a key text in the area of pharmacovigilance…extensively referenced and well-written…a valuable resource…» – from a review in The Pharmaceutical Journal

Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.

In this pathbreaking volume, a multidisciplinary team of international experts puts catheter–based treatment techniques in context by exploring the pathobiology of specific diseases alongside a discussion of imaging tools and functional tests, and a comparison to alternative treatment approaches provided by cardiovascular surgery. This comprehensive overview of interventional cardiology: Explains treatments in depth, including imaging techniques and functional tests Serves as both a theoretical and practical guide to available treatment approaches that can be tailored for individual patients Provides the latest scientific data and new surgical alternatives Presents a practically oriented view of the most important interventional strategies Is written by a strong team of well-published and highly-regarded authors, the people whose breakthroughs in the clinic and the lab have made interventional cardiology the dynamic field it is today Practitioners, fellows, and trainees who want a state-of-the-art guide to interventional cardiology can depend on this carefully crafted guide for authoritative information.

Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: «… very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas.» BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.

Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available. It features brand new chapters on the measurement of cell kinetics, obstetric transfusion practice, cord blood, transfusion alternatives and regenerative medicine. Produced jointly with AABB, the world's leading association in the fields of blood banking and transfusion medicine, it now has two companion CD-ROMs-one containing interactive case studies and one containing PDFs of all 66 chapters.

Edited by four leading members of the new generation of medical and healthcare ethicists working in the UK, respected worldwide for their work in medical ethics, Principles of Health Care Ethics, Second Edition is a standard resource for students, professionals, and academics wishing to understand current and future issues in healthcare ethics. With a distinguished international panel of contributors working at the leading edge of academia, this volume presents a comprehensive guide to the field, with state of the art introductions to the wide range of topics in modern healthcare ethics, from consent to human rights, from utilitarianism to feminism, from the doctor-patient relationship to xenotransplantation. This volume is the Second Edition of the highly successful work edited by Professor Raanan Gillon, Emeritus Professor of Medical Ethics at Imperial College London and former editor of the Journal of Medical Ethics, the leading journal in this field. Developments from the First Edition include: The focus on ‘Four Principles Method’ is relaxed to cover more different methods in health care ethics. More material on new medical technologies is included, the coverage of issues on the doctor/patient relationship is expanded, and material on ethics and public health is brought together into a new section.