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A comprehensive account of protozoan and metozoan diseases in modern clinical practice, with orientation towards clinical management of parasitic infections. In the past, parasitology was considered as an obscure subject of little relevance to the majority of clinicians and microbiologists. Over the last decade, however, much has happened to change this, not least the explosion in foreign travel This textbook is the forth in the Principles and Practice series, providing an expansive and detailed coverage of clinical microbiology. It has a similar appeal to that of Zuckerman's, Principles & Practice of Clinical Virology, with an international authorship and emphasis placed on integrating new knowledge in a clinically relevant manner. . An essential, up-to-date sourcebook on the fundamentals of human parasitology . Provides a global approach with renowned and international authorship . Completes the quartet of Principles and Practice series in Microbiology

Principles and Practice of Clinical Virology is the bible for all working in the field of clinical virology – from the trainee to the expert because there’s always something new to learn! As before, the book provides a detailed account of the diagnosis and treatment of virus infections, with a stronger emphasis on clinical expertise and management. Each chapter deals with a single virus or group or viruses and is written by leading international experts in the field. What’s new in this edition … Showcases the wealth of new knowledge acquired on virus infections and reflects the discovery of newly recognized emerging infections, the improvement or development of new vaccines, and an increasing repertoire of antiviral agents for treatment All chapters have been thoroughly revised and there are a number of new contributors, joining the cadre of internationally-recognized experts Includes a new chapter on vaccinology covering the principles relating to the development and use of vaccines generally, which complements the specific vaccines described in the other chapters The two chapters on nosocomial infections have been enlarged and will be particularly useful for those having to advise on the management of hospital-acquired infections Emphasizes the rapid accumulation of new information in such fields as retroviruses, particularly HIV, SARS, hepatitis C and influenza, including avian influenza

Since the publication of the last edition of Principles and Practice of Clinical Bacteriology, our understanding of bacterial genetics and pathogenicity has been transformed due to the availability of whole genome sequences and new technologies such as proteomics and transcriptomics. The present, completely revised second edition of this greatly valued work has been developed to integrate this new knowledge in a clinically relevant manner. Principles and Practice of Clinical Bacteriology, Second Edition, provides the reader with invaluable information on the parasitology, pathogenesis, epidemiology and treatment strategies for each pathogen while offering a succinct outline of the best current methods for diagnosis of human bacterial diseases. With contributions from an international team of experts in the field, this book is an invaluable reference work for all clinical microbiologists, infectious disease physicians, public health physicians and trainees within these disciplines.

The knowledge and practice of clinical virology continues to expand. This new fifth edition has thirty-six comprehensive chapters, each of which has been extensively revised or rewritten, with the addition of new colour plates. This updated version takes into account knowledge accumulated in molecular biology with its applications for laboratory diagnosis, immunisation and antiviral chemotherapy. Each chapter highlights the clinical features and epidemiological patterns of infection. Similarly, in response to the global concern of the threat posed by new viruses, a new chapter on Emerging Infections is included. There is also new material on Hospital Acquired Infections, including some advice relating to SARS, that will be of benefit to those dealing with the day-to-day management of patients in hospital.

Nitrogen is arguably the most important nutrient required by plants. However, the availability of nitrogen is limited in many soils and although the earth's atmosphere consists of 78.1% nitrogen gas (N2) plants are unable to use this form of nitrogen. To compensate , modern agriculture has been highly reliant on industrial nitrogen fertilizers to achieve maximum crop productivity. However, a great deal of fossil fuel is required for the production and delivery of nitrogen fertilizer. Moreover carbon dioxide (CO2) which is released during fossil fuel combustion contributes to the greenhouse effect and run off of nitrate leads to eutrophication of the waterways. Biological nitrogen fixation is an alternative to nitrogen fertilizer. It is carried out by prokaryotes using an enzyme complex called nitrogenase and results in atmospheric N2 being reduced into a form of nitrogen diazotrophic organisms and plants are able to use (ammonia). It is this process and its major players which will be discussed in this book. Biological Nitrogen Fixation is a comprehensive two volume work bringing together both review and original research articles on key topics in nitrogen fixation. Chapters across both volumes emphasize molecular techniques and advanced biochemical analysis approaches applicable to various aspects of biological nitrogen fixation. Volume 1 explores the chemistry and biochemistry of nitrogenases, nif gene regulation, the taxonomy, evolution, and genomics of nitrogen fixing organisms, as well as their physiology and metabolism. Volume 2 covers the symbiotic interaction of nitrogen fixing organisms with their host plants, including nodulation and symbiotic nitrogen fixation, plant and microbial «omics», cyanobacteria, diazotrophs and non-legumes, field studies and inoculum preparation, as well as nitrogen fixation and cereals. Covering the full breadth of current nitrogen fixation research and expanding it towards future advances in the field, Biological Nitrogen Fixation will be a one-stop reference for microbial ecologists and environmental microbiologists as well as plant and agricultural researchers working on crop sustainability.

Building on the strength of the previous two editions, Bergman's Comprehensive Encyclopedia of Human Anatomic Variation is the third installment of the classic human anatomical reference launched by Dr. Ronald Bergman. With both new and updated entries, and now illustrated in full color, the encyclopedia provides an even more comprehensive reference on human variation for anatomists, anthropologists, physicians, surgeons, medical personnel, and all students of anatomy. Developed by a team of editors with extensive records publishing on both human variation and normal human anatomy, Bergman's Comprehensive Encyclopedia of Human Anatomic Variation is the long awaited update to this classic reference.

Global climate change is one of the most serious and pressing issues facing our planet. Rather than a “silver bullet” or a single study that solves it, the study of global climate change is like a beach, with each contribution a grain of sand, gathered together as a whole to create a big picture, moving the science forward. This new groundbreaking study focuses on the adaptation and tolerance of plants and animal life to the harsh conditions brought on by climate change or global warming. Using the papers collected here, scientists can better understand global climate change, its causes, results, and, ultimately, the future of life on our planet. The first section lays out a methodology and conceptual direction of the work as a whole, covering the modeling, approaches, and the impacts studied throughout the book. The second section focuses on certain hypotheses laid out by the authors regarding how plants and animal life can adapt and survive in extreme environments. The third section compiles a series of ecological experiments and their conclusions, and a final section is dedicated to previous scientific breakthroughs in this field and the scientists who made them. Whether for the scientist in the field, the student, or as a reference, this groundbreaking new work is a must-have. Focusing on a small part of the global climate change “beach,” this “grain of sand” is an extremely important contribution to the scientific literature and a step forward in understanding the problems and potentialities of the issue.

This second edition of Principles and Practice of Travel Medicine has been extensively updated to provide a comprehensive description of travel medicine and is an invaluable reference resource to support the clinical practice of travel medicine. This new edition covers the many recent advances in the field, including the development of new and combined vaccines; malaria prophylaxis; emerging new infections; new hazards resulting from travel to long haul destinations; health tourism; and population movements. The chapter on vaccine-preventable diseases includes new developments in licensed vaccines, as well as continent-based recommendations for their administration. There are chapters on the travel health management of high risk travellers, including the diabetic traveller, the immuno-compromised, those with cardiovascular, renal, neurological, gastrointestinal, malignant and other disorders, psychological and psychiatric illnesses, pregnant women, children and the elderly. With increasing numbers of ever more adventurous travellers, there is discussion of travel medicine within extreme environments, whilst the chapter on space tourism may well be considered the future in travel medicine. Principles and Practice of Travel Medicine is an invaluable resource for health care professionals providing advice and clinical care to the traveller.

The Moss Physcomitrella patens has rapidly become an experimental model of choice for many aspects of molecular, cell and developmental biology in plant sciences. With a recently sequenced genome, which has further fuelled interest and research, Physcomitrella is accruing various new labels, from ‘a green yeast’ to the Drosophila, Caenorhabditis or Zebra fish of plant sciences. A truly international collaboration, this timely volume brings together a selection of chapters each composed by experts in their field. The chapters included cover a broad range: From those using P. patens as a marker against other species for evolutionary or ecological studies To those investigating the unique features of P. patens, e.g. gene targeting To those using moss, either as a comparator for other organisms or because of the ease of study in moss, to investigate standard biological processes This landmark publication is essential reading for anyone studying plant evolutionary biology, genomics, molecular and cell biology and genetics. Libraries in all universities and research establishments, where biological and agricultural sciences are studied and taught, should have copies of this important book on their shelves.

Biofilms are predominant mode of life for microbes under natural conditions. The three-dimensional structure of the biofilm provides enhanced protection from physical, chemical and biological stress conditions to associated microbial communities. These complex and highly structured microbial communities play a vital role in maintaining the health of plants, soils and waters. Biofilm associated with plants may be pathogenic or beneficial based on the nature of their interactions. Pathogenic or undesirable biofilm requires control in many situations, including soil, plants, food and water. Written by leading experts from around the world, Biofilms in Plant and Soil Health provides an up-to-date review on various aspects of microbial biofilms, and suggests future and emerging trends in biofilms in plant and soil health. Issues are addressed in four sub areas: I) The fundamentals and significance of biofilm in plant and soil health, and the concept of mono and mixed biofilms by PGPR and fungal biofilms. II) Biochemical and molecular mechanisms in biofilm studies in plant associated bacteria, and techniques in studying biofilms and their characterization, gene expression and enhanced antimicrobial resistance in biofilms, as well as biotic and biotic factors affecting biofilm in vitro. III) The ecological significance of soil associated biofilms and stress management and bioremediation of contaminated soils and degraded ecosystems. IV) Pathogenic biofilm associated with plant and food and its control measures. This book is recommended for students and researchers working in agricultural and environmental microbiology, biotechnology, soil sciences, soil and plant health and plant protection. Researchers working in the area of quorum sensing, biofilm applications, and understanding microbiome of soil and plants will also find it useful.

Microsporidia: Pathogens of Opportunity provides a systematic overview of the biology of microsporidia. Written by leading experts in the field, the book combines background and basic information on microsporidia with descriptive methods and resources for working with the pathogen. Newly revised and updated for its second edition, Microsporidia will continue to be the standard text reference for these pathogenic protists, and is an indispensable research resource for biologists, physicians and parasitologists. This new edition of this publication provides systematic reviews of the biology of this pathogen by leading experts in the field, and will be combined with descriptions of the methods and resources for working with this pathogen. • Provides a comprehensive summary of literature on microsporidia and microsporidiosis • The long-awaited update to the standard microsporidia reference text The Microsporidia and Microsporidiosis • Written by an international team of authors representing each of the main research groups working on microsporidia • Chapters provide comprehensive overviews of general methodology as well as special techniques related to these organisms

Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems. Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo metabolism, fertilization, cryopreservation, signal transduction pathways, chromatin dynamics, epigenetics, reproductive aging, and inflammation. Chapters on non-human primate models also highlight recent advancements into such issues as human in vitro fertilization (IVF) and assisted reproductive technologies (ART). This book offers animal scientists, reproductive biology scientists, clinicians and practitioners, invaluable insights into a wide range of issues at the forefront of human reproductive health.

Companion to Dental Anthropology presents a collection of original readings addressing all aspects and sub-disciplines of the field of dental anthropology—from its origins and evolution through to the latest scientific research. Represents the most comprehensive coverage of all sub-disciplines of dental anthropology available today Features individual chapters written by experts in their specific area of dental research Includes authors who also present results from their research through case studies or voiced opinions about their work Offers extensive coverage of topics relating to dental evolution, morphometric variation, and pathology

Probably the best-studied stream on earth. The result of unmatched long-term data taken by the Max-Planck outstation in Schlitz from the nearby Breitenbach stream since 1949, the special focus in this handbook and ready reference is on animal and microorganism occurrence and variation, as well as chemical and physical parameters. An invaluable data basis for modeling purposes for anyone dealing with stream ecology.

Documents the latest results and opinions on the causes and possible cures for this disorder. Coverage includes retroviral involvement, immunity, pathophysiology and pharmacological treatment of chronic fatigue syndrome.

An important resource that reviews the various infectious diseases that affect bats and bat populations Bats and Human Health: Ebola, SARS, Rabies and Beyond covers existing literature on viral, bacterial, protozoan, and fungal infections of bats and how these infections affect bat populations. The book also offers an overview of the potential for zoonotic transmission of infectious diseases from bats to humans or domestic animals. While most prior publications on the subject have dealt only with bat viral infections, this text closely covers a wide range of bat infections, from viral and bacterial infections to protist and fungal infections. Chapters on viral infections cover rabies, filoviruses, henipaviruses, and other RNA viruses, as well as information on bat virome studies. The book then provides information on bacterial infections–including arthropod-borne and other bacteria that affect bats–before moving on to protist infections, including apicomplexans and kinetoplastids, and fungal infections, including white-nose syndrome, histoplasma capsulatum, and other fungi. Comprehensive in scope, yet another key feature of this book is a searchable database that includes bat species, bat family, bat diet, bat location, type and classification of infecting microbes, and categories of microbes. This vital resource also: Provides a history and comprehensive overview of bat-borne diseases Incorporates information from the World Health Organization, as well as historical data from the National Libraries of Health and infectious disease journals Covers a variety of diseases including viral infections, bacterial infections, protist infections, and fungal infections Written for microbiologist, bat researchers, and conservationists, Bats and Human Health provides a comprehensive exploration of the various types of microbes that affect bats and their potential to affect human populations.

First discovered as fungal metabolites, the gibberellins were recognised as plant hormones over 50 years ago. They regulate reproductive development in all vascular plants, while their role in flowering plants has broadened to include also the regulation of growth and other developmental processes. This timely book covers the substantial and impressive recent advances in our understanding of the gibberellins and their roles in plant development, including the biosynthesis, inactivation, transport, perception and signal transduction of these important hormones. An introductory chapter traces the history of gibberellin research, describing the many discoveries that form the basis for the recent progress. The exciting emerging evidence for the interaction of gibberellin signalling with that of the other hormones is critically evaluated. The occurrence of gibberellins in fungal, bacterial and lower plant species is also discussed, with emphasis on evolution. Manipulation of gibberellin metabolism and signal transduction through chemical or genetic intervention has been an important aspect of crop husbandry for many years. The reader is presented with important information on the advances in applying gibberellin research in agriculture and horticulture. Annual Plant Reviews, Volume 49: The Gibberellins is an important resource for plant geneticists and biochemists, as well as agricultural and horticultural research workers, advanced students of plant science and university lecturers in related disciplines. It is an essential addition to the shelves of university and research institute libraries and agricultural and horticultural institutions teaching and researching plant science.

Antimicrobial resistance is arguably the greatest threat to worldwide human health. This book evaluates the roles of human water use, treatment and conservation in the development and spread of antimicrobial resistance. Designed as a companion volume to Antimicrobial Resistance in the Environment (Wiley-Blackwell, 2012), this book is a multi-disciplinary synthesis of topics related to antimicrobial resistance and wastewater treatment processes. Antimicrobial Resistance in Wastewater Treatment Processes assembles detailed discussions written by many of the world's best-known experts in microbiology, civil engineering, chemistry, environmental science, public health and related fields. The book presents a collection of subjects that includes: Current knowledge of the role of the environment in development and spread of antimicrobial resistance Chemical analysis of antibiotics in environmental samples Molecular methods for analysis of antimicrobial resistance genes Advanced wastewater treatment processes and antimicrobial resistance effects Public perception of risk related to health consequences of antimicrobial resistance Public health implications of antimicrobial resistance with focus on wastewater treatment processes Antimicrobial resistance has gained a foothold in the global consciousness as a serious public health threat. There is a much greater appreciation for the role of the environment in the dissemination of antimicrobial resistance and the effects of pollutants that can potentially promote development of resistance in bacteria. Contaminants released from wastewater treatment plants are a concern. In Antimicrobial Resistance in Wastewater Treatment Processes, readers will be guided through examinations of the current science related to this important health issue.

Principles of Virology , the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to under-stand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses.This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest.  Volume I: Molecular Biology  focuses on the molecular processes of viral reproduction, from entry through release.  Volume II: Pathogenesis and Control  addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition , is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases.

Insect Biodiversity: Science and Society brings together leading scientific experts to assess the impact insects have on humankind and the earth’s fragile ecosystems. It examines why insect biodiversity matters and how the rapid evolution of insect species is affecting us all. Insects and related arthropods make up more than 50 percent of the known animal diversity globally, yet a lack of knowledge about insects is hindering the advance of science and society. This book explores the wide variety in type and number of insect species and their evolutionary relationships. Case studies offer assessments on how insect biodiversity can help meet the needs of a rapidly expanding human population, and also examine the consequences that an increased loss of insect species will have on the world. The book concludes that a better understanding of the biology and ecology of insects is the only way to sustainably manage ecosystems in an ever changing global environment.

Each year, some two million people in the United Kingdom experience visual hallucinations. Infrequent, fleeting visual hallucinations, often around sleep, are a usual feature of life. In contrast, consistent, frequent, persistent hallucinations during waking are strongly associated with clinical disorders; in particular delirium, eye disease, psychosis, and dementia. Research interest in these disorders has driven a rapid expansion in investigatory techniques, new evidence, and explanatory models. In parallel, a move to generative models of normal visual function has resolved the theoretical tension between veridical and hallucinatory perceptions. From initial fragmented areas of investigation, the field has become increasingly coherent over the last decade. Controversies and gaps remain, but for the first time the shapes of possible unifying models are becoming clear, along with the techniques for testing these. This book provides a comprehensive survey of the neuroscience of visual hallucinations and the clinical techniques for testing these. It brings together the very latest evidence from cognitive neuropsychology, neuroimaging, neuropathology, and neuropharmacology, placing this within current models of visual perception. Leading researchers from a range of clinical and basic science areas describe visual hallucinations in their historical and scientific context, combining introductory information with up-to-date discoveries. They discuss results from the main investigatory techniques applied in a range of clinical disorders. The final section outlines future research directions investigating the potential for new understandings of veridical and hallucinatory perceptions, and for treatments of problematic hallucinations. Fully comprehensive, this is an essential reference for clinicians in the fields of the psychology and psychiatry of hallucinations, as well as for researchers in departments, research institutes and libraries. It has strong foundations in neuroscience, cognitive science, optometry, psychiatry, psychology, clinical medicine, and philosophy. With its lucid explanation and many illustrations, it is a clear resource for educators and advanced undergraduate and graduate students.

Explores the utility and potential of extremophiles in sustainability and biotechnology Many extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development. Extremophiles features outstanding articles by expert scientists who shed light on broad-ranging areas of progress in the development of smart therapeutics for multiple disease types and products for industrial use. It bridges technological gaps, focusing on critical aspects of extremolytes and the mechanisms regulating their biosynthesis that are relevant to human health and bioenergy, including value-added products of commercial significance as well as other potentially viable products. This groundbreaking guide: Introduces the variety of extremophiles and their extremolytes including extremozymes Provides an overview of the methodologies used to acquire extremophiles Reviews the literature on the diversity of extremophiles Offers tools and criteria for data interpretation of various extremolytes/extremozymes Discusses experimental design problems associated with extremophiles and their therapeutic implications Explores the challenges and possibilities of developing extremolytes for commercial purposes Explains the FDA's regulations on certain microbial bio-products that will be of interest to potential industrialists Extremophiles is an immensely useful resource for graduate students and researchers in biotechnology, clinical biotechnology, microbiology, and applied microbiology.

Written by one of the most consulted authorities on the subject, Atlas of Developmental Field Anomalies of the Human Skeleton is the pre-eminent resource for developmental defects of the skeleton. This guide focuses on localized bone structures utilizing the morphogenetic approach that addresses the origins of variability within specific developmental fields during embryonic development. Drawings and photographs make up most of the text, forming a picture atlas with descriptive text for each group of illustrations. Each section and subdivision is accompanied by brief discussions and drawings of morphogenetic development.

Take your knowledge of fishes to the next level Fishes of the World, Fifth Edition is the only modern, phylogenetically based classification of the world’s fishes. The updated text offers new phylogenetic diagrams that clarify the relationships among fish groups, as well as cutting-edge global knowledge that brings this classic reference up to date. With this resource, you can classify orders, families, and genera of fishes, understand the connections among fish groups, organize fishes in their evolutionary context, and imagine new areas of research. To further assist your work, this text provides representative drawings, many of them new, for most families of fishes, allowing you to make visual connections to the information as you read. It also contains many references to the classical as well as the most up-to-date literature on fish relationships, based on both morphology and molecular biology. The study of fishes is one that certainly requires dedication—and access to reliable, accurate information. With more than 30,000 known species of sharks, rays, and bony fishes, both lobe-finned and ray-finned, you will need to master your area of study with the assistance of the best reference materials available. This text will help you bring your knowledge of fishes to the next level. Explore the anatomical characteristics, distribution, common and scientific names, and phylogenetic relationships of fishes Access biological and anatomical information on more than 515 families of living fishes Better appreciate the complexities and controversies behind the modern view of fish relationships Refer to an extensive bibliography, which points you in the direction of additional, valuable, and up-to-date information, much of it published within the last few years Fishes of the World, Fifth Edition is an invaluable resource for professional ichthyologists, aquatic ecologists, marine biologists, fish breeders, aquaculturists, and conservationists.

Under certain scenarios on the subject of CO2 emissions, by the end of the century the atmospheric concentration could triple its pre-industrial level. The very large numerical models intended to anticipate the corresponding climate evolutions are designed and quantified from the laws of physics. However, little is generally known about these: genesis of clouds, terms of the greenhouse effect, solar activity intervention, etc. This book deals with the issue of climate modeling in a different way: using proven techniques for identifying black box-type models. Taking climate observations from throughout the millennia, the global models obtained are validated statistically and confirmed by the resulting simulations. This book thus brings constructive elements that can be reproduced by anyone adept at numerical simulation, whether an expert climatologist or not. It is accessible to any reader interested in the issues of climate change.

The deep sea covers over 60% of the surface of the earth, yet less than 1% has been scientifically investigated. There is growing pressure on deep-sea resources and on researchers to deliver information on biodiversity and the effects of human impacts on deep-sea ecosystems. Although scientific knowledge has increased rapidly in recent decades, there exist large gaps in global sampling coverage of the deep sea, and major efforts continue to be directed into offshore research. Biological Sampling in the Deep Sea represents the first comprehensive compilation of deep-sea sampling methodologies for a range of habitats. It reviews the real life applications of current, and in some instances developing, deep-sea sampling tools and techniques. In creating this book the authors have been able to draw upon the experiences of those at the ?coal face? of deep-sea sampling, expanding on the existing methodological texts whilst encompassing a level of technical detail often omitted from journal publications. Ultimately the book will promote international consistency in sampling approaches and data collection, advance the integration of information into global databases, and facilitate improved data analyses and consequently uptake of science results for the management and conservation of the deep-sea environment. The book will appeal to a range of readers, including students, early-career through to seasoned researchers, as well as environmental managers and policy makers wishing to understand how the deep-sea is sampled, the challenges associated with deep survey work, and the type of information that can be obtained.

In the era of cost cutting and lack of adequate health insurance for many patients, clinical skills and time spent with patients are not adequately compensated. Yet, these dwindling and underpaid skills – good history taking, observation of and listening to patients, and physical examination of patients – remain very essential to making and reaching a complete and accurate diagnosis. Expensive laboratory and imaging diagnostics while very relevant, should not replace these age-old skills that have served to enhance and maintain the doctor-patient relationship and human connection, a connection that is often necessary for healing. Cases in Clinical Infectious Disease Practice uses case studies to illustrate how the infectious disease clinician processes and integrates data to arrive at a diagnosis. This type of hands-on approach, invaluable in training programs, is utilized to take the reader through initial patient encounter, through the history and physical examination, to simple laboratory findings and stains, to a final diagnosis, in a way that is easily accessible to clinicians, students, and laboratory personnel working with clinical specimens. Appeals to practitioners of all levels, with focus on patients with common problems or complications of common infections without heavy technical language Emphasizes basic clinical skills including history taking, observation, epidemiology, and physical exam, as well as simple laboratory tests, explaining how they lead to a reasonable diagnosis Presents cases seen first-hand within the community setting, reflective of cases or situations a resident or student is likely to encounter in the real world after training Cases in Clinical Infectious Disease Practice is an essential resource for clinicians, graduate and medical school students, and others conducting medical and clinical microbiology or infectious disease research on real patients.

Nanoparticles are the building blocks for nanotechnology; they are better built, long lasting, cleaner, safer, and smarter products for use across industries, including communications, medicine, transportation, agriculture and other industries. Controlled size, shape, composition, crystallinity, and structure-dependent properties govern the unique properties of nanotechnology. Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications explores both the basics of and advancements in nanoparticle biosynthesis. The text introduces the reader to a variety of microorganisms able to synthesize nanoparticles, provides an overview of the methodologies applied to biosynthesize nanoparticles for medical and commercial use, and gives an overview of regulations governing their use. Authored by leaders in the field, Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications bridges the gap between biology and technology, and is an invaluable resource for students and researchers alike.

Stem cells, regenerative medicine, and translational medicine, are all areas of burgeoning basic research and clinical application. This dictionary includes the fundamental terminology of each of these areas, the major discoveries and significant scientists that comprise the history and current development of the field, as well as a number of concepts. The vocabulary is presented within the broader lexicon of developmental biology and embryology, which provides context for these three fields. Topics covered range from stem cells (embryonic, adult, and iPSCs) to teratology. The inclusion of extensive cross-referencing of the terms will enable readers to broaden their understanding of them. The Dictionary of Stem Cells, Regenerative Medicine, and Translational Medicine will provide both the basic background terminology needed by pre-health professions/biology major undergraduate students and early-stage graduate students, as well as being a valuable reference for university professors, researchers and peers in related disciplines.

Volume Two of the new guide to the study of biodiversity in insects Volume Two of Insect Biodiversity: Science and Society presents an entirely new, companion volume of a comprehensive resource for the most current research on the influence insects have on humankind and on our endangered environment. With contributions from leading researchers and scholars on the topic, the text explores relevant topics including biodiversity in different habitats and regions, taxonomic groups, and perspectives. Volume Two offers coverage of insect biodiversity in regional settings, such as the Arctic and Asia, and in particular habitats including crops, caves, and islands. The authors also include information on historical, cultural, technical, and climatic perspectives of insect biodiversity. This book explores the wide variety of insect species and their evolutionary relationships. Case studies offer assessments on how insect biodiversity can help meet the needs of a rapidly expanding human population, and examine the consequences that an increased loss of insect species will have on the world. This important text: Offers the most up-to-date information on the important topic of insect biodiversity Explores vital topics such as the impact on insect biodiversity through habitat loss and degradation and climate change With its companion Volume I, presents current information on the biodiversity of all insect orders Contains reviews of insect biodiversity in culture and art, in the fossil record, and in agricultural systems Includes scientific approaches and methods for the study of insect biodiversity The book offers scientists, academics, professionals, and students a guide for a better understanding of the biology and ecology of insects, highlighting the need to sustainably manage ecosystems in an ever-changing global environment.

Since its discovery Antarctica has held a deep fascination for biologists. Extreme environmental conditions, seasonality and isolation have lead to some of the most striking examples of natural selection and adaptation on Earth. Paradoxically, some of these adaptations may pose constraints on the ability of the Antarctic biota to respond to climate change. Parts of Antarctica are showing some of the largest changes in temperature and other environmental conditions in the world. In this volume, published in association with the Royal Society, leading polar scientists present a synthesis of the latest research on the biological systems in Antarctica, covering organisms from microbes to vertebrate higher predators. This book comes at a time when new technologies and approaches allow the implications of climate change and other direct human impacts on Antarctica to be viewed at a range of scales; across entire regions, whole ecosystems and down to the level of species and variation within their genomes. Chapters address both Antarctic terrestrial and marine ecosystems, and the scientific and management challenges of the future are explored.

A new, case-oriented and practical guide to one of the core techniques in respiratory medicine and critical care. Concise, practical reference designed for use in the critical care setting Case-oriented content is organised according to commonly encountered clinical scenarios Flow charts and algorithms delineate appropriate treatment protocols

Volume One of the thoroughly revised and updated guide to the study of biodiversity in insects The second edition of Insect Biodiversity: Science and Society brings together in one comprehensive text contributions from leading scientific experts to assess the influence insects have on humankind and the earth’s fragile ecosystems. Revised and updated, this new edition includes information on the number of substantial changes to entomology and the study of biodiversity. It includes current research on insect groups, classification, regional diversity, and a wide range of concepts and developing methodologies. The authors examine why insect biodiversity matters and how the rapid evolution of insects is affecting us all. This book explores the wide variety of insect species and their evolutionary relationships. Case studies offer assessments on how insect biodiversity can help meet the needs of a rapidly expanding human population, and also examine the consequences that an increased loss of insect species will have on the world. This important text: Explores the rapidly increasing influence on systematics of genomics and next-generation sequencing Includes developments in the use of DNA barcoding in insect systematics and in the broader study of insect biodiversity, including the detection of cryptic species Discusses the advances in information science that influence the increased capability to gather, manipulate, and analyze biodiversity information Comprises scholarly contributions from leading scientists in the field Insect Biodiversity: Science and Society highlights the rapid growth of insect biodiversity research and includes an expanded treatment of the topic that addresses the major insect groups, the zoogeographic regions of biodiversity, and the scope of systematics approaches for handling biodiversity data.

This update to the award-winning The Origins of Modern Humans: A World Survey of the Fossil Evidence covers the most accepted common theories concerning the emergence of modern Homo sapiens—adding fresh insight from top young scholars on the key new discoveries of the past 25 years. The Origins of Modern Humans: Biology Reconsidered allows field leaders to discuss and assess the assemblage of hominid fossil material in each region of the world during the Pleistocene epoch. It features new fossil and molecular evidence, such as the evolutionary inferences drawn from assessments of modern humans and large segments of the Neandertal genome. It also addresses the impact of digital imagery and the more sophisticated morphometrics that have entered the analytical fray since 1984. Beginning with a thoughtful introduction by the authors on modern human origins, the book offers such insightful chapter contributions as: Africa: The Cradle of Modern People Crossroads of the Old World: Late Hominin Evolution in Western Asia A River Runs through It: Modern Human Origins in East Asia Perspectives on the Origins of Modern Australians Modern Human Origins in Central Europe The Makers of the Early Upper Paleolithic in Western Eurasia Neandertal Craniofacial Growth and Development and Its Relevance for Modern Human Origins Energetics and the Origin of Modern Humans Understanding Human Cranial Variation in Light of Modern Human Origins The Relevance of Archaic Genomes to Modern Human Origins The Process of Modern Human Origins: The Evolutionary and Demographic Changes Giving Rise to Modern Humans The Paleobiology of Modern Human Emergence Elegant and thought provoking, The Origins of Modern Humans: Biology Reconsidered is an ideal read for students, grad students, and professionals in human evolution and paleoanthropology.

Pollinators play a vital role in ecosystem health and are essential to ensuring food security. With declines in both managed and wild pollinator populations in recent years, scientists and regulators have sought answers to this problem and have explored implementing steps to protect pollinator populations now and for the future. Pesticide Risk Assessment for Pollinators focuses on the role pesticides play in impacting bee populations and looks to develop a risk assessment process, along with the data to inform that process, to better assess the potential risks that can accompany the use of pesticide products. Pesticide Risk Assessment for Pollinators opens with two chapters that provide a biological background of both Apis and non-Apis species of pollinators. Chapters then present an overview of the general regulatory risk assessment process and decision-making processes. The book then discusses the core elements of a risk assessment, including exposure estimation, laboratory testing, and field testing. The book concludes with chapters on statistical and modeling tools, and proposed additional research that may be useful in developing the ability to assess the impacts of pesticide use on pollinator populations. Summarizing the current state of the science surrounding risk assessment for Apis and non-Apis species, Pesticide Risk Assessment for Pollinators is a timely work that will be of great use to the environmental science and agricultural research communities. Assesses pesticide risk to native and managed pollinators Summarizes the state of the science in toxicity testing and risk assessment Provides valuable biological overviews of both Apis and non-Apis pollinators Develops a plausible overall risk assessment framework for regulatory decision making Looks towards a globally harmonized approach for pollinator toxicity and risk assessment

Biochemistry and Molecular Biology of Plants, 2nd Edition has been hailed as a major contribution to the plant sciences literature and critical acclaim has been matched by global sales success. Maintaining the scope and focus of the first edition, the second will provide a major update, include much new material and reorganise some chapters to further improve the presentation. This book is meticulously organised and richly illustrated, having over 1,000 full-colour illustrations and 500 photographs. It is divided into five parts covering: Compartments, Cell Reproduction, Energy Flow, Metabolic and Developmental Integration, and Plant Environment and Agriculture. Specific changes to this edition include: Completely revised with over half of the chapters having a major rewrite. Includes two new chapters on signal transduction and responses to pathogens. Restructuring of section on cell reproduction for improved presentation. Dedicated website to include all illustrative material. Biochemistry and Molecular Biology of Plants holds a unique place in the plant sciences literature as it provides the only comprehensive, authoritative, integrated single volume book in this essential field of study.

Written by a leading expert on Aspirin-related research, this is the most comprehensive treatise on the pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind, and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This second, completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention from cardiovascular diseases and colorectal cancer.

This title is a much needed update of Barbosa's self-published Manual of Basic Techniques in Insect Histology. It is a laboratory manual of 'traditional' and 'modern' insect histology techniques, completely revised using cutting-edge methodology carried out today and includes new immunohistochemical techniques not previously looked at. Insect Histology is designed as a resource for student and professional researchers, in academia and industry, who require basic information on the procedures that are essential for the histological display of the tissues of insects and related organisms.

The diversity of animal signals has been widely documented, and the generality of animal signals also tantalizingly suggests that there are common mechanisms that have selected for their origin. However, while much progress has been made on some fronts, we still lack a general theory about why the diversity of signaling structures exist. Our compilation will directly address this gap by focusing on an exciting new arena of sexual selection, namely using functional approaches to understand signaling. This approach is rooted in the idea that many signals are designed to transmit important functional imformation that is both important for issues of male quality (and hence male competition), and female choice. The increasing use of technology in sexual selection studies has enabled researchers to test whether signaling is either constrained by, or accurately transmits information about functional capacities. Further, in animals that fight vigorously, functional capacities such as endurance or strength may make the difference between winning and losing. This volume brings together a diverse collection of researchers who are actively investigating how function and signaling are related. These researchers use both a variety of methods and taxa to study animal signaling, and we believe that this integrative view is important to open up fresh vistas for why animal signals have evolved.

Wetlands – swamp, marsh, bayou, tundra and bog – are places that are rarely visited and often misunderstood but they have, in fact, conspicuous roles in the physical, biological and cultural geography of the world. They are intrinsically beautiful environments where one may see the natural and essential values in the interaction of water, soil, vegetation, wildlife, and humans. Wetlands occur at the confluence of unique terrestrial, hydrological and climatic conditions that give rise to some of the most biodiverse regions of the world. They also play vital roles in the cycling and storage of key nutrients, materials and energy through the Earth?s system. A complete study of wetland environments requires the assessment of their physical and biological attributes, properties and functions of these ecosystems, and the economic, political and social aspects that mediate their use globally. A systems approach is taken throughout this book which emphasizes the interactions between these elements of wetland ecosystems. Moreover, selected case studies from across the world are used to illustrate wetland characteristics and circumstances. This book is intended to foster a greater awareness and appreciation of wetlands, promote a culture of conservation and wise management, and spread the knowledge that wetlands are important, indeed crucial, elements of the global environment. Our attempts to understand, manage and enhance wetlands in the twenty-first century are part of the larger effort to maintain a sustainable Earth. Readership: Introductory or intermediate level undergraduates taking courses on wetland environments Additional resources for this book can be found at: www.wiley.com/go/aber/wetland.

Selected by Forbes.com as one of the 12 best books about birds and birding in 2016 This much-anticipated third edition of the Handbook of Bird Biology is an essential and comprehensive resource for everyone interested in learning more about birds, from casual bird watchers to formal students of ornithology. Wherever you study birds your enjoyment will be enhanced by a better understanding of the incredible diversity of avian lifestyles. Arising from the renowned Cornell Lab of Ornithology and authored by a team of experts from around the world, the Handbook covers all aspects of avian diversity, behaviour, ecology, evolution, physiology, and conservation. Using examples drawn from birds found in every corner of the globe, it explores and distills the many scientific discoveries that have made birds one of our best known – and best loved – parts of the natural world. This edition has been completely revised and is presented with more than 800 full color images. It provides readers with a tool for life-long learning about birds and is suitable for bird watchers and ornithology students, as well as for ecologists, conservationists, and resource managers who work with birds. The Handbook of Bird Biology is the companion volume to the Cornell Lab’s renowned distance learning course, Ornithology: Comprehensive Bird Biology.

Biodiversity offers great potential for managing insect pests. It provides resistance genes and anti-insect compounds; a huge range of predatory and parasitic natural enemies of pests; and community ecology-level effects operating at the local and landscape scales to check pest build-up. This book brings together world leaders in theoretical, methodological and applied aspects to provide a comprehensive treatment of this fast-moving field. Chapter authors from Europe, Asia, Africa, Australasia and the Americas ensure a truly international scope. Topics range from scientific principles, innovative research methods, ecological economics and effective communication to farmers, as well as case studies of successful use of biodiversity-based pest management some of which extend over millions of hectares or are enshrined as government policy. Written to be accessible to advanced undergraduates whilst also stimulating the seasoned researcher, this work will help unlock the power of biodiversity to deliver sustainable insect pest management. Visit www.wiley.com/go/gurr/biodiversity to access the artwork from the book.

Biodiversity conservation and poverty alleviation are both important societal goals demanding increasing international attention. While they may seem to be unrelated, the international policy frameworks that guide action to address them make an explicit assumption that conserving biodiversity will help to tackle global poverty. Part of the Conservation Science and Practice Series published with the Zoological Society of London, this book explores the validity of that assumption. The book addresses a number of critical questions: Which aspects of biodiversity are of value to the poor? Does the relationship between biodiversity and poverty differ according to particular ecological conditions? How do different conservation interventions vary in their poverty impacts? How do distributional and institutional issues affect the poverty impacts of interventions? How do broader issues such as climate change and the global economic system affect the biodiversity – poverty relationship at different scales? This volume will be of interest to policy-makers, practitioners and researchers concerned with understanding the potential – and limitations – of integrated approaches to biodiversity conservation and poverty alleviation.

During the nineteenth century, ivory hunting caused a substantial decrease of elephant numbers in southern Africa. Soon after that, populations of many other large and medium-sized herbivores went into steep decline due to the rinderpest pandemic in the 1890s. These two events provided an opportunity for woodland establishment in areas previously intensively utilized by elephants and other herbivores. The return of elephants to currently protected areas of their former range has greatly influenced vegetation locally and the resulting potential negative effects on biodiversity are causing concern among stakeholders, managers, and scientists. This book focuses on the ecological effects of the increasing elephant population in northern Botswana, presenting the importance of the elephants for the heterogeneity of the system, and showing that elephant ecology involves much wider spatiotemporal scales than was previously thought. Drawing on the results of their research, the authors discuss elephant-caused effects on vegetation in nutrient-rich and nutrient-poor savannas, and the potential competition between elephants on the one hand and browsers and mixed feeders on the other. Ultimately this text provides a comprehensive review of ecological processes in African savannas, covering long-term ecosystem changes and human-wildlife conflicts. It summarises new knowledge on the ecology of the sub-humid African savanna ecosystems to advance the general functional understanding of savanna ecosystems across moisture and nutrient gradients.

An overview of the different approaches to cancer risk assessment of environmental factors – including «-omics» technologies, discussing the strengths and weaknesses of the methods in different fields. The main focus is on the carcinogenic effects of ionizing and non-ionizing radiation, demonstrating the difficulties in accurately assessing those factors that may or may not pose a significant cancer risk. The book extends the view to a broader context of risk assessment, highlighting various aspects of risk management. Written by leading experts in the field, this is a resource for policy makers and professionals in health risk assessment, and public health workers, as well as oncologists and researchers in academia. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.

This book is intended for use by natural resource managers and scientists, and students in the fields of natural resource management, ecology, and conservation biology, who are confronted with complex and difficult decision making problems. The book takes readers through the process of developing a structured approach to decision making, by firstly deconstructing decisions into component parts, which are each fully analyzed and then reassembled to form a working decision model. The book integrates common-sense ideas about problem definitions, such as the need for decisions to be driven by explicit objectives, with sophisticated approaches for modeling decision influence and incorporating feedback from monitoring programs into decision making via adaptive management. Numerous worked examples are provided for illustration, along with detailed case studies illustrating the authors’ experience in applying structured approaches. There is also a series of detailed technical appendices. An accompanying website provides computer code and data used in the worked examples. Additional resources for this book can be found at: www.wiley.com/go/conroy/naturalresourcemanagement.

There are wide inconsistencies between, and even within, countries in how community-orientated care is defined and interpreted. The analysis presented in this book take as a starting point an evidence-based balanced care model in which services are provided in community settings close to the populations served, with hospital stays being reduced as far as possible, usually located in acute wards in general hospitals. The surprising conclusion from the research is that the same problems arise in all countries, regardless of resource status, and thus the recommendations of this book apply to mental health provision everywhere. This book reviews the implementation of community-orientated care using the balanced care model. It summarizes the steps, obstacles and mistakes that have been encountered in the implementation of community mental health care worldwide and presents guidelines on how to avoid them. It proposes realistic and achievable recommendations for the development and implementation of community-orientated mental health care over the next ten years. These guidelines will be of practical use to psychiatrists and other mental health and public health practitioners at all levels worldwide, including policy makers, commissioners, funders, non-governmental organisations, service users and carers. A core message of the book is that the mental health sector will more powerfully advocate for better services in future through strong and unified alliances, especially with powerful representation from consumer/service user and carer groups. Community-orientated care draws on a wide range of practitioners, providers, care and support systems (both professional and non-professional), though particular components may play a larger or lesser role in different settings depending on the local context and the available resources, especially trained staff. Research by a WPA task force has demonstrated that most of the challenges are common and global, but with local variations. The book is therefore relevant to psychiatrists and mental health workers in developed countries who are trying to deliver better health care on reduced budgets and for those in the developing economies who are in the position to modernise their mental health care. It provides clear, concise guidance on policy and practice decisions, learning from what has and has not worked in regions in the world. The book contains many tables documenting the evidence, supported by an essential reference list, and a Key Points summary for each chapter. Highly Commended in the Psychiatry section of the 2012 BMA Book Awards.

The late Navjot Sodhi conceived this book as a way of bringing to the forefront of our conservation planning for the tropics the views of people who were actually working and living there. In its 31 chapters, 55 authors present their views on the conservation problems they face and how they deal with them. Effective long term conservation in the tropics requires the full participation of local people, organizations and governments. The human population of tropical countries is expected to grow by more than 2.5 billion people over the next several decades, with expectations of increased consumption levels growing even more rapidly than population levels; clearly there will be a need for more trained conservationists and biologists. Significant levels of local involvement are essential to conservation success, with the rights of local people fully recognized, protected and fostered by governmental and international assistance. Overarching conservation plans are necessary, but cannot in themselves lead to success. The individual experiences presented in the pages of this book will provide useful models that may serve to build better and more sustainable lives for the people who live in the tropics and lead to the continued survival of as many species and functioning ecosystems as possible.

As the impacts of anthropogenic activities increase in both magnitude and extent, biodiversity is coming under increasing pressure. Scientists and policy makers are frequently hampered by a lack of information on biological systems, particularly information relating to long-term trends. Such information is crucial to developing an understanding as to how biodiversity may respond to global environmental change. Knowledge gaps make it very difficult to develop effective policies and legislation to reduce and reverse biodiversity loss. This book explores the gap between global commitments to biodiversity conservation, and local action to track biodiversity change and implement conservation action. High profile international political commitments to improve biodiversity conservation, such as the targets set by the Convention on Biological Diversity, require innovative and rapid responses from both science and policy. This multi-disciplinary perspective highlights barriers to conservation and offers novel solutions to evaluating trends in biodiversity at multiple scales.

This innovative book provides a completely fresh exploration of bioinformatics, investigating its complex interrelationship with biology and computer science. It approaches bioinformatics from a unique perspective, highlighting interdisciplinary gaps that often trap the unwary. The book considers how the need for biological databases drove the evolution of bioinformatics; it reviews bioinformatics basics (including database formats, data-types and current analysis methods), and examines key topics in computer science (including data-structures, identifiers and algorithms), reflecting on their use and abuse in bioinformatics. Bringing these disciplines together, this book is an essential read for those who wish to better understand the challenges for bioinformatics at the interface of biology and computer science, and how to bridge the gaps. It will be an invaluable resource for advanced undergraduate and postgraduate students, and for lecturers, researchers and professionals with an interest in this fascinating, fast-moving discipline and the knotty problems that surround it.

A concise, easy-to-read source of essential tips and skills for writing research papers and career management In order to be truly successful in the biomedical professions, one must have excellent communication skills and networking abilities. Of equal importance is the possession of sufficient clinical knowledge, as well as a proficiency in conducting research and writing scientific papers. This unique and important book provides medical students and residents with the most commonly encountered topics in the academic and professional lifestyle, teaching them all of the practical nuances that are often only learned through experience. Written by a team of experienced professionals to help guide younger researchers, A Guide to the Scientific Career: Virtues, Communication, Research and Academic Writing features ten sections composed of seventy-four chapters that cover: qualities of research scientists; career satisfaction and its determinants; publishing in academic medicine; assessing a researcher’s scientific productivity and scholarly impact; manners in academics; communication skills; essence of collaborative research; dealing with manipulative people; writing and scientific misconduct: ethical and legal aspects; plagiarism; research regulations, proposals, grants, and practice; publication and resources; tips on writing every type of paper and report; and much more. An easy-to-read source of essential tips and skills for scientific research Emphasizes good communication skills, sound clinical judgment, knowledge of research methodology, and good writing skills Offers comprehensive guidelines that address every aspect of the medical student/resident academic and professional lifestyle Combines elements of a career-management guide and publication guide in one comprehensive reference source Includes selected personal stories by great researchers, fascinating writers, inspiring mentors, and extraordinary clinicians/scientists A Guide to the Scientific Career: Virtues, Communication, Research and Academic Writing is an excellent interdisciplinary text that will appeal to all medical students and scientists who seek to improve their writing and communication skills in order to make the most of their chosen career.

This dictionary is intended as a guide to the terminology used in a wide range of animal-related programmes of study including agriculture, animal care, animal management, animal production, animal welfare, veterinary nursing, wildlife conservation and zoo biology. In total it contains over 5,300 entries. It contains a wide range of terms used in the fields of veterinary science, physiology and zoology, as students whose primary interests are animal welfare or zoo biology also need to have some understanding of disease, how animal bodies function and how animals are classified. It also contains some legal terms, and reference to some legal cases, to help students understand how the protection, use and conservation of animals is regulated by the law. Some people, famous animals, literature and films have influenced the way we think about, and behave towards, animals. For this reason, the book includes references to important books about animals, famous animals who have starred in films or been the subject of scientific studies, along with short biographies of famous scientists and others who have studied animals or established conservation or animal welfare organisations.

Loss of biodiversity is among the greatest problems facing the world today. Conservation and the Genetics of Populations gives a comprehensive overview of the essential background, concepts, and tools needed to understand how genetic information can be used to conserve species threatened with extinction, and to manage species of ecological or commercial importance. New molecular techniques, statistical methods, and computer programs, genetic principles, and methods are becoming increasingly useful in the conservation of biological diversity. Using a balance of data and theory, coupled with basic and applied research examples, this book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, the interpretation of genetic data from natural populations, and how these can be applied to conservation. The book includes examples from plants, animals, and microbes in wild and captive populations. This second edition contains new chapters on Climate Change and Exploited Populations as well as new sections on genomics, genetic monitoring, emerging diseases, metagenomics, and more. One-third of the references in this edition were published after the first edition. Each of the 22 chapters and the statistical appendix have a Guest Box written by an expert in that particular topic (including James Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, and Lisette Waits). This book is essential for advanced undergraduate and graduate students of conservation genetics, natural resource management, and conservation biology, as well as professional conservation biologists working for wildlife and habitat management agencies. Additional resources for this book can be found at: www.wiley.com/go/allendorf/populations.

Population ecology has matured to a sophisticated science with astonishing potential for contributing solutions to wildlife conservation and management challenges. And yet, much of the applied power of wildlife population ecology remains untapped because its broad sweep across disparate subfields has been isolated in specialized texts. In this book, L. Scott Mills covers the full spectrum of applied wildlife population ecology, including genomic tools for non-invasive genetic sampling, predation, population projections, climate change and invasive species, harvest modeling, viability analysis, focal species concepts, and analyses of connectivity in fragmented landscapes. With a readable style, analytical rigor, and hundreds of examples drawn from around the world, Conservation of Wildlife Populations (2nd ed) provides the conceptual basis for applying population ecology to wildlife conservation decision-making. Although targeting primarily undergraduates and beginning graduate students with some basic training in basic ecology and statistics (in majors that could include wildlife biology, conservation biology, ecology, environmental studies, and biology), the book will also be useful for practitioners in the field who want to find – in one place and with plenty of applied examples – the latest advances in the genetic and demographic aspects of population ecology. Additional resources for this book can be found at: www.wiley.com/go/mills/wildlifepopulations.

In Alternative Ecological Risk Assessment the author, Lawrence V. Tannenbaum, provides a critical review of current practices in the ecological risk assessment field and proposes alternatives that are supported by established science and keen observation. It is hoped that this approach will pave the way to a greater understanding of what appropriate and useful ecological assessment for contaminated sites should entail. He demonstrates that in most cases current practices do not provide for an assessment of ecological risk, and moreover, that endeavoring to assess ecological risk is actually an unnecessary undertaking at conventional hazardous waste sites. (He states, for example, that the concept of scale is often ignored by practitioners, questions why animals like deer are routinely assessed at 5-acre sites, and challenges the ecotoxicology data currently used.) The book is aimed at students and professionals in the fields of environmental science, ecology, ecotoxicology, and health risk assessment.

Exercise Therapy in the Management of Musculoskeletal Disorders covers the fundamentals of using exercise as a treatment modality across a broad range of pathologies including osteoarthritis, inflammatory arthropathies and osteoporosis. As well as offering a comprehensive overview of the role of exercise therapy, the book evaluates the evidence and puts it to work with practical ideas for the management of musculoskeletal disorders in different areas of the body, for differing pathologies and for a range of patients. Part 1 introduces the reader tothe role of exercise in managing musculoskeletal disorders and covers measurement and assessment. Part 2 looks at the regional application of exercise therapy with chapters on areas of the body such as the cervical spine, the shoulder complex and the knee. Part 3 examines specific populations: the developing child, the cardiac and respiratory patient, obesity and osteoporosis. Exercise Therapy in the Management of Musculoskeletal Disorders is an invaluable resource for student physiotherapists as well as clinicians designing rehabilitation programmes for their patients. KEY FEATURES Concise and comprehensive Team of expert contributors Offers practical guidance Evaluates the evidence

A comprehensive account of the seal’s migratory patterns, methods of hunting and patterns of reproduction.While seals are a perennial favourite among visitors to zoos for their playful and engaging behaviour, less is known about their actions in natural habitats. Based on extensive field observations, this thoroughly illustrated volume in The New Naturalist Series is one of the most authoritative studies of its kind. The late Professor Hewer shows how recent discoveries for determining the age of seals have greatly contributed to research in the subject and he presents a comprehensive account of the seal’s migratory patterns, methods of hunting for food, movements and patterns of reproduction. As the large colonies of seals indigenous to British waters constitute and important segment of the world’s seal population, Professor Hewer’s findings will be helpful to all interested in seal behaviour, and conservation.Professor Hewer researched seal behaviour for over twenty years, did extensive field work in seals and published several articles on his findings. He was Emeritus Professor at the University of London and served with the British government’s Ministry of Agriculture and Ministry of Food.

Ants should provide both the amateur naturalist and the professional zoologist with a valuable source of reference, and a fascinating account of the lives of an intriguing group of insects.Ants have always exercised a fascination that extends beyond the world of biology. They have attracted the attention of poets and dramatists, and also of those philosophers and political theorists who have envied their apparent industry and rigid and complex communal organisation. The social life of ants is indeed extraordinary. It forms the basis of their entire lives; an ant on its own has no chance of survival. Ants are the only group of insects in which there are no solitary species at all.In this book Dr Brian, the country's leading authority on ants, brings together the results of recent research (much of it his own) into the zoology, ecology and social life of the group. Dr Brian begins by discussing the relationship of ants to other insects, their anatomy and physiology, and then turns to the different species of British ant (with an identification key), feeding, including aphid 'farming' and the specialised role of the workers in acting as travelling food containers for the nest itself, the rearing of the young and the different caste systems (including the life history of the queen), the ecological significance of ants, and the role they play in the lives of other animals. Particular attention is paid to the importance of communication in the ant society, and there is a complete section of distribution maps – one for each of the 47 British Species – compiled according to the latest available data. There are 16 plates of black and white photographs and two colour plates of ant species specially painted for this volume by Gordon Riley.This book should provide both the amateur naturalist and the professional zoologist with a valuable source of reference, and a fascinating account of the lives of an intriguing group of insects.

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer.For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease – it is inevitable. But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable. In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan – he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick – a circuit designed to halt reproduction in order to repair damage to the genome –has enabled earth’s early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death. But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Readers will discover how a few simple lifestyle changes – like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy – can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like – and what will need to change – when we are all living well to 120 or more. Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. LIFESPAN is destined to be the biggest book on genes, biology, and longevity of this decade.