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THE encyclopedic guide to hepatology – for consultation by clinicians and basic scientists Previously the Oxford Textbook of Clinical Hepatology, this two-volume textbook is now with Blackwell Publishing. It covers basic, clinical and translational science (converting basic science discoveries into the practical applications to benefit people). Edited by ten leading experts in the liver and biliary tract and their diseases, along with outstanding contributions from over 200 international clinicians, this text has global references, evidence and extensive subject matter – giving you the best science and clinical practice discussed by the best authors. It includes unique sections on: Symptoms and signs in liver disease Industrial diseases affecting the liver The effects of diseases of other systems on the liver The effects of liver diseases on other systems It’s bigger and more extensive than other books and discusses new areas in more depth such as stem cells, genetics, genomics, proteomics, transplantation, mathematics and much more. Plus, it comes with a fully searchable CD ROM of the entire content. Click here to view a sample chapter on the liver and coagulation

The late Arthur Rook established the Textbook of Dermatology as the most comprehensive work of reference available to the dermatologist and it enjoys instant name recognition. Each subsequent edition has been expanded as the subject has developed and the book remains the ultimate source of clinical information for the trainee and practising dermatologist alike. Rook's Textbook of Dermatology covers all aspects of skin disease from basic science through pathology and epidemiology to clinical practice. Long recognized for its unparalleled coverage of diagnosis, this clinical classic earned its reputation as a definitive source of information. New features of this Seventh Edition include: Two new Editors, Neil Cox and Christopher Griffiths, join the team Every chapter is updated and several are completely rewritten from scratch Completely new chapter on AIDS and the Skin Traditional emphasis on diagnosis preserved More coverage of treatment in each of the disease-specific chapters

Over the past twenty years, thousands of physicians have come to depend on Yamada’s Textbook of Gastroenterology. Its encyclopaedic discussion of the basic science underlying gastrointestinal and liver diseases as well as the many diagnostic and therapeutic modalities available to the patients who suffer from them was—and still is—beyond compare. This new edition provides the latest information on current and projected uses of major technologies in the field and a new section on diseases of the liver. Plus, it comes with a fully searchable CD ROM of the entire content.

The most comprehensive textbook in the field edited by the founding father of endourology returns for a new edition. In full colour throughout and packed with surgical teaching videos, this is an essential purchase for all urologists wishing to master their skills.

The encyclopedic guide to the pancreas for practicing clinicians and surgeons In the past decade extraordinary developments in diagnostic and therapeutic radiology and endoscopy have been coupled with major advances in surgical techniques and basic sciences. As a result the management of pancreatic disorders is now handled by a multidisciplinary team. This book shows you how to achieve superior patient management by taking the team approach to in-hospital care. Fully revised and updated, this new edition of The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery details the latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known pancreatic disorders. The Editor and author team are leading pancreatologists of high international repute and they present global best-practice and evidence-based knowledge in this comprehensive reference. A timely section on early and late outcome data considers the benefits of management including chemotherapy and immune therapy. Incorporating evidence-based data, the book also focuses on early diagnosis, limited surgical treatment, oncology, treatment results and the option of transplantation. This new edition contains more than 400 illustrations, line drawings and radiographs to provide a step-by-step approach to endoscopic techniques and surgical procedures. With The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, Second Edition, you can achieve a greater understanding of current diagnostic, medical and surgical treatment principles in one authoritative reference point.

This outstanding reference source on bone marrow transplantation has become recognised as the bible in the field. This fourth edition has been fully revised to reflect latest developments, and now features over 500 illustrations, including a colour plate section. The need for this new edition cannot be overstated – more than 13,000 new cases per year of haematopoietic stem cell transplantation have been reported to the International Bone Marrow Transplant Registry The original editor, Donnall Thomas, was a pioneer in stem cell research and won the 1990 Nobel Prize for his discoveries concerning organ and cell transplantation in the treatment of human diseases. The book also now includes a fully searchable CD with PDFs of the entire content.

Now in its Fifth Edition, Crofton and Douglas's Respiratory Diseases has firmly established itself as the leading clinical textbook on diseases of the chest. Presented, for the first time, as a two-volume set, this classic text has been completely rewritten and greatly expanded. Extensive revisions ensure that these volumes present an up-to-date review of all aspects of lung disease . The contributions of some 18 leading authorities ensure that each area is comprehensively covered and new to this edition are chapters on the genetics of lung disease, smoking, air pollution, sleep apnoea, diving, lung transplantation and medico-legal aspects. The changes in content reflect the pace of change in the areas concerned not only in terms of understanding of the disease processes but also their treatment. The single chapter on asthma that appeared in previous editions, has now been expanded into three chapters covering epidemiology, mechanisms and management, reflecting the enormous research effort currently underway following a marked increase in the incidence of this disease in recent years. This new edition continues to provide an excellent reference both for the trainee and specialist in respiratory medicine, as well as the general physician. It will be extremely useful on the ward and in the office, where clinical problems arise and questions are asked which need clear answers.

The third edition of this highly regarded text continues to provide a comprehensive resource for pediatric dermatologists. The book offers evidence-based diagnosis and treatment recommendations and covers both common and rare conditions, including emerging conditions and research, especially at the genetic level. A refreshing new text design makes the book more accessible, and new editors and contributors bring a distinctly international perspective to the work.

Morson and Dawson's Gastrointestinal Pathology is one of the 'Gold Standards' of pathology textbooks. It has been completely revised to incorporate the latest advances in this rapidly evolving field including the developments in gastric cancer and Helicobacter pylori and the revised classification of other common gastrointestinal conditions. This new edition features a wealth of new material presented in full colour for the first time.

The only international clinical textbook for COPD – one of the top 5 causes of death and disability worldwide The only COPD textbook to include the latest national and international guidelines and the newer therapeutic agents in COPD treatment International team of contributors covers all aspects of COPD – from physiology and epidemiology to diagnosis and treatment Everything the busy physician needs to understand, diagnose and treat the COPD patient: – Structure and physiology of the respiratory system – Clinical considerations and allied conditions – Therapy (including current and developing treatments) – Diagnostic tests used in daily practice

The rapidly growing population of adults surviving with congenital heart lesions along with the success of interventional cardiology in the child and adolescent has spawned an incredible interest in adapting the technology for the adult congenital patients. Dr. Mullins, a pioneer in this area, has written an outstanding reference which covers all aspects of performing diagnostic and therapeutic cardiac catheterization procedures on patients of all ages. This illustrated book details the equipment and techniques for performing safe and successful procedures, with a strong emphasis on avoiding complications. It also includes the requirements of a catheterization laboratory for congenital heart patients, as well as guidance for setting up and operating such a laboratory. Cardiac Catheterization in Congenital Heart Disease serves as an essential manual for pediatric and adult interventional cardiologists worldwide.

The definitive guide to the science, diagnosis and treatment of all known nail diseases The fifth edition of Baran & Dawber’s Diseases of the Nails and their Management continues to offer an encyclopedic account of the human nail that is unparalleled in its detail and scope. With contributions from some of the world’s leading dermatologists, the book’s exhaustive coverage encompasses the cosmetic and therapeutic management of every form of nail disease. High-quality images and diagrams illustrate and enhance this essential reference guide, while easy-to-navigate sub-chapters help you to find the information you need quickly and accurately. This book: Is edited by Professor Robert Baran – the world’s leading expert on the human nail – together with a team of world-renowned experts from across Europe and North America Provides clinical information on all nail diseases Aids differential diagnosis by color, shape, and location Contains over 1,500 images Includes access to a companion website featuring downloadable images and videos of nail procedures Whether they are new to the field or have been practicing for years, dermatologists, podiatrists, and all of those managing patients with nail diseases should have a copy of Baran & Dawber’s Diseases of the Nails and their Management at their disposal.

This valuable new addition to the Encyclopaedia of Sports Medicine series provides a comprehensive and logical look at the principles and mechanisms of endocrinology as related to sports and exercise. It looks at growth hormone factors involved in exercise and the endocrinology of sport competition. It considers various factors and stresses on the body that may alter sporting performance. It covers topics from the acute responses and chronic adaptations of the human endocrine system to the muscular activity involved in conditioning exercise, physical labor, and sport activities. This book is an essential reference for helping to plan better programs of physical fitness, to prepare for sports competitions, and to manage the medical care of athletes.

This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states It provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders. Novel and potentially controversial Will inspire future research directions

An interdisciplinary reference book for the diagnosis and treatment of gallbladder and bile duct diseases With recent developments in the management of hepatobiliary diseases including liver transplantation, this new edition aids all members of the team by addressing both the biliary indications for and biliary complications of these procedures. It's divided into three sections on anatomy, pathophysiology, and epidemiology; diagnostic and therapeutic approaches including the latest therapeutic modalities; and specific conditions. Includes more than 250 illustrations for rapid reference. Each chapter now has a Q&A section and begins with a list of objectives outlining the chapter’s goals. In addition, a number of new imaging modalities are presented in this new edition. It takes an integrated medical, surgical and radiological approach, making this invaluable to all members of the team who deal with complications of liver transplantation and the management of patients.

The young ob/gyn patient presents unique problems different from the mature woman but which training often neglects. This user-friendly, practical book provides generous coverage of all aspects of pre-womanhood gynecology. Ranging from the commonest problems to the less common but urgent, it emphasizes diagnosis, special care and management throughout.

Textbook and Color Atlas of Traumatic Injuries to the Teeth encompasses the full scope of acute dental trauma, including all aspects of inter-disciplinary treatment. This fourth edition captures the significant advances which have been made in the subject of dental traumatology, since the publication of the last edition more than a decade ago. The comprehensive nature of the book is designed to appeal to distinguished clinicians and scholars of dental traumatology, whether they be oral surgeons, pediatric dentists, endodontists, or from a related specialist community.

Biomechanics in Sport is a unique reference text prepared by the leading world experts in sport biomechanics. Over thirty chapters cover a broad spectrum of topics, ranging from muscle mechanics to injury prevention, and from aerial movement to wheelchair sport. The biomechanics of sports including running, skating, skiing, swimming, jumping in athletics, figure skating, ski jumping, diving, javelin and hammer throwing, shot putting, and striking movements are all explained.

A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts. As such, this is the first volume to summarize the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function of virulence factors. Further chapters cover cross-talk between meningococci and host cells, genomics and immunobiology. The result is a standard handbook for all scientists working in the field. While aimed at advanced specialists in basic research, epidemiologists, public health workers, vaccine developers and clinicians, the book is equally appropriate as introductory reading for graduates embarking on their career in this field.

The aim of this book has always been to give guidance on the diagnosis and treatment of ocular motility disorders based on clinical experience, as opposed to a comprehensive treatise on the subject drawn from the primary literature. The Third Edition sees a new team of authors who have kept very much to this priniciple in their nevertheless thorough revision of the book. Whilst there are no new chapters as such, the immediate impact of the revision is in the improved page layout with increased use of diagrams and flowcharts. There are new sections on feigned visual loss in adults and children, the management of residual defects and the section on botulinum toxin treatment in chapter 8 will be re-written to take account of the great advances in this form of treatment.

Provides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day. Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell differentiation, autophagy, and apoptosis. The text goes on to explore how these processes are disturbed in the various diseases of the bone marrow, blood, and lymphoid systems. Helps solve difficult diagnostic challenges and covers complex principles using highly illustrative, full-color images Explores all aspects of benign and malignant hematology, including blood transfusion and coagulation with extensive coverage of the pathogenesis of common clinical entities Provides a quick and easy reference of key diagnostic issues in a comprehensive yet concise format Includes and illustrates the WHO Classification of Hematologic Malignancies Illustrates the new knowledge of the molecular basis of inherited and acquired blood diseases Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease is the must-have resource for both trainee and practising hematologists, and for every department of hematology.

Textbook and Color Atlas of Traumatic Injuries to the Teeth, Fifth Edition encompasses the full scope of acute dental trauma, including all aspects of interdisciplinary treatment. New edition of the definitive reference on dental traumatology Thoroughly revised and updated with a modern look and feel Eight new chapters on innovative developments in the field Contributions from world-renowned authors and editors Linked to dentaltraumaguide.org with a specific chapter on how the book complements the online guide

Some foods, as well as contributing essential nutrients to the body, also contain additional components that improve disease resistance and general health status over and above that induced by ingestion of conventional foods. The so-called functional foods, and prebiotics and probiotics exemplify the relationship that exists between nutrition, the gut (the largest element of the body’s immune system) and its flora, immunology and health. This important book contains chapters covering the basic principles of nutrition, gut microecology and immunology, as well as chapters which discuss the way in which this knowledge may be used to explain the positive and negative effects of food consumption, metabolism, probiotics and prebiotics. Food hypersensitivity and allergic reactions, carcinogenesis, and the role of nutrition in the reduced immunity of the aged are also discussed in detail. The editors of this exciting and informative book, who between them have a vast wealth of knowledge of the area, have drawn together and carefully edited international contributions from many well known and respected workers in the area. Gut Flora, Nutrition, Immunity and Health provides essential information for a range of professionals including nutritionists, dietitians, food scientists, microbiologists, gastroenterologists, immunologists and all personnel working in the development and use of functional foods and supplements, prebiotics and probiotics. Libraries in universities and research establishments where these subjects are studied and taught, and pharmaceutical and food companies should have multiple copies of this very useful book on their shelves. Roy Fuller is a consultant in gut microecology, based in Reading, UK; Gabriela Perdig?n is based at the Centro de Referencia para Lactobacillus (CERELA) and at the Faculty of Biochemistry, Chemistry and Pharmacy of Tucuman University, Argentina.

This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology. The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The Scripps Research Institute, has assembled an all-star team of authors to report on the latest research, technologies, and applications. Following an introductory chapter, the book goes on to cover such topics as cellular mechanisms of autoantibody production, clinical and diagnostic usefulness in human disease, and animal models used to study the elicitation of autoantibodies. The whole is rounded off with a look at future perspectives. With its comprehensive coverage, this volume will appeal not only to immunologists and clinicians but also to cell and molecular biologists.

This exciting and important book covers the impact on demography of the nutrition of populations, offering the view that the change from the hunter-gatherer to an agricultural life-style had a major impact on human demography, which still has repercussions today. Demography and Nutrition takes an interdisciplinary approach, involving time-series analyses, mathematical modelling, aggregative analysis and family reconstitution as well as analysis of data series from Third World countries in the 20th Century. Contents include details and analysis of mortality oscillations, food supplies, famines, fertility and pregnancy, infancy and infant mortality, ageing, infectious diseases, and population dynamics. The authors, both well known internationally for their work in these areas, have a great deal of experience of population data gathering and analysis. Within the book, they develop the thesis that malnutrition, from which the bulk of the population suffered, was the major factor that regulated demography in historical times, its controlling effect operated via the mother before, during and after pregnancy. Demography and Nutrition contains a vast wealth of fascinating and vital information and as such is essential reading for a wide range of health professionals including nutritionists, dietitians, public health and community workers. Historians, social scientists, geographers and all those involved in work on demography will find this book to be of great use and interest. Libraries in all university departments, medical schools and research establishments should have copies of this landmark publication available on their shelves.

First major evidence-based text in adult respiratory medicine Comprehensive, authoritative summary of the best treatments for the major respiratory diseases Compiled by specialists from the Cochrane Airways Management Group Easy-to-use format, with key clinical implications summarised in each chapter Kept up-to-date online Compiled by specialists from the Cochrane Collaboration Airways Management Group, Evidence-based Respiratory Medicine is the first major evidence-based text in adult respiratory medicine. Providing a comprehensive summary of the best treatments for the most important respiratory diseases, some of the world's leading physicians review the evidence for a broad range of treatments using evidence-based principles. Essential information is presented in an easy-to-understand format, with the most important clinical implications summarised in each chapter. Evidence-based Respiratory Medicine tackles the big clinical questions in diagnosis and treatment, presenting treatment options which take into account the individual patient's needs. Evidence-Based Series: Evidence-based Respiratory Medicine, part of the acclaimed series BMJ Evidence-based medicine textbooks that have revolutionised clinical medicine literature, comes with a fully searchable CD-ROM of the whole text. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

There has been very little written on the interaction of the liver and kidney. This book addresses the increasing incidence and significance of diseases, such as ascites, renal dysfunction, cirrhosis and hypertension where both organs are involved. This textbook is essential, even for confirmed practitioners and contains current information regarding treatment and therapy for patients with cirrhosis and ascites, clearly and effectively presented by the top international experts within this field. The second edition is entirely revised and updated and places greater emphasis on therapy.

Ultrasound enables us to monitor the cardiovascular system and brain responses to treatment in real time; a genuine blessing on the route to more effective stroke therapies, and an invaluable tool with which to tailor treatment when available evidence is meagre. Ultrasound is a vital observational tool, yet a probe needs a scientist to point it in the right direction and a skilled physician to synthesise scientific data with practical management strategies. This book, intended for clinicians who are eager to learn and prepared to observe, focusses on the examination of stroke patients, the interpretation of ultrasound studies, and the application of cerebrovascular ultrasound to management and treatment strategies. Produced by an international team of contributors and edited at the University of Texas, one of the major world centres in stroke research, it is a practical volume that can be used by beginners to learn the principles of ultrasound testing, by advanced users to learn differential diagnosis, and by clinicians (non-sonographers) who treat stroke patients. The latter will gain knowledge on how to apply ultrasound, and what to expect from it in terms of clinical decision making and treatment selection.

A comprehensive and highly illustrated reference on current topics in esthetic dental implant therapy Advances in Esthetic Implant Dentistry provides a current, comprehensive overview of esthetic implant therapy. Offering innovative step-by-step protocols for surgical techniques and case studies, the book presents practical, clinically oriented guidance firmly anchored in solid scientific research. A companion website provides videos of clinical procedures and follow-up case studies. The book emphasizes the physiology of labial plate of bone and its influence to the overall fate of implant placement in fresh extraction sites, including several cutting-edge techniques to restore and treat deficient labial plate of bone. A novel chapter offers a solid protocol to diagnose, categorize, and treat implant-related gingival recession predictably. Highlights novel esthetic protocols in dental implantology, applying the latest advances in clinical techniques to real-world dentistry Follows up on treatment outcomes, presenting results up to seven years later Provides reliable, evidence-based bone regenerative methods Illustrates procedures step by step, with more than 2500 clinical photographs Features a companion website with videos of clinical procedures and follow-up case studies Advances in Esthetic Implant Dentistry is an indispensable clinical companion for practitioners and students of periodontics, prosthodontics, oral and maxillofacial surgery, and general dentistry, bringing the reader new horizons in esthetic dentistry.

Diagnosis and Management of Hypertrophic Cardiomyopathy is a unique, multi-authored compendium of information regarding the complexities of clinical and genetic diagnosis, natural history, and management of hypertrophic cardiomyopathy (HCM)—the most common and important of the genetic cardiovascular diseases—as well as related issues impacting the health of trained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and with major contributions from all of the international experts in this field, this book provides a single comprehensive source of information concerning HCM. Recent advances in the field are discussed, including the importance of left ventricular outflow tract obstruction, the use of implantable defibrillators for the prevention of sudden death in young people, definition of the genetic basis for HCM and its role in clinical diagnosis and risk stratification, the development of more precise strategies for assessing the level of risk for sudden death among all patients with HCM, and the evolution of invasive interventions for heart failure symptoms, such as surgical management and its alternatives (alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field, representing diverse viewpoints regarding this heterogeneous disease and related issues in athletes Information to dispel misunderstandings regarding issues associated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on the topic

Coaching Science and Coaching Studies courses are appearing in increasing numbers in many universities. The textbooks used in most of these courses are either theoretically based sports science texts or practically based coaching books. The former are generally lacking in application while the latter rarely have any scientific input. The reader is, therefore, left to make the links themselves. Coaching Science will bridge that gap covering both theory and practice and, most important, showing how theory informs practice. The book will be multi- and, to some extent, inter-disciplinary, as it is not possible to examine the interaction between coach, performer and task from a single discipline perspective. Each chapter will include overviews of the main theories, but the bulk of the material will be concerned with how such theories can be applied in practice. Good and frequent use of examples will be provided. Throughout, the student will be given problems to solve. At the end of each chapter there will be revision notes, recommended readings and questions on chapter content.

This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international look at all aspects of the origins, consequences and treatment of obesity.

The new international standard reference work for sexual medicine Written under the auspices of the International Society for Sexual Medicine, (www.issm.info), the leading professional society in sexual medicine and founder of the most influential journal in the field, The Journal of Sexual Medicine, published by Blackwell Publishing Comprehensive coverage of the full range of diagnostic and treatment options in all aspects of male and female sexual dysfunctions Provides information on recent progress in pharmacologic approaches, including the highly successful drug treatments for ED Useful for any part of the patient-clinician consultation, from gathering symptoms to diagnosis to treatment to reports on potential and developing treatments

A working guide to the use of drugs in the treatment of urological disease The content is arranged so that the busy urologist can go quickly and easily to the relevant section Coverage of treatment is evidence-based It is the only current book on drug treatment in urology Great strides have been made in the understanding of the scientific basis of urological conditions and this has allowed the development of drugs for a wide variety of urological disorders. This book provides urologists with a working guide to the rapidly growing armoury of drugs available to them.

Evidence-based Paediatric and Adolescent Diabetes brings together an international group of paediatric diabetes specialists to address the cause, course and complications of all types of diabetes. From a careful review of the latest research, they propose the best possible evidence-based recommendations for the care of children and the youth with diabetes. The text provides the reader with an understanding across three different levels: • Reviews how strong the evidence is for recommending one approach over another • Highlights areas where evidence is not based on the types of studies needed to provide ‘highgrade recommendations’, but where there is a general consensus as to the most sensible approach • Identifies the issues that remain inadequately addressed such that no definitive recommendations can be made As the incidence of type 1 diabetes mellitus continues to increase worldwide, and type 2 is being seen in more young people, this timely volume will help a wide range of health care professionals deliver the best possible care to their young patients.

The relationship of metabolic diseases to cardiovascular disease (CVD) is reaching epidemic proportions. This relates mostly to the increasing prevalence of obesity, the metabolic syndrome and type 2 diabetes. This book outlines and addresses the metabolic factors and related diseases that contribute to CVD, including brief introductions to metabolic pathways including lipid and lipoprotein metabolism, macronutrient fuel partitioning, insulin action and body weight regulation. Mechanisms that relate to becoming obese, maintenance of the obese state, the dyslipidemias, and glucose intolerance/diabetes are also addressed, and the importance of interventions that reduce metabolic risk factors and CVD are covered.

Prevention is the first line of defence in the fight against infection. As antibiotics and other antimicrobials encounter increasing reports of microbial resistance, the field of decontamination science is undergoing a major revival. A Practical Guide to Decontamination in Healthcare is a comprehensive training manual, providing practical guidance on all aspects of decontamination including: microbiology and infection control; regulations and standards; containment, transportation, handling, cleaning, disinfection and sterilization of patient used devices; surgical instrumentation; endoscopes; and quality management systems. Written by highly experienced professionals, A Practical Guide to Decontaminationin Healthcare comprises a systematic review of decontamination methods, with uses and advantages outlined for each. Up-to-date regulations, standards and guidelines are incorporated throughout, to better equip healthcare professionals with the information they need to meet the technical and operational challenges of medical decontamination. A Practical Guide to Decontaminationin Healthcare is an important new volume on state-of-the-art decontamination processes and a key reference source for all healthcare professionals working in infectious diseases, infection control/prevention and decontamination services.

Dental Management of Sleep Disorders focuses on the dentist’s role in treating patients with sleep problems, chiefly sleep disordered breathing and bruxism. A practical clinical book, Dental Management of Sleep Disorders highlights the background to these problems, discusses the dentist’s role in their diagnosis and treatment, and outlines clinical strategies and guidance. The book features a full discussion of the use of appliances, an overview of current treatment modalities, and investigates the relationship of sleep disorders to dental and orofacial causes.

Studies in bioequivalence are the commonly accepted method to demonstrate therapeutic equivalence between two medicinal products. Savings in time and cost are substantial when using bioequivalence as an established surrogate marker of therapeutic equivalence. For this reason the design, performance and evaluation of bioequivalence studies have received major attention from academia, the pharmaceutical industry and health authorities. Bioequivalence Studies in Drug Development focuses on the planning, conducting, analysing and reporting of bioequivalence studies, covering all aspects required by regulatory authorities. This text presents the required statistical methods, and with an outstanding practical emphasis, demonstrates their applications through numerous examples using real data from drug development. Includes all the necessary pharmacokinetic background information. Presents parametric and nonparametric statistical techniques. Describes adequate methods for power and sample size determination. Includes appropriate presentation of results from bioequivalence studies. Provides a practical overview of the design and analysis of bioequivalence studies. Presents the recent developments in methodology, including population and individual bioequivalence. Reviews the regulatory guidelines for such studies, and the existing global discrepancies. Discusses the designs and analyses of drug-drug and food-drug interaction studies. Bioequivalence Studies in Drug Development is written in an accessible style that makes it ideal for pharmaceutical scientists, clinical pharmacologists, and medical practitioners, as well as biometricians working in the pharmaceutical industry. It will also be of great value for professionals from regulatory bodies assessing bioequivalence studies.

A hands-on guide to using statistics in health research, from planning, through analysis, and on to reporting A Practical Approach to Using Statistics in Health Research offers an easy to use, step-by-step guide for using statistics in health research. The authors use their experience of statistics and health research to explain how statistics fit in to all stages of the research process. They explain how to determine necessary sample sizes, interpret whether there are statistically significant difference in outcomes between groups, and use measured effect sizes to decide whether any changes are large enough to be relevant to professional practice. The text walks you through how to identify the main outcome measure for your study and the factor which you think may influence that outcome and then determine what type of data will be used to record both of these. It then describes how this information is used to select the most appropriate methods to report and analyze your data. A step-by-step guide on how to use a range of common statistical procedures are then presented in separate chapters. To help you make sure that you are using statistics robustly, the authors also explore topics such as multiple testing and how to check whether measured data follows a normal distribution. Videos showing how to use computer packages to carry out all the various methods mentioned in the book are available on our companion web site. This book: • Covers statistical aspects of all the stages of health research from planning to final reporting • Explains how to report statistical planning, how analyses were performed, and the results and conclusion • Puts the spotlight on consideration of clinical significance and not just statistical significance • Explains the importance of reporting 95% confidence intervals for effect size • Includes a systematic guide for selection of statistical tests and uses example data sets and videos to help you understand exactly how to use statistics Written as an introductory guide to statistics for healthcare professionals, students and lecturers in the fields of pharmacy, nursing, medicine, dentistry, physiotherapy, and occupational therapy, A Practical Approach to Using Statistics in Health Research:From Planning to Reporting is a handy reference that focuses on the application of statistical methods within the health research context.

Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques

As advanced practices and role extension within the healthcare sector continues unabated, increasingly practitioners seek ways to widen their professional remit and develop and add to their skills. Interpreting Trauma Radiographs provides a unique guide to enable radiographers and trained healthcare professionals to confidently and competently interpret and report on radiographic images. Designed specifically for radiographers, casualty (accident and emergency) medical officers and trainees, and other health professionals who regularly encounter trauma radiography as part of their work, this book brings together expert contributions on the clinical, medical, legal and scientific aspects of radiographic interpretation and reporting, promoting a thorough understanding of both the general framework of reporting and the detail of image interpretation. The book is divided into two sections. The first section deals with the overall framework of image reporting and interpretation: the radiologist’s perspective, the legal aspects, scientific background and the psychological nature of perception and interpretation. The second section focuses on image interpretation of regional anatomy, presented to support both reporting practitioners in training and those more experienced in reporting practice. Interpreting Trauma Radiographs is an invaluable companion for qualified radiographers, radiographers in training, casualty medical officers, and other healthcare professionals, such as nurse practitioners, aspiring to interpret and report on radiographic images.

This book forms part of a series entitled Promoting Partnership for Health published in association with the UK Centre for the Advancement of Interprofessional Education (CAIPE). The series explores partnership for health from policy, practice and educational perspectives. Whilst strongly advocating the imperative driving collaboration in healthcare, it adopts a pragmatic approach. Far from being starry eyed, the series alerts readers to the pitfalls and ways to avoid them. ____________________________________________________________________________________ International Perspectives on Health and Social Care adopts a thematic approach to health and social care partnerships. The book offers workable information on key topics such as integrated service models, partnership working and finance, self-management and the co-ordination of services, individual budgets, managing integration and working across the health and social care boundary. The importance of inter-professional practice is emphasised throughout with a key chapter that explores the knowledge, attitudes and skills required by practitioners from different professional backgrounds in order to work together collaboratively. With chapters by leading international commentators, the book explores key terms and approaches to partnership working, helping readers to consider which way of working may be appropriate for which types of outcomes.

Recognize, understand, and manage sleep dysfunction in your patients Sleep disorders can cause neurological problems. Neurological problems can cause sleep disorders. Whatever the cause or effect, neurologists need to be well versed in sleep medicine. This enables effective discussion of sleep problems and improved patient outcomes and satisfaction. Sleep Medicine in Neurology introduces the practicing neurologist to sleep medicine, from examination of the patient to treatment of many sleep disorders. With a focused, practical approach throughout, the expert author team covers: History, examination and sleep testing of the patient Insomnia Excessive daytime sleepiness Narcolepsy Obstructive and central sleep apnea Movement disorders in sleep Parasomnias Sleep disorders in children Clinical in approach, practical in execution, Sleep Medicine in Neurology helps you diagnose and treat your sleep-disordered patients more effectively.

This book provides a practical guide to analysis of simple and complex method comparison data, using Stata, SAS and R. It takes the classical Limits of Agreement as a starting point, and presents it in a proper statistical framework. The model serves as a reference for reporting sources of variation and for providing conversion equations and plots between methods for practical use, including prediction uncertainty. Presents a modeling framework for analysis of data and reporting of results from comparing measurements from different clinical centers and/or different methods. Provides the practical tools for analyzing method comparison studies along with guidance on what to report and how to plan comparison studies and advice on appropriate software. Illustrated throughout with computer examples in R. Supported by a supplementary website hosting an R-package that performs the major part of the analyses needed in the area. Examples in SAS and Stata for the most common situations are also provided. Written by an acknowledged expert on the subject, with a long standing experience as a biostatistician in a clinical environment and a track record of delivering training on the subject. Biostatisticians, clinicians, medical researchers and practitioners involved in research and analysis of measurement methods and laboratory investigations will benefit from this book. Students of statistics, biostatistics, and the chemical sciences will also find this book useful.

Bioinformatics Software Engineering: Delivering Effective Applications will be useful to anyone who wants to understand how successful software can be developed in a rapidly changing environment. A handbook, not a textbook, it is not tied to any particular operating system, platform, language, or methodology. Instead it focuses on principles and practices that have been proven in the real world. It is pragmatic, emphasizing the importance of what the author calls Adaptive Programming – doing what works in your situation, and it is concise, covering the whole software development lifecycle in one slim volume. At each stage, it describes common pitfalls, explains how these can be avoided, and suggests simple techniques which make it easier to deliver better solutions. «Well thought-out … addresses many of the key issues facing developers of bioinformatics software.» (Simon Dear, Director, UK Technology and Development, Bioinformatics Engineering and Integration, Genetics Research, GlaxoSmithKline) Here are some examples from the book itself. On software development: “Writing software properly involves talking to people – often lots of people – and plenty of non-coding work on your part. It requires the ability to dream up new solutions to problems so complicated that they are hard to describe.” From description to specification: “Look for verbs – action words, such as ‘does’, ‘is’ and ‘views’. Identify nouns – naming words, like ‘user’, ‘home’ and ‘sequence’. List the adjectives – describing words, for example ‘quick’, ‘simple’ or ‘precise’. The verbs are the functions that must be provided by your application. The nouns define the parameters to those functions, and the adjectives specify the constraint conditions under which your program must operate.” On how to start writing software: “Handle errors. Take in data. Show output. Get going!” On testing: “It may not be physically possible to test every potential combination of situations that could occur as users interact with a program. But one thing that can be done is to test an application at the agreed extremes of its capability: the maximum number of simultaneous users it has to support, the minimum system configuration it must run on, the lowest communication speed it must cope with, and the most complex operations it must perform. If your program can cope with conditions at the edge of its performance envelope, it is less likely to encounter difficulties in dealing with less challenging situations.” On showing early versions of software to users: “It can be hard explaining the software development process to people who are unfamiliar with it. Code that to you is nearly finished is simply not working to them, and seeing their dream in bits on the workbench can be disappointing to customers, especially when they were expecting to be able to take it for a test drive.” On bugs: “If your users find a genuinely reproducible bug in production code, apologize, fix it fast, and then fix the system that allowed it through. And tell your customers what you are doing, and why, so they will be confident that it will not happen again. Everybody makes mistakes. Don’t make the same ones twice.” And one last thought on successful software development: "You have to be a detective, following up clues and examining evidence to discover what has gone wrong and why. And you have to be a politician, underst

This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature. Provides a guide to statistical methods and application in medical product development Assists readers in undertaking design and analysis of experiments at various stages of product development Features case studies throughout the book, as well as, SAS and R code

This book gives the reader an up-to-date, clear and logical idea of what caring for parkinsonian patients entails – a challenge that clinicians will face for many years to come. It is split into three sections: Section 1: A compilation of the major brain lesions typically seen in PD Section 2: Treatment options in PD Section 3: 25 cases designed to test the reader and the practical application of the information supplied in the other sections.

Now in its second edition, Health Communication: From Theory to Practice provides a comprehensive introduction to theory, intervention design, current issues, and special topics in health communication. The book also represents a hands-on guide to program development, implementation, and evaluation. This second edition further emphasizes the importance of a people-centered and participatory approach to health communication interventions, which takes into account key social determinants of health as well as the interconnection of various health and social fields. While maintaining a strong focus on the importance of behavioral, social, and organizational results as key outcomes of health communication interventions, this second edition also includes new or updated information, theoretical models, resources, and case studies on: Health equity Urban health New media Emergency and risk communication Strategic partnerships in health communication Policy communication and public advocacy Cultural competence Health literacy The evaluation of health communication interventions To access a companion website with instructor resources (PowerPoint presentations for all chapters, sample assignments, and other resources), please visit www.wiley.com/go/schiavo2e This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

Public Health Law Research: Theory and Methods definitively explores the mechanisms, theories and models central to public health law research – a growing field dedicated to measuring and studying law as a central means for advancing public health. Editors Alexander C. Wagenaar and Scott Burris outline integrated theory drawn from numerous disciplines in the social and behavioral sciences; specific mechanisms of legal effect and guidelines for collecting and coding empirical datasets of statutory and case law; optimal research designs for randomized trials and natural experiments for public health law evaluation; and methods for qualitative and cost-benefit studies of law.. They also discuss the challenge of effectively translating the results of scientific evaluations into public health laws and highlight the impact of this growing field. “How exactly the law can best be used as a tool for protecting and enhancing the public’s health has long been the subject of solely opinion and anecdote. Enter Public Health Law Research, a discipline designed to bring the bright light of science to the relationships between law and health. This book is a giant step forward in illuminating that subject.” – Stephen Teret, JD, MPH, Professor, Director, Center for Law and the Public's Health, Johns Hopkins Bloomberg School of Public Health “Wagenaar and Burris bring a dose of much needed rigor to the empirical study of which public health law interventions really matter, and which don’t.” – Bernard S. Black, JD, Chabraja Professor, Northwestern University Law School and Kellogg School of Management Companion Web site: www.josseybass.com/go/wagenaar

This updated second edition of At Risk in America provides a detailed analysis of those key population groups most vulnerable to disease and injury in the United States today-including homeless persons, refugees and immigrants, people living with AIDS, alcohol and substance abusers, high-risk mothers and infants, victims of family or other violence, and the chronically or mentally ill. Lu Ann Aday reviews the major theories and knowledge concerning these at-risk groups and offers new approaches and methodologies for tracing the social determinants and societal influences on health. She examines the specific health needs and risks faced by these groups, their experience in the health care system, the current policies and programs that serve them, and the research and policy initiatives that might be undertaken to help reduce their vulnerability.

In a field saturated with complex and conflicting information, this exciting new book covers information about nutrition before, during and after pregnancy in a clear and user friendly style. The author addresses all the major aspects of the subject, moving from fertility and preparing the body for pregnancy, through to nutrient metabolism, diet and pregnancy outcome, weight gain, special needs, and postpartum changes and nutrition. This guide's evidence based approach will appeal to nutritionists and dietitians, and to many other health professionals who work with women in their childbearing years, including midwives, nurses and family practioners. Each chapter includes a useful set of appendices covering dietary requirements, nutritional composition of key foods and weight gain guidelines, as well as application in practice sections and a summary of key points.

Dietitians need to use advanced communication skills as well as technical expertise in order to assess clients’ needs, identify their problems and help them to manage their diet and lifestyle. The ability to develop a helping relationship is fundamental to achieving a mutually satisfactory dietetic interview. Counselling skills, defined as advanced communication skills used intentionally in a helping relationship, are therefore essential for good dietetic practice at all levels of the profession. This book demonstrates how a practitioner can develop a counselling approach and employ appropriate counselling skills to overcome the communication difficulties encountered by dietitians and those engaged in helping clients change their eating behaviour. New material in the second edition includes an expanded section on the patient interview including assessing motivation and applying aspects of CBT (cognitive behavioural therapy) and a new section on personal development including examples and discussion on issues of interprofessional communication and working in a multidisciplinary team.

Cultural Competence in Health Education and Health Promotion, 2nd edition, examines the importance of ethnic and cultural factors for community health practice. Edited and written by a stellar list of contributors who are experts in field, this book describes essential theories, models, and practices for working with race, ethnicity, gender, and social issues. The authors cover a wide range of topics including demographics, disparities, complementary and alternative medicine, spiritually grounded approaches, multicultural populations, culturally competent needs assessment and planning, communication, workforce, program planning, aging, sexual orientation, and future challenges. This edition has substantially expanded coverage on working with diverse groups, social determinants of health, spirituality, theoretical models for multicultural populations, planning and program evaluation, and aging, with new content includes coverage of disability and health literacy. This edition also reflects the latest standards for Certified Health Education Specialist certification and national standards on Culturally and Linguistically Appropriate Services (CLAS), from Department of Health and Human Services, Office of Minority Health

Designing and Conducting Research in Health and Human Performance shows students how to become effective producers and consumers of health and human performance research. The book provides comprehensive coverage of both quantitative and qualitative research methods and includes step-by-step guidance for writing effective research proposals and theses. In addition, the authors show how to read, assess, interpret, and apply published research and how to conduct basic studies in health, physical education, exercise science, athletic training, and recreation. Designing and Conducting Research in Health and Human Performance is filled with illustrative examples that emphasize the real-world applications of research methods. Throughout, the authors draw on a variety of examples that were selected because they provide a context to further the understanding of health and human performance research. Research to Practice examples and Tips are included by the authors to help students better appreciate the book's content. These study aids provide suggestions and additional resources to assist students in understanding the research process. Key Terms, defined and highlighted, enrich each chapter. Chapter Review Questions, designed to help students comprehend and follow best practices in research methods, close each chapter. Online resources and guides developed by the authors to support and enhance students' learning of important research concepts are available.

Coalitions and Partnerships in Community Health is a step-by-step guide for building durable coalitions to improve community and public health. This important resource provides an in-depth, analytical, and practical approach to building, sustaining, and nurturing these complex organizations. Author Frances Dunn Butterfoss includes all the tools for success in collaborative work from a research and practice-based stance. The book contains useful approaches to the issues, recommendations for action, resources for further study, and examples from actual coalition work. Coalitions and Partnerships in Community Health explores Historical foundations of coalitions and partnerships Principles of collaboration and partnering Benefits and challenges of a coalition approach Coalition frameworks and models Cultivating coalition leadership Roles and responsibilities of coalition staff, leaders, and members Communication, decision-making, and problem-solving methods Vision, mission, and bylaws Effective marketing Planning for sustainability Approaches to assessment Developing strategic and action plans Implementing coalition strategies in the community Media advocacy, strategies, and tips Participatory coalition evaluation

Evidence-based practice is an idea whose time has come. Few concepts can have achieved the status of unchallengeable common sense in such a short space of time, and across such a broad range of professional activity. As yet there have been few opportunities to take stock and reflect on the evidence for evidence-based practice, or the implications of its adoption. How effective or feasible is it in medicine? Is it really different? What are the consequences of not basing practice on research? Can evidence-based practice be used in non-clinical settings, where practitioners must deal with the complexity of multi-problem individuals, families and organizations? This text introduces the key concept of Evidence-Based Practice and accounts for its emergence and rapid expansion within and beyond medicine. It then goes on to describe how evidence-based practice is being translated in key areas (medicine, nursing, mental health education and social welfare) while critically appraising the strengths and weaknesses of evidence-based practice as it applies in a range of fields of professional practice.

The focus of this book is on speech production and speech processing associated with cleft palate, covering phonetic (perceptual and instrumental), phonological and psycholinguistic perspectives, and including coverage of implications for literacy and education, as well as cross-linguistic differences. It draws together a group of international experts in the fields of cleft lip and palate and speech science to provide an up-to-date and in-depth account of the nature of speech production, and the processes and current evidence base of assessment and intervention for speech associated with cleft palate. The consequences of speech disorders associated with cleft on intelligibility and communicative participation are also covered. This book will provide a solid theoretical foundation and a valuable clinical resource for students of speech-language pathology, for practising speech-language pathologists, and for others interested in speech production in cleft palate, including researchers and members of multi-disciplinary cleft teams who wish to know more about the nature of speech difficulties associated with a cleft palate.

With approximately 1 in 6 adults likely to experience a significant mental health problem at any one time (Office for National Statistics), research into effective interventions has never been more important. During the past decade there has been an increasing interest in the role that sport and physical activity can play in the treatment of mental health problems, and in mental health promotion. The benefits resulting from physiological changes during exercise are well documented, including improvement in mood and control of anxiety and depression. Research also suggests that socio-cultural and psychological changes arising from engagement in sport and physical activity carry valuable mental health benefits. Sport and Physical Activity for Mental Health is an evidence-based practical guide for nurses, allied health professionals, social workers, physical activity leaders, and sport coaches. The authors provide comprehensive analysis of a broad range of client narratives, integrating theory and the latest research to explore the effectiveness of various interventions. The book offers readers detailed recommendations, suggestions, and ideas as to how sport and physical activity opportunities can be tailored to provide the greatest mental health benefits.

'I can enthusiastically recommend the Manual of Clinical Paramedic Procedures as the book that I wish had been available to me when I was studying to become a paramedic.' From the foreword by Professor Malcolm Woollard, Chair, College of Paramedics; Professor in Pre-hospital and Emergency Care & Director, Pre-hospital, Emergency & Cardiovascular Care Applied Research Group, Coventry University Clinical procedures are a fundamental aspect of care for practitioners working in pre-hospital settings. The Manual of Clinical Paramedic Procedures is written specifically to support the practice of paramedics, ambulance technicians, first responders and volunteer ambulance personnel. It presents up-to-date, evidence-based expert knowledge, enabling paramedics to deliver effective, patient-focused care. This accessible handbook provides a comprehensive exploration of core competencies and skills, looking at topics including Aseptic Technique, Airway Management, Assisted Ventilation, Cardiopulmonary Resuscitation, Defibrillation and External Cardiac Pacing, Observations, Pain Assessment & Management, Respiratory Therapy, Spinal Management and Venepuncture. Each chapter provides the relevant anatomy & physiology, evidence-based rationales for each procedure, and contraindications of use. Key features: The first UK text to explore clinical procedures for paramedics With further reading and illustrations throughout All procedures include the rationale for the action recommended Guides paramedics in the clinical application of evidence-based procedures