Phase Lock Loops and Frequency Synthesis

The latest frequency synthesis techniques, including sigma-delta, Diophantine, and all-digital Sigma-delta is a frequency synthesis technique that has risen in popularity over the past decade due to its intensely digital nature and its ability to promote miniaturization. A continuation of the popular Frequency Synthesis by Phase Lock, Second Edition, this timely resource provides a broad introduction to sigma-delta by pairing practical simulation results with cutting-edge research. Advanced Frequency Synthesis by Phase Lock discusses both sigma-delta and fractional-n—the still-in-use forerunner to sigma-delta—employing Simulink® models and detailed simulations of results to promote a deeper understanding. After a brief introduction, the book shows how spurs are produced at the synthesizer output by the basic process and different methods for overcoming them. It investigates how various defects in sigma-delta synthesis contribute to spurs or noise in the synthesized signal. Synthesizer configurations are analyzed, and it is revealed how to trade off the various noise sources by choosing loop parameters. Other sigma-delta synthesis architectures are then reviewed. The Simulink simulation models that provided data for the preceding discussions are described, providing guidance in making use of such models for further exploration. Next, another method for achieving wide loop bandwidth simultaneously with fine resolution—the Diophantine Frequency Synthesizer—is introduced. Operation at extreme bandwidths is also covered, further describing the analysis of synthesizers that push their bandwidths close to the sampling-frequency limit. Lastly, the book reviews a newly important technology that is poised to become widely used in high-production consumer electronics—all-digital frequency synthesis. Detailed appendices provide in-depth discussion on various stages of development, and many related resources are available for download, including Simulink models, MATLAB® scripts, spreadsheets, and executable programs. All these features make this authoritative reference ideal for electrical engineers who want to achieve an understanding of sigma-delta frequency synthesis and an awareness of the latest developments in the field.

How to acquire the input frequency from an unlocked state A phase locked loop (PLL) by itself cannot become useful until it has acquired the applied signal's frequency. Often, a PLL will never reach frequency acquisition (capture) without explicit assistive circuits. Curiously, few books on PLLs treat the topic of frequency acquisition in any depth or detail. Frequency Acquisition Techniques for Phase Locked Loops offers a no-nonsense treatment that is equally useful for engineers, technicians, and managers. Since mathematical rigor for its own sake can degenerate into intellectual «rigor mortis,» the author introduces readers to the basics and delivers useful information with clear language and minimal mathematics. With most of the approaches having been developed through years of experience, this completely practical guide explores methods for achieving the locked state in a variety of conditions as it examines: Performance limitations of phase/frequency detector–based phase locked loops The quadricorrelator method for both continuous and sampled modes Sawtooth ramp-and-sample phase detector and how its waveform contains frequency error information that can be extracted The benefits of a self-sweeping, self-extinguishing topology Sweep methods using quadrature mixer-based lock detection The use of digital implementations versus analog Frequency Acquisition Techniques for Phase Locked Loops is an important resource for RF/microwave engineers, in particular, circuit designers; practicing electronics engineers involved in frequency synthesis, phase locked loops, carrier or clock recovery loops, radio-frequency integrated circuit design, and aerospace electronics; and managers wanting to understand the technology of phase locked loops and frequency acquisition assistance techniques or jitter attenuating loops. Errata can be found by visiting the Book Support Site at: http://booksupport.wiley.com

Introducing a new, pioneering approach to integrated circuit design Nanometer Frequency Synthesis Beyond Phase-Locked Loop introduces an innovative new way of looking at frequency that promises to open new frontiers in modern integrated circuit (IC) design. While most books on frequency synthesis deal with the phase-locked loop (PLL), this book focuses on the clock signal. It revisits the concept of frequency, solves longstanding problems in on-chip clock generation, and presents a new time-based information processing approach for future chip design. Beginning with the basics, the book explains how clock signal is used in electronic applications and outlines the shortcomings of conventional frequency synthesis techniques for dealing with clock generation problems. It introduces the breakthrough concept of Time-Average-Frequency, presents the Flying-Adder circuit architecture for the implementation of this approach, and reveals a new circuit device, the Digital-to-Frequency Converter (DFC). Lastly, it builds upon these three key components to explain the use of time rather than level to represent information in signal processing. Provocative, inspiring, and chock-full of ideas for future innovations, the book features: A new way of thinking about the fundamental concept of clock frequency A new circuit architecture for frequency synthesis: the Flying-Adder direct period synthesis A new electronic component: the Digital-to-Frequency Converter A new information processing approach: time-based vs. level-based Examples demonstrating the power of this technology to build better, cheaper, and faster systems Written with the intent of showing readers how to think outside the box, Nanometer Frequency Synthesis Beyond the Phase-Locked Loop is a must-have resource for IC design engineers and researchers as well as anyone who would like to be at the forefront of modern circuit design.

A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and technologies The last decade has seen a rapid expansion in combinatorial technologies, a field where chemistry disciplines intersect with automation, statistics, and information science, as well as certain biological disciplines. Reflecting these multidisciplinary trends, this new work provides a comprehensive overview of the most important aspects of solid-phase synthesis (SPS), combinatorial chemistry, and related combinatorial technologies. It clearly demonstrates how SPS and combinatorial chemistry have extended their application from the pharmaceutical arena to new areas, including biotechnology, material sciences, catalysis, and agrochemical industries, and explores in detail strategies for planning, designing, preparing, and testing of combinatorial libraries in various disciplines. Designed to meet the needs of both experienced combinatorial chemists and newcomers to the field, Solid-Phase Synthesis and Combinatorial Technologies: Surveys the most recent developments in SPS and combinatorial chemistry Explains the entire process, from determining the need for a library to the details necessary for synthesis of the library Discusses choice of format, size, and the rationale behind the design of each synthetic step Surveys the analytical techniques and the purification methods used to characterize and purify combinatorial libraries Employs a large number of examples to illustrate important concepts Includes problems geared toward applying acquired knowledge and designing the steps to SPS/library synthesis Describes the quality control and activity screening of combinatorial libraries for various applications Features a detailed bibliography of more than 1,700 relevant sources

Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesis With its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers everything needed to conduct their own state-of-the-art science experiments. Featuring chapters written by leading researchers in the field, Solid-Phase Organic Synthesis is divided into two parts: Part One, Concepts and Strategies, discusses the linker groups used to attach the synthesis substrate to the solid support, colorimetric tests to identify the presence of functional groups, combinatorial synthesis, and diversity-oriented synthesis. Readers will discover how solid-phase synthesis is currently used to facilitate the discovery of new molecular functionality. The final chapter discusses how using a support can change or increase reaction selectivity. Part Two, Applications, presents examples of the solid-phase synthesis of various classes of organic molecules. Chapters explore general asymmetric synthesis on a support, strategies for heterocyclic synthesis, and synthesis of radioactive organic molecules, dyes, dendrimers, and oligosaccharides. Each chapter ends with a set of conclusions that underscore the key concepts and methods. References in each chapter enable readers to investigate any topic in greater depth. With its presentation of basic concepts as well as recent findings and applications, Solid-Phase Organic Synthesis is the ideal starting point for students and researchers in organic, medicinal, and combinatorial chemistry who want to take full advantage of current solid-phase synthesis techniques.

Solid-Phase Organic Synthesis Edited by Kevin Burgess, Texas A & M University Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling transformation of solution-phase methods to a solid support, while others report major innovations. Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include: Syntheses of guanidines Palladium-catalyzed C-C bond forming reactions S_nAr reactions for the formation of heterocycles Sequence-specific arylalkyne oligomers Resin-supported capture agents and other reagents Synthesis on pins Monitoring of supported reactions using IR Solid-phase syntheses of natural product derivatives Of related interest: Combinatorial Chemistry and Molecular Diversity in Drug Discovery, Eric M. Gordon and James F. Kerwin 1998 (0-471-15518-7) 544 pp. Combinatorial Chemistry Synthesis and Application, Stephen R. Wilson and Anthony W. Czarnik 1997 (0-471-12687-X) 288 pp.

The first overview of this topic begins with some historical aspects and a survey of the principles of the gas aggregation method. The second part covers modifications of this method resulting in different specialized techniques, while the third discusses the post-growth treatment that can be applied to the nanoparticles. The whole is rounded off by a review of future perspectives and the challenges facing the scientific and industrial communities. An excellent resource for anyone working with the synthesis of nanoparticles, both in academia and industry.

Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been developed and are now routinely employed in solid-phase synthesis. Linker Strategies in Solid-Phase Organic Synthesis guides the reader through the evolution of linker units from their genesis in solid-supported peptide chemistry to the cutting edge diversity linker units that are defining a new era of solid phase synthesis. Individual linker classes are covered in easy to follow chapters written by international experts in their respective fields and offer a comprehensive guide to linker technology whilst simultaneously serving as a handbook of synthetic transformations now possible on solid supports. Topics include: the principles of solid phase organic synthesis electrophile and nucleophile cleavable linker units cyclative cleavage as a solid phase strategy photocleavable linker units safety-catch linker units enzyme cleavable linker units T1 and T2 –versatile triazene linker groups hydrazone linker units benzotriazole linker units phosphorus linker units sulfur linker units selenium and tellurium linker units sulfur, oxygen and selenium linker units cleaved by radical processes silicon and germanium linker units boron and stannane linker units bismuth linker units transition metal carbonyl linker units linkers releasing olefins or cycloolefins by ring-closing metathesis fluorous linker units solid-phase radiochemistry The book concludes with extensive linker selection tables, cataloguing the linker units described in this book according to the substrate liberated upon cleavage and conditions used to achieve such cleavage, enabling readers to choose the right linker unit for their synthesis. Linker Strategies in Solid-Phase Organic Synthesis is an essential guide to the diversity of linker units for organic chemists in academia and industry working in the broad areas of solid-phase organic synthesis and diversity oriented synthesis, medicinal chemists in the pharmaceutical industry who routinely employ solid-phase chemistry in the drug discovery business, and advanced undergraduates, postgraduates, and organic chemists with an interest in leading-edge developments in their field.

Broad-based and hands-on, Phase-Lock Basics, Second Edition is both easy to understand and easy to customize. The text can be used as a theoretical introduction for graduate students or, when used with MATLAB simulation software, the book becomes a virtual laboratory for working professionals who want to improve their understanding of the design process and apply it to the demands of specific situations. This second edition features a large body of new statistical data obtained from simulations and uses available experimental data for confirmation of the simulation results.

An in-depth look at the theory and applications of frequency stability An understanding of the acquisition of stable frequency is essential for anyone who needs to solve noise problems in wireless communications. This book offers a thorough introduction to the principles and applications of frequency stability, arming practicing engineers with the tools they need to minimize noise in systems and devices that affect everyday communications for millions of people. With an emphasis on both practical and scientific points of view, Frequency Stability: Introduction and Applications examines frequency and time fluctuations in resonators, as well as the stability of both standard and practical microwave oscillators. It explains noise properties of building circuit blocks, introducing time domain properties and how they relate to noise spectral densities. Including a special chapter devoted to the design and properties of phase locked loops—a crucial topic for frequency synthesizers—the book also: Examines in detail L/F noise, showing how power losses in the propagation material extend over a long period of time Covers sapphire, optoelectronics, MW, and ring oscillators with the discussion of noise in delay-line oscillators with lasers Offers an extended treatment of phase noise in semiconductors and amplifiers based on Van der Ziel investigations Emphasizes the modified Allan variance in the time domain, including exact computations Outlines the relationship between resonator frequency and output phase noises via the feedback theory Featuring numerous tables with actual data, Frequency Stability: Introduction and Applications is an invaluable guide for engineers wishing to rein in acoustic and electromagnetic interference in modern communications.