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Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: «… very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas.» BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.

Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aims to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. “Paradigms of Combinatorial Optimization” is divided in two parts: • Paradigmatic Problems, that handles several famous combinatorial optimization problems as max cut, min coloring, optimal satisfiability tsp, etc., the study of which has largely contributed to both the development, the legitimization and the establishment of the Combinatorial Optimization as one of the most active actual scientific domains; • Classical and New Approaches, that presents the several methodological approaches that fertilize and are fertilized by Combinatorial optimization such as: Polynomial Approximation, Online Computation, Robustness, etc., and, more recently, Algorithmic Game Theory.

Combinatorial optimization is a multidisciplinary scientific area, lying in the interface of three major scientific domains: mathematics, theoretical computer science and management. The three volumes of the Combinatorial Optimization series aim to cover a wide range of topics in this area. These topics also deal with fundamental notions and approaches as with several classical applications of combinatorial optimization. Concepts of Combinatorial Optimization, is divided into three parts: – On the complexity of combinatorial optimization problems, presenting basics about worst-case and randomized complexity; – Classical solution methods, presenting the two most-known methods for solving hard combinatorial optimization problems, that are Branch-and-Bound and Dynamic Programming; – Elements from mathematical programming, presenting fundamentals from mathematical programming based methods that are in the heart of Operations Research since the origins of this field.

The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. «. . . the wealth of material on statistics concerning the multivariate normal distribution is quite exceptional. As such it is a very useful source of information for the general statistician and a must for anyone wanting to penetrate deeper into the multivariate field.» -Mededelingen van het Wiskundig Genootschap «This book is a comprehensive and clearly written text on multivariate analysis from a theoretical point of view.» -The Statistician Aspects of Multivariate Statistical Theory presents a classical mathematical treatment of the techniques, distributions, and inferences based on multivariate normal distribution. Noncentral distribution theory, decision theoretic estimation of the parameters of a multivariate normal distribution, and the uses of spherical and elliptical distributions in multivariate analysis are introduced. Advances in multivariate analysis are discussed, including decision theory and robustness. The book also includes tables of percentage points of many of the standard likelihood statistics used in multivariate statistical procedures. This definitive resource provides in-depth discussion of the multivariate field and serves admirably as both a textbook and reference.

Explains how Hilbert space techniques cross the boundaries into the foundations of probability and statistics. Focuses on the theory of martingales stochastic integration, interpolation and density estimation. Includes a copious amount of problems and examples.

Relevant, concrete, and thorough–the essential data-based text on statistical inference The ability to formulate abstract concepts and draw conclusions from data is fundamental to mastering statistics. Aspects of Statistical Inference equips advanced undergraduate and graduate students with a comprehensive grounding in statistical inference, including nonstandard topics such as robustness, randomization, and finite population inference. A. H. Welsh goes beyond the standard texts and expertly synthesizes broad, critical theory with concrete data and relevant topics. The text follows a historical framework, uses real-data sets and statistical graphics, and treats multiparameter problems, yet is ultimately about the concepts themselves. Written with clarity and depth, Aspects of Statistical Inference: * Provides a theoretical and historical grounding in statistical inference that considers Bayesian, fiducial, likelihood, and frequentist approaches * Illustrates methods with real-data sets on diabetic retinopathy, the pharmacological effects of caffeine, stellar velocity, and industrial experiments * Considers multiparameter problems * Develops large sample approximations and shows how to use them * Presents the philosophy and application of robustness theory * Highlights the central role of randomization in statistics * Uses simple proofs to illuminate foundational concepts * Contains an appendix of useful facts concerning expansions, matrices, integrals, and distribution theory Here is the ultimate data-based text for comparing and presenting the latest approaches to statistical inference.

Learn rigorous statistical methods to ensure valid clinical trials This Second Edition of the critically hailed Clinical Trials builds on the text's reputation as a straightforward and authoritative presentation of statistical methods for clinical trials. Readers are introduced to the fundamentals of design for various types of clinical trials and then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides commonsense solutions. The author bases the revisions and updates on his own classroom experience, as well as feedback from students, instructors, and medical and statistical professionals involved in clinical trials. The Second Edition greatly expands its coverage, ranging from statistical principles to controversial topics, including alternative medicine and ethics. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First Edition will discover completely new chapters, including: * Contexts for clinical trials * Statistical perspectives * Translational clinical trials * Dose-finding and dose-ranging designs Each chapter is accompanied by a summary to reinforce the key points. Revised discussion questions stimulate critical thinking and help readers understand how they can apply their newfound knowledge, and updated references are provided to direct readers to the most recent literature. This text distinguishes itself with its accessible and broad coverage of statistical design methods–the crucial building blocks of clinical trials and medical research. Readers learn to conduct clinical trials that produce valid qualitative results backed by rigorous statistical methods.

The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. «[A]nyone who works with Markov processes whose state space is uncountably infinite will need this most impressive book as a guide and reference.» -American Scientist «There is no question but that space should immediately be reserved for [this] book on the library shelf. Those who aspire to mastery of the contents should also reserve a large number of long winter evenings.» -Zentralblatt f?r Mathematik und ihre Grenzgebiete/Mathematics Abstracts «Ethier and Kurtz have produced an excellent treatment of the modern theory of Markov processes that [is] useful both as a reference work and as a graduate textbook.» -Journal of Statistical Physics Markov Processes presents several different approaches to proving weak approximation theorems for Markov processes, emphasizing the interplay of methods of characterization and approximation. Martingale problems for general Markov processes are systematically developed for the first time in book form. Useful to the professional as a reference and suitable for the graduate student as a text, this volume features a table of the interdependencies among the theorems, an extensive bibliography, and end-of-chapter problems.

The first comprehensive survey of mathematics' most fascinating number sequences Fibonacci and Lucas numbers have intrigued amateur and professional mathematicians for centuries. This volume represents the first attempt to compile a definitive history and authoritative analysis of these famous integer sequences, complete with a wealth of exciting applications, enlightening examples, and fun exercises that offer numerous opportunities for exploration and experimentation. The author has assembled a myriad of fascinating properties of both Fibonacci and Lucas numbers-as developed by a wide range of sources-and catalogued their applications in a multitude of widely varied disciplines such as art, stock market investing, engineering, and neurophysiology. Most of the engaging and delightful material here is easily accessible to college and even high school students, though advanced material is included to challenge more sophisticated Fibonacci enthusiasts. A historical survey of the development of Fibonacci and Lucas numbers, biographical sketches of intriguing personalities involved in developing the subject, and illustrative examples round out this thorough and amusing survey. Most chapters conclude with numeric and theoretical exercises that do not rely on long and tedious proofs of theorems. Highlights include: * Balanced blend of theory and real-world applications * Excellent reference material for student reports and projects * User-friendly, informal, and entertaining writing style * Historical interjections and short biographies that add a richer perspective to the topic * Reference sections providing important symbols, problem solutions, and fundamental properties from the theory of numbers and matrices Fibonacci and Lucas Numbers with Applications provides mathematicians with a wealth of reference material in one convenient volume and presents an in-depth and entertaining resource for enthusiasts at every level and from any background.

A thorough review of the most current regression methods in time series analysis Regression methods have been an integral part of time series analysis for over a century. Recently, new developments have made major strides in such areas as non-continuous data where a linear model is not appropriate. This book introduces the reader to newer developments and more diverse regression models and methods for time series analysis. Accessible to anyone who is familiar with the basic modern concepts of statistical inference, Regression Models for Time Series Analysis provides a much-needed examination of recent statistical developments. Primary among them is the important class of models known as generalized linear models (GLM) which provides, under some conditions, a unified regression theory suitable for continuous, categorical, and count data. The authors extend GLM methodology systematically to time series where the primary and covariate data are both random and stochastically dependent. They introduce readers to various regression models developed during the last thirty years or so and summarize classical and more recent results concerning state space models. To conclude, they present a Bayesian approach to prediction and interpolation in spatial data adapted to time series that may be short and/or observed irregularly. Real data applications and further results are presented throughout by means of chapter problems and complements. Notably, the book covers: * Important recent developments in Kalman filtering, dynamic GLMs, and state-space modeling * Associated computational issues such as Markov chain, Monte Carlo, and the EM-algorithm * Prediction and interpolation * Stationary processes

The emergence of social networks, OpenCourseWare, Massive Open Online Courses, informal remote learning and connectivist approaches to learning has made the analysis and evaluation of Digital Learning Environments more complex. Modeling these complex systems makes it possible to transcribe the phenomena observed and facilitates the study of these processes with the aid of specific tools. Once this essential step is taken, it then becomes possible to develop plausible scenarios from the observation of emerging phenomena and dominant trends. This book highlights the contribution of complex systems theory in the study of next generation Digital Learning Environments. It describes a realistic approach and proposes a range of effective management tools to achieve it.

Designed as an introduction to statistical distribution theory. * Includes a first chapter on basic notations and definitions that are essential to working with distributions. * Remaining chapters are divided into three parts: Discrete Distributions, Continuous Distributions, and Multivariate Distributions. * Exercises are incorporated throughout the text in order to enhance understanding of materials just taught.

A rigorous introduction to calculus in vector spaces The concepts and theorems of advanced calculus combined with related computational methods are essential to understanding nearly all areas of quantitative science. Analysis in Vector Spaces presents the central results of this classic subject through rigorous arguments, discussions, and examples. The book aims to cultivate not only knowledge of the major theoretical results, but also the geometric intuition needed for both mathematical problem-solving and modeling in the formal sciences. The authors begin with an outline of key concepts, terminology, and notation and also provide a basic introduction to set theory, the properties of real numbers, and a review of linear algebra. An elegant approach to eigenvector problems and the spectral theorem sets the stage for later results on volume and integration. Subsequent chapters present the major results of differential and integral calculus of several variables as well as the theory of manifolds. Additional topical coverage includes: Sets and functions Real numbers Vector functions Normed vector spaces First- and higher-order derivatives Diffeomorphisms and manifolds Multiple integrals Integration on manifolds Stokes' theorem Basic point set topology Numerous examples and exercises are provided in each chapter to reinforce new concepts and to illustrate how results can be applied to additional problems. Furthermore, proofs and examples are presented in a clear style that emphasizes the underlying intuitive ideas. Counterexamples are provided throughout the book to warn against possible mistakes, and extensive appendices outline the construction of real numbers, include a fundamental result about dimension, and present general results about determinants. Assuming only a fundamental understanding of linear algebra and single variable calculus, Analysis in Vector Spaces is an excellent book for a second course in analysis for mathematics, physics, computer science, and engineering majors at the undergraduate and graduate levels. It also serves as a valuable reference for further study in any discipline that requires a firm understanding of mathematical techniques and concepts.

Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials. Readers will encounter the principles of design for various types of clinical trials, and are then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides common sense solutions. All stages of therapeutic development are discussed in detail, and the methods are not restricted to a single clinical application area. The authors bases current revisions and updates on his own experience, classroom instruction, and feedback from teachers and medical and statistical professionals involved in clinical trials. The Third Edition greatly expands its coverage, ranging from statistical principles to new and provocative topics, including alternative medicine and ethics, middle development, comparative studies, and adaptive designs. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First and Second Editions will discover revamped exercise sets; an updated and extensive reference section; new material on endpoints and the developmental pipeline, among others; and revisions of numerous sections. In addition, this book: • Features accessible and broad coverage of statistical design methods—the crucial building blocks of clinical trials and medical research – now complete with new chapters on overall development, middle development, comparative studies, and adaptive designs • Teaches readers to design clinical trials that produce valid qualitative results backed by rigorous statistical methods • Contains an introduction and summary in each chapter to reinforce key points • Includes discussion questions to stimulate critical thinking and help readers understand how they can apply their newfound knowledge • Provides extensive references to direct readers to the most recent literature, and there are numerous new or revised exercises throughout the book Clinical Trials: A Methodologic Perspective, Third Edition is a textbook accessible to advanced undergraduate students in the quantitative sciences, graduate students in public health and the life sciences, physicians training in clinical research methods, and biostatisticians and epidemiologists. Steven Piantadosi, MD, PhD, is the Phase One Foundation Distinguished Chair and Director of the Samuel Oschin Cancer Institute, and Professor of Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Piantadosi is one of the world’s leading experts in the design and analysis of clinical trials for cancer research. He has taught clinical trials methods extensively in formal courses and short venues. He has advised numerous academic programs and collaborations nationally regarding clinical trial design and conduct, and has served on external advisory boards for the National Institutes of Health and other prominent cancer programs and centers. The author of more than 260 peer-reviewed scientific articles, Dr. Piantadosi has published extensively on research results, clinical applications, and trial methodology. While his papers have contributed to many areas of oncology, he has also collaborated on diverse studies outside oncology including lung disease and degenerative neurological disease.

This book presents basic stochastic processes, stochastic calculus including L?vy processes on one hand, and Markov and Semi Markov models on the other. From the financial point of view, essential concepts such as the Black and Scholes model, VaR indicators, actuarial evaluation, market values, fair pricing play a central role and will be presented. The authors also present basic concepts so that this series is relatively self-contained for the main audience formed by actuaries and particularly with ERM (enterprise risk management) certificates, insurance risk managers, students in Master in mathematics or economics and people involved in Solvency II for insurance companies and in Basel II and III for banks.

The purpose of this book is to provide a comprehensive discussion of the available results for discrete time branching processes with random control functions. The independence of individuals’ reproduction is a fundamental assumption in the classical branching processes. Alternatively, the controlled branching processes (CBPs) allow the number of reproductive individuals in one generation to decrease or increase depending on the size of the previous generation. Generating a wide range of behaviors, the CBPs have been successfully used as modeling tools in diverse areas of applications.

Credit risk is one of the most important contemporary problems for banks and insurance companies. Indeed, for banks, more than forty percent of the equities are necessary to cover this risk. Though this problem is studied by large rating agencies with substantial economic, social and financial tools, building stochastic models is nevertheless necessary to complete this descriptive orientation. This book presents a complete presentation of such a category of models using homogeneous and non-homogeneous semi-Markov processes developed by the authors in several recent papers. This approach provides a good method of evaluating the default risk and the classical VaR indicators used for Solvency II and Basel III governance rules. This book is the first to present a complete semi-Markov treatment of credit risk while also insisting on the practical use of the models presented here, including numerical aspects, so that this book is not only useful for scientific research but also to managers working in this field for banks, insurance companies, pension funds and other financial institutions.

An accessible and multidisciplinaryintroduction to cellular automata As the applicability of cellular automata broadens and technology advances, there is a need for a concise, yet thorough, resource that lays the foundation of key cellularautomata rules and applications. In recent years, Stephen Wolfram's A New Kind of Science has brought the modeling power that lies in cellular automata to the attentionof the scientific world, and now, Cellular Automata: A Discrete View of the World presents all the depth, analysis, and applicability of the classic Wolfram text in a straightforward, introductory manner. This book offers an introduction to cellular automata as a constructive method for modeling complex systems where patterns of self-organization arising from simple rules are revealed in phenomena that exist across a wide array of subject areas, including mathematics, physics, economics, and the social sciences. The book begins with a preliminary introduction to cellular automata, including a brief history of the topic along with coverage of sub-topics such as randomness, dimension, information, entropy, and fractals. The author then provides a complete discussion of dynamical systems and chaos due to their close connection with cellular automata and includes chapters that focus exclusively on one- and two-dimensional cellular automata. The next and most fascinating area of discussion is the application of these types of cellular automata in order to understand the complex behavior that occurs in natural phenomena. Finally, the continually evolving topic of complexity is discussed with a focus on how to properly define, identify, and marvel at its manifestations in various environments. The author's focus on the most important principles of cellular automata, combined with his ability to present complex material in an easy-to-follow style, makes this book a very approachable and inclusive source for understanding the concepts and applications of cellular automata. The highly visual nature of the subject is accented with over 200 illustrations, including an eight-page color insert, which provide vivid representations of the cellular automata under discussion. Readers also have the opportunity to follow and understand the models depicted throughout the text and create their own cellular automata using Java applets and simple computer code, which are available via the book's FTP site. This book serves as a valuable resource for undergraduate and graduate students in the physical, biological, and social sciences and may also be of interest to any reader with a scientific or basic mathematical background.

Volume II provides an advanced approach to the extended gibonacci family, which includes Fibonacci, Lucas, Pell, Pell-Lucas, Jacobsthal, Jacobsthal-Lucas, Vieta, Vieta-Lucas, and Chebyshev polynomials of both kinds. This volume offers a uniquely unified, extensive, and historical approach that will appeal to both students and professional mathematicians. As in Volume I, Volume II focuses on problem-solving techniques such as pattern recognition; conjecturing; proof-techniques, and applications. It offers a wealth of delightful opportunities to explore and experiment, as well as plentiful material for group discussions, seminars, presentations, and collaboration. In addition, the material covered in this book promotes intellectual curiosity, creativity, and ingenuity. Volume II features: A wealth of examples, applications, and exercises of varying degrees of difficulty and sophistication. Numerous combinatorial and graph-theoretic proofs and techniques. A uniquely thorough discussion of gibonacci subfamilies, and the fascinating relationships that link them. Examples of the beauty, power, and ubiquity of the extended gibonacci family. An introduction to tribonacci polynomials and numbers, and their combinatorial and graph-theoretic models. Abbreviated solutions provided for all odd-numbered exercises. Extensive references for further study. This volume will be a valuable resource for upper-level undergraduates and graduate students, as well as for independent study projects, undergraduate and graduate theses. It is the most comprehensive work available, a welcome addition for gibonacci enthusiasts in computer science, electrical engineering, and physics, as well as for creative and curious amateurs.

A self-contained, contemporary treatment of the analysis of long-range dependent data Long-Memory Time Series: Theory and Methods provides an overview of the theory and methods developed to deal with long-range dependent data and describes the applications of these methodologies to real-life time series. Systematically organized, it begins with the foundational essentials, proceeds to the analysis of methodological aspects (Estimation Methods, Asymptotic Theory, Heteroskedastic Models, Transformations, Bayesian Methods, and Prediction), and then extends these techniques to more complex data structures. To facilitate understanding, the book: Assumes a basic knowledge of calculus and linear algebra and explains the more advanced statistical and mathematical concepts Features numerous examples that accelerate understanding and illustrate various consequences of the theoretical results Proves all theoretical results (theorems, lemmas, corollaries, etc.) or refers readers to resources with further demonstration Includes detailed analyses of computational aspects related to the implementation of the methodologies described, including algorithm efficiency, arithmetic complexity, CPU times, and more Includes proposed problems at the end of each chapter to help readers solidify their understanding and practice their skills A valuable real-world reference for researchers and practitioners in time series analysis, economerics, finance, and related fields, this book is also excellent for a beginning graduate-level course in long-memory processes or as a supplemental textbook for those studying advanced statistics, mathematics, economics, finance, engineering, or physics. A companion Web site is available for readers to access the S-Plus and R data sets used within the text.

This new edition brings the fascinating and intriguing history of mathematics to life The Second Edition of this internationally acclaimed text has been thoroughly revised, updated, and reorganized to give readers a fresh perspective on the evolution of mathematics. Written by one of the world's leading experts on the history of mathematics, the book details the key historical developments in the field, providing an understanding and appreciation of how mathematics influences today's science, art, music, literature, and society. In the first edition, each chapter was devoted to a single culture. This Second Edition is organized by subject matter: a general survey of mathematics in many cultures, arithmetic, geometry, algebra, analysis, and mathematical inference. This new organization enables students to focus on one complete topic and, at the same time, compare how different cultures approached each topic. Many new photographs and diagrams have been added to this edition to enhance the presentation. The text is divided into seven parts: The World of Mathematics and the Mathematics of the World, including the origin and prehistory of mathematics, cultural surveys, and women mathematicians Numbers, including counting, calculation, ancient number theory, and numbers and number theory in modern mathematics Color Plates, illustrating the impact of mathematics on civilizations from Egypt to Japan to Mexico to modern Europe Space, including measurement, Euclidean geometry, post-Euclidean geometry, and modern geometrics Algebra, including problems leading to algebra, equations and methods, and modern algebra Analysis, including the calculus, real, and complex analysis Mathematical Inference, including probability and statistics, and logic and set theory As readers progress through the text, they learn about the evolution of each topic, how different cultures devised their own solutions, and how these solutions enabled the cultures to develop and progress. In addition, readers will meet some of the greatest mathematicians of the ages, who helped lay the groundwork for today's science and technology. The book's lively approach makes it appropriate for anyone interested in learning how the field of mathematics came to be what it is today. It can also serve as a textbook for undergraduate or graduate-level courses. An Instructor's Manual presenting detailed solutions to all the problems in the book is available upon request from the Wiley editorial department.

A comprehensive and accessible guide to panel data analysis using EViews software This book explores the use of EViews software in creating panel data analysis using appropriate empirical models and real datasets. Guidance is given on developing alternative descriptive statistical summaries for evaluation and providing policy analysis based on pool panel data. Various alternative models based on panel data are explored, including univariate general linear models, fixed effect models and causal models, and guidance on the advantages and disadvantages of each one is given. Panel Data Analysis using EViews: Provides step-by-step guidance on how to apply EViews software to panel data analysis using appropriate empirical models and real datasets. Examines a variety of panel data models along with the author’s own empirical findings, demonstrating the advantages and limitations of each model. Presents growth models, time-related effects models, and polynomial models, in addition to the models which are commonly applied for panel data. Includes more than 250 examples divided into three groups of models (stacked, unstacked, and structured panel data), together with notes and comments. Provides guidance on which models not to use in a given scenario, along with advice on viable alternatives. Explores recent new developments in panel data analysis An essential tool for advanced undergraduate or graduate students and applied researchers in finance, econometrics and population studies. Statisticians and data analysts involved with data collected over long time periods will also find this book a useful resource.

Praise for the Second Edition «An amazing assemblage of worldwide contributions in mathematics and, in addition to use as a course book, a valuable resource . . . essential.» —CHOICE This Third Edition of The History of Mathematics examines the elementary arithmetic, geometry, and algebra of numerous cultures, tracing their usage from Mesopotamia, Egypt, Greece, India, China, and Japan all the way to Europe during the Medieval and Renaissance periods where calculus was developed. Aimed primarily at undergraduate students studying the history of mathematics for science, engineering, and secondary education, the book focuses on three main ideas: the facts of who, what, when, and where major advances in mathematics took place; the type of mathematics involved at the time; and the integration of this information into a coherent picture of the development of mathematics. In addition, the book features carefully designed problems that guide readers to a fuller understanding of the relevant mathematics and its social and historical context. Chapter-end exercises, numerous photographs, and a listing of related websites are also included for readers who wish to pursue a specialized topic in more depth. Additional features of The History of Mathematics, Third Edition include: Material arranged in a chronological and cultural context Specific parts of the history of mathematics presented as individual lessons New and revised exercises ranging between technical, factual, and integrative Individual PowerPoint presentations for each chapter and a bank of homework and test questions (in addition to the exercises in the book) An emphasis on geography, culture, and mathematics In addition to being an ideal coursebook for undergraduate students, the book also serves as a fascinating reference for mathematically inclined individuals who are interested in learning about the history of mathematics.

Presents a uniquely balanced approach that bridges introductory and advanced topics in modern mathematics An accessible treatment of the fundamentals of modern mathematics, Principles of Mathematics: A Primer provides a unique approach to introductory andadvanced mathematical topics. The book features six main subjects, whichcan be studied independently or in conjunction with each other including: settheory; mathematical logic; proof theory; group theory; theory of functions; andlinear algebra. The author begins with comprehensive coverage of the necessary building blocks in mathematics and emphasizes the need to think abstractly and develop an appreciation for mathematical thinking. Maintaining a useful balance of introductory coverage and mathematical rigor, Principles of Mathematics: A Primer features: Detailed explanations of important theorems and their applications Hundreds of completely solved problems throughout each chapter Numerous exercises at the end of each chapter to encourage further exploration Discussions of interesting and provocative issues that spark readers’ curiosity and facilitate a better understanding and appreciation of the field of mathematics Principles of Mathematics: A Primer is an ideal textbook for upper-undergraduate courses in the foundations of mathematics and mathematical logic as well as for graduate-level courses related to physics, engineering, and computer science. The book is also a useful reference for readers interested in pursuing careers in mathematics and the sciences. Vladimir Lepetic, PhD, is Professor in the Department of Mathematical Sciences at DePaul University. His research interests include mathematical physics, set theory, foundations of mathematics, and the philosophy of mathematics.

A comprehensive introduction to the theory and practice of contemporary data science analysis for railway track engineering Featuring a practical introduction to state-of-the-art data analysis for railway track engineering, Big Data and Differential Privacy: Analysis Strategies for Railway Track Engineering addresses common issues with the implementation of big data applications while exploring the limitations, advantages, and disadvantages of more conventional methods. In addition, the book provides a unifying approach to analyzing large volumes of data in railway track engineering using an array of proven methods and software technologies. Dr. Attoh-Okine considers some of today’s most notable applications and implementations and highlights when a particular method or algorithm is most appropriate. Throughout, the book presents numerous real-world examples to illustrate the latest railway engineering big data applications of predictive analytics, such as the Union Pacific Railroad’s use of big data to reduce train derailments, increase the velocity of shipments, and reduce emissions. In addition to providing an overview of the latest software tools used to analyze the large amount of data obtained by railways, Big Data and Differential Privacy: Analysis Strategies for Railway Track Engineering: • Features a unified framework for handling large volumes of data in railway track engineering using predictive analytics, machine learning, and data mining • Explores issues of big data and differential privacy and discusses the various advantages and disadvantages of more conventional data analysis techniques • Implements big data applications while addressing common issues in railway track maintenance • Explores the advantages and pitfalls of data analysis software such as R and Spark, as well as the Apache™ Hadoop® data collection database and its popular implementation MapReduce Big Data and Differential Privacy is a valuable resource for researchers and professionals in transportation science, railway track engineering, design engineering, operations research, and railway planning and management. The book is also appropriate for graduate courses on data analysis and data mining, transportation science, operations research, and infrastructure management. NII ATTOH-OKINE, PhD, PE is Professor in the Department of Civil and Environmental Engineering at the University of Delaware. The author of over 70 journal articles, his main areas of research include big data and data science; computational intelligence; graphical models and belief functions; civil infrastructure systems; image and signal processing; resilience engineering; and railway track analysis. Dr. Attoh-Okine has edited five books in the areas of computational intelligence, infrastructure systems and has served as an Associate Editor of various ASCE and IEEE journals.

A clear and lucid bottom-up approach to the basic principles of evolutionary algorithms Evolutionary algorithms (EAs) are a type of artificial intelligence. EAs are motivated by optimization processes that we observe in nature, such as natural selection, species migration, bird swarms, human culture, and ant colonies. This book discusses the theory, history, mathematics, and programming of evolutionary optimization algorithms. Featured algorithms include genetic algorithms, genetic programming, ant colony optimization, particle swarm optimization, differential evolution, biogeography-based optimization, and many others. Evolutionary Optimization Algorithms: Provides a straightforward, bottom-up approach that assists the reader in obtaining a clear—but theoretically rigorous—understanding of evolutionary algorithms, with an emphasis on implementation Gives a careful treatment of recently developed EAs—including opposition-based learning, artificial fish swarms, bacterial foraging, and many others— and discusses their similarities and differences from more well-established EAs Includes chapter-end problems plus a solutions manual available online for instructors Offers simple examples that provide the reader with an intuitive understanding of the theory Features source code for the examples available on the author's website Provides advanced mathematical techniques for analyzing EAs, including Markov modeling and dynamic system modeling Evolutionary Optimization Algorithms: Biologically Inspired and Population-Based Approaches to Computer Intelligence is an ideal text for advanced undergraduate students, graduate students, and professionals involved in engineering and computer science.

Praise for the First Edition «. . . outstandingly appealing with regard to its style, contents, considerations of requirements of practice, choice of examples, and exercises.»—Zentralblatt MATH «. . . carefully structured with many detailed worked examples.»—The Mathematical Gazette The Second Edition of the highly regarded An Introduction to Numerical Methods and Analysis provides a fully revised guide to numerical approximation. The book continues to be accessible and expertly guides readers through the many available techniques of numerical methods and analysis. An Introduction to Numerical Methods and Analysis, Second Edition reflects the latest trends in the field, includes new material and revised exercises, and offers a unique emphasis on applications. The author clearly explains how to both construct and evaluate approximations for accuracy and performance, which are key skills in a variety of fields. A wide range of higher-level methods and solutions, including new topics such as the roots of polynomials, spectral collocation, finite element ideas, and Clenshaw-Curtis quadrature, are presented from an introductory perspective, and the Second Edition also features: Chapters and sections that begin with basic, elementary material followed by gradual coverage of more advanced material Exercises ranging from simple hand computations to challenging derivations and minor proofs to programming exercises Widespread exposure and utilization of MATLAB An appendix that contains proofs of various theorems and other material The book is an ideal textbook for students in advanced undergraduate mathematics and engineering courses who are interested in gaining an understanding of numerical methods and numerical analysis.

An introductory course in summability theory for students, researchers, physicists, and engineers In creating this book, the authors’ intent was to provide graduate students, researchers, physicists, and engineers with a reasonable introduction to summability theory. Over the course of nine chapters, the authors cover all of the fundamental concepts and equations informing summability theory and its applications, as well as some of its lesser known aspects. Following a brief introduction to the history of summability theory, general matrix methods are introduced, and the Silverman-Toeplitz theorem on regular matrices is discussed. A variety of special summability methods, including the N?rlund method, the Weighted Mean method, the Abel method, and the (C, 1) – method are next examined. An entire chapter is devoted to a discussion of some elementary Tauberian theorems involving certain summability methods. Following this are chapters devoted to matrix transforms of summability and absolute summability domains of reversible and normal methods; the notion of a perfect matrix method; matrix transforms of summability and absolute summability domains of the Ces?ro and Riesz methods; convergence and the boundedness of sequences with speed; and convergence, boundedness, and summability with speed. • Discusses results on matrix transforms of several matrix methods • The only English-language textbook describing the notions of convergence, boundedness, and summability with speed, as well as their applications in approximation theory • Compares the approximation orders of Fourier expansions in Banach spaces by different matrix methods • Matrix transforms of summability domains of regular perfect matrix methods are examined • Each chapter contains several solved examples and end-of-chapter exercises, including hints for solutions An Introductory Course in Summability Theory is the ideal first text in summability theory for graduate students, especially those having a good grasp of real and complex analysis. It is also a valuable reference for mathematics researchers and for physicists and engineers who work with Fourier series, Fourier transforms, or analytic continuation. ANTS AASMA, PhD, is Associate Professor of Mathematical Economics in the Department of Economics and Finance at Tallinn University of Technology, Estonia. HEMEN DUTTA, PhD, is Senior Assistant Professor of Mathematics at Gauhati University, India. P.N. NATARAJAN, PhD, is Formerly Professor and Head of the Department of Mathematics, Ramakrishna Mission Vivekananda College, Chennai, Tamilnadu, India.

Presents new models, methods, and techniques and considers important real-world applications in political science, sociology, economics, marketing, and finance Emphasizing interdisciplinary coverage, Bayesian Inference in the Social Sciences builds upon the recent growth in Bayesian methodology and examines an array of topics in model formulation, estimation, and applications. The book presents recent and trending developments in a diverse, yet closely integrated, set of research topics within the social sciences and facilitates the transmission of new ideas and methodology across disciplines while maintaining manageability, coherence, and a clear focus. Bayesian Inference in the Social Sciences features innovative methodology and novel applications in addition to new theoretical developments and modeling approaches, including the formulation and analysis of models with partial observability, sample selection, and incomplete data. Additional areas of inquiry include a Bayesian derivation of empirical likelihood and method of moment estimators, and the analysis of treatment effect models with endogeneity. The book emphasizes practical implementation, reviews and extends estimation algorithms, and examines innovative applications in a multitude of fields. Time series techniques and algorithms are discussed for stochastic volatility, dynamic factor, and time-varying parameter models. Additional features include: Real-world applications and case studies that highlight asset pricing under fat-tailed distributions, price indifference modeling and market segmentation, analysis of dynamic networks, ethnic minorities and civil war, school choice effects, and business cycles and macroeconomic performance State-of-the-art computational tools and Markov chain Monte Carlo algorithms with related materials available via the book’s supplemental website Interdisciplinary coverage from well-known international scholars and practitioners Bayesian Inference in the Social Sciences is an ideal reference for researchers in economics, political science, sociology, and business as well as an excellent resource for academic, government, and regulation agencies. The book is also useful for graduate-level courses in applied econometrics, statistics, mathematical modeling and simulation, numerical methods, computational analysis, and the social sciences.

Praise for the Third Edition «. . . guides and leads the reader through the learning path . . . [e]xamples are stated very clearly and the results are presented with attention to detail.» —MAA Reviews Fully updated to reflect new developments in the field, the Fourth Edition of Introduction to Optimization fills the need for accessible treatment of optimization theory and methods with an emphasis on engineering design. Basic definitions and notations are provided in addition to the related fundamental background for linear algebra, geometry, and calculus. This new edition explores the essential topics of unconstrained optimization problems, linear programming problems, and nonlinear constrained optimization. The authors also present an optimization perspective on global search methods and include discussions on genetic algorithms, particle swarm optimization, and the simulated annealing algorithm. Featuring an elementary introduction to artificial neural networks, convex optimization, and multi-objective optimization, the Fourth Edition also offers: A new chapter on integer programming Expanded coverage of one-dimensional methods Updated and expanded sections on linear matrix inequalities Numerous new exercises at the end of each chapter MATLAB exercises and drill problems to reinforce the discussed theory and algorithms Numerous diagrams and figures that complement the written presentation of key concepts MATLAB M-files for implementation of the discussed theory and algorithms (available via the book's website) Introduction to Optimization, Fourth Edition is an ideal textbook for courses on optimization theory and methods. In addition, the book is a useful reference for professionals in mathematics, operations research, electrical engineering, economics, statistics, and business.

Autoregressive Conditional Heteroskedastic (ARCH) processes are used in finance to model asset price volatility over time. This book introduces both the theory and applications of ARCH models and provides the basic theoretical and empirical background, before proceeding to more advanced issues and applications. The Authors provide coverage of the recent developments in ARCH modelling which can be implemented using econometric software, model construction, fitting and forecasting and model evaluation and selection. Key Features: Presents a comprehensive overview of both the theory and the practical applications of ARCH, an increasingly popular financial modelling technique. Assumes no prior knowledge of ARCH models; the basics such as model construction are introduced, before proceeding to more complex applications such as value-at-risk, option pricing and model evaluation. Uses empirical examples to demonstrate how the recent developments in ARCH can be implemented. Provides step-by-step instructive examples, using econometric software, such as Econometric Views and the G@RCH module for the Ox software package, used in Estimating and Forecasting ARCH Models. Accompanied by a CD-ROM containing links to the software as well as the datasets used in the examples. Aimed at readers wishing to gain an aptitude in the applications of financial econometric modelling with a focus on practical implementation, via applications to real data and via examples worked with econometrics packages.

The concise yet authoritative presentation of key techniques for basic mixtures experiments Inspired by the author's bestselling advanced book on the topic, A Primer on Experiments with Mixtures provides an introductory presentation of the key principles behind experimenting with mixtures. Outlining useful techniques through an applied approach with examples from real research situations, the book supplies a comprehensive discussion of how to design and set up basic mixture experiments, then analyze the data and draw inferences from results. Drawing from his extensive experience teaching the topic at various levels, the author presents the mixture experiments in an easy-to-follow manner that is void of unnecessary formulas and theory. Succinct presentations explore key methods and techniques for carrying out basic mixture experiments, including: Designs and models for exploring the entire simplex factor space, with coverage of simplex-lattice and simplex-centroid designs, canonical polynomials, the plotting of individual residuals, and axial designs Multiple constraints on the component proportions in the form of lower and/or upper bounds, introducing L-Pseudocomponents, multicomponent constraints, and multiple lattice designs for major and minor component classifications Techniques for analyzing mixture data such as model reduction and screening components, as well as additional topics such as measuring the leverage of certain design points Models containing ratios of the components, Cox's mixture polynomials, and the fitting of a slack variable model A review of least squares and the analysis of variance for fitting data Each chapter concludes with a summary and appendices with details on the technical aspects of the material. Throughout the book, exercise sets with selected answers allow readers to test their comprehension of the material, and References and Recommended Reading sections outline further resources for study of the presented topics. A Primer on Experiments with Mixtures is an excellent book for one-semester courses on mixture designs and can also serve as a supplement for design of experiments courses at the upper-undergraduate and graduate levels. It is also a suitable reference for practitioners and researchers who have an interest in experiments with mixtures and would like to learn more about the related mixture designs and models.

Presents information sources and methodologies for modeling and simulating banking system stability Combining both academic and institutional knowledge and experience, Banking Systems Simulation: Theory, Practice, and Application of Modeling Shocks, Losses, and Contagion presents banking system risk modeling clearly within a theoretical framework. Written from the global financial perspective, the book explores single bank risk, common bank exposures, and contagion, and how these apply on a systemic level. Zedda approaches these simulation methods logically by providing the basic building blocks of modeling and simulation, and then delving further into the individual techniques that make up a systems model. In addition, the author provides clear and detailed explanations of the foundational research into the mathematical and legal concepts used to analyze banking risk problems, measures and data for representing the main banking risk sources, and the major problems researchers are likely to encounter. There are numerous software descriptions throughout, with references and tools to help readers gain a proper understanding of the presented techniques and possibly develop new applications and research. The book concludes with an appendix that features real-world datasets and models. In addition, this book: • Provides a comprehensive overview of methods for analyzing models and simulating risk for banking and financial systems • Provides a clear presentation of the technical and legal concepts used in banking regulation • Presents unique insights from an expert’s perspective, with specific coverage of assessing risks and developing what-if analyses at the systems level • Concludes with a discussion of applications, including banking systems regulation what-if tests, cost-benefit analysis, evaluations of banking systems stability effects on public finances, dimensioning, and risk-based contributions for Deposit Guarantee Schemes (DGS) and Resolution Funds Banking Systems Simulation: Theory, Practice, and Application of Modeling Shocks, Losses, and Contagion is ideal for banking researchers focusing on computational methods of analysis as well as an appropriate reference for graduate-level students in banking, finance, and computational methods. Stefano Zedda is Researcher in Financial Mathematics at the University of Cagliari in Italy and qualified as associate professor in banking and corporate finance. His research is mainly focused on quantitative analyses for banking and finance, with a particular focus on banking systems modeling and simulation. In 2008, Zedda developed the mathematical modeling and software implementation of the Systemic Model for Banking Originated Losses (SYMBOL), further developed during his activity at the European Commission. The Commission subsequently adopted it as a standard tool for testing banking regulation proposals. Stefano Zedda’s research interests include banking, financial mathematics, and statistics, specifically simulation of banking and financial systems stability, banking regulation impact assessment, and interactive agent simulation.

Provides well-organized coverage of statistical analysis and applications in biology, kinesiology, and physical anthropology with comprehensive insights into the techniques and interpretations of R, SPSS®, Excel®, and Numbers® output An Introduction to Statistical Analysis in Research: With Applications in the Biological and Life Sciences develops a conceptual foundation in statistical analysis while providing readers with opportunities to practice these skills via research-based data sets in biology, kinesiology, and physical anthropology. Readers are provided with a detailed introduction and orientation to statistical analysis as well as practical examples to ensure a thorough understanding of the concepts and methodology. In addition, the book addresses not just the statistical concepts researchers should be familiar with, but also demonstrates their relevance to real-world research questions and how to perform them using easily available software packages including R, SPSS®, Excel®, and Numbers®. Specific emphasis is on the practical application of statistics in the biological and life sciences, while enhancing reader skills in identifying the research questions and testable hypotheses, determining the appropriate experimental methodology and statistical analyses, processing data, and reporting the research outcomes. In addition, this book: • Aims to develop readers’ skills including how to report research outcomes, determine the appropriate experimental methodology and statistical analysis, and identify the needed research questions and testable hypotheses • Includes pedagogical elements throughout that enhance the overall learning experience including case studies and tutorials, all in an effort to gain full comprehension of designing an experiment, considering biases and uncontrolled variables, analyzing data, and applying the appropriate statistical application with valid justification • Fills the gap between theoretically driven, mathematically heavy texts and introductory, step-by-step type books while preparing readers with the programming skills needed to carry out basic statistical tests, build support figures, and interpret the results • Provides a companion website that features related R, SPSS, Excel, and Numbers data sets, sample PowerPoint® lecture slides, end of the chapter review questions, software video tutorials that highlight basic statistical concepts, and a student workbook and instructor manual An Introduction to Statistical Analysis in Research: With Applications in the Biological and Life Sciences is an ideal textbook for upper-undergraduate and graduate-level courses in research methods, biostatistics, statistics, biology, kinesiology, sports science and medicine, health and physical education, medicine, and nutrition. The book is also appropriate as a reference for researchers and professionals in the fields of anthropology, sports research, sports science, and physical education. KATHLEEN F. WEAVER, PhD, is Associate Dean of Learning, Innovation, and Teaching and Professor in the Department of Biology at the University of La Verne. The author of numerous journal articles, she received her PhD in Ecology and Evolutionary Biology from the University of Colorado. VANESSA C. MORALES, BS, is Assistant Director of the Academic Success Center at the University of La Verne. SARAH L. DUNN, PhD, is Associate Professor in the Department of Kinesiology at the University of La Verne and is Director of Research and Sponsored Programs. She has authored numerous journal articles and received her PhD in Health and Exercise Science from the University of New South Wales. KANYA GODDE, PhD, is Assistant Professor in the Department of Anthropology and is Director/Chair of Institutional Review Board at the University of La Verne. The author of numerous j

Introducing a revolutionary new model for the statistical analysis of experimental data In this important book, internationally acclaimed statistician, Chihiro Hirotsu, goes beyond classical analysis of variance (ANOVA) model to offer a unified theory and advanced techniques for the statistical analysis of experimental data. Dr. Hirotsu introduces the groundbreaking concept of advanced analysis of variance (AANOVA) and explains how the AANOVA approach exceeds the limitations of ANOVA methods to allow for global reasoning utilizing special methods of simultaneous inference leading to individual conclusions. Focusing on normal, binomial, and categorical data, Dr. Hirotsu explores ANOVA theory and practice and reviews current developments in the field. He then introduces three new advanced approaches, namely: testing for equivalence and non-inferiority; simultaneous testing for directional (monotonic or restricted) alternatives and change-point hypotheses; and analyses emerging from categorical data. Using real-world examples, he shows how these three recognizable families of problems have important applications in most practical activities involving experimental data in an array of research areas, including bioequivalence, clinical trials, industrial experiments, pharmaco-statistics, and quality control, to name just a few. • Written in an expository style which will encourage readers to explore applications for AANOVA techniques in their own research • Focuses on dealing with real data, providing real-world examples drawn from the fields of statistical quality control, clinical trials, and drug testing • Describes advanced methods developed and refined by the author over the course of his long career as research engineer and statistician • Introduces advanced technologies for AANOVA data analysis that build upon the basic ANOVA principles and practices Introducing a breakthrough approach to statistical analysis which overcomes the limitations of the ANOVA model, Advanced Analysis of Variance is an indispensable resource for researchers and practitioners working in fields within which the statistical analysis of experimental data is a crucial research component. Chihiro Hirotsu is a Senior Researcher at the Collaborative Research Center, Meisei University, and Professor Emeritus at the University of Tokyo. He is a fellow of the American Statistical Association, an elected member of the International Statistical Institute, and he has been awarded the Japan Statistical Society Prize (2005) and the Ouchi Prize (2006). His work has been published in Biometrika, Biometrics, and Computational Statistics & Data Analysis, among other premier research journals.

Praise from the Second Edition «…an excellent introduction to optimization theory…» (Journal of Mathematical Psychology, 2002) «A textbook for a one-semester course on optimization theory and methods at the senior undergraduate or beginning graduate level.» (SciTech Book News, Vol. 26, No. 2, June 2002) Explore the latest applications of optimization theory and methods Optimization is central to any problem involving decision making in many disciplines, such as engineering, mathematics, statistics, economics, and computer science. Now, more than ever, it is increasingly vital to have a firm grasp of the topic due to the rapid progress in computer technology, including the development and availability of user-friendly software, high-speed and parallel processors, and networks. Fully updated to reflect modern developments in the field, An Introduction to Optimization, Third Edition fills the need for an accessible, yet rigorous, introduction to optimization theory and methods. The book begins with a review of basic definitions and notations and also provides the related fundamental background of linear algebra, geometry, and calculus. With this foundation, the authors explore the essential topics of unconstrained optimization problems, linear programming problems, and nonlinear constrained optimization. An optimization perspective on global search methods is featured and includes discussions on genetic algorithms, particle swarm optimization, and the simulated annealing algorithm. In addition, the book includes an elementary introduction to artificial neural networks, convex optimization, and multi-objective optimization, all of which are of tremendous interest to students, researchers, and practitioners. Additional features of the Third Edition include: New discussions of semidefinite programming and Lagrangian algorithms A new chapter on global search methods A new chapter on multipleobjective optimization New and modified examples and exercises in each chapter as well as an updated bibliography containing new references An updated Instructor's Manual with fully worked-out solutions to the exercises Numerous diagrams and figures found throughout the text complement the written presentation of key concepts, and each chapter is followed by MATLAB exercises and drill problems that reinforce the discussed theory and algorithms. With innovative coverage and a straightforward approach, An Introduction to Optimization, Third Edition is an excellent book for courses in optimization theory and methods at the upper-undergraduate and graduate levels. It also serves as a useful, self-contained reference for researchers and professionals in a wide array of fields.

A broad introduction to PDEs with an emphasis on specialized topics and applications occurring in a variety of fields Featuring a thoroughly revised presentation of topics, Beginning Partial Differential Equations, Third Edition provides a challenging, yet accessible, combination of techniques, applications, and introductory theory on the subjectof partial differential equations. The new edition offers nonstandard coverageon material including Burger’s equation, the telegraph equation, damped wavemotion, and the use of characteristics to solve nonhomogeneous problems. The Third Edition is organized around four themes: methods of solution for initial-boundary value problems; applications of partial differential equations; existence and properties of solutions; and the use of software to experiment with graphics and carry out computations. With a primary focus on wave and diffusion processes, Beginning Partial Differential Equations, Third Edition also includes: Proofs of theorems incorporated within the topical presentation, such as the existence of a solution for the Dirichlet problem The incorporation of Maple™ to perform computations and experiments Unusual applications, such as Poe’s pendulum Advanced topical coverage of special functions, such as Bessel, Legendre polynomials, and spherical harmonics Fourier and Laplace transform techniques to solve important problems Beginning of Partial Differential Equations, Third Edition is an ideal textbook for upper-undergraduate and first-year graduate-level courses in analysis and applied mathematics, science, and engineering.

A mathematical introduction to the theory and applications of logic and set theory with an emphasis on writing proofs Highlighting the applications and notations of basic mathematical concepts within the framework of logic and set theory, A First Course in Mathematical Logic and Set Theory introduces how logic is used to prepare and structure proofs and solve more complex problems. The book begins with propositional logic, including two-column proofs and truth table applications, followed by first-order logic, which provides the structure for writing mathematical proofs. Set theory is then introduced and serves as the basis for defining relations, functions, numbers, mathematical induction, ordinals, and cardinals. The book concludes with a primer on basic model theory with applications to abstract algebra. A First Course in Mathematical Logic and Set Theory also includes: Section exercises designed to show the interactions between topics and reinforce the presented ideas and concepts Numerous examples that illustrate theorems and employ basic concepts such as Euclid’s lemma, the Fibonacci sequence, and unique factorization Coverage of important theorems including the well-ordering theorem, completeness theorem, compactness theorem, as well as the theorems of L?wenheim–Skolem, Burali-Forti, Hartogs, Cantor–Schr?der–Bernstein, and K?nig An excellent textbook for students studying the foundations of mathematics and mathematical proofs, A First Course in Mathematical Logic and Set Theory is also appropriate for readers preparing for careers in mathematics education or computer science. In addition, the book is ideal for introductory courses on mathematical logic and/or set theory and appropriate for upper-undergraduate transition courses with rigorous mathematical reasoning involving algebra, number theory, or analysis.

Written by a team of international experts, Extremes and Recurrence in Dynamical Systems presents a unique point of view on the mathematical theory of extremes and on its applications in the natural and social sciences. Featuring an interdisciplinary approach to new concepts in pure and applied mathematical research, the book skillfully combines the areas of statistical mechanics, probability theory, measure theory, dynamical systems, statistical inference, geophysics, and software application. Emphasizing the statistical mechanical point of view, the book introduces robust theoretical embedding for the application of extreme value theory in dynamical systems. Extremes and Recurrence in Dynamical Systems also features: • A careful examination of how a dynamical system can serve as a generator of stochastic processes • Discussions on the applications of statistical inference in the theoretical and heuristic use of extremes • Several examples of analysis of extremes in a physical and geophysical context • A final summary of the main results presented along with a guide to future research projects • An appendix with software in Matlab® programming language to help readers to develop further understanding of the presented concepts Extremes and Recurrence in Dynamical Systems is ideal for academics and practitioners in pure and applied mathematics, probability theory, statistics, chaos, theoretical and applied dynamical systems, statistical mechanics, geophysical fluid dynamics, geosciences and complexity science. VALERIO LUCARINI, PhD, is Professor of Theoretical Meteorology at the University of Hamburg, Germany and Professor of Statistical Mechanics at the University of Reading, UK. DAVIDE FARANDA, PhD, is Researcher at the Laboratoire des science du climat et de l’environnement, IPSL, CEA Saclay, Universit? Paris-Saclay, Gif-sur-Yvette, France. ANA CRISTINA GOMES MONTEIRO MOREIRA DE FREITAS, PhD, is Assistant Professor in the Faculty of Economics at the University of Porto, Portugal. JORGE MIGUEL MILHAZES DE FREITAS, PhD, is Assistant Professor in the Department of Mathematics of the Faculty of Sciences at the University of Porto, Portugal. MARK HOLLAND, PhD, is Senior Lecturer in Applied Mathematics in the College of Engineering, Mathematics and Physical Sciences at the University of Exeter, UK. TOBIAS KUNA, PhD, is Associate Professor in the Department of Mathematics and Statistics at the University of Reading, UK. MATTHEW NICOL, PhD, is Professor of Mathematics at the University of Houston, USA. MIKE TODD, PhD, is Lecturer in the School of Mathematics and Statistics at the University of St. Andrews, Scotland. SANDRO VAIENTI, PhD, is Professor of Mathematics at the University of Toulon and Researcher at the Centre de Physique Th?orique, France.

Features the classical themes of geometry with plentiful applications in mathematics, education, engineering, and science Accessible and reader-friendly, Classical Geometry: Euclidean, Transformational, Inversive, and Projective introduces readers to a valuable discipline that is crucial to understanding bothspatial relationships and logical reasoning. Focusing on the development of geometric intuitionwhile avoiding the axiomatic method, a problem solving approach is encouraged throughout. The book is strategically divided into three sections: Part One focuses on Euclidean geometry, which provides the foundation for the rest of the material covered throughout; Part Two discusses Euclidean transformations of the plane, as well as groups and their use in studying transformations; and Part Three covers inversive and projective geometry as natural extensions of Euclidean geometry. In addition to featuring real-world applications throughout, Classical Geometry: Euclidean, Transformational, Inversive, and Projective includes: Multiple entertaining and elegant geometry problems at the end of each section for every level of study Fully worked examples with exercises to facilitate comprehension and retention Unique topical coverage, such as the theorems of Ceva and Menalaus and their applications An approach that prepares readers for the art of logical reasoning, modeling, and proofs The book is an excellent textbook for courses in introductory geometry, elementary geometry, modern geometry, and history of mathematics at the undergraduate level for mathematics majors, as well as for engineering and secondary education majors. The book is also ideal for anyone who would like to learn the various applications of elementary geometry.

"This book should have a place on the bookshelf of every forensic scientist who cares about the science of evidence interpretation" Dr. Ian Evett, Principal Forensic Services Ltd, London, UK Continuing developments in science and technology mean that the amounts of information forensic scientists are able to provide for criminal investigations is ever increasing. The commensurate increase in complexity creates difficulties for scientists and lawyers with regard to evaluation and interpretation, notably with respect to issues of inference and decision. Probability theory, implemented through graphical methods, and specifically Bayesian networks, provides powerful methods to deal with this complexity. Extensions of these methods to elements of decision theory provide further support and assistance to the judicial system. Bayesian Networks for Probabilistic Inference and Decision Analysis in Forensic Science provides a unique and comprehensive introduction to the use of Bayesian decision networks for the evaluation and interpretation of scientific findings in forensic science, and for the support of decision-makers in their scientific and legal tasks. • Includes self-contained introductions to probability and decision theory. • Develops the characteristics of Bayesian networks, object-oriented Bayesian networks and their extension to decision models. • Features implementation of the methodology with reference to commercial and academically available software. • Presents standard networks and their extensions that can be easily implemented and that can assist in the reader’s own analysis of real cases. • Provides a technique for structuring problems and organizing data based on methods and principles of scientific reasoning. • Contains a method for the construction of coherent and defensible arguments for the analysis and evaluation of scientific findings and for decisions based on them. • Is written in a lucid style, suitable for forensic scientists and lawyers with minimal mathematical background. • Includes a foreword by Ian Evett. The clear and accessible style of this second edition makes this book ideal for all forensic scientists, applied statisticians and graduate students wishing to evaluate forensic findings from the perspective of probability and decision analysis. It will also appeal to lawyers and other scientists and professionals interested in the evaluation and interpretation of forensic findings, including decision making based on scientific information.

Bayesian analysis of complex models based on stochastic processes has in recent years become a growing area. This book provides a unified treatment of Bayesian analysis of models based on stochastic processes, covering the main classes of stochastic processing including modeling, computational, inference, forecasting, decision making and important applied models. Key features: Explores Bayesian analysis of models based on stochastic processes, providing a unified treatment. Provides a thorough introduction for research students. Computational tools to deal with complex problems are illustrated along with real life case studies Looks at inference, prediction and decision making. Researchers, graduate and advanced undergraduate students interested in stochastic processes in fields such as statistics, operations research (OR), engineering, finance, economics, computer science and Bayesian analysis will benefit from reading this book. With numerous applications included, practitioners of OR, stochastic modelling and applied statistics will also find this book useful.

A comprehensive introduction to statistical methods for data mining and knowledge discovery. Applications of data mining and ‘big data’ increasingly take center stage in our modern, knowledge-driven society, supported by advances in computing power, automated data acquisition, social media development and interactive, linkable internet software. This book presents a coherent, technical introduction to modern statistical learning and analytics, starting from the core foundations of statistics and probability. It includes an overview of probability and statistical distributions, basics of data manipulation and visualization, and the central components of standard statistical inferences. The majority of the text extends beyond these introductory topics, however, to supervised learning in linear regression, generalized linear models, and classification analytics. Finally, unsupervised learning via dimension reduction, cluster analysis, and market basket analysis are introduced. Extensive examples using actual data (with sample R programming code) are provided, illustrating diverse informatic sources in genomics, biomedicine, ecological remote sensing, astronomy, socioeconomics, marketing, advertising and finance, among many others. Statistical Data Analytics: Focuses on methods critically used in data mining and statistical informatics. Coherently describes the methods at an introductory level, with extensions to selected intermediate and advanced techniques. Provides informative, technical details for the highlighted methods. Employs the open-source R language as the computational vehicle – along with its burgeoning collection of online packages – to illustrate many of the analyses contained in the book. Concludes each chapter with a range of interesting and challenging homework exercises using actual data from a variety of informatic application areas. This book will appeal as a classroom or training text to intermediate and advanced undergraduates, and to beginning graduate students, with sufficient background in calculus and matrix algebra. It will also serve as a source-book on the foundations of statistical informatics and data analytics to practitioners who regularly apply statistical learning to their modern data.

The definitive introduction to data analysis in quantitative proteomics This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author’s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers. Computational and Statistical Methods for Protein Quantification by Mass Spectrometry: Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs. Is illustrated by a large number of figures and examples as well as numerous exercises. Provides both clear and rigorous descriptions of methods and approaches. Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work. Features detailed discussions of both wet-lab approaches and statistical and computational methods. With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.

Bayesian methods are increasingly being used in the social sciences, as the problems encountered lend themselves so naturally to the subjective qualities of Bayesian methodology. This book provides an accessible introduction to Bayesian methods, tailored specifically for social science students. It contains lots of real examples from political science, psychology, sociology, and economics, exercises in all chapters, and detailed descriptions of all the key concepts, without assuming any background in statistics beyond a first course. It features examples of how to implement the methods using WinBUGS – the most-widely used Bayesian analysis software in the world – and R – an open-source statistical software. The book is supported by a Website featuring WinBUGS and R code, and data sets.

This is the first text to examine the use of statistical methods in forensic science and bayesian statistics in combination. The book is split into two parts: Part One concentrates on the philosophies of statistical inference. Chapter One examines the differences between the frequentist, the likelihood and the Bayesian perspectives, before Chapter Two explores the Bayesian decision-theoretic perspective further, and looks at the benefits it carries. Part Two then introduces the reader to the practical aspects involved: the application, interpretation, summary and presentation of data analyses are all examined from a Bayesian decision-theoretic perspective. A wide range of statistical methods, essential in the analysis of forensic scientific data is explored. These include the comparison of allele proportions in populations, the comparison of means, the choice of sampling size, and the discrimination of items of evidence of unknown origin into predefined populations. Throughout this practical appraisal there are a wide variety of examples taken from the routine work of forensic scientists. These applications are demonstrated in the ever-more popular R language. The reader is taken through these applied examples in a step-by-step approach, discussing the methods at each stage.

Assessment Methods in Statistical Education: An International Perspective provides a modern, international perspective on assessing students of statistics in higher education. It is a collection of contributions written by some of the leading figures in statistical education from around the world, drawing on their personal teaching experience and educational research. The book reflects the wide variety of disciplines, such as business, psychology and the health sciences, which include statistics teaching and assessment. The authors acknowledge the increasingly important role of technology in assessment, whether it be using the internet for accessing information and data sources or using software to construct and manage individualised or online assessments. Key Features: Presents successful assessment strategies, striking a balance between formative and summative assessment, individual and group work, take-away assignments and supervised tests. Assesses statistical thinking by questioning students’ ability to interpret and communicate the results of their analysis. Relates assessment to the real world by basing it on real data in an appropriate context. Provides a range of individualised assessment methods, including those that deter plagiarism and collusion by providing each student with a unique problem to solve or dataset to analyse. This book is essential reading for anyone involved in teaching statistics at tertiary level or interested in statistical education research.

A thorough introduction to the theory of complex functions emphasizing the beauty, power, and counterintuitive nature of the subject Written with a reader-friendly approach, Complex Analysis: A Modern First Course in Function Theory features a self-contained, concise development of the fundamental principles of complex analysis. After laying groundwork on complex numbers and the calculus and geometric mapping properties of functions of a complex variable, the author uses power series as a unifying theme to define and study the many rich and occasionally surprising properties of analytic functions, including the Cauchy theory and residue theorem. The book concludes with a treatment of harmonic functions and an epilogue on the Riemann mapping theorem. Thoroughly classroom tested at multiple universities, Complex Analysis: A Modern First Course in Function Theory features: Plentiful exercises, both computational and theoretical, of varying levels of difficulty, including several that could be used for student projects Numerous figures to illustrate geometric concepts and constructions used in proofs Remarks at the conclusion of each section that place the main concepts in context, compare and contrast results with the calculus of real functions, and provide historical notes Appendices on the basics of sets and functions and a handful of useful results from advanced calculus Appropriate for students majoring in pure or applied mathematics as well as physics or engineering, Complex Analysis: A Modern First Course in Function Theory is an ideal textbook for a one-semester course in complex analysis for those with a strong foundation in multivariable calculus. The logically complete book also serves as a key reference for mathematicians, physicists, and engineers and is an excellent source for anyone interested in independently learning or reviewing the beautiful subject of complex analysis.

Praise for the First Edition “…this book is quite inspiring, giving many practical ideas for survey research, especially for designing better questionnaires.” —International Statistical Review Reflecting modern developments in the field of survey research, the Second Edition of Design, Evaluation, and Analysis of Questionnaires for Survey Research continues to provide cutting-edge analysis of the important decisions researchers make throughout the survey design process. The new edition covers the essential methodologies and statistical tools utilized to create reliable and accurate survey questionnaires, which unveils the relationship between individual question characteristics and overall question quality. Since the First Edition, the computer program Survey Quality Prediction (SQP) has been updated to include new predictions of the quality of survey questions on the basis of analyses of Multi-Trait Multi-Method experiments. The improved program contains over 60,000 questions, with translations in most European languages. Featuring an expanded explanation of the usage and limitations of SQP 2.0, the Second Edition also includes: • New practice problems to provide readers with real-world experience in survey research and questionnaire design • A comprehensive outline of the steps for creating and testing survey questionnaires • Contemporary examples that demonstrate the many pitfalls of questionnaire design and ways to avoid similar decisions Design, Evaluation, and Analysis of Questionnaires for Survey Research, Second Edition is an excellent textbook for upper-undergraduate and graduate-level courses in methodology and research questionnaire planning, as well as an ideal resource for social scientists or survey researchers needing to design, evaluate, and analyze questionnaires. Design, Evaluation, and Analysis of Questionnaires for Survey Research, Second Edition is an excellent textbook for upper-undergraduate and graduate-level courses in methodology and research questionnaire planning, as well as an ideal resource for social scientists or survey researchers needing to design, evaluate, and analyze questionnaires.Reflecting modern developments in the field of survey research, the Second Edition ofDesign, Evaluation, and Analysis of Questionnaires for Survey Research continues toprovide cutting-edge analysis of the important decisions researchers make throughout thesurvey design process.The new edition covers the essential methodologies and statistical tools utilized to createreliable and accurate survey questionnaires, which unveils the relationship between individualquestion characteristics and overall question quality. Since the First Edition, the computerprogram Survey Quality Prediction (SQP) has

Statistical Methods in Customer Relationship Management focuses on the quantitative and modeling aspects of customer management strategies that lead to future firm profitability, with emphasis on developing an understanding of Customer Relationship Management (CRM) models as the guiding concept for profitable customer management. To understand and explore the functioning of CRM models, this book traces the management strategies throughout a customer’s tenure with a firm. Furthermore, the book explores in detail CRM models for customer acquisition, customer retention, customer acquisition and retention, customer churn, and customer win back. Statistical Methods in Customer Relationship Management: Provides an overview of a CRM system, introducing key concepts and metrics needed to understand and implement these models. Focuses on five CRM models: customer acquisition, customer retention, customer churn, and customer win back with supporting case studies. Explores each model in detail, from investigating the need for CRM models to looking at the future of the models. Presents models and concepts that span across the introductory, advanced, and specialist levels. Academics and practitioners involved in the area of CRM as well as instructors of applied statistics and quantitative marketing courses will benefit from this book.

Provides an accessible foundation to Bayesian analysis using real world models This book aims to present an introduction to Bayesian modelling and computation, by considering real case studies drawn from diverse fields spanning ecology, health, genetics and finance. Each chapter comprises a description of the problem, the corresponding model, the computational method, results and inferences as well as the issues that arise in the implementation of these approaches. Case Studies in Bayesian Statistical Modelling and Analysis: Illustrates how to do Bayesian analysis in a clear and concise manner using real-world problems. Each chapter focuses on a real-world problem and describes the way in which the problem may be analysed using Bayesian methods. Features approaches that can be used in a wide area of application, such as, health, the environment, genetics, information science, medicine, biology, industry and remote sensing. Case Studies in Bayesian Statistical Modelling and Analysis is aimed at statisticians, researchers and practitioners who have some expertise in statistical modelling and analysis, and some understanding of the basics of Bayesian statistics, but little experience in its application. Graduate students of statistics and biostatistics will also find this book beneficial.

A key resource and framework for assessing the performance of competing entities, including forecasting models Advances in DEA Theory and Applications provides a much-needed framework for assessing the performance of competing entities with special emphasis on forecasting models. It helps readers to determine the most appropriate methodology in order to make the most accurate decisions for implementation. Written by a noted expert in the field, this text provides a review of the latest advances in DEA theory and applications to the field of forecasting. Designed for use by anyone involved in research in the field of forecasting or in another application area where forecasting drives decision making, this text can be applied to a wide range of contexts, including education, health care, banking, armed forces, auditing, market research, retail outlets, organizational effectiveness, transportation, public housing, and manufacturing. This vital resource: Explores the latest developments in DEA frameworks for the performance evaluation of entities such as public or private organizational branches or departments, economic sectors, technologies, and stocks Presents a novel area of application for DEA; namely, the performance evaluation of forecasting models Promotes the use of DEA to assess the performance of forecasting models in a wide area of applications Provides rich, detailed examples and case studies Advances in DEA Theory and Applications includes information on a balanced benchmarking tool that is designed to help organizations examine their assumptions about their productivity and performance.

Data mining is well on its way to becoming a recognized discipline in the overlapping areas of IT, statistics, machine learning, and AI. Practical Data Mining for Business presents a user-friendly approach to data mining methods, covering the typical uses to which it is applied. The methodology is complemented by case studies to create a versatile reference book, allowing readers to look for specific methods as well as for specific applications. The book is formatted to allow statisticians, computer scientists, and economists to cross-reference from a particular application or method to sectors of interest.

This insightful book combines the history, pedagogy, and popularization of algebra to present a unified discussion of the subject. Classical Algebra provides a complete and contemporary perspective on classical polynomial algebra through the exploration of how it was developed and how it exists today. With a focus on prominent areas such as the numerical solutions of equations, the systematic study of equations, and Galois theory, this book facilitates a thorough understanding of algebra and illustrates how the concepts of modern algebra originally developed from classical algebraic precursors. This book successfully ties together the disconnect between classical and modern algebraand provides readers with answers to many fascinating questions that typically go unexamined, including: What is algebra about? How did it arise? What uses does it have? How did it develop? What problems and issues have occurred in its history? How were these problems and issues resolved? The author answers these questions and more, shedding light on a rich history of the subject—from ancient and medieval times to the present. Structured as eleven «lessons» that are intended to give the reader further insight on classical algebra, each chapter contains thought-provoking problems and stimulating questions, for which complete answers are provided in an appendix. Complemented with a mixture of historical remarks and analyses of polynomial equations throughout, Classical Algebra: Its Nature, Origins, and Uses is an excellent book for mathematics courses at the undergraduate level. It also serves as a valuable resource to anyone with a general interest in mathematics.

This book is organized in two parts: the first part introduces the reader to all the concepts, tools and references that are required to start conducting research in behavioral computational social science. The methodological reasons for integrating the two approaches are also presented from the individual and separated viewpoints of the two approaches.The second part of the book, presents all the advanced methodological and technical aspects that are relevant for the proposed integration. Several contributions which effectively merge the computational and the behavioral approaches are presented and discussed throughout

Data Mining Algorithms is a practical, technically-oriented guide to data mining algorithms that covers the most important algorithms for building classification, regression, and clustering models, as well as techniques used for attribute selection and transformation, model quality evaluation, and creating model ensembles. The author presents many of the important topics and methodologies widely used in data mining, whilst demonstrating the internal operation and usage of data mining algorithms using examples in R.

An easy-to-read presentation of the early history of mathematics Engaging and accessible, An Introduction to the Early Development of Mathematics provides a captivating introduction to the history of ancient mathematics in early civilizations for a nontechnical audience. Written with practical applications in a variety of areas, the book utilizes the historical context of mathematics as a pedagogical tool to assist readers working through mathematical and historical topics. The book is divided into sections on significant early civilizations including Egypt, Babylonia, China, Greece, India, and the Islamic world. Beginning each chapter with a general historical overview of the civilized area, the author highlights the civilization’s mathematical techniques, number representations, accomplishments, challenges, and contributions to the mathematical world. Thoroughly class-tested, An Introduction to the Early Development of Mathematics features: Challenging exercises that lead readers to a deeper understanding of mathematics Numerous relevant examples and problem sets with detailed explanations of the processes and solutions at the end of each chapter Additional references on specific topics and keywords from history, archeology, religion, culture, and mathematics Examples of practical applications with step-by-step explanations of the mathematical concepts and equations through the lens of early mathematical problems A companion website that includes additional exercises An Introduction to the Early Development of Mathematics is an ideal textbook for undergraduate courses on the history of mathematics and a supplement for elementary and secondary education majors. The book is also an appropriate reference for professional and trade audiences interested in the history of mathematics. Michael K. J. Goodman is Adjunct Mathematics Instructor at Westchester Community College, where he teaches courses in the history of mathematics, contemporary mathematics, and algebra. He is also the owner and operator of The Learning Miracle, LLC, which provides academic tutoring and test preparation for both college and high school students.

A comprehensive and accessible introduction to modern quantitative risk management. The business world is rife with risk and uncertainty, and risk management is a vitally important topic for managers. The best way to achieve a clear understanding of risk is to use quantitative tools and probability models. Written for students, this book has a quantitative emphasis but is accessible to those without a strong mathematical background. Business Risk Management: Models and Analysis Discusses novel modern approaches to risk management Introduces advanced topics in an accessible manner Includes motivating worked examples and exercises (including selected solutions) Is written with the student in mind, and does not assume advanced mathematics Is suitable for self-study by the manager who wishes to better understand this important field. Aimed at postgraduate students, this book is also suitable for senior undergraduates, MBA students, and all those who have a general interest in business risk.

Drawing on essays from leading international and multi-disciplinary scholars, A Companion to the Philosophy of Technology is the first comprehensive and authoritative reference source to cover the key issues of technology’s impact on society and our lives. Presents the first complete, authoritative reference work in the field Organized thematically for use both as a full introduction to the field or an encyclopedic reference Draws on original essays from leading interdisciplinary scholars Features the most up-to-date and cutting edge research in the interdisciplinary fields of philosophy, technology, and their broader intellectual environments