Bayesian Statistical Modelling

Provides an accessible foundation to Bayesian analysis using real world models This book aims to present an introduction to Bayesian modelling and computation, by considering real case studies drawn from diverse fields spanning ecology, health, genetics and finance. Each chapter comprises a description of the problem, the corresponding model, the computational method, results and inferences as well as the issues that arise in the implementation of these approaches. Case Studies in Bayesian Statistical Modelling and Analysis: Illustrates how to do Bayesian analysis in a clear and concise manner using real-world problems. Each chapter focuses on a real-world problem and describes the way in which the problem may be analysed using Bayesian methods. Features approaches that can be used in a wide area of application, such as, health, the environment, genetics, information science, medicine, biology, industry and remote sensing. Case Studies in Bayesian Statistical Modelling and Analysis is aimed at statisticians, researchers and practitioners who have some expertise in statistical modelling and analysis, and some understanding of the basics of Bayesian statistics, but little experience in its application. Graduate students of statistics and biostatistics will also find this book beneficial.

This book provides an accessible approach to Bayesian computing and data analysis, with an emphasis on the interpretation of real data sets. Following in the tradition of the successful first edition, this book aims to make a wide range of statistical modeling applications accessible using tested code that can be readily adapted to the reader's own applications. The second edition has been thoroughly reworked and updated to take account of advances in the field. A new set of worked examples is included. The novel aspect of the first edition was the coverage of statistical modeling using WinBUGS and OPENBUGS. This feature continues in the new edition along with examples using R to broaden appeal and for completeness of coverage.

Spatial point processes are mathematical models used to describe and analyse the geometrical structure of patterns formed by objects that are irregularly or randomly distributed in one-, two- or three-dimensional space. Examples include locations of trees in a forest, blood particles on a glass plate, galaxies in the universe, and particle centres in samples of material. Numerous aspects of the nature of a specific spatial point pattern may be described using the appropriate statistical methods. Statistical Analysis and Modelling of Spatial Point Patterns provides a practical guide to the use of these specialised methods. The application-oriented approach helps demonstrate the benefits of this increasingly popular branch of statistics to a broad audience. The book: Provides an introduction to spatial point patterns for researchers across numerous areas of application Adopts an extremely accessible style, allowing the non-statistician complete understanding Describes the process of extracting knowledge from the data, emphasising the marked point process Demonstrates the analysis of complex datasets, using applied examples from areas including biology, forestry, and materials science Features a supplementary website containing example datasets. Statistical Analysis and Modelling of Spatial Point Patterns is ideally suited for researchers in the many areas of application, including environmental statistics, ecology, physics, materials science, geostatistics, and biology. It is also suitable for students of statistics, mathematics, computer science, biology and geoinformatics.

The first all-inclusive introduction to modern statistical research methods in the natural resource sciences The use of Bayesian statistical analysis has become increasingly important to natural resource scientists as a practical tool for solving various research problems. However, many important contemporary methods of applied statistics, such as generalized linear modeling, mixed-effects modeling, and Bayesian statistical analysis and inference, remain relatively unknown among researchers and practitioners in this field. Through its inclusive, hands-on treatment of real-world examples, Contemporary Bayesian and Frequentist Statistical Research Methods for Natural Resource Scientists successfully introduces the key concepts of statistical analysis and inference with an accessible, easy-to-follow approach. The book provides case studies illustrating common problems that exist in the natural resource sciences and presents the statistical knowledge and tools needed for a modern treatment of these issues. Subsequent chapter coverage features: An introduction to the fundamental concepts of Bayesian statistical analysis, including its historical background, conjugate solutions, Bayesian hypothesis testing and decision-making, and Markov Chain Monte Carlo solutions The relevant advantages of using Bayesian statistical analysis, rather than the traditional frequentist approach, to address research problems Two alternative strategies?€”the a posteriori model selection strategy and the a priori parsimonious model selection strategy using AIC and DIC?€”to model selection and inference The ideas of generalized linear modeling (GLM), focusing on the most popular GLM of logistic regression An introduction to mixed-effects modeling in S-Plus?® and R for analyzing natural resource data sets with varying error structures and dependencies Each statistical concept is accompanied by an illustration of its frequentist application in S-Plus?® or R as well as its Bayesian application in WinBUGS. Brief introductions to these software packages are also provided to help the reader fully understand the concepts of the statistical methods that are presented throughout the book. Assuming only a minimal background in introductory statistics, Contemporary Bayesian and Frequentist Statistical Research Methods for Natural Resource Scientists is an ideal text for natural resource students studying statistical research methods at the upper-undergraduate or graduate level and also serves as a valuable problem-solving guide for natural resource scientists across a broad range of disciplines, including biology, wildlife management, forestry management, fisheries management, and the environmental sciences.

This handbook and ready reference presents a combination of statistical, information-theoretic, and data analysis methods to meet the challenge of designing empirical models involving molecular descriptors within bioinformatics. The topics range from investigating information processing in chemical and biological networks to studying statistical and information-theoretic techniques for analyzing chemical structures to employing data analysis and machine learning techniques for QSAR/QSPR. The high-profile international author and editor team ensures excellent coverage of the topic, making this a must-have for everyone working in chemoinformatics and structure-oriented drug design.

Bayesian Networks, the result of the convergence of artificial intelligence with statistics, are growing in popularity. Their versatility and modelling power is now employed across a variety of fields for the purposes of analysis, simulation, prediction and diagnosis. This book provides a general introduction to Bayesian networks, defining and illustrating the basic concepts with pedagogical examples and twenty real-life case studies drawn from a range of fields including medicine, computing, natural sciences and engineering. Designed to help analysts, engineers, scientists and professionals taking part in complex decision processes to successfully implement Bayesian networks, this book equips readers with proven methods to generate, calibrate, evaluate and validate Bayesian networks. The book: Provides the tools to overcome common practical challenges such as the treatment of missing input data, interaction with experts and decision makers, determination of the optimal granularity and size of the model. Highlights the strengths of Bayesian networks whilst also presenting a discussion of their limitations. Compares Bayesian networks with other modelling techniques such as neural networks, fuzzy logic and fault trees. Describes, for ease of comparison, the main features of the major Bayesian network software packages: Netica, Hugin, Elvira and Discoverer, from the point of view of the user. Offers a historical perspective on the subject and analyses future directions for research. Written by leading experts with practical experience of applying Bayesian networks in finance, banking, medicine, robotics, civil engineering, geology, geography, genetics, forensic science, ecology, and industry, the book has much to offer both practitioners and researchers involved in statistical analysis or modelling in any of these fields.

The growth of biostatistics has been phenomenal in recent years and has been marked by considerable technical innovation in both methodology and computational practicality. One area that has experienced significant growth is Bayesian methods. The growing use of Bayesian methodology has taken place partly due to an increasing number of practitioners valuing the Bayesian paradigm as matching that of scientific discovery. In addition, computational advances have allowed for more complex models to be fitted routinely to realistic data sets. Through examples, exercises and a combination of introductory and more advanced chapters, this book provides an invaluable understanding of the complex world of biomedical statistics illustrated via a diverse range of applications taken from epidemiology, exploratory clinical studies, health promotion studies, image analysis and clinical trials. Key Features: Provides an authoritative account of Bayesian methodology, from its most basic elements to its practical implementation, with an emphasis on healthcare techniques. Contains introductory explanations of Bayesian principles common to all areas of application. Presents clear and concise examples in biostatistics applications such as clinical trials, longitudinal studies, bioassay, survival, image analysis and bioinformatics. Illustrated throughout with examples using software including WinBUGS, OpenBUGS, SAS and various dedicated R programs. Highlights the differences between the Bayesian and classical approaches. Supported by an accompanying website hosting free software and case study guides. Bayesian Biostatistics introduces the reader smoothly into the Bayesian statistical methods with chapters that gradually increase in level of complexity. Master students in biostatistics, applied statisticians and all researchers with a good background in classical statistics who have interest in Bayesian methods will find this book useful.

Presents the Bayesian approach to statistical signal processing for a variety of useful model sets This book aims to give readers a unified Bayesian treatment starting from the basics (Baye’s rule) to the more advanced (Monte Carlo sampling), evolving to the next-generation model-based techniques (sequential Monte Carlo sampling). This next edition incorporates a new chapter on “Sequential Bayesian Detection,” a new section on “Ensemble Kalman Filters” as well as an expansion of Case Studies that detail Bayesian solutions for a variety of applications. These studies illustrate Bayesian approaches to real-world problems incorporating detailed particle filter designs, adaptive particle filters and sequential Bayesian detectors. In addition to these major developments a variety of sections are expanded to “fill-in-the gaps” of the first edition. Here metrics for particle filter (PF) designs with emphasis on classical “sanity testing” lead to ensemble techniques as a basic requirement for performance analysis. The expansion of information theory metrics and their application to PF designs is fully developed and applied. These expansions of the book have been updated to provide a more cohesive discussion of Bayesian processing with examples and applications enabling the comprehension of alternative approaches to solving estimation/detection problems. The second edition of Bayesian Signal Processing features: “Classical” Kalman filtering for linear, linearized, and nonlinear systems; “modern” unscented and ensemble Kalman filters: and the “next-generation” Bayesian particle filters Sequential Bayesian detection techniques incorporating model-based schemes for a variety of real-world problems Practical Bayesian processor designs including comprehensive methods of performance analysis ranging from simple sanity testing and ensemble techniques to sophisticated information metrics New case studies on adaptive particle filtering and sequential Bayesian detection are covered detailing more Bayesian approaches to applied problem solving MATLAB® notes at the end of each chapter help readers solve complex problems using readily available software commands and point out other software packages available Problem sets included to test readers’ knowledge and help them put their new skills into practice Bayesian Signal Processing, Second Edition is written for all students, scientists, and engineers who investigate and apply signal processing to their everyday problems.

Bayesian Networks: An Introduction provides a self-contained introduction to the theory and applications of Bayesian networks, a topic of interest and importance for statisticians, computer scientists and those involved in modelling complex data sets. The material has been extensively tested in classroom teaching and assumes a basic knowledge of probability, statistics and mathematics. All notions are carefully explained and feature exercises throughout. Features include: An introduction to Dirichlet Distribution, Exponential Families and their applications. A detailed description of learning algorithms and Conditional Gaussian Distributions using Junction Tree methods. A discussion of Pearl's intervention calculus, with an introduction to the notion of see and do conditioning. All concepts are clearly defined and illustrated with examples and exercises. Solutions are provided online. This book will prove a valuable resource for postgraduate students of statistics, computer engineering, mathematics, data mining, artificial intelligence, and biology. Researchers and users of comparable modelling or statistical techniques such as neural networks will also find this book of interest.

Modelling has permeated virtually all areas of industrial, environmental, economic, bio-medical or civil engineering: yet the use of models for decision-making raises a number of issues to which this book is dedicated: How uncertain is my model ? Is it truly valuable to support decision-making ? What kind of decision can be truly supported and how can I handle residual uncertainty ? How much refined should the mathematical description be, given the true data limitations ? Could the uncertainty be reduced through more data, increased modeling investment or computational budget ? Should it be reduced now or later ? How robust is the analysis or the computational methods involved ? Should / could those methods be more robust ? Does it make sense to handle uncertainty, risk, lack of knowledge, variability or errors altogether ? How reasonable is the choice of probabilistic modeling for rare events ? How rare are the events to be considered ? How far does it make sense to handle extreme events and elaborate confidence figures ? Can I take advantage of expert / phenomenological knowledge to tighten the probabilistic figures ? Are there connex domains that could provide models or inspiration for my problem ? Written by a leader at the crossroads of industry, academia and engineering, and based on decades of multi-disciplinary field experience, Modelling Under Risk and Uncertainty gives a self-consistent introduction to the methods involved by any type of modeling development acknowledging the inevitable uncertainty and associated risks. It goes beyond the “black-box” view that some analysts, modelers, risk experts or statisticians develop on the underlying phenomenology of the environmental or industrial processes, without valuing enough their physical properties and inner modelling potential nor challenging the practical plausibility of mathematical hypotheses; conversely it is also to attract environmental or engineering modellers to better handle model confidence issues through finer statistical and risk analysis material taking advantage of advanced scientific computing, to face new regulations departing from deterministic design or support robust decision-making. Modelling Under Risk and Uncertainty: Addresses a concern of growing interest for large industries, environmentalists or analysts: robust modeling for decision-making in complex systems. Gives new insights into the peculiar mathematical and computational challenges generated by recent industrial safety or environmental control analysis for rare events. Implements decision theory choices differentiating or aggregating the dimensions of risk/aleatory and epistemic uncertainty through a consistent multi-disciplinary set of statistical estimation, physical modelling, robust computation and risk analysis. Provides an original review of the advanced inverse probabilistic approaches for model identification, calibration or data assimilation, key to digest fast-growing multi-physical data acquisition. Illustrated with one favourite pedagogical example crossing natural risk, engineering and economics, developed throughout the book to facilitate the reading and understanding. Supports Master/PhD-level course as well as advanced tutorials for professional training Analysts and researchers in numerical modeling, applied statistics, scientific computing, reliability, advanced engineering, natural risk or environmental science will benefit from this book.